Digitalis中毒症과 豫防

崔碩求 藥業新聞社 1985 (月刊) 醫藥情報 Vol.1985 No.11

혈압 측정에 있어, 측정자 내의 그리고 측정자 간의 오차

최석구 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

Objectives : There are many factors which can give influences on the measurement of blood pressure. I could collect very precious data in process of training the members of the special team who would measure blood pressure in the National Health and Nutrition Survey and find very interesting results about the intra-individual and inter-individual errors in measuring blood pressure. Methods and Materials : Forty two registered nurses were recruited. They were all healthy women. After the lectures about the principles in measuring blood pressure, they were divided into 14 small groups, that is, 3 women in a group. In a small group, they measured blood pressure of other members 2 times for each one, according to the standardized methods and procedures. After all measurements were finished, they changed the partners, formed new groups and measured blood pressure the same way. Each of them had the opportunites to measure blood pressure 12 times and to be measured 12 times during 3 sessions. These data were analized. Results : Twenty-six(62%) of 42 trainees in the first and second sessions and 40(100%) of 40 trainees in the third session followed the standardized methods and procedures. 21(81%) of 26 trainees in the first and second sessions and 34(85%) of 40 trainees in the third session showed the intra-individual difference within 4㎜Hg. 11(41%) of 27 pairs of the measured values in the first and second sessions and 17(61%) of the 28 pairs in the third session showed the difference within 4㎜Hg as the inter-individual errors. 14(93%) of 15 trainees in the first and second sessions and 6(86%) of 7 trainees in the third session showed the difference within 4㎜Hg, as compared with the standard nurse. Conclusion : It could be suggested that preciser and more reliable blood pressure could be measured when the standardized methods and procedures were thoroughly followed step by step. The establishment and implement of our own standard methods and procedures are strongly requested.

가정의학 : 고혈압 환자의 겨울나기

최석구 대한보건협회 2006 건강생활 Vol.- No.54

VLSI화를 위한 MOSFET-C 필터 설계 ( MOSFET-C Filter Design for VLSI )

최석구,조성익,김동용,윤창훈,권오신 대한전자공학회 1988 대한전자공학회 학술대회 Vol.1988 No.1

고혈압 치료의 전망

최석구 약업신문사 1996 의약정보 Vol.1996 No.6

Gentamicin 제제의 약력학적 비교

최석구,신상구,박찬웅 대한화학요법학회 1984 대한화학요법학회지 Vol.2 No.2

The pharnacokinetic characteristics of 3 different gentamicin formulations, supplied from 3 different producers in Korea, were studied in 15 healthy male volunteers after a single intramuscular injection with a dose of 80mg. Serial serum drug lerels were analysed using a one compartmental open model. Serum gentamicin levels of "C" formulation were higher than those of other formulations. Pharmacokinetic parameters such as absorption rate constant, elimination rate constant and serum half-life for 3 formulations, were nearly identical. Bct areas under the curves(AUC's) for 3 formulations showed significant differences among them. Relati\-e avaiiahilities of "A" and "B" formulation to "C" formulation were 0. 67 and 0.44, respectively. So, it was considered that the differences in serum drug levels after an intram- uscular injection of gentamicin from 3 different producers might be due t o the differences in formulations or manufacturing processes.

강압제의 병용 요법

최석구 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.4

Combination therapy in hypertension was mentioned and recommended in the worldwide known reports. It has many advantages, such as enhancing efficacy, toler-ability, compliance and salutary effects on target organs. There are many pairs of antihypertensive drugs, which advantages were proven. Also fixed dose combination drugs are available. Combination therapy could meet the most of prerequisites for idea antihypertensive drugs, such as efficacy, safety, impact on the quality of lift, compliance, ease of administration, and cost.

급성 심근경색증의 조기진단을 위한 혈청 마이오글로빈 측정의 진단적 가치

최석구,성영주,이건주,유원상,박성섭 인제대학교 1992 仁濟醫學 Vol.13 No.3

흉통 발생 이후 6시간 이내에 응급실로 내원한, 급성 심근경색증이 의심되는 환자들에서, 이의 확진을 위한 보조 진단방법으로 latex 응집을 이용한 혈청 마이오글로빈 측정의 유용성을 검토하였다. Since intravenous thrombolytic therapy was established as a standard therapy in the management of acute myocardial infarction(AMI), an early diagnosis of AMI call more attention than ever. We examined the diagnostic usefulness of the serum myoglobin using latex agglutination(Rapi TexR Myoglobin ; Beringer, Germany) as an emergency screening test which took less than 5 minutes to obtain the results. Twenty three patients with AMI and 6 subjects without AMI as controls were studied. All the patients arrived at the emergency room within 6 hours from the onset of chest pain. Fifteen out of 23 patients and 3 out of 6 controls were positive ; 8 out of 23 patients and 3 out of 6 controls negative. The sensitivity of the assay was 74% and specificity 27%. The predictive value of the positive response was 83% and the predictive value of the negative response 27%. We concluded that the serum myoglobin assay using latex agglutination was useful as an emergency screening test for the early diagnosis of AMI. It was easy to handle, quick to get the results and reliable as an emergency screening test.

심부전환자의 관리대책

최석구 한국만성질환관리협회 1993 월간성인병 Vol.147 No.-

방산 중소기업의 지속적 개선활동이 공급망 품질경영활동과 기업성과에 미치는 영향에 관한 연구

최석구,이태화,유한주,송광석 한국품질경영학회 2020 품질경영학회지 Vol.48 No.1

Purpose: This study analyzes the characteristics of the Quality Management performed by SMEs in the Defense Industry in supply chains and analyzes the effect of the continuous improvement activities based on cooperation. Especially, for Military Supplies, the suitability of products is usually decided by judging their conformity to the specification, and from this structural characteristic, this study would analyze the structural relationship of systematic improvement activities with Supply Chain Quality Management(SCQM) and Business Performance(BP). Methods: Continuous improvement activities(CI) have significance as the driver force for the promotion of Quality Management. Thus, this study analyzed the causal relationships from the perspective of the process among CI, SCQM and BP. For an analysis of the structural characteristics and causal relationships among the constituents, AMOS was used, and 297 companies in the Defense Industry were utilized as samples. Results: It turned out that CI had significant impacts on Management Infra(MGT_Infra), Process Management(PM), Human Resources Management(HRM) and Communication(COMU) and had an indirect impact on the enterprises’ financial performance through the parameters of HRM and Communication. Meanwhile, it turned out that between CI and non-financial performance, there was a direct effect, and there was also an indirect effect through the variables of the Management Infra and Communication. Conclusion: It turned out that CI had a positive effect on SCQM as a proactive driver and that they had significant relationships with BP(financial, Non-financial), both financial performance and non-financial performance. However, PM did not have a significant relationship of effect with BP because of the character appearing by the evaluation method of military supplies for the conformity to the specifications.