http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Park, Jeong-Nam,Sohn, Min Jeong,Oh, Doo-Byoung,Kwon, Ohsuk,Rhee, Sang Ki,Hur, Cheol-Goo,Lee, Sang Yup,Gellissen, Gerd,Kang, Hyun Ah American Society for Microbiology 2007 Applied and environmental microbiology Vol.73 No.19
<B>ABSTRACT</B><P>The genomewide gene expression profiling of the methylotrophic yeast <I>Hansenula polymorpha</I> exposed to cadmium (Cd) allowed us to identify novel genes responsive to Cd treatment. To select genes whose promoters can be useful for construction of a cellular Cd biosensor, we further analyzed a set of <I>H. polymorpha</I> genes that exhibited >6-fold induction upon treatment with 300 μM Cd for 2 h. The putative promoters, about 1,000-bp upstream fragments, of these genes were fused with the yeast-enhanced green fluorescence protein (GFP) gene. The resultant reporter cassettes were introduced into <I>H. polymorpha</I> to evaluate promoter strength and specificity. The promoter derived from the <I>H. polymorpha SEO1</I> gene (Hp<I>SEO1</I>) was shown to drive most strongly the expression of GFP upon Cd treatment among the tested promoters. The Cd-inducible activity was retained in the 500-bp deletion fragment of the Hp<I>SEO1</I> promoter but was abolished in the further truncated 250-bp fragment. The 500-bp Hp<I>SEO1</I> promoter directed specific expression of GFP upon exposure to Cd in a dose-dependent manner, with Cd detection ranging from 1 to 900 μM. Comparative analysis of the <I>Saccharomyces cerevisiae SEO1</I> (Sc<I>SEO1</I>) promoter revealed that the Sc<I>SEO1</I> promoter has a broader specificity for heavy metals and is responsive to arsenic and mercury in addition to Cd. Our data demonstrate the potential use of the Hp<I>SEO1</I> promoter as a bioelement in whole-cell biosensors to monitor heavy metal contamination, particularly Cd.</P>
Taek Hoon Lee,Ki Yup Nam,김정열 한국망막학회 2019 Journal of Retina Vol.4 No.1
Purpose: To compare pro re nata (PRN) and three scheduled loading injections of intravitreal bevacizumab for macular edema (ME) caused by branch retinal vein occlusion (BRVO). Methods: We retrospectively analyzed the medical records of 96 patients. We compared a group of patients who underwent treatment with intravitreal bevacizumab PRN with a second group that received three scheduled loading injections at 1 month intervals followed by PRN injections. Changes in visual acuity and central retinal thickness (CRT), and the need for additional injections over a 6 month period were compared. Results: The improvement in visual acuity and decrease in CRT were greater in the loading injection group, and the decreases in CRT at the 2, 3, and 6 months were statistically significant. The need for additional injections within 3 months after the last injection was significantly lower in the loading injection group. Conclusions: Over a 6 month period, the three loading injections seemed to be better than PRN injections for the treatment of ME in BRVO with regard to improvements in visual acuity and ME, reducing the need for additional injections within 3 months after the last injection.
Clinical practice guidelines for percutaneous endoscopic gastrostomy
Chung Hyun Tae,Ju Yup Lee,Moon Kyung Joo,Chan Hyuk Park,Eun Jeong Gong,Cheol Min Shin,Hyun Lim,Hyuk Soon Choi,Miyoung Choi,Sang Hoon Kim,Chul-Hyun Lim,Jeong-Sik Byeon,Ki-Nam Shim,Geun Am Song,Moon Sun 대한소화기내시경학회 2023 Clinical Endoscopy Vol.56 No.4
With an aging population, the number of patients with difficulty in swallowing due to medical conditions is gradually increasing. In such cases, enteral nutrition is administered through a temporary nasogastric tube. However, the long-term use of a nasogastric tube leads to various complications and a decreased quality of life. Percutaneous endoscopic gastrostomy (PEG) is the percutaneous placement of a tube into the stomach that is aided endoscopically and may be an alternative to a nasogastric tube when enteral nutritional is required for four weeks or more. This paper is the first Korean clinical guideline for PEG developed jointly by the Korean College of Helicobacter and Upper Gastrointestinal Research and led by the Korean Society of Gastrointestinal Endoscopy. These guidelines aimed to provide physicians, including endoscopists, with the indications, use of prophylactic antibiotics, timing of enteric nutrition, tube placement methods, complications, replacement, and tube removal for PEG based on the currently available clinical evidence.
아메드방수유출장치삽입술 후 발생한 고안압기 환자에서 안구 지압의 효과
남기엽,이종은,김창식,Ki Yup Nam,Jong Eun Lee,Chang Sik Kim 대한안과학회 2011 대한안과학회지 Vol.52 No.3
Purpose: To evaluate the course of the hypertensive phase (HP) after Ahmed glaucoma valve (AGV) implantation and the effects of digital ocular massage. Methods: A total of 131 eyes of 131 patients, who underwent AGV implantation surgery, were studied retrospectively. HP was defined as an IOP (intraocular pressure) ≥ 22 mm Hg within 6 months after surgery. Various clinical factors related to the occurrence of HP were analyzed. The HP group was compared to the non-HP group. Ocular massage was performed in patients showing acute elevation of IOP at a relatively early postoperative period, and the effects were compared with the non-massage group. The patients who received ocular massage were divided, based on its effects, and compared. Results: HP developed in 62.6% of the patients after AGV surgery, and the success rate was significantly lower in the HP group. HP occurred more often in males and in patients with high IOP before surgery. HP developed in 82 eyes at 3.3 weeks after surgery in average. Ocular massage was performed in 30 eyes that showed acute IOP increase. The amount of IOP reduction, compared to 1 month after surgery, was greater in massage group than no massage group from 2 months to 3 years after surgery. Successful IOP control by ocular massage was observed in 14 eyes (46.7%), and the success rate was higher in these patients than the patients who showed no significant IOP reduction by ocular massage. But, the difference was not significant (p = 0.072). Conclusions: HP is related to the final outcome of surgery. Digital ocular massage can be used as an effective method to control HP and prevent further glaucomatous damage. J Korean Ophthalmol Soc 2011;52(3):315-324
세리아가 첨가된 니켈/칼슘 하이드록시 아파타이트 촉매 상의 부탄 부분산화 연구
곽정훈(Kwak, Jung-Hun),이상엽(Lee, Sang-Yup),김미소(Kim, Mi-So),남석우(Nam, Suk-Woo),임태훈(Lim, Tae-Hoon),홍성안(Hong, Seong-Ahn),윤기준(Yoon, Ki-June) 한국신재생에너지학회 2007 한국신재생에너지학회 학술대회논문집 Vol.2007 No.11
Partail oxidation(POX) of n-butane was investigated in this research by employing ceria-promoted Ni/calcium hydroxyapatite catalysts (Ce_xNi_{2.5}Ca_{10}(OH)₂(PO₄)<sub>6</sub> ; x = 0.1{sim}0.3) which had recently been reported to exhibit good catalytic performance in POX of methane and propane. The experiments were carried out with changing ceria content, O₂/n-C₄H_{10} ratio and temperature. As the O₂/n-C₄H_{10} feed ratio increased up to 2.75, n-C₄H_{10} conversion and H₂ yield increased and the selectivity of methane and other hydrocarbons decreased. But with O₂/n-C₄H_{10} = 3.0, n-C₄H_{10} conversion and H₂ yield decreased. This is considered due to that too much oxygen may inhibit the reduction of Ni or induce the oxidation of Ni, which results in poor catalytic activity. The optimum O₂/n-C₄H_{10} ratio lay between 2.50 and 2.75. Ce_{0.1}Ni_{2.5}Ca_{10}(OH)₂(PO₄)<sub>6</sub> showed the highest n-C₄H_{10} conversion and H-2 yield on the whole. In durability tests, higher hydrogen yield and better catalyst stability were obtained with the O₂/n-C₄H_{10} ratio of 2.75 than with the ratio of 2.5.
( Charmaine A. Cabiscuelas ),( Lan Ying Li ),( Ki Eun Seon ),( Yup Kim ),( Jae Hoon Lee ),( Eun Ji Nam ),( Jung-yun Lee ),( Sunghoon Kim ),( Young Tae Kim ),( Sang Wun Kim ) 대한폐경학회 2021 대한폐경학회지 Vol.27 No.3
Objectives: This study compared serum anti-Mullerian hormone (AMH) levels in endometriotic cysts (ECs) with those in non-ECs and analyzed changes thereof after single-port laparoscopic (SPL) ovarian cyst enucleation using vasopressin injection. Methods: In total, 180 patients (EC group, n = 112; non-EC group, n = 68) who underwent SPL ovarian cyst enucleation were retrospectively reviewed. Their AMH levels were checked preoperatively, on postoperative day 10 (POD10), and on postoperative month 3 (POM3). Changes in AMH levels were analyzed according to tumor type and vasopressin use. Results: The median initial and postoperative serum AMH levels in the EC group were significantly lower than those in the non- EC group (preoperation: 2.0 vs 3.8 ng/mL, P < 0.001; POD10: 1.0 vs 3.2 ng/mL, P < 0.001; POM3: 1.2 vs 3.6 ng/mL, P < 0.001). The postoperative decrease in AMH levels was higher in the EC group than the non-EC group on POD10 (0.8 vs 0.5 ng/mL, P = 0.011) but not on POM3 (0.7 vs 0.5 ng/mL, P = 0.164). Vasopressin injection during EC enucleation had no significant effect on the decrease in AMH levels on POD10 (vasopressin group vs non-vasopressin group: 1.0 vs 0.8 ng/mL, P = 0.253) and POM3 (vasopressin group vs nonvasopressin group: 1.4 vs 1.1 ng/mL, P = 0.242). Conclusions: AMH levels were lower at baseline and had higher decreasing rates after SPL surgery in the EC group relative to the non- EC group. Vasopressin injection might not protect the ovary from the postoperative decrease in AMH levels.