박새지상부의 약효성분

정민영,황완균,김일혁 중앙대학교 약학연구소 1996 약학 논총 Vol.10 No.-

The pharmaco-constituents of the aerial part of Veratrum grandiflorum, of which roots and rhizomes have been used for the treatment of scabies, pimple, dandruff etc. in Korean folk remedies, and used as emetics, antituberculosis drugs, and antihypertensive drugs in Oriental Medicines were studied phytochemically. From H_2O fraction of MeOH extract, a flavone glycoside and a free flavone were isolated and elucidated as luteolin-7-O-β-D-glucuronopyranoside and luteolin through their physico-chemical data and UV, IR, EI-MS, FAB-MS, GC, ^13C-NMR, and ^1H-NMR analysis with authentics respectively.

윤상 다륜형 아급성 피부 홍반성 루푸스 1예

강민정,박혜진,조소연,이미애,황규광,함정희 대한피부과학회 1999 대한피부과학회지 Vol.37 No.6

We report an annular type of subacute cutaneous lupus erythematosus(SCLE) which is rare in Korea, A 23-year-old female had erythematous annular rashes with a mild itching sensation on the face, trunk and both extremities. She also had painless oral mucosal ulceration, diffuse hair loss and mild arthralgia. Serologic abnormalities of the patient were positive anti-Ro Ab, ANA and Anti-ds-DNA Ab. The histopathologic findings showed vacuolar degenerations in the basal cell layer, mononuclear cell infiltrate in the upper dermis, and dermal edema. Direct IF revealed granular deposition of IgG and IgA at the dermo-epidennal junction.

수정체의 노화에 따른 단백성분의 산화 : 수정체의 Nucleoschlerosis에 따른 변화

최기오,정영도,양성렬,황태익,안봉한,이민화 한국노화학회 1991 한국노화학회지 Vol.1 No.1

최근 5년간 피부외과술로 치료받은 환자의 분석 : 1994. 1∼1998. 12

신정현,강민정,조소연,황규광,함정희 梨花女子大學校 醫科大學 醫科學硏究所 2000 EMJ (Ewha medical journal) Vol.23 No.2

연구 목적 : 1990년대 이후 국외 및 국내에서 피부외과의 영역이 넓어지고 있으나 현재 국내에서 시행되고 있는 피부외과적 수술에 대한 통계는 아직 보고되지 않아 그 현황이 잘 파악되지 않고 있다. 이에 저자들은 본교실 미용피부외과 클리닉에 내원하여 수술을 받은 환자 1,075명을 대상으로 통계적 분석을 시행하여 피부외과 환자의 분포, 경향을 파악하여 향후 발전의 토대로 삼고자 한다. 방법: 1994년 1월부터 1998년 12월까지 5년간 이화여자대학교 의과대학 부속 동대문병원 피부과 미용피부외과 클리닉에 내원하여 수술을 받은 환자 1,075명을 대상으로 성별, 연령별, 주거지역별 분포와 진단명 및 수술의 종류에 대하여 통계적 분석하였다. 결과: 1) 남녀비는 1 : 2.4였고, 연령은 10개월부터 87세까지로 다양하였으나 20, 30대가 66.0%로 가장 많고 평균연령은 남자 30.6세, 여자 30.2세였다. 환자의 주거지역별 분포는 서울시가 75%로 가장 많았고 서울시내 지역구별의 차이는 크지 않았다. 2) 환자 1명이 두 가지 이상의 질환을 가질 때 각 질환을 개개로 간주하여 총 1.354예의 질환을 수술하였으며 반흔(39.8%), 색소성 질환(30.8%), 악성/양성종양(21.2%), 기타질환(8.2%) 순이었다. 3) 수술은 총 2,334회 시행되었고 그 종류별 빈도는 화학박피수술 가장 많아 846예(36.2%)이었고 다음으로 냉동외과술 650예(27.8%), CO_2 레이저 255예(10.9%), 기계박피술 209예(8.9%), 외과적 절제술 113예(4.8%), Mohs 미세도식수술 61예(2.6%), 혈관응고술 50예(2.1%), 피판재건술 48예(2.0%)이었으며 그 외 모발이식 15예, 표피이식 13예, 자가지방이식 2예 등이 있었다. 4) 각 반흔의 종류에 따라 분류하면, 여드름반흔은 화학박피술(72.7%), CO_2 레이저(11.9%) 및 기계박피술(9.7%)로, 위축성반흔은 기계박피술(37.3%). CO_2 레이저(27.8%) 및 펀치상향술(11.9%)로, 비후성반흔은 냉동외과술(28.2%), 기계박피술(24.2%) 및 CO_2 레이저(22.7%)로 치료하였다. 5) 악성종양 및 일부 양성종양에 Mohs 미세도식수술을 시행하였으며 재건술로 총 61예 중 피판재건술을 시행한 예가 가장 많아 45.9%이었고, 단순봉합이 36.1%, 복합봉합은 18.0% 이었다. 결론: 피부외과적 수술환자는 여자가 남자보다 2.4배 많았으나 남자의 비율이 증가추세에 있고 남녀 모두 평균 연령은 30대였다. 수술질환은 반흔과 색소성 질환이 가장 많아 미용적인 관심이 매우 높음을 알 수 있었고 연도별 유의한 차이는 없었다 총 2,334회 수술 중 화학박피술, 냉동외과술이 50% 이상을 차지하였고 반흔의 종류에 따라 선호되는 수술이 달랐다. 악성종양은 모두 Mohs 미세도식 수술하였으며 주로 국소 피판술로 재건하였다. 이상의 분석으로 피부외과적 수술환자의 분포, 대상질환, 수술방법 등을 빈도별로 파악할 수 있었으며, 향후 각 질환별 혹은 수술별로 세분하여 수술성과 및 만족도 조사를 시행함으로써 피부외과 분야 및 본 크리닉의 발전 방향을 설정하는 가늠자 역할을 할 것으로 기대한다. Background : The field of dermatologic surgery has seen trementdous developments in the past few years. Objective : Our purpose was to discuss current statistical data on the dermatologic patients treated by surgical methods at our institute. Methods : We analyzed 2,334 cases of surgeries performed on 1,075 patients at the Department of Dermatology of Ewha Womans University Tongdaemun Hospital during a period of 5 years (1994. 1 - 1998. 12). Results & Conclusion : The results are summarized as folows: 1) Of the 2,334 cases of surgeries, 846 cases(36.2%) were chemical peelings, 650 cases(27.8%) cryosurgeries, 255 cases(10.9%) CO_2, lasers, 209 cases(8.9%) dermabrasions, 113 cases(4.8%) scalpel surgeries, 61 cases(2.6%) Mohs micrographic surgeries, 50 cases(21.1%) sclerotherapy, 48 cases(2.0%) flap repair surgeries, 35 cases(1.5%) punch elevations, 15 cases(0.6%) hair transplantations, 13 cases(0.5%) epidermal grafts, and 2 cases(0.1%) autologous fat/collagen transplantations. 2) The ratio of male to female was 1 : 2.4 and the mean age of patients was 30.3 years. 3) A total of 1,354 cases of diseases were managed surgically : among them, the most frequent disease was scar(39.8%), followed by pigmentary disorders(30.8%), and benign or malignant tumors(21.2%). 4) With respect to the types of scars, acne scar was treated most frequently by chemical peeling (72.7% of 580 cases), atrophic scar by dermabrasion(37.3% of 126 cases), and hypertrophic scar (including burn scars) by cryosurgery(35.3% of 85 cases).

Lutembacher 증후군 환자 증례 보고

김성범,서정주,곽철훈,김상민,이보라,민선경,황은구,김용인,조욱현,최석구 인제대학교 2008 仁濟醫學 Vol.29 No.-

Lutembacher's syndrome is rare combination of mitral stenosis (MS) and atrial septal defect (ASD). The hemodynamic interplay between the MS and ASD leads to wide variation of clinical presentation. Here we describe a 43-year-old female with Lutembacher's syndrome and tricuspid regurgitation with pulmonary hypertension, who underwent direct closure of ASD and tricuspid valvuloplasty successfully. We also reviewed other literatures in an effort to increase awareness of this condition.

Intragenomic Length Variation of the Ribosomal DNA Intergentic Spacer in a Malaris Vector, Anopheles Sinensis

Whang, In-Jung,Jung, Jongwoo,Park, Joong-Ki,Min, Gi-Sik,Kim, Won Korean Society of Molecular Biology 2002 Molecules and cells Vol.14 No.1

Fuzzy C-mean Clustering을 이용한 각성 분류에 관한 연구

이정년(Jung Nyun Lee),황민철(Min Cheol Whang),김종화(Jong Hwa Kim),김치중(Chi Jung Kim),안상민(Sang Min An),박재언(Jae Un Park),박상인(Sang In Park) 대한인간공학회 2010 대한인간공학회 학술대회논문집 Vol.2010 No.10

This study was to determine the level of arousal based on physiological signals. Procedures employed in this study were as follows: Twelve visual stimuli were presented to each participant. Seven subjects assessed what they felt about the stimuli on a 5-likert scale while measuring PPG (photoplethysmograph) and GSR (galvanic skin response) of them. Then, similar patterns were extracted from the physiological signals and clustered into 5 groups using a fuzzy c-mean clustering algorithm. Finally, the relationship between scores obtained from the subjective assessment and physiological patterns clustered by the fuzzy algorithm was examined to identify how exactly the two data were consistent. Of the five physiological patterns, one was almost exactly consistent with the subjective rating. However, remains of the categorized patterns showed inconsistent results. The results from this study are expected to be a starting point for evaluating humans’ emotion. In order to ensure reliability and validity, further study for enhancing the accuracy between the psychological and physiological assessment should be followed.

Development of Bioartificial Oral Buccal Mucosa Model using Human Amniotic Membrane Cultured Oral Mucosa Epithelial cells

Hee-Jung Park(박희정),Young-Kwon Seo(서영권),Jae-Il Ahn(안재일),Kang-Min Ahn(안강민),Jong-Ho Lee(이종호),Sun-Jung Whang(황순정),Eun-kyung Yang(양은경),Kye-Yong Song(송계용),Jung-Keug Park(박정극) 한국생물공학회 2004 한국생물공학회 학술대회 Vol.2004 No.10

외상성 동맥손상 환자의 임상양상 변화

정석인,황정웅,민연기,천영덕,조용걸 대한혈관외과학회 2001 Vascular Specialist International Vol.17 No.1

Purpose: As traffic accidents and invasive vascular procedures are increasing these days so are vascular trauma, either blunt or penetrating. So we investigated the changes of clinical status of vascular trauma for the last 10 years. Method: We retrospectively reviewed the medical records of 121 patients who had admitted and operated at Korea University Hospital due to traumatic arterial injuries from 1990 to 1999. We divided those patients by period into two groups; Era 1 (1990~1994) and Era 2 (1995~1999). The former group included 51 patients, the latter 70. Age distribution, causes of injury, location, degrees of injury, amputation rate, mortality rate, and operation methods between these two groups were compared. Result: The most common cause of arterial injury was blunt trauma by traffic accident in Era 1, injury by broken glasses in Era 2. Iatrogenic injury cases increased (from 3.9% in Era 1 to 10% in Era 2), and so did industrial injuries. Two groups also show similar distribution of degrees and location of injuries. Amputation rate in cases of vascular trauma of lower extremities correlates with combined fracture in both group (p$lt;0.05). Amputation rate was 35.5% in Era 1, and 23.5% in Era 2. The mortality rate was 15.7% in Era 1 and 12.9% in Era 2 (p$gt;0.05). Each group presented statistically significant correlation between location of injury and mortality (p$lt;0.05). Abdominal injury was related to high mortality rate (63.2%). Conclusion: The latter period (Era 2) showed increased iatrogenic injury rate compared to the former. Amputation rate increased when combined with fracture in both groups, but mortality rate didn't significantly change between these two groups.

Enhanced Light Stability of InGaZnO Thin-Film Transistors by Atomic-Layer-Deposited Y₂O₃ with Ozone

Jung, Hanearl,Kim, Woo-Hee,Park, Bo-Eun,Woo, Whang Je,Oh, Il-Kwon,Lee, Su Jeong,Kim, Yun Cheol,Myoung, Jae-Min,Gatineau, Satoko,Dussarrat, Christian,Kim, Hyungjun American Chemical Society 2018 ACS APPLIED MATERIALS & INTERFACES Vol.10 No.2

<P>We report the effect of Y2O3 passivation by atomic layer deposition (ALD) using various oxidants, such as H2O, O-2 plasma, and O-3, on In-Ga-Zn-O thin-film transistors (IGZO TFTs). A large negative shift in the threshold voltage (V-th) was observed in the case of the TFT subjected to the H2O-ALD Y2O3 process; this shift was caused by a donor effect of negatively charged chemisorbed H2O molecules. In addition, degradation of the IGZO TFT device performance after the O-2 plasma-ALD Y2O3 process (field-effect mobility (mu) = 8.7 cm(2)/(V.s), subthreshold swing (SS) = 0.77 V/dec, and V-th = 3.7 V) was observed, which was attributed to plasma damage on the IGZO surface adversely affecting the stability of the TFT under light illumination. In contrast, the O-3-ALD Y2O3 process led to enhanced device stability under light illumination (Delta V-th = 1 V after 3 h of illumination) by passivating the subgap defect states in the IGZO surface region. In addition, TFTs with a thicker IGZO film (55 nm, which was the optimum thickness under the current investigation) showed more stable device performance than TFTs with a thinner IGZO film (30 nm) (Delta V-th = -0.4 V after 3 h of light illumination) by triggering the recombination of holes diffusing from the IGZO surface to the insulator-channel interface. Therefore, we envisioned that the O-3-ALD Y2O3 passivation layer suggested in this paper can improve the photostability of TFTs under light illumination.</P>