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정맥용 면역글로불린 투여 후 발생한 무균성 수막염 3례
이준호,송은경,이진아,김남희,김동호,박기원,최은화,이환종,Lee, Joon Ho,Song, Eun Kyoung,Lee, Jin A,Kim, Nam Hee,Kim, Dong Ho,Park, Ki Won,Choi, Eun Hwa,Lee, Hoan Jong 대한소아감염학회 2005 Pediatric Infection and Vaccine Vol.12 No.2
IVIG 투여에 의해 무균성 수막염은 그 기전이 밝혀지지 않았으나 IVIG 투여와 관련된 신경학적 부작용 중 가장 중한 합병증의 하나이다. 저자들은 서울대학교 어린이병원에서 2003년부터 2004년까지 3명의 환아에서 확인된 IVIG 투여와 관련된 무균성 수막염 4례를 경험하여 보고하였다. 3명의 환아는 ITP, 가와사키병, 중증 근무력증으로 기저질환은 각각 상이하였으나 기저질환에 대한 치료를 위해 모두 고용량의 IVIG를 투여받았으며, IVIG를 투여받은 후 1~2일 이내에 심한 두통과 뇌막자극 징후를 보였다. 척수액 소견상 백혈구 수는 $100/{\mu}L$ 미만에서부터 $1,000/{\mu}L$ 이상까지 다양하였으나 주로 다핵구로 구성된 척수액 백혈구 분포를 보였고(66~98%), 세균 배양검사와 장바이러스 배양과 PCR 검사에서 음성 결과를 보였다. 3명의 환아 모두 수막염 발생 2일 후까지는 증상이 호전되었으며, 후유증 및 장애가 없었다. Intravenous immune globulin(IVIG) is widely used for immune thrombocytopenic purpura (ITP), Kawasaki disease and other autoimmune neuromuscular disease. Aseptic meningitis was one of the most serious neurologic complications reported following the use of IVIG. We experienced 4 episodes of aseptic meningitis associated with IVIG usage in 3 patients from 2003 to 2004. Underlying disease of each patients was ITP, Kawasaki disease and myathenia gravis and all of them received high dose IVIG treatment for their underlying disease. Within a days, they started to complain severe headache and diagnosed meningitis by cerebrospinal fluid analysis. Cerebrospinal fluid leukocyte counts varied from 92 to over a thound per microliter with dominance of polymorphonuclear leukocytes. Microbiologic studies revealed no organisms. All of them were free from headache within 2 days and did not suffer any neurological sequelae.
A 37Ch Visible Adaptive Optics System for Wavefront Compensation
이준호,Byung Tae Choi,Eung Cheol Kang,Hae Seog Kho,Ho Jung Cheon,Jae Il Lee,Joon Won Kim,Kyung Muk Lee,Sung Jin Kim,Young Cheol Lee,Young Il Cho 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.1
A visible adaptive system was developed to compensate for phase distortions of a visible (He-Ne) laser. The visible adaptive optics (AO) system consists of 5 subsystems: a Shack-Hartmann wavefront sensor, a deformable membrane mirror of 15 mm with 37 actuators, a high-speed tip/tilt mirror of 20 mm, a position sensor and a control & display unit. The lab-developed Shack-Hartmann sensor was experimentally shown to have a measurement accuracy of better than RMS /50 at 0.6328 μm over the maximum phase distortion that the deformable mirror could generate, i.e., approximately /4. The adaptive optics system operated the deformable mirror at 10 Hz and the tip/tilt mirror at 30 Hz, which were, respectively, closed by the Shack-Hartmann sensor and the position sensor. The closed adaptive optics system was demonstrated to compensate for time-varying wavefront aberrations of PV (Peak-to-Valley) 1.2 μm with a time frequency of 1.4 Hz. The residual RMS wavefront error was shown to be smaller than 0.014 μm, i.e., /45 at 0.6328 μm.
복합 슬릿-마찰 감쇠장치가 적용된 철근 콘크리트 특수 모멘트 저항골조의 내진성능 평가
이준호,김기철,김진구,Lee, Joon-Ho,Kim, Gee-Cheol,Kim, Jin-Koo 한국공간구조학회 2017 한국공간구조학회지 Vol.17 No.4
This study develops a new hybrid passive energy dissipation device for seismic rehabilitation of an existing structure. The device is composed of a friction damper combined with a steel plate with vertical slits as a hysteretic damper. Analytical model is developed for the device, and the capacity of the hybrid device to satisfy a given target performance is determined based on the ASCE/SEI 7-10 process. The effect of the device is verified by nonlinear dynamic analyses using seven earthquake records. The analysis results show that the dissipated inelastic energy is concentrated on the hybrid damper and the maximum interstory drift of the SMRF with damping system satisfies the requirement of the current code.
이준호,김민철,조성우,김상원,Lee, Joon-Ho,Kim, Min-Cheol,Cho, Seong-Woo,Kim, Sang-Won 한국군사과학기술학회 2010 한국군사과학기술학회지 Vol.13 No.1
In this paper, the well-known LOB-based emitter localization using linear LSE algorithm is numerically implemented and the heuristic guidelines for the parameter values to achieve 1% RMS error are presented. In the simulation, we changed the total observation durations for LOB measurements, time interval between successive LOB measurements and sensor trajectories. The effects of the time interval of LOB measurements, the time duration of the LOB measurements and the angle of flight path arc on the performance are illustrated. The dependence of the performance on the various parameters is investigated and rule-of-thumbs for the parameter values corresponding to 1% RMS error are presented for each simulation condition.
이준호,채제욱,이성배,김현준,Lee, Joon-Ho,Chae, Je-Wook,Lee, Sung-Bae,Kim, Hyun-Jun 한국군사과학기술학회 2009 한국군사과학기술학회지 Vol.12 No.2
It is known that muzzle flash can be generated by the reaction between the oxygen in the air and unburned gunpowder contained in the propellant gas if a barrel is not long enough to burn gunpowder fully inside of the barrel. A hugh muzzle flash, which is a characteristic of small arms with short barrel length, disturbs a shooter in aiming at the target at night by making the shooter blind for a while and endangers the shooter's life by revealing firing position to enemies. In addition, the heat of muzzle flash can deteriorate the performance of thermal sights, which are attached to small arms for effective night combat. In this paper, flash suppressors of different shapes were designed for a newly developed 5.56mm caliber rifle with short barrel length and the performance of each flash suppressor to reduce the muzzle flash was compared by on-site test firing. Through the test firing, a highly efficient design of flash suppressor for reducing the muzzle flash was identified. The result of the paper can be referred when designing flash suppressors for small arms with short barrel length.
Kalman filter를 이용한 위치추정 알고리즘의 성능 분석
이준호,조성우,이동근,Lee, Joon-Ho,Cho, Seong-Woo,Lee, Dong-Keun 한국군사과학기술학회 2009 한국군사과학기술학회지 Vol.12 No.6
In this paper, the dependence of the Kalman filter-based emitter location algorithm on the initial estimate is investigated. Given all the LOB data, the initial estimate of the emitter location is obtained from the linear LSE algorithm with the former LOB data. Using the initial estimate, the Kalman filter algorithm is applied with the remaining LOB data to update the initial estimate. It is shown that as the number of data used in the calculation of the initial estimate increases, the accuracy of the final estimate is improved and the total computational complexity of obtaining the initial estimate and the final estimate increases. In addition, the dependence of the performance of the Kalman filter algorithm on the predefined constant is illustrated.
신호원 위치의 편향성 및 센서 이동경로에 따른 선형 LSE 알고리즘 기반 신호원 위치 추정 성능
이준호,조성우,김민철,진용기,이창훈,Lee, Joon-Ho,Cho, Seong-Woo,Kim, Min-Cheol,Jin, Yong-Ki,Lee, Chang-Hoon 한국군사과학기술학회 2009 한국군사과학기술학회지 Vol.12 No.5
In this paper, passive direction-finding localization of the emitter using noisy line-of-bearing (LOB) measurements is considered. The performance of the LOB-based emitter localization using linear LSE algorithm is given. The Dependence of the performance on bias of emitter location and sensor trajectory is illustrated using the numerical results.
이준호,여운주,최의중,Lee, Joon-Ho,Yeo, Woon-Joo,Choe, Eui-Jung 한국군사과학기술학회 2009 한국군사과학기술학회지 Vol.12 No.3
In the traditional percussion locks of small arms, a firing pin is struck by a hammer rotating on a single center of rotation, which makes the percussion mechanism simple and reliable. In order to strike the firing pin by the hammer, however, the firing pin should be located within the radius of rotation of the hammer. As the distance between the striking point of the firing pin and the center of rotation of the hammer becomes longer, the radius of rotation of the hammer should also be increased, which results in the increase of the volume and weight of the small arms because the hammer needs the more space for its operation inside of the small arms. In this paper, a link type percussion lock was newly proposed in order to overcome the limitation of designing small arms when using traditional percussion locks, as mentioned above. The link type percussion lock was modeled by using multi-body dynamics software and designed to satisfy the requirements such as striking force level of the hammer exerting on the firing pin enough to detonate the percussion cap of ammunitions and the safety on the accidental drop. It was applied to the newly developed dual-barrel weapon system, in which the weight and overall length are important design factors, and verified by durability test and drop test on the ground.
방위각을 이용한 신호원 위치 추정 알고리즘의 성능 비교
이준호,김민철,조성우,진용기,이동근,Lee, Joon-Ho,Kim, Min-Cheol,Cho, Seong-Woo,Jin, Yong-Ki,Lee, Dong-Keun 한국군사과학기술학회 2009 한국군사과학기술학회지 Vol.12 No.4
In this paper, we present the performance of the LOB(line of bearing) - based emitter localization algorithm. The linear LSE(least-squared error) algorithm, nonlinear LSE algorithm and Stansfield algorithm are considered. In addition, we focus on the performance improvement of the weighted estimation compared with the unweighted estimation. Each estimation algorithm is briefly introduced, and the performance of the algorithm is illustrated using the numerical results.