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具滋權,宋昊哲,金東熙,徐榮培,朴陽春,金聖勳 대한본초학회 2000 大韓本草學會誌 Vol.15 No.1
To evaluate the antitum or activity and immune response Bujungikgibang(BJ1GB) studies were done experimentally. The results were obtained as follows: 1. BJIGB extracts exhibited a weak cytotoxicity against SK-OV-3, and SK-MEL-2 cell lines. While it showed cytotoxicity against B16-Fl0 cell line up to 30% of control at concentration of 0.5 mg/ml. 2. BJIGB extracts significantly showed inhibitoty effect on DNA topoisomerase 1 from calf thymus in a dose-dependant manner. 3. BJIGB extracts showed antiadhesive rates against A549, at 30% at 0.5 mg/ml, 60% at 1 mg/ml 4. BJIGB extracts inhibited CAM angiogenesis up to 60%. 5. BJIGB extracts prolonged life span of ICR mice bearing S-180 sarcoma cells up to 130.5%. 6. In FACS analysis, the population of helper T cell was increased weakly, while cytotoxity T cell was decreased insignificantly. 7. The production of nitric oxide in RAW cell stimulated by LPS was incresed at 0.5mg/ml or more in dose dependant fashion as compared with control. 8. Proliferation rate of splenocyte was increased at 0.5mg/ml or more a dose dependant fashion as compared with control. These results suggested that BJIGB extracts might be usefully applied for treatement of cancer and also it was nesessary to do more studies about its mechnisms.
학교체육 활성화 방안에 대한 연구(Ⅰ) : 강원대학교 교양체육 운영방법의 개선을 중심으로
이광재,문병용,노성규,박기동,홍관이,한상준,유옥재,엄기진,정청자,오수일,김윤래,박장평,부기원 江原大學校附設 體育科學硏究所 1986 江原大學校附設體育科學硏究所論文集 Vol.- No.11
Try to find a scheme for activation to College Physical Education, this Report informs the various kinds of Survey and process those were projected for improvement of management methods on Cultural Physical Education in Kang Weon National University. From experimentally carried out "Sports events Choosing System" not as usual be inforced "Total practical Skill System", Following Positive effects and sujestions were Presented; 1. "Sports events choosing system" gave birth to more students' interesting and more voluntary participation to the sports events they chose, and sports skill and instruction level was elevated due to charge of expert according to each sports events. This system would be managed continuously hereafter for it related to life sports. 2. This System needs to closed cooperations between College and Community, for the facilities of community are utilized by college. 3. To complete the plan for activation of college Physical Education, additionally, the successional study ; namely "autonomous extracurricular sports activity" should be excuted hereafter.
일 의료원의 통합 고충처리센터 접수 내용과 이에 대한 해결방안 분석
탁관철,박현주,천자혜,강은숙,문주영,최미영,김현주,강진경,Tark, Kwan-Chul,Park, Hyun-Ju,Chun, Ja-Hae,Kang, Eun-Sook,Moon, Ju-Young,Choi, Mi-Young,Kim, Hyun-Ju,Kang, Jin-Kyung 한국의료질향상학회 2000 한국의료질향상학회지 Vol.7 No.1
Background : A continuous healthcare quality improvement is needed to provide high quality healthcare service as well as to maintain trust in terms of satisfying the needs of the patients. Recently it also became an essential issue. in hospital management, recognized for it's competitive potentiality among healthcare organization groups. This study was conducted to analyze patient complaints and issues received by the Quality Improvement Department. Its purpose is to improve healthcare qualities within the hospital, as well as establish policies and appropriate strategies in hospital management. Method : From July 1st to September 30th of the year 1999, we analyzed all complaints and issues made by various patients and their families, which were received through 24 hour phone consultation, numerous suggestion boxes, letters and E-mails, The issues were classified into 16 different categories based on a Patient Satisfaction Assessment Tool. All data were segregated according to the departmental frequencies and their contents. To come up with for environmental and patient satisfaction improvement, all complaints or issues were communicated with hospital administrators, medical and nursing staff and employees. Comprehensive customer satisfaction activities including improving phone etiquette were discussed in Customer Satisfaction Team, CQI Team and each Department. All opportunities for improvement were implemented. Feedback actions were discussed. Results : A total of 317 cases were collected. Issues regarding parking and other accommodation facilities were most common complaints that were 14.5% of total. Issues regarding admission rooms (10.7%), admission procedures (10.7%), waiting room environment (8.8%), nurses and nurse assistants (7.6%), physicians (6.6%) and others (23%) followed. Thirteen of 45 departments received more than 8 complaints. The Nursing Department had the most complaint, receiving 9.8% of total complaints. Complaints regarding the Nursing Department were predominantly related to the environment of patient rooms. The Department of Psychiatry for phone etiquette (4.7%), Department of Otolaryngology for the nursing staff's attitude and phone etiquette (4.4%), and the Admission Department followed. As a part of efforts to improve patient satisfaction, a new parking structure was built and reallocation of the parking space was done. Renovation of other accommodation facilities were carried out by hospital administration, Monthly phone call and answering attitude survey was done by QI Department. Based on this survey we made a phone etiquette manual and distributed throughout the hospital. Compare to the last year, Patient Satisfaction Index measured by Korea Productivity Center using National Customer Satisfaction Index was improved 7 points. According to our organization's own study, we confirmed the phone etiquette was improved 11% than last year. Conclusions : Issues related to parking and other accommodation facilities ranked first followed by complaints made regarding the patient care area, the admission and cashier process, and nurses' and doctors' attitude. The Nursing and Psychiatry Departments need improvement regarding phone etiquette. Results were shared and played a vital role in policymaking and strategic planning of the hospital. It is imperative that we keep our database updated by listening to and solving the needs of each patient. The CQI activities can be achieved only by full commitment of the hospital top management supported by related personal.
Analysis of Differentially Expressed Genes in Cloned Bovine Placenta
Park, Hee-Ja,Ko, Yeoung-Gyu,Hwang, Seong-Soo,Yang, Byoung-Chul,Seong, Hwan-Hoo,Oh, Seok-Doo,Hwang, Sue-Yun,Min, Kwan-Sik,Yoon, Jong-Taek The Korean Society of Animal Reproduction 2009 Reproductive & developmental biology Vol.33 No.1
Placenta is the main nutrition source for the fetus during pregnancy. Thus, it has a pivotal function in the pregnant process. Many functions of the placenta have been elucidated. An abnormal placenta is associated with a high rate of pregnancy failure in somatic cloned bovine. Differentially expressed genes (DEGs) were examined in a comparison between normal and cloned bovine placenta using annealing control primer (ACP)-based GeneFishing PCR. Using 120 ACPs, nearly 80 genes were identified and the fragments of 42 DEGs were sequenced. 38 of these genes were known genes and four were unknown. To determine the DEGs result, six target clones expressing on one-side of a normal and a clone placenta were selected. Through an analysis of the target genes using the real-time PCR, the expressing pattern was found to be somewhat different from the DEGs. Additionally, several genes appeared with the same expression pattern. Taken together, this suggests that the target genes would be essential for research into what influences the placental formative mechanisms during fetal development.
Representation of a Conceptual Design for a Rectilinear Motion Polymer Actuator
Ja Choon Koo,Kwang Mok Jung,Jong Kil Park,Jae Do Nam,Young Kwan Lee,Jae Wook Jeon,Hyouk Ryeol Choi 대한전기학회 2007 International Journal of Control, Automation, and Vol.5 No.4
A number of different alternative actuation methods have been under active development for some specific applications where the traditional electromechanical actuators are difficult to apply. Recently, many of these substitutes are trying to employ new smart materials like electroactive polymers. However most of the polymeric materials are flexible and vulnerable so that they normally can not sustain external forces. Although the materials have shown a good potential to be used for alternative actuation mechanisms, no tangible industrial application is yet presented because of the reason. A conceptual design for a rectilinear motion actuator using dielectric elastomer is presented in this article. The introduced design concept might enable to produce fairly controllable rectilinear motions for various applications and the presented prototype actuator system is fully packaged in a small unit and controlled by a standard communication interface.
박문자,정은경,최관모,문경래,박영봉 朝鮮大學校 附設 醫學硏究所 1991 The Medical Journal of Chosun University Vol.15 No.1
The so called "Moyamoya" disease is characterized by idiopathic progressive bilateral occlusion of nternal carotid arteries near the supraclinoid portion, with a distinctive picture of abnormal net like 'essels in the base of the brain. We have experienced a case of Moyamoya disease in a 4Uyear-o1d boy, which was confirmed by left arotid angiography. He was admitted for evaluation and work-up of sudden hemiplegia in the right extremities. The patient was discharged in satisfactory condition with the conservative treatment. Review of literatures and references on Moyamoya disease was done briefly.
Primary malignant melanoma of the small intestine
Kwan Mo Yang,Chan Wook Kim,So-Woon Kim,Jong Lyul Lee,Yong Sik Yoon,In Ja Park,Seok-Byung Lim,Chang Sik Yu,Jin Cheon Kim 대한외과학회 2018 Annals of Surgical Treatment and Research(ASRT) Vol.94 No.5
The majority of malignant melanomas in the small intestine are metastases from primary cutaneous lesions, it can also develop as a primary mucosal tumor in the gastrointestinal tract. In this report, we present rare cases of primary small bowel melanoma and review the current literature. A 78-year-old male presented with abdominal pain and CT enterography identified a ileal mass. A 79-year-old female presented with signs and symptoms of partial small bowel obstruction. Abdominopelvic CT and small bowel series revealed a obstructing mass in the distal jejunum. The masses were confirmed on laparotomy and histologically diagnosed as melanoma. Extensive postoperative clinical examination revealed no cutaneous lesions. A primary small bowel melanoma is an extremely rare neoplasm. A definite diagnosis can only be made after a thorough investigation has been made to exclude the coexistence of a primary lesion. Curative resection of the tumor remains the treatment of choice.