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      • KCI등재

        「心因性皮膚疾患크리닉」환자들에 關한 豫備調査

        金哲應,趙斗英,姜民熙 大韓神經精神醫學會 1985 신경정신의학 Vol.24 No.1

        1983年 3月부터 1984年 2月까지 서울大學校病院 皮膚科 외래진료소내의 「心因性皮膚疾患크리닉」에 諮問依賴된 患者 51명 (남:32명, 여:19명) 을 對象으로 社會人口學的持性을 調査分析하고 呼訴하는 症狀, 身體部位, 依賴前 皮膚科診斷, 依賴後 精神科的 診斷 및 治療등에 대해 분석하고 이를 外國의 경우와 比較ㆍ考察하였다. 1. 男ㆍ女 비율은 男子에서 높았고 (1.68:1), 年齡別 有意한 差異는 없었다. 2. 職業은 非生産的인 狀態가 많았고 (68.18%) 經濟狀態는 中下位가 많았다. 3. 依賴된 患者는 대부분 (8401%) 이 皮膚疾患과는 관계없이 精神疾患者이었다. 4. 呼訴하는 증상은 瘙痒感이 가장 많았다(29.55%) 5. 呼訴하는 身體部位는 男子의 경우 肛門生殖器部位(45.45%), 女子는 顔面部位 (54.55%)가 많았다. 6. 객관적인 皮膚病變은 男子, 78.57%, 女子의 82.25%에서 없었다. 7. 依賴前 皮膚科診斷은 「診斷保留」가 많았고 (38.69%), 精神科的診斷은「單症性健康念慮精神病 」이 많았다 (25.0%). 8. 精神科治療를 권유 했을때 거부하는 例가 많았으나 (46.15%) 6개월이상의 장기 추적치료는 精神科外來에서 하는게 더 효과적이다. 이상의 結果에서 시사되는 바와 같이 본 크리닉에서의 정신과 諮問醫의 연결활동은 여러면에서 의의가 있었다. 그러나 본 연구조사는 소수의 대상환자들에게서 관찰된 것인 바 앞으로 본 크리닉에 의뢰되는 더 많은 환자들을 對象으로 한 각각의 문제점에 대한 철저한 硏究는 물론 개개의 환자들에 대한 보다 더 깊이있는 정신의학적 접근이 필요하다고 생각된다. In 1983 the psychodermatoloy outpatient clinic was established at the Seoul National University Hospital, open one afternoon a week, where one liaison-psychiatrist and one dermatologist conjointly treat the patients referred from the dermatology outpatient clinic. This study purported to investigate the demographic characteristics and clinical aspects of the total 51 patients treated at the clinic during the period from March 1, 1983 to Feb. 28, 1984, and the results were summarized as follows; (1) Males predominated over females (62.7% vs 36.6%) and there were no age-specific findings. Majority of the patients came from middle-and-lower socioeconomic classes (90.0%) and majority of the patients suffered from psychiatric problems rather than actual dermatologic disorders (81.0%). (2) Pruritus was the most frequent complaint among them, with males on the anogenital regions (45.5%) and females on the facial region (54.6%), and the most frequent psychiatric diagnosis was monosymptomatic hypochondriacal psychosis (25.0%). (3) While two-fifth (42.1%) of the patients dropped-out after 1-2 visits, the fact that another two-fifth (39.5%) continued to visit the clinic more than 5 times showed our liaison activities gave some positive impacts in the care of psychodermatologic problems. It also seemed that with a better psychological preparations for those patients upon the referral by the dermatologists the early drop-out rate could be markedly reduced.

      • KCI등재
      • A comparison between central blood pressure values obtained by the Gaon system and the SphygmoCor system.

        Kang, Jun Hyuk,Lee, Dae In,Kim, Sua,Kim, Sun Won,Im, Sung Il,Na, Jin Oh,Choi, Cheol Ung,Lim, Hong Euy,Kim, Jin Won,Kim, Eung Ju,Han, Seung Woo,Rha, Seung-Woon,Seo, Hong Seog,Oh, Dong Joo,Park, Chang G Japanese Society of Hypertension 2012 Hypertension research Vol.35 No.3

        <P>Central pulse pressure is correlated with carotid atherosclerosis and the incidence of cardiovascular events more significantly than brachial pulse pressure. Augmentation index (Aix) has been shown to be an independent predictor of cardiovascular morbidity and mortality. Pulse wave analysis using the Gaon system allows for the estimation of central blood pressure (CBP), corrected augmentation index (Aix@HR75), ejection duration (ED) and subendocardial viability ratio (SEVR), and is widely used in clinical research in Korea. However, the accuracy of this system is controversial. From February 2008 to March 2011, 99 patients were recruited for this study. Measurements were taken both by the Gaon system and the SphygmoCor system on the same day for all study participants. The estimated values of CBP, Aix@HR75, ED and SEVR for the two systems were compared using paired t-tests, simple correlation analyses and Bland-Altman plots. Systolic blood pressure (SBP) estimated by the two systems was significantly (P<0.001) correlated; the coefficient was 0.982. The two s.d. of the difference in SBP between these systems was quite small--<7?mm?Hg. Aix@HR75, ED and SEVR as estimated by the two systems were also significantly correlated, although they, especially SEVR, showed much weaker correlations than were observed in SBP: coefficients for Aix@HR75, ED and SEVR were 0.727, 0.648 and 0.230, respectively. We assessed the CBP of Korean patients estimated by the two systems and observed that the correlations of Aix, ED and SEVR were weaker than that of CBP. Such variations may be due to the difference in measuring methods between the devices. As even a slight change in pulse waveforms may result in a large difference in estimations, parameters, including Aix@HR75, ED and SEVR, should be carefully interpreted by experienced clinicians.</P>

      • Time-dependent prognostic effect of high sensitivity C-reactive protein with statin therapy in acute myocardial infarction

        Kang, Dong Oh,Park, Yoonjee,Seo, Ji Hoon,Jeong, Myung Ho,Chae, Shung Chull,Ahn, Tae Hoon,Jang, Won Young,Kim, Woohyeun,Park, Eun Jin,Choi, Byoung Geol,Na, Jin Oh,Choi, Cheol Ung,Kim, Eung Ju,Rha, Seun Elsevier 2019 Journal of cardiology Vol.74 No.1

        <P><B>Abstract</B></P> <P><B>Background</B></P> <P>Elevated high sensitivity C-reactive protein (hs-CRP) in acute myocardial infarction (AMI) patients undergoing percutaneous coronary intervention (PCI) has prognostic value for future cardiovascular events. This study aimed to ascertain a valid prognostic time-period for predicting cardiovascular outcome based on baseline hs-CRP in AMI patients undergoing successful PCI on statin therapy.</P> <P><B>Methods</B></P> <P>Overall, 4410 AMI patients were enrolled from the Korea Acute Myocardial Infarction-National Institutes of Health (KAMIR-NIH) registry. Participants were divided into groups according to cut-off values of baseline hs-CRP (1.0, 3.0, and 10.0mg/L) and statin therapy intensity. The primary outcome was 36-month major adverse cardiovascular events (MACE), a composite of all-cause mortality, any myocardial infarction, and repeat revascularization. The secondary outcome was MACE developed 0–6, 6–12, and 12–36 months after AMI.</P> <P><B>Results</B></P> <P>The overall incidence of 36-month MACE was significantly higher as baseline hs-CRP increased (by groups: 8.8% vs. 8.6% vs. 10.7% vs. 15.4%, log-rank <I>p</I> <0.001). The prognostic effect of baseline hs-CRP was mostly confined to the first 6 months after AMI (0–6 months MACE by groups: 1.6% vs. 2.3% vs. 4.3% vs. 6.1%, log-rank <I>p</I> <0.001) and attenuated in high-intensity statin users. Six months after AMI, this prognostic effect of baseline hs-CRP was remarkably reduced (6–12 month MACE by groups: 2.4% vs. 2.1% vs. 2.8% vs. 4.0%, log-rank <I>p</I> =0.111, 12–36 month MACE by groups: 4.7% vs. 4.1% vs. 4.0% vs. 6.2%, log-rank <I>p</I> =0.218); however, high-intensity statin treatment showed a consistent improvement in outcome. The observed time-dependent prognostic effects remained consistent following multivariate analysis.</P> <P><B>Conclusions</B></P> <P>The prognostic impact of elevated hs-CRP at baseline was most evident during the first 6 months after AMI; however, the use of high-intensity statin persistently improved the clinical outcome even after the resolution of inflammatory reactions.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The prognostic impact of baseline high sensitivity C-reactive protein (hs-CRP) was mostly confined to the first 6 months. </LI> <LI> High-intensity statin attenuated the prognostic impact of baseline hs-CRP elevation. </LI> <LI> Dose-dependent anti-inflammatory effect of statin is dominant over the first 6 months. </LI> <LI> High-intensity statin persistently improved outcome after first 6 months of acute myocardial infarction. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P> <B>Time-dependent prognostic effect of baseline hs-CRP and high-intensity statin therapy after AMI.</B> </P> <P>The prognostic impact of elevated hs-CRP at baseline was mostly confined to the first 6 months after AMI, and high-intensity statin therapy persistently improved the clinical outcome over the extended follow-up period. The observed beneficial effect of high-intensity statin therapy was attributed to both the anti-inflammatory and cholesterol-lowering effects during the early 6 months; and predominantly to cholesterol-lowering effects in the later periods.</P> <P>AMI, acute myocardial infarction; hs-CRP, high sensitivity C-reactive protein; MACE, major adverse cardiovascular events.▪</P>

      • KCI등재

        태안화력발전소 비산재로부터 리튬용출연구

        김강주 ( Kang Joo Kim ),이은규 ( Eung Yu Lee ),이재철 ( Jae Cheol Lee ),황수연 ( Soo Yeon Hwang ),김창현 ( Chang Hyeon Kim ) 한국광물학회 2012 광물과 암석 (J.Miner.Soc.Korea) Vol.25 No.2

        본 연구에서는 (주)한국서부발전의 태안화력발전소에서 생산된 비산재로부터 Li의 용출을 고찰하였다. 본 연구에서는, 반응용액:석탄회 비율, 반응용액의 종류(해수, 증류수), CO2가스의 조건에 따른 Li 용출량을 관찰하였다. 실험 결과, 반응용액의 Li 농도는 고체:용액 비율이 증가함에 따라 계속하여 증가하는 양상을 보였다. 비산재 단위 질량당 Li 용출은 증류수를 사용하였을 때, 그리고 CO2가스의 용해가 제한되었을 때 증가되었으며, 이는 그러한 조건에서 CaCO3의 침전이 억제되었기 때문이다. 해수내 Li의 흡착추출에 방해되는 Mg2+도 고체:용액 비를 증가시킴으로써 효과적으로 제거할 수 있었다. The leaching of Li from fly ashes was studied. The fly ash produced from the Taean electric power plant of the Korea Western Power Co., Ltd. was used for this study. The Li leaching was observed according to the changes in solid:solution ratio, solution types (seawater or deionized water), and the CO2 condition in the atmosphere. The results showed that the Li concentrations in the solution increased continuously as the solid:solution ratio increased. The Li leaching per unit mass of fly ash was greater when the deionized water was used for the experiment and when the CO2 dissolution is limited during the reaction because the precipitation of CaCO3 is suppressed under those conditions. At high solid:solution ratio, Mg 2+ , the ion preventing the Li extraction from seawater by adsorption, was effectively removed from the seawater.

      • Mid-term angiographic benefit of sirolimus-eluting stents compared with paclitaxel-eluting stents in patients with acute myocardial infarction

        Choi, Cheol Ung,Rha, Seung-Woon,Chen, Kang-Yin,Jin, Zhe,Minami, Yoshiyasu,Shin, Seung Yong,Na, Jin Oh,Suh, Soon Yong,Lim, Hong Euy,Kim, Jin Won,Kim, Eung Ju,Park, Chang Gyu,Seo, Hong Seog,Oh, Dong Joo Elsevier 2009 Journal of cardiology Vol.54 No.1

        <P><B>Summary</B></P><P><B>Background</B></P><P>We compared angiographic and clinical outcomes among different drug-eluting stents (DESs) in Korean acute myocardial infarction (AMI) patients.</P><P><B>Methods</B></P><P>A total of 109 consecutive AMI patients who underwent percutaneous coronary intervention (PCI) with either sirolimus-eluting (SES, <I>n</I>=56 pts) or paclitaxel-eluting stents (PES, <I>n</I>=53 pts) were enrolled from August 2004 to December 2006. The angiographic outcomes at 6 months and clinical outcomes at 1 year were compared between the two groups.</P><P><B>Results</B></P><P>Baseline clinical and procedural characteristics were similar between the two groups. At 6 months, the rate of binary restenosis was 17.0% in the PES group compared with 3.6% in the SES group (<I>p</I>=0.026). Percent restenosis was 24.9±28.6% in the PES group compared with 11.2±17.6% in the SES group (<I>p</I>=0.004). Length of restenosis segment was 3.21±9.02mm in the PES group compared with 0.89±2.38mm in the SES group (<I>p</I>=0.048). Late loss was 0.73±0.89mm in the PES group compared with 0.28±0.37mm in the SES group (<I>p</I>=0.001). However, there were no differences in clinical outcomes at 1 year including mortality, myocardial infarction, repeat PCI, and major cardiac adverse events between two groups.</P><P><B>Conclusion</B></P><P>SES implantation in patients with AMI was associated with reduction in angiographic restenosis at 6 months compared with PES, however, these angiographic benefits were not translated into better clinical outcomes in real world clinical practice.</P>

      • SCISCIESCOPUS

        Development of Microstrain in Aged Lithium Transition Metal Oxides

        Lee, Eung-Ju,Chen, Zonghai,Noh, Hyung-Ju,Nam, Sang Cheol,Kang, Sung,Kim, Do Hyeong,Amine, Khalil,Sun, Yang-Kook American Chemical Society 2014 NANO LETTERS Vol.14 No.8

        <P>Cathode materials with high energy density for lithium-ion batteries are highly desired in emerging applications in automobiles and stationary energy storage for the grid. Lithium transition metal oxide with concentration gradient of metal elements inside single particles was investigated as a promising high-energy-density cathode material. Electrochemical characterization demonstrated that a full cell with this cathode can be continuously operated for 2500 cycles with a capacity retention of 83.3%. Electron microscopy and high-resolution X-ray diffraction were employed to investigate the structural change of the cathode material after this extensive electrochemical testing. It was found that microstrain developed during the continuous charge/discharge cycling, resulting in cracking of nanoplates. This finding suggests that the performance of the cathode material can be further improved by optimizing the concentration gradient to minimize the microstrain and to reduce the lattice mismatch during cycling.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/nalefd/2014/nalefd.2014.14.issue-8/nl5022859/production/images/medium/nl-2014-022859_0012.gif'></P>

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