칼슘처리와 MA포장이 딸기의 품질에 미치는 영향

( Jun Feng Guan ),박형우 ( Hyung Woo Park ),김윤호 ( Yoon Ho Kim ),김상희 ( Sang Hee Kim ),박혜란 ( Hye Ran Park ) 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2006 한국식품저장유통학회지 Vol.13 No.1

The Effect of Functional MA Film Packaging on Storage of Mature-Red Tomato

Jun Feng Guan,Hyung Woo Park,Yoon Ho Kim,Sang Hee Kim,Hye Ran Park,Seon Ah Lee,Ji Yoon Yoon 한국포장학회 2005 한국포장학회지 Vol.11 No.2

토마토(Pinky 종)를 기능성 MA필름(두께 0.03, 0.06mm)으로 포장하여 0, 5, 15℃에 저장하면서 품질 변화를 조사하였다. 저장 29일에 MA포장재 내의 CO2, O2농도는 각각 4.21~8.17%, 9.78~14.45%였고, 전반적으로 MA 포장구에서 연화와 색택의 변화가 억제되었다. 저장 29일에 MA포장(0.03두께)을 한 후 5℃에 저장한 토마토의 경도(0.49 kgf)가 가장 높았고, MA 포장(0.06두께)을 한 후 0℃에 저장한 토마토가 최소 라이코펜 함량(6.08mg/100g)을 보였다. 토마토의 품질 유지를 위한 최적 조건은 MA 장을 하여 0℃에 저장하는 것이 바람직한 것으로 나타났으며 필름 두께간에는 유의적인 차이가 나타나지 않았다. 또한 MA 포장재 내의 최적 가스 조성은 CO2는 4.2%~5.6%, O2는 14.3%~14.5%로 나타났다. The mature-red tomato fruits (cv. Pinky world) were packaged with functional modified atmosphere (MA) film (0.03, 0.06 mm) and stored at 0, 5, 15℃. The results showed that the concentrations of CO2 and O2 inside MA package were about 4.21~8.17% and 9.78~14.45% under steady state during storage 29 days at 0, 5℃, respectively. The MA packaging(MAP) suppressed the fruits softening and the color change. The minimum lycopene content and maximum firmness were separately observed in fruits packaged with MA film (0.03 mm) at 5℃ storage and film(0.06 mm) at 0℃, which the lycopene content 6.08 mg/100 g, and firmness was 0.49 Kgf at 29 th day storage. The optimal conditions to keep high quality of tomato fruits were obtained by MAP during storage at 0℃ for 29 days, independently of the film thickness, in which the adequate gas composition was CO2 at 4.2%~5.6%, O2 at 14.3%~14.5%, respectively.

The prognostic significance of estrogen and progesterone receptors in grade I and II endometrioid endometrial adenocarcinoma: hormone receptors in risk stratification

Jun Guan,Liying Xie,Xuezhen Luo,Bingyi Yang,Hongwei Zhang,Qin Zhu,Xiaojun Chen 대한부인종양학회 2019 Journal of Gynecologic Oncology Vol.30 No.1

Objectives: Although patients with grade I and II endometrioid endometrial adenocarcinoma (EEA) are considered with good prognosis, among them 15%–25% died in 5 years. It is still unknown whether integrating estrogen receptor (ER) and progesterone receptor (PR) into clinical risk stratification can help select high-risk patients with grade I–II EEA. This study was to investigate the prognostic value of ER and PR double negativity (ER/ PR loss) in grade I–II EEA, and the association between ER/PR loss and The Cancer Genome Atlas (TCGA) classification. Methods: ER and PR were assessed by immunohistochemistry on hysterectomy specimens of 903 patients with grade I–II EEA. ER and PR negativity were determined when <1% tumor nuclei were stained. Gene expression data were obtained from the TCGA research network. Results: Compared with ER or PR positive patients (n=868), patients with ER/PR loss (n=35) had deeper myometrial infiltration (p=0.012), severer FIGO stage (p=0.004), and higher rate of pelvic lymph node metastasis (p=0.020). In univariate analysis, ER/PR loss correlated with a shorter progression-free survival (PFS; hazard ratio [HR]=5.25; 95% confidence interval [CI]=2.21–12.52) and overall survival (OS; HR=7.59; 95% CI=2.55–22.60). In multivariate analysis, ER/PR loss independently predicted poor PFS (HR=3.77; 95% CI=1.60–10.14) and OS (HR=5.56; 95% CI=1.37–22.55) for all patients, and poor PFS for patients in stage IA (n=695; HR=5.54; 95% CI=1.28–23.89) and stage II–IV (n=129; HR=5.77; 95% CI=1.57–21.27). No association was found between ER/PR loss and TCGA classification. Conclusion: Integrating ER/PR evaluation into clinical risk stratification may improve prognosis for grade I–II EEA patients.

Sentinel lymph Node mapping versus systematic pelvic lymphadenectomy on the prognosis for patients with intermediate-high-risk Endometrial Cancer confined to the uterus before surgery: trial protocol for a non-inferiority randomized controlled trial (SNE

Jun Guan,Yu Xue,Rong-yu Zang,Ji-hong Liu,Jian-qing Zhu,Ying Zheng,Bo Wang,Hua-ying Wang,Xiao-jun Chen 대한부인종양학회 2021 Journal of Gynecologic Oncology Vol.32 No.4

Background: Sentinel lymph node (SLN) mapping has been recommended as an alternative staging approach to lymphadenectomy for apparent uterine-confined endometrial cancer (EC). However, the prognostic value of SLN mapping alone instead of systematic lymphadenectomy on EC patients remains unclear. Methods: A multi-center, open label, non-inferiority randomized controlled trial has been designed to identify if SLN mapping alone is not inferior to pelvic lymphadenectomy on prognosis of patients with intermediate-high-risk EC clinically confined to uterus. Eligible patients will be 1:1 randomly assigned to accept SLN mapping or pelvic lymphadenectomy. The primary endpoint is the 2-year progression-free survival (PFS). The second points are the 5-year PFS, 5-year overall survival, surgery-related adverse events and life quality. A total of 780 patients will be enrolled from 6 hospitals in China within 3-year period and followed up for 5 years. Trial Registration: ClinicalTrials.gov Identifier: NCT04276532

The Effect of Functional MA Film Packaging on Storage of Mature-Red Tomato

Guan, Jun-Feng,Park, Hyung-Woo,Kim, Yoon-Ho,Kim, Sang-Hee,Park, Hye-Ran,Lee, Seon-Ah,Yoon, Ji-Yoon Korea Society of Packaging Science and Technology 2005 한국포장학회지 Vol.11 No.2

토마토(Pinky 종)를 기능성 MA필름(두께 0.03, 0.06mm)으로 포장하여 0, 5, $15^{\circ}C$에 저장하면서 품질 변화를 조사하였다. 저장 29일에 MA포장재 내의 $CO_2$, $O_2$농도는 각각 $4.21{\sim}8.17%$, $9.78{\sim}14.45%$였고, 전반적으로 MA 포장구에서 연화와 색택의 변화가 억제되었다. 저장 29일에 MA포장(0.03두께)을 한 후 $5^{\circ}C$에 저장한 토마토의 경도(0.49 kgf)가 가장 높았고, MA 포장(0.06두께)을 한 후 $0^{\circ}C$에 저장한 토마토가 최소 라이코펜 함량(6.08mg/100g)을 보였다. 토마토의 품질 유지를 위한 최적 조건은 MA 장을 하여 $0^{\circ}C$에 저장하는 것이 바람직한 것으로 나타났으며 필름 두께간에는 유의적인 차이가 나타나지 않았다. 또한 MA 포장재 내의 최적 가스 조성은 $CO_2$는 $4.2%{\sim}5.6%$, $O_2$는 $14.3%{\sim}14.5%$로 나타났다. The mature-red tomato fruits (cv. Pinky world) were packaged with functional modified atmosphere (MA) film (0.03, 0.06 mm) and stored at 0, 5, $15^{\circ}C$. The results showed that the concentrations of $CO_2$ and $O_2$ inside MA package were about $4.21{\sim}8.17%$ and $9.78{\sim}14.45%$ under steady state during storage 29 days at 0, $5^{\circ}C$, respectively. The MA packaging(MAP) suppressed the fruits softening and the color change. The minimum lycopene content and maximum firmness were separately observed in fruits packaged with MA film (0.03 mm) at $5^{\circ}C$ storage and film(0.06 mm) at $0^{\circ}C$, which the lycopene content 6.08 mg/100 g, and firmness was 0.49 Kgf at 29 th day storage. The optimal conditions to keep high quality of tomato fruits were obtained by MAP during storage at $0^{\circ}C$ for 29 days, independently of the film thickness, in which the adequate gas composition was $CO_2$ at $4.2%{\sim}5.6%$, $O_2$ at $14.3%{\sim}14.5%$, respectively.

Soliton Transmission Experiment Employing Normal Dispersion Fiber with Large Dispersion

Jian Jun Yu,Ke Jian Guan,Bo Jun Yang 한국통신학회 1997 OPTOELECTRONICS & COMMUNICATIONS CONFERENCE Vol.2 No.1

Effect of Insulin-like Growth Factor-1 on Bone Morphogenetic Protein-2 Expression in Hepatic Carcinoma SMMC7721 Cells through the p38 MAPK Signaling Pathway

Xu, Guan-Jun,Cai, Sheng,Wu, Jian-Bing Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

Objective: To observe the effect of insulin-like growth factor-1 (IGF-1) on bone morphogenetic protein (BMP)-2 expression in hepatocellular carcinoma SMMC7721 cells. Methods: Cells were divided into blank control, IGF-1, IGF-1 + SB203580, and SB203580 groups. SB203580 was used to block the p38 MAPK signaling pathway. Changes in the expression of BMP-2, p38 MAPK, and phosphorylated p38, MERK, ERK and JNK were determined using reverse transcription polymerase chain reactions (RT-PCR) and Western blot analysis. Results: Protein expression of phosphorylated BMP-2, MERK, ERK, and JNK was significantly up-regulated by IGF-1 compared with the control group ($1.138{\pm}0.065$ vs. $0.606{\pm}0.013$, $0.292{\pm}0.005$ vs. $0.150{\pm}0.081$, $0.378{\pm}0.006$ vs. $0.606{\pm}0.013$, and $0.299{\pm}0.015$ vs. $0.196{\pm}0.017$, respectively; P<0.05). Levels of BMP-2 and phosphorylated MERK and JNK were significantly reduced after blocking of the p38MAPK signaling pathway ($0.494{\pm}0.052$ vs. $0.165{\pm}0.017$, $0.073{\pm}0.07$ vs. $0.150{\pm}0.081$, and $0.018{\pm}0.008$ vs. $0.196{\pm}0.017$, respectively; P<0.05), but such a significant difference was not observed for phosphorylated ERK protein expression ($0.173{\pm}0.07$ vs. $0.150{\pm}0.081$, P>0.05). Conclusion: IGF-1 can up-regulate BMP-2 expression, and p38 MAPK signaling pathway blockage can noticeably reduce the up-regulated expression. We can conclude that the up-regulatory effect of IGF-1 on BMP-2 expression is realized through the p38 MAPK signaling pathway.

Reports ; Adrenergic receptor β2 activation by stress promotes breast cancer progression through macrophages M2 polarization in tumor microenvironment

( Jun-fang Qin ),( Feng-jiao Jin ),( Ning Li ),( Hai-tao Guan ),( Lan Lan ),( Hong Ni ),( Yue Wang ) 생화학분자생물학회 2015 BMB Reports Vol.48 No.5

Stress and its related hormones epinephrine (E) and norepinephrine (NE) play a crucial role in tumor progression. Macrophages in the tumor microenvironment (TME) polarized to M2 is also a vital pathway for tumor deterioration. Here, we explore the underlying role of macrophages in the effect of stress and E promoting breast cancer growth. It was found that the weight and volume of tumor in tumor bearing mice were increased, and dramatically accompanied with the rising E level after chronic stress using social isolation. What is most noteworthy, the number of M2 macrophages inside tumor was up-regulated with it. The effects of E treatment appear to be directly related to the change of M2 phenotype is reproduced in vitro. Moreover, E receptor ADRβ2 involved in E promoting M2 polarization was comprehended simultaneously. Our results imply psychological stress is influential on specific immune system, more essential for the comprehensive treatment against tumors. [BMB Reports 2015; 48(5): 295-300]

An Improved Fast Camera Calibration Method for Mobile Terminals

Guan, Fang-li,Xu, Ai-jun,Jiang, Guang-yu Korea Information Processing Society 2019 Journal of information processing systems Vol.15 No.5

Camera calibration is an important part of machine vision and close-range photogrammetry. Since current calibration methods fail to obtain ideal internal and external camera parameters with limited computing resources on mobile terminals efficiently, this paper proposes an improved fast camera calibration method for mobile terminals. Based on traditional camera calibration method, the new method introduces two-order radial distortion and tangential distortion models to establish the camera model with nonlinear distortion items. Meanwhile, the nonlinear least square L-M algorithm is used to optimize parameters iteration, the new method can quickly obtain high-precise internal and external camera parameters. The experimental results show that the new method improves the efficiency and precision of camera calibration. Terminals simulation experiment on PC indicates that the time consuming of parameter iteration reduced from 0.220 seconds to 0.063 seconds (0.234 seconds on mobile terminals) and the average reprojection error reduced from 0.25 pixel to 0.15 pixel. Therefore, the new method is an ideal mobile terminals camera calibration method which can expand the application range of 3D reconstruction and close-range photogrammetry technology on mobile terminals.

Improved Conditional Differential Attacks on Round-Reduced Grain v1

( Jun-zhi Li ),( Jie Guan ) 한국인터넷정보학회 2018 KSII Transactions on Internet and Information Syst Vol.12 No.9

Conditional differential attack against NFSR-based cryptosystems proposed by Knellwolf et al. in Asiacrypt 2010 has been widely used for analyzing round-reduced Grain v1. In this paper, we present improved conditional differential attacks on Grain v1 based on a factorization simplification method, which makes it possible to obtain the expressions of internal states in more rounds and analyze the expressions more precisely. Following a condition-imposing strategy that saves more IV bits, Sarkar’s distinguishing attack on Grain v1 of 106 rounds is improved to a key recovery attack. Moreover, we show new distinguishing attack and key recovery attack on Grain v1 of 107 rounds with lower complexity O(2³⁴) and appreciable theoretical success probability 93.7%. Most importantly, our attacks can practically recover key expressions with higher success probability than theoretical results.