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대학생의 취업스트레스와 자아존중감, 자아효능감, 외모관리행동의 관계
김보라,김유진,김지희,노혜진,오승희,홍지혜,황윤희,박선아 水原大學校 2016 論文集 Vol.30 No.-
Purpose: Many university students are under a lot of job-seeking stress because the employment rate is low. This study sought to determine the relationship between job-seeking stress, self esteem, self efficacy and appearance management behavior amongst university students focusing on nursing. Methods: This descriptive correlational study evaluated the relationships between job-seeking stress, self esteem, self efficacy and appearance management behavior of 340 university students was conducted between September 1 and October 5, 2015. Results: The correlational analysis between job-seeking stress, self esteem, self efficacy and appearance management behavior revealed a negative correlation between job-seeking stress, self esteem and self efficacy and a positive correlation between job-seeking stress and appearance management behavior. In addition, age also correlated with self esteem, self efficacy and appearance management behavior. Conclusion: Stress correlated with self esteem and self efficacy and appearance management behavior. Therefore job-seeking stress may be reduced through not only self esteem and self efficacy enhancement programs but also management according to age.
A genome-wide association study of a coronary artery disease risk variant.
Lee, Ji-Young,Lee, Bok-Soo,Shin, Dong-Jik,Woo Park, Kyung,Shin, Young-Ah,Joong Kim, Kwang,Heo, Lyong,Young Lee, Ji,Kyoung Kim, Yun,Jin Kim, Young,Bum Hong, Chang,Lee, Sang-Hak,Yoon, Dankyu,Jung Ku, Hy Springer-Verlag 2013 Journal of human genetics Vol.58 No.3
<P>Although over 30 common genetic susceptibility loci have been identified to be independently associated with coronary artery disease (CAD) risk through genome-wide association studies (GWAS), genetic risk variants reported to date explain only a small fraction of heritability. To identify novel susceptibility variants for CAD and confirm those previously identified in European population, GWAS and a replication study were performed in the Koreans and Japanese. In the discovery stage, we genotyped 2123 cases and 3591 controls with 521 786 SNPs using the Affymetrix SNP Array 6.0 chips in Korean. In the replication, direct genotyping was performed using 3052 cases and 4976 controls from the KItaNagoya Genome study of Japan with 14 selected SNPs. To maximize the coverage of the genome, imputation was performed based on 1000 Genome JPT+CHB and 5.1 million SNPs were retained. CAD association was replicated for three GWAS-identified loci (1p13.3/SORT1 (rs599839), 9p21.3/CDKN2A/2B (rs4977574), and 11q22.3/ PDGFD (rs974819)) in Koreans. From GWAS and a replication, SNP rs3782889 showed a strong association (combined P=3.95 10(-14)), although the association of SNP rs3782889 doesn't remain statistically significant after adjusting for SNP rs11066015 (proxy SNP with BRAP (r(2)=1)). But new possible CAD-associated variant was observed for rs9508025 (FLT1), even though its statistical significance did marginally reach at the genome-wide a significance level (combined P=6.07 10(-7)). This study shows that three CAD susceptibility loci, which were previously identified in European can be directly replicated in Koreans and also provides additional evidences implicating suggestive loci as risk variants for CAD in East Asian.</P>
JY Park,AR Kim,SY Yoo,JI Kim,TW Jung,SH Woo,HY Heo,TW Kim,TS Ko 한국육종학회 2013 한국육종학회 심포지엄 Vol.2013 No.07
Excessive water stress can cause severe damage to sorghum and results in significant yield reduction. The aim of this study is to identify quantitative trait loci (QTL) for excessive water stress in sorghum. As a first step, two out of 21 bmr mutants were selected for their superior agronomic performance and Chlorophyll a fluorescence OJIP transient, and were crossed with an elite Korean cultivar, Hwangkeumchal, to construct mapping populations. One hundred ten out of 236 SSR primers showed polymorphism between two parens, which cover ten chromosomes of sorghum from different published SSR linkage maps of sorghum. Development of recombinant inbred lines from the crosses ‘25M2-0698 x Hwangkeumchal’ and ‘25M2-0404 x Hwangkeumchal’ are in progress using the single seed descendent method for generation acceleration.
JY Park,AR Kim,SY Yoo,JI Kim,TW Jung,SH Woo,HY Heo,TW Kim,TS Ko 한국육종학회 2013 한국육종학회 심포지엄 Vol.2013 No.07
Grain sorghum is the fifth most important crop grown in the world for either a major food crop or animal feed. It is important to identify the genetic diversity of sorghum genetic resources for cultivar development and evaluation of sorghum accessions in Korea. Two hundred thirty six SSR primer sets, which are evely distributed across the sorghum genome, were used to assess the genetic variation of 23 sorghum accessions with a US cultivar, BTx623. Results showed that SSR markers were highly polymorphic among the sorghum collections and the average alleles per locus were 3.15 with the average of 0.436 PIC (polymorphism information content) values. The sorghum accessions in this study were unequally separated and were clustered into 4 groups. The results showed that there was a sufficient SSR polymorphism with SSR primers used among Korean sorghum accessions, and the development of genetic map and marker-assisted selection for cultivated sorghum would be feasible with further studies.
MLVA Genotyping of Brucella abortus isolated from cattle in Korea
Jin-Ju Lee(Jin-Ju Lee),Eun-Ji Yum(Eun-Ji Yum),Eun-Ji Park(Eun-Ji Park),Min-Kyeong Kim(Min-Kyeong Kim),Min-Hoe Lee(Min-Hoe Lee),So-Ra Sung(So-Ra Sung),Hee-Soo Lee(Hee-Soo Lee),Bang-Hun Hyun(Bang-Hun Hy 한국예방수의학회 2019 한국예방수의학회 학술대회자료집 Vol.2018 No.-
이헌영,남궁성은,김수평,한구택,유기성,신재인,강창석,심상인 대한산부인과학회 1994 Obstetrics & Gynecology Science Vol.37 No.12
저자들은 자궁경부암 조기진단 센터를 방문하여 질확대경진과 조준 조직생검을 시행받은 환자들을 대상으로 질확대경진 점수에 의한 추정진단이 동시에 실시한 조직진에 의하여 일치된 소견을 나타내는지를 알아보았던 바 다음과 같은 결론을 얻었다. 1. 질확대경진 점수가 0-2점으로 불현성 인간유두종 바이러스 감염으로 진단한 경우 조직진이 양성우종성 변화인 경우는 94.66% 였고, 6-8점으로 CIN III이상으로 진단된 경우 조직진이 교란 조직 성숙형으로 나타난 경우는 60.71%였으며 3-5점으로 CIN I-II로 진단된 경우 추정 바이러스성 부정형이나 비정상 세포 표현형을 나타낸 경우는 모두 58.07%(각각 48.39%와 9.68%)였다. 2. 질확대경진 점수가 0-2점으로부터 6-8점으로 점차 증가함에 따라 조직학적 변화가 양성 우종성 변화로부터 교란조직 성숙혀으로 점차적인 악성화를 나타내었다. (P=0.0001). 3. 질확대경진 점수가 0-2점일 때 불현성 인간 유두종 바이러스 감염의 진단은 민감도가 90.5%, 특이도가 94.95%였고 양성 및 음성예측도는 94.7%와 90.0%였다. 점수가 6-8점으로 CIN III이상으로 진단된 경우는 민감도가 78.2% 특이도는 94.4% 양성 및 음성 예측도는 97.5%와 60.7%로 나타냈다. 이상의 결과로서 질확대경진시에 질확대경진 지표에 따른 점수의 산정에 의한 추정진단은 조직학적 진단의 지표와 관련시켜 보았을 때 매우 일치하는 결과를 관찰하였으며 질학대경진 관찰자의 숙련이 필요하고 임상병리 의사의 질확대경진 소견 및 인간유두종 바이러스 감염에 대한 인식이 증가되어야 할 것으로 생각되며 질학대경진의 적절한 이용은 자궁경 병변의 조기진단과 이에 대한 적절한 관리로 우리나라에서 발생율이 높은 자궁경암에 의한 생존율을 증가시킬 것이며 아울러 인간유두종 바이러스 감염과 자궁경암과의 관련은 이에 대한 기초 연구가 더 진행되어야 할것으로 생각된다. Colposcopic signs demarcation, surface contour, color change and abnormal vessels of the cervical lesions of two hundreds and seventry four patients , who were enteredinto this study, were graded into three objective categories representing subclinical papillomaviral infection, CIN I-II and CIN III and/or above by scoring. These were evaluated by histopathologic findigns of benign warty change, presumed viral atypia, abnormal cell phenotype and distubed tissue maturation to evaluate the accuracy of this colposcopic differentiation between the different histologic grades of lesins by scoring. In this study, we used the modified colposcopic indices excluding the Lugol`s iodine statining. The lesoins with mirror colposcopic signs, which were scored below 2, were attrbutable to humal papillomaviral disturbanced fo cell growth and amturation, which were seen histologically as parabasal layer proliferation, papillomatosis, koilocytosis, and dyskeratosis. Major colposcopic abnormalities, which were scored 6and/or avove, reflect extensive disorganization of cell phenotype and tissue architecrue. Intermediate colposcopic patterns, which had scores between 3 and 5, generally denote the reciprocal tissue changes of a comosite of the benign warty expression and the premalignant change. We also observed that a highly significant statistical realtionship exists between subclinical papillomaviral infection and the occurrence of cervial neoplasia correlated by colposcopic signs and histologic indices (X2= 268.29, p=0.0001). In the colposcopic diagnosis for subclinical papillomaviral infection, we obseved that the sensitivity and specificity were 90.5% and 94.95% and the positive and negative predicive value were 94.7% and 90.9% respectively. The sensitivity and specificity for CIN III and/or above were 78.2% and 94.4% and the positive and negative predictive value were 78.2 and 94.4% and the positive and negative predictive value were 97.5% and 60.7% respectively. These results suggest that the colposcopic scoring is very useful for the diagnosis and differentiation of the various cervical lesion.