Immobilization with Ketamine HCI and Tiletamine-Zolazepam in Cynomolgus Monkeys

Myung-cheol Kim,Sung-hyeok Hong,Soo-jin Lee,Young-suk Kim,Jae-il Lee 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2

with Ketamine HCl and Tiletamine-Zolazepam in Cynomolgus MonkeysJae-il Lee, Sung-hyeok Hong, Soo-jin Lee, Young-suk Kim and Myung-cheol Kim*Laboratory of Veterinary Surgery, College of Veterinary Medicine, Chungnam National University, Daejeon 305-764, KoreaReceived March 4, 2003 / Accepted July 2, 2003J. Vet. Sci. (2003), 4(2), 187-191JOURNAL OFVeterinaryScience*Corresponding author: Myung-cheol Kim Laboratory of Veterinary Surgery, College of Veterinary Medicine, Chungnam National University, Daejeon 305-764, Korea Tel: +82-42-821-6757, Fax: +82-42-822-4216 E-mail: mckim@cnu.ac.kr

체성감각유발전위검사를 이용한 척추기형교정수술 시의 수술중 감시

김철,이창헌,김창효,석세일,김진혁,김원중,홍기혁 大韓再活醫學會 1999 Annals of Rehabilitation Medicine Vol.23 No.3

금속착제를 갖는 산소부화막의 제조

김진환,이우태,김종혁 全南大學校 觸媒硏究所 1996 觸媒硏究 論文集 Vol.18 No.-

Composite membranes containing a metal complex as an oxygen carrier were prepared and tested for the capability of oxygen enrichment. The permeability characteristics of the membrane were measured by the volumetric method with the pressure difference ranging from 0.2 to 0.8Kg/cm². Both oxygen and nitrogen showed constant permeabilities, diffusion coefficients, and solubilities which do not depend on the pressure difference across the membrane. The metal complexes were also found to play a role of nitrogen carrier to a degree. For the case of the silicone membrane with Co(NO₃)₂.6H₂O complex, the permeability and the separation factor of oxygen were significantly improved to ??/cm³·cm/cm²·sec·cm-Hg and 2.7 respectively, at the pressure difference of 0.4Kg/cm². This improvement was attributed to the metal complex which acts as an oxygen carrier and thus increases the solubility of oxygen in the membrane.

제지공정수 최적화를 위한 UF의 적합성 평가 및 응용

김형진,이지영,권혁윤 한국공업화학회 2004 응용화학 Vol.8 No.1

This study was carried out to evaluate the application possibility of UF Membrane System to papermaking industry in order to optimize the recycling of white water. In this study, for the efficiency test of UF modules, the MWCO(molecular weight cut-off) of the membrane was estimated by the COD measurement from UF filtrate water. From the rejection rate of membrane, three kinds of UF module were selected and evaluated in the factors of COD, SS, turbidity and flow rate.

옥수수 播種期와 地上部形質에 관한 硏究

金鎭淇,崔京求,白南赫,陳星桂 全北大學校 1982 論文集 Vol.24 No.-

全北 平野地인 裡里地方에서 옥수수의 播種期와 地上部生育 및 種實收量과의 관계를 調査하여 다음과 같은 결과를 얻었다. 1. 播種期의 早晩이 莖葉의 生育 및 種實收量에 크게 영향을 끼치며 播種이 늦어질수록 出雄, 出絲, 生育日數가 짧아지고 地上部生育은 떨어지는 경향이다. 2. 莖葉生育은 4月 20日 播種을 基點으로, 種實收量은 5月 5日 播種을 基點으로 各各 減少되었다. 3. 地上部諸形質과 種實收量간에는 高度의 正의 相關이 인정되며 種實增收를 위하여는 莖葉生育은 크게 할 필요가 있다. Some results were gained through the experiment that was carried out with a single cross cultivar, Suweon 19, of maize (Zea mays L.) in Iri, the Jeonbug plain area, in 1980, to check relationships between growth characters at different sowing dates. 1. The foliage growth and grain yield were greatly influenced with planting season. The number of days to tasseling, silking, or maturing shortened and the growth of maize decreased as sowing was delayed. 2. The threshold sowing date for foliage production seemed to be April 20 and that for grain yield, May 5. 3. Highly significant positive correlation existed between vegetative growth and grain yield. This may mean that increasing vegetative growth is prerequisite to better grain yield.

Quartz 자극에 의한 iNOS 발현의 자가조절

김경아,남혜윤,문제혁,정진숙,임영,정치경 大韓産業醫學會 2001 대한직업환경의학회지 Vol.13 No.4

목적 : Rat2 섬유모세포에서 α-quartz에 의해 유도된 NOS의 조절기전을 알아보기 위하여 본 연구가시도 되었다. 방법 : Rat2 세포에 있어서 α-quartz 자극에 의한 NO와 H₂O₂의 분비 및 iNOS의 발현을 관찰하였고, iNOS 억제제인 L-NIL과 H₂O₂ 억제제인Catalase를 전처리하고 마찬가지로 NO와 H₂O₂분비 그리고 iNOS의 단백발현 정도를 western blot-ting을 이용하여 관찰하였다. 결과 : o-quartz는 Rat2 세포에서 iNOS에 의한NO와 H₂O₂의 분비를 유도하였다. L-NIL은 R3t2세포에서 D-quartz에 의한 H₂O₂의 분비와 iNOS발현을 완전히 억제하였다. Catalase로 전처리 하였을 때 o-quartz로 유도된 iNOS에 의하여 생산증가된 H2Oa가 iNOS를 억제하는 autoinhibitorypathway가 차단되어 결과적으로 H₂O₂의 분비와 iNOS의 발현이 증가하였다. 결론 : Rat2 세포에서 α-quartz에 의하여 유도된iNOS는 H₂O₂의 분비를 촉진하고 이 H₂O₂는 iNOS기능을 조절하는 자가조절기전에 중요한 역할을 하는 것으로 생각된다. Objectives : This study was performed in order to investigate the molecular mechanism regulating nitric oxide synthase (NOS) induced by α-quartz in Rat2 fibroblast. Methods : α-quartz-induced nitric Oxide (NO) anti H₂O₂ formation anti α-quarts-induced iNOS protein expression in Rat2 fibroblast were monitored. With iNOS inhibitor (L-N6- (1-iminoethyl) lysine hydrochloride, L-NIL) or antioxidant (catalase), we observed NO and H₂O₂ formation and iNOS protein expression in Rat2 fibroblast stimulated with α-quartz. Results : α-quartz stimulated iNOS-induced NO and H₂O₂ formation in Rat2 fibroblast. L-NIL inhibited H₂O₂ formation and iNOS protein expression by α-quartz in Rat2 fibroblast. Pretreatment with catalase blocked the autoinhibitory pathway of iNOS by iNOS-induced H₂O₂ therefore H₂O₂ and NO production and iNOS protein expression were increased in Rat2 fibrobalst stimulated with α-quartz Conclusion : α-quartz-induced iNOS Stimulated H₂O₂ formation in Rat2 fibroblast. INOS-induced H₂O₂ by α-quartz plays an important role in the autoinhibition pathway for regulating the iNOS function in Rat2 fibroblast

慶南地域의 犯罪實態에 관한 硏究

김진혁 경남대학교 경남지역문제연구원 2003 경남지역연구 Vol.9 No.-

유한요소법을 이용한 밸브 스프링 리테이너의 형상설계

신혁수, 김동범, 박진근, 이인환, 조해용 충북대학교 산업과학기술연구소 2013 산업과학기술연구 논문집 Vol.27 No.2

A valve spring retainer is a small disc and located at intake and exhaust valve stem of engine. The retainer supports a valve spring and transmits spring force to a valve. Force is applied to the retainer repeatedly by a rocker arm. Durability of the retainer is an important factor of performance. Weight of retainer affect dynamic performance of engine. Therefore, optimal strength and weight of the retainer design are needed. In this study, stress distribution and fracture load of retainer were analyzed by using FEM to design optimal strength and weight. Static load test was simulated by using commercial FEM code DEFORM-3D. Shapes of the retainer to reduce weight were designed and analyzed to verify validity of it. Simulated results and experimental ones were compared

하이퍼큐브 멀티컴퓨터상의 효율적인 커뮤니케이션 관리

우진운,김혁수 단국대학교 1996 論文集 Vol.30 No.-

The hypercube is a widely used topology for the interconnection network connecting processors of multicomputer, due to the economic and structural features. The communication of hypercube multicomputer is one of considerations to enhence the efficiency of programs. In the most systems, the communication is done by calling subroutines and messages are passed through the shortest path. In this work, we propose a communication management algorithm that keeps track of the communication routines where errors frequently occur in the hypercube programs. As a result, this algorithm can prevent processors from having a deadlock when executing programs in the hypercube system.

결정형 규산분진에 폭로된 섬유모세포의 자가증식 : Evaluation by H₂O₂and PDGF-AA 와 TGFβ

안병용,김경아,문제혁,정진숙,김은경,임영 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

Objectives : The aim of this study is to find out the activity of autoproliferation of rat fibroblast exposed to crystalline silica and the role of mediators secreted from rat fibroblast. Methods : The effect of α-quartz on production of growth factor (platelet-derived growth factor-AA and transforming growth factorβ) from rat fibroblasts were evaluated by ELISA and immunocytochemical analysis. Gene expression of these growth factors in rat fibrobast exposed to crystalline silica was evaluated by RT-PCR. Furthermore, fibroblast proliferation by culture supernatant of rat fibroblast was assayed by the neutral red test. Results : The amounts of H2O2 and growth factors synthesized in rat fibroblasts were significantly increased by the stimulation of crystalline silica (α-quartz) , which showed the dose-dependent manner to the concentration of α-quartz with the maximum response at the dosage of 100 ㎍/㎠. The result of RT-PCR demonstrated that α-quartz induced gene expression of PDGF-AA and TGFβ in rat fibroblast. We also found that supernatant of α-quartz-cocultured rat fibroblast induced a significant proliferation of fibroblast. Conclusion : Crystalline silica directly induce functional change In fibroblast such as increased release of reactive oxygen species and growth factors. The products of these functional change promote fibroblast proliferation via autocrine loop.