한국영화 스태프(staff) 경력인증 시스템구축에 관한 소고

최은화 영화진흥위원회 2016 현안보고(이슈페이퍼) Vol.- No.-

Macrolide계 항균제 내성 출현과 소아에서의 임상적 적용

최은화 대한소아청소년과학회 2008 Clinical and Experimental Pediatrics (CEP) Vol.51 No.10

Macrolide antimicrobial agents including erythromycin, roxithromycin, clarithromycin, and azithromycin are commonly used in the treatment of respiratory tract infections in children. Newer macrolides that have structural modifications of older drug erythromycin show improved change in the spectrum of activity, dosing, and administration. However, recent studies reported that increasing use of macrolide antibiotics is the main force driving the development of macrolide resistance in streptococci. In particular, azithromycin use is more likely to select for macrolide resistance with Streptococcus pneumoniae than is clarithromycin use, a possible reflection of its much longer half life. Recently, erythromycin resistance rates of S. pneumoniae and Streptococcus pyogenes are rapidly increasing in Korea. Two main mechanisms of acquired macrolide resistance have been described, altered binding site on the bacterial ribosome encoded by the ermB gene and active macrolide efflux pump encoded by the mef gene. Relationship between the susceptibility of S. pneumoniae and the response to macrolides has been shown in studies of acute otitis media, but less clear in cases of pneumonia. This article reviews the spectrum of activity, pharmacokinetic properties, mechanisms of action and resistance, and clinical implication of resistance on the treatment of respiratory tract infections in children.

영아의 만족지연능력과 만족지연전략 및 어머니의 양육방식간의 관계

최은화,조복희 한국보육지원학회 2005 한국보육지원학회지 Vol.1 No.1

본 연구에서는 영아의 만족지연능력과 만족지연전략 및 어머니의 통제성간의 관계를 알아보았다. 연구대상은 18-36개월의 영아였으며 만족지연능력 측정 실험은 Mischel(1974)이 고안한 자기 만족지연 실험을 Rha(1999)가 연령에 맞게 번안한 것을 사용하였다. 만족지연능력에 사용되는 전략으로는 직접응시 전략과 주의분산 전략으로 분류하여 관찰하였으며 어머니의 양육방식은 조복희, 이진숙, 이홍숙 그리고 권희경(1999)에 의해 개발된 척도의 일부인 통제 13문항을 발췌하여 사용하였다. 연구결과 영아의 월령이 증가함에 따라 만족지연능력이 증가하며, 영아가 사용하는 만족지연전략은 월령이 높아질수록 주의분산전략을 더 많이 사용하는 것으로 나타났다. 또한 영아의 월령, 만족지연 전략인 직접응시 전략과 주의분산 전략은 영아의 만족지연능력에 유의미한 영향을 주었다.

Recommendation for use of the newly introduced pneumococcal protein conjugate vaccines in Korea

최은화,김경효,김예진,김종현,박수은,이환종,은병욱,조대선,최경민,홍영진 대한소아청소년과학회 2011 Clinical and Experimental Pediatrics (CEP) Vol.54 No.4

Streptococcus pneumoniae remains a leading cause of invasive infections including bacteremia and meningitis, as well as mucosal infections such as otitis media and pneumonia among children and adults. The 7-valent pneumococcal conjugate vaccine (PCV7)was licensed for use among infants and young children in many countries including Korea. The routine use of PCV7 has resulted in a decreased incidence of invasive pneumococcal disease (IPD) by the vaccine serotypes among the vaccinees and substantial declines in IPD among unvaccinated populations such as older children and adults as well. In addition, there are increasing evidences to suggest that routine immunization with PCV7 is changing the epidemiology of pneumococcal diseases such as serotype distribution of IPD,nasopharyngeal colonization, and antibiotic resistance patterns. In contrast, there is an increase in the number of IPDs caused by nonvaccine serotypes, though it is much smaller than overall declines of vaccine serotype diseases. Several vaccines containing additional serotypes have been developed and tested clinically in order to expand the range of serotypes of Streptococcus pneumoniae. Recently two new pneumococcal protein conjugate vaccines,10-valent pneumococcal conjugate vaccine (PCV10) and 13-valent pneumococcal conjugate vaccine (PCV13), have been approved for use in several countries including Korea. This report summarizes the recommendations approved by the Committee on Infectious Diseases,the Korean Pediatric Society.

흡연 후 발생한 급성 호산구성 폐렴 1예

최은화,장혜정,강민정,오지영,김인제,심윤수,문진욱,장중현,이진화,성순희 이화여자대학교 의과학연구소 2006 EMJ (Ewha medical journal) Vol.29 No.2

후복막에 발생한 낭종성 혈관육종: 1예 보고

최은화,고지호 대한초음파의학회 2008 ULTRASONOGRAPHY Vol.27 No.2

혈관육종은 드문 종양이다. 특히 혈관육종이 낭종성 변화를 보여 후복막에 생긴 경우 다른 후복 막의 낭종성 종양과 감별이 어렵다. 이에 저자들은 복통을 주소로 내원한 61세 여자 환자에서 후 복막에 발생하여 낭종성 변화를 보인 혈관육종을 경험하였기에 보고하고자 한다. 시행한 초음파와 CT 에서 불규칙한 격막과 벽의 비후가 있는 다방성 낭성종괴가 후복막에서 관찰되었고, 조영증강 CT 에서 낭성종괴의 불규칙한 벽이 조영증강되었다. 종괴는 적출술 후 조직검사에서 혈관육종으로 확진되었다. A retroperitoneal angiosarcoma is rare. Especially, a cystic change in retroperitoneal angiosarcoma is extremely rare and it is difficult to distinguish an angisarcoma with a cystic change in the differential diagnosis with other retroperitoneal cystic masses. We report here a case of a cystic change in a retroperitoneal angiosarcoma of a 61-year-old woman who complained of abdominal pain. Imaging studies, including ultrasonography and computed tomography, detected a lobulating cystic mass with inner enhancing irregular septations and walls in the retroperitoneum. The tumor was surgically resected and was histopathologically diagnosed as an angiosarcoma.

Endovascular Treatment with a Stent-Graft for Internal Carotid Artery Laceration during Trans Sphenoidal Surgery: A Case Report

최은화,고지호,이태홍,노명호 대한영상의학회 2008 대한영상의학회지 Vol.59 No.3

An internal carotid artery (ICA) tear during or after trans-sphenoidal surgery (TSS) is rare but may cause potentially lethal complications. A 23-year-old female patient visited our hospital for treatment of a Rathke’s cleft cyst. The patient had massive hemorrhage during surgery and angiography performed after surgery showed laceration of the cavernous ICA. We successfully controlled the hemorrhage with emergency placement of an endovascular stent-graft.

Protection against Severe Varicella Disease

최은화 대한의학회 2019 Journal of Korean medical science Vol.34 No.10

Although varicella is considered as a benign childhood disease, it is potentially severe and represents a considerable health burden. Thus, safe and effective approaches are needed to prevent varicella. The development of varicella vaccine dates back to 1974, using Oka strain of varicella zoster virus.1 One or two dose schedules have been effective in preventing varicella, particularly moderate to severe disease. In the United States, data suggest that there was an 87% decline in hospitalizations and 66% decline in deaths due to varicella following the widespread use of one dose of varicella vaccine.2 While there have been substantial reductions in varicella-related deaths and complications, varicella outbreaks have been occurring among highly vaccinated school children as the form of breakthrough varicella.

소아에서 원인불명열의 진단적 접근 - 감염성 질환을 위주로 하여-

최은화 대한소아청소년과학회 2007 Clinical and Experimental Pediatrics (CEP) Vol.50 No.2

Fever of unknown origin (FUO) has been a convenient term used to classify patients who warrant a particular systemic approach to diagnostic evaluation and management. The greatest clinical concern in evaluating FUO is identifying patients whose fever has a serious or life-threatening cause when a delay in diagnosis could jeopardize successful intervention. Thorough history and complete physical examination are critical to uncover the etiologic diagnosis. Most cases of FUO in children are caused by atypical presentations of common diseases rather than by typical manifestations of rare disorders. Selection of diagnostic tests and speed of investigation should be guided by a knowledge of the disease severity, patient age, epidemiologic and geographic information, and any positive findings from a detailed history and physical examination. The three most common causes of FUO in children are infectious diseases, connective tissue diseases, and malignancy. In general, the prognosis of FUO in children is better than that of adults. Although the outcome is dependent on the primary disease process, fever abates spontaneously in most cases in whom the cause of fever remains unclear.

지문정보를 이용한 안전한 암호키 저장 시스템 개발

최은화,서창호,임종태,김석우 公州大學校 工學硏究院 生産技術硏究所 2003 論文集 Vol.11 No.-

Biometric encryption refers to a process of secure key management. Biometric encryption does not directly provide a mechanism for the encryption/decryption of data, but rather provides a replacement to typical passcode key-protection protocols. Although the process of biometric encryption can be applied to any biometric image, the initial implementation was achieved using fingerprint images.