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전진용,오동열,구민성,이준석,천근아,박웅섭,김상아 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.4
Objectives : This study was designed to assess the relationship between alcohol use and stress. Methods : The study subjects were 1,261 people who drink among the 2,565 people who lived in Gangneung. We investigated the sociodemographic characteristics, Short Form-12 (SF-12), Global Assessment of Recent Stress (GARS) and Alcohol Use Disorder Identification Test (AUDIT). Results : In Problem drinking group the GARS was significantly positively associated with the AUDIT (p=0.02). In Social drinking group sex (p<0.001) and age (p=0.02) is significantly associated with the AUDIT. Conclusion : This study showed the significantly positively association between stress and alcohol use. We think that the intervention and active management of the stress can prevent the alcohol problem.
태권도 지도자들의 지도자 연수 프로그램 인식도에 관한 연구
오대영,박준석,진중의 龍仁大學校 武道硏究所 1997 武道硏究所誌 Vol.8 No.2
In this assertation I tried to investigate the disposition of what the Taekwondo masters think of the training programes for the Taekwondo masters and then tried also to study the direction of its advancement. The conclusions I obtained through the assertations are like the followings. First, for the most important reasons, the Taekwondo masters attend such training programes because it is necessary(40.9%), second for the development of himself(30.3%), third to help the educations on the next generation(26.8%). Second, they are satisfied with the facilities of training institute(56.1%) 26.8% feel inconvinient. Third, those who lecture in the training programes are sincere and feel that the training programes are helpful in the knowledge and skills. Forth, the exercise programes are the most helpful ones among all the training programes and the masters prefer the programes that are useful in actual situations. Thus, we can conclude that the current training programes are necessary for the trained, and it is required to found more facilities and various programes based on the enough investment.
이중혈류유발 심폐소생술이 심정지를 유발한 개의 단기 생존율에 미치는 영향
황성오,조준휘,강구현,김성환,문중범,이강현,이승환,윤정한,최경훈,홍은석 대한응급의학회 2000 대한응급의학회지 Vol.11 No.3
Background and Objectives: We previously reported that, compared with standard cardiopulmonary resuscitation(S-CPR), better hemodynamic effects could be achieved by simultaneous sterno-thoracic cardiopulmonary resuscitation(SST-CPR) in which we compressed the sternum and constricted the thorax circumferentially during the systolic period by using a device. This study was designed to assess whether SST-CPR, compared with S-CPR, improve the survival rate of dogs with cardiac arrest. Subjects and methods: Twenty-five mongrel dogs(19∼31㎏) were enrolled in this study. After four minutes of ventricular fibrillation induced by an AC current, animals were randomized to resuscitate with either S-CPR(n=13) or SST-CPR(n=12). Epinephrine(1 ㎎) was injected into the right atrium every three minutes after the beginning of CPR. Defibrillation was attempted after 6 minutes of CPR. Standard advanced cardiac life support was started if defibrillation was not successful. Results: SST-CPR resulted in significantly(p<0.001) higher systolic arterial pressure(91±47 vs 47±24 ㎜ Hg), diastolic pressure(43±24 vs 17±10 ㎜ Hg), coronary perfusion pressure(35±25 vs 13±9㎜ Hg), and end tidal CO2 tension(9±4 vs 3±2 ㎜ Hg). Two of 13 animals(15 %) resuscitated with S-CPR and six of 12 animals(50%) resuscitated with SST-CPR survived until 12 hours after cardiac arrest(p<0.05). Donclusion: SST-CPR, compared with S-CPR, improves the short-term survival rate in canine cardiac arrest.
강태석,김종민,서경원,김영옥,김준규,오재호,이윤동,김규봉,오정자,송연정,임종준,전범석,문전옥,최광식 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-
MPTP 독성물질이 도파민성 신경세포에 선택적으로 작용하여 산화성 손상에 의한 신경세포사를 일으키는 것을 이용하여 파킨슨병의 동물모델을 만들고, 이를 통해서 아폼토시스를 비롯한 포사의 기전에 대한 연구 및 너코틴의 신경세포 보호효과 여부를 판정하는 실험을 병행하고자 하였다. 파킨슨꾐의 동물모델을 MPTf 독성 물질을 이용하여 확립하였으며, MPTP(30mgag, i.p.)를 투여한 후 1, 2,3, 4, 5일째 흑질 조직을 채춰하여 tarm로 박걸하여 tyrosine hydroxylase 면역조직화학염색을 수행하여 cell countif우한 결과, control은 57.635ce11s, 1일째 친.OfDells,2일째 57.9±6cells,3일릴 없.3±죠ells, 4일째 49.0츠3cells, 5일째 39.4±Scells료 4, 3일째 뚜렷한 신경세포 수의 감소를 보였다. 신경세포사 기전 규명을 위한 아폼토시스 분걱에서는 벼PTP 투여 후 1, 2, 3, 4, 5일째 조직을 채취하여 Hoechst staining, TUNEL staining을 수곡하였는데 양성 반응을 보인 신경세포는 관찰되지 않아. 아폼토시스로 인한 세포사가 관찰되지 않았다. bIPTP 파킨슨병 동물모델에서 nicotine 보호효과 탐색에 관한 실험은 nicat푸e 0.2mgAg을 5일 퐁안 투여 후 리『fP(30mgag)를 CS7Bt/6 마은스에 복강 내주사로 nicotine과 병용 투여한 후 1, 2, 3, 4, 5일째 뇌를 적출하땄다. 신경세포사가 뚜렷이 관찰되기 시작하는 4, 5일째의 신경세포 수의 감소 정도를 20. 30% 정도 약화시키는 경향을 보였으나, nicotine 보호효과에 대한 추가 실헝이 현재 수행 중에 있다. The cause of Parkinson's disease (PD) is largely unknown. However, free radical toxicit? may plaf a role ip. the degeneration of substantia nigra, which is the Hajorfocus of pathological damages in PD. Recently, a neuroprotective effect of nicotine in PD has been suggested. Therefore, the mechanism of neurodegenerafion and protective potential o( nicotine in PD were investigated in the experimental modeB of Pll using a neurotoxin, C57BL/6mice were administered with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP, 30 mg/kg,j.p.). The degree of neurodegenerafion was determined by immunohistochemical stainiHB oftyrosine hydroxylase (TH). TH-positive cells on nigral sections were found 56.0 ±4, 57.9 ±6,52.315ce11s, 49.0±3cells, and 39,4±Scells at days 1, 2, 3, 4, 5, respectively (controls : 57.6±Scells). Hoechst and TUNEL staining showed no evidence of apoptosis. The exandnation on themice co-adrunistered with nicotine(0.2mgAg) and MPTP(30mgag) revealed a tendency ofnicotine protective effects. At days 4 and 5, the degree of TH-positive cells was decreased by20-30%, In corclusiffn, the role of apoptosis was not evidenced in this MPTP modeB of PB.The possible proteccon by nicotine should be elucidated with further studies.
고성석,오준호 한국산업안전학회 2002 한국안전학회지 Vol.17 No.3
The object of risk assesment is to prevent the accident from arising. The main reason for risk assesment of construction work is to determine priority order of improvement plan about risky work. Formwork is a complicated process that determines the total duration of apartment construction, and occupies 10~15% of total construction expense, and 17% of serious accidents occur during formwork. So, formwork occupies very importment roles in work sites, economical efficiency and safety. We need to identify the work type with a high risk of accidents, and to establish suitable safety counterplan and implement intensive safety management.
주요우울증에서 우울과 불안 증상의 심각도에 따른 뇌파 A1,A2, Percent 비대칭 지표들의 특성 연구
이준석,양병환,오동열,김기성 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.2
Objectives : In this study we investigated characteristics of asymmetry pattern of EEG in patients with major depressive disor-der according to the severity of depression and anxiety symptoms, employing A1, A2, and Percent (PCT) asymmetry indices. Methods : Subjects involved in this study were 11 healthy controls and 11 patients with major depressive disorder who have taken no medicines for four weeks just before the study. These subjects were selected so that the two groups can have no difference in gender and age. Beck Depression Inventory (BDI), 17-item Hamilton Depression Rating Scale (HDRS), Zung's Self-Rating Depression Scale (SDS) and Spielberger's State-Trait Anxiety Inventory (STAI) were used to evaluate depression and anxiety symptoms, respectively. Resting EEG was recorded &om F3, F4, C3, C4, T7, T8, 01 and 02 electrode sites. Results : The temporal region showed a difference in A1, A2, and PCT asymmetry indices between the depression group and the control group. Frontal (F3, F4) and temporal (T7, T8) regions showed correlation between STAI-T score and A1, A2, and PCT asymmetry indices. Conclusion : The results of this study showed that EEG A1, A2, and PCT asymmetry indices can be used as useful indices for depression. Also, it was found that trait anxiety had influence on A1, A2, and PCT asymmetry indices.
김석준,권순정,오은진,김노석,김상길,이특구 한국의료복지시설학회 2008 의료·복지 건축 Vol.14 No.3
As the elderly population is growing rapidly, guidelines for planning and designing of the elderly housing are required for improving housing environment of the elderly. The purpose of this study is making the basic dimensional standardization of residential spaces for the elderly. The dimensional standard of spaces suggested in this guideline considers characteristics of both aged and the general users. The spaces studied in this research include bedroom, living room, bathroom, kitchen and other circulation spaces in the elderly housing. The design guidelines of furniture, equipment for the aged with sizing of the areas are provided. Finally, applicability of the output is reexamined by implementing this guidelines to the sample planning and design of the elderly housing