대전광역시 월평공원과 전북 격포해수욕장 주변 야생화와 토양들로부터 야생효모의 분리 및 국내 미기록 효모들의 특성과 생리 활성

장지은 ( Ji-eun Jang ),박선정 ( Seon-jeong Park ),이종수 ( Jong-soo Lee ) 한국균학회 2021 韓國菌學會誌 Vol.49 No.1

많은 사람들이 다녀가는 도시공원과 해변 환경의 효모 특성을 알아보기 위해 대전광역시 월평공원 갑천 누리길과 내원사 주변의 야생화와 토양 75점에서 모두 88균주의 야생 효모들을 분리, 동정하였다. 또한 전북 부안의 격포해수욕장과 격포항 주변 야생화와 토양 35점에서 30균주의 야생 효모들을 분리하였다. 이들 분리 야생 효모들 중A. porosum ASCM32-1, A. scarabaeorum WP49-1, C. athensensis WP4-90-3, C. berkhoutiae WP34-2, C. bracarensis WP35-1, Cy. amylophila GP19-1, K. gamospora WP9-1, M. carpophila BN-17-1, T. namnaoensis WP4-89-1, V. taibaiensis WP13-2 등 10종의 국내 미기록종 후보 균주들을 선별하여 균학적 특성을 확인하였다. 이들 미기록 효모들은 주로 구형~타원형으로 모두 출아방식으로 영양 증식을 하였고V. taibaiensis WP13-2와 K. gamospora WP9-1, C. athensensis WP4-90-3 외 7종의 미기록 효모들은 자낭포자를 형성하지 않은 무포자 효모들이었으며A. porosum ASCM32-1만이 의균사를 생성하였다. 대부분의 균주들은 YPD 배지와 YM 배지에서 생육하였고V. taibaiensis WP13-2와K. gamospora WP9-1, T. namnaoensis WP4-89-1 균주들은 15% NaCl을 함유한 YPD 배지에서 생육하는 호염성 효모들이었고, Cy. amylophila GP19-1 균주는 40˚C에서도 생육하였다. C. athensensis WP4-90-3 균주 등 5균주들이 10% 에탄올 내성을 보였고C. athensensis WP4-90-3 균주는 Li²⁺ 등 많은 중금속들에 대해서 내성을 보였다. 국내 미기록 효모들과 비병원성 야생 효모 균주 무세포추출물들의 β-glucuronidase 저해 활성은 C. oleophila WP5-19-1의 무세포 추출물이 49.0%로 가장 높았고 미기록 효모인K. gamospora WP9-1의 무세포 추출물도 27.7%를 보였다. 호중구 elastase 저해 활성은W. anomalus HO9-2가 38.4%로 우수하여 건강 소재로 생산에 매우 유용한 균주로 활용될 것으로 기대된다. This study aimed to isolate wild yeasts obtained from flowers and soil of the Wolpyung park, Daejeon city and Gykpo beach, Buan, Jeollabuk-do in Korea, and to further characterize previously unrecorded wild yeast strains. In total, 88 strains of 62 different species of wild yeasts were isolated from 75 samples obtained from the Wolpyung park. Among these, six strains of Trichosporon moniliiforme and four strains each of Papiliotrema flavescens and Candida melibiosica were isolated. Additionally, 39 strains of 30 different species of wild yeasts were isolated from 35 samples collected from the Gykpo beach. Among the 127 isolated wild yeast strains, 10 strains, including Apiotrichum porosum ASCM32-1, were previously unrecorded. All the 10 previously unrecorded yeasts were oval or global in shape, and three strains, including Candida athensensis WP4-90-3, formed spores. Three strains, including Vishniacozyma taibaiensis WP13-2, were halophilic yeasts which grew in 15% NaCl-containing YPD(yeast extract-peptone-dextrose) medium. Five strains, including C. athensensis WP4-90-3, showed 15% ethanol resistance. Cell-free extracts from Candida oleophila WP5-19-1 and Wickerhamomyces anomalus HO9-2 showed the highest β-glucuronidase inhibitory activity (49.0%) and neutrophil elastase inhibitory activity (38.4%), respectively.

박인환 시의 불안, 죽음 의식과 이를 통한 시쓰기의 문제

박지은(Park, Ji-Eun) 한국시학회 2018 한국시학연구 Vol.- No.55

이 연구는 박인환 시에 나타나는 불안과 죽음 의식에 대해 논의한다. 또한 박인환 시에서 나타나는 불안과 죽음 의식이 단순하게 비극적 시대 상황에 처한 지식인의 수동적인 감정이 아니라, 그가 역사를 인식하는 데 보다 근본적인 역할을 하는 중요한 ‘기분’(Stimmung)임을 밝히고자 하였다. 나아가 이 과정을 통해 박인환 시에서 주로 등장하는 모티프들(검은 신, 바람/폭풍, 종말 등)을 해석하고, 박인환 시를 깊이 있게 이해하는 한 지점을 마련하고자 했다. 그의 문학 전반을 관통하고 있는 불안과 죽음 의식은 단순히 한국전쟁이라는 특정한 원인에 국한되는 것이 아니다. 그의 시에서 불안은 오히려 세계 속에 ‘내던져져 있음’(Geworfenheit)에 의한 존재론적 불안에 가깝다. 그는 이러한 존재론적 불안을 ‘바람’(폭풍)의 이미지로 표현하고 있으며, 그에게 인식되는 무의미의 세계는 ‘검은 신’의 이미지로 나타난다. 존재론적인 불안의 문제는 죽음 의식과도 연관된다. 그는 언제나 자신을 삶과 죽음 사이에 위치한 존재로 위치시키는데, 이 때 그에게 죽음은 곧 닥쳐올 어떤 것이면서 동시에 그로 하여금 현재의 삶을 계속 자각하게 하는 것이다. 그에게 죽음을 인식하는 시간은 자신이 처한 현재를 객관적으로 바라보게 하는 ‘순간’이 된다는 것이 그의 죽음 의식의 특징적인 부분이다. 결국 그가 불안과 죽음 의식을 통해 얻게 된 것은 양심으로서의 시쓰기이다. 화자는 불안 속에서 들려진 양심의 부름을 듣고, 그는 본래적인 자기(시인이 되기)를 회복하려는 노력을 계속한다. 이렇게 봤을 때 불안과 죽음에 대한인식은 시인이 시쓰기를 계속할 수 있는 동력이 된다. 즉 박인환의 문학에서 ‘불안’은 단순하게 전쟁으로 인한 수동적인 감정을 표현하는 것이 아니며, 오히려 그의 시작(詩作) 전체를 추동시키는 근본적인 요인으로 기능하였다는 것을 알 수 있다. 박인환은 자신의 문학을 통해 특정한 시대를 뛰어 넘는 진정한 실존의 의미에 대해 질문했다. 또한 불안이라는 감정에 잠식되는 것에서 나아가 자신만의 독특한 죽음 의식과 양심의 문제를 보여주었다. This study discusses Park, In-hwan’s attitude toward death and anxiety as they appear in his poetry. I argue that the anxiety and consciousness of death that appears in Park’s poetry is not simply the passive emotional response of an intellectual facing a tragic era, but is instead an important mood(stimmung) that serves a more fundamental role in Park’s perception of history. Through this process, I interpret some of the main motifs of Park’s work (the black god, wind/storms, finality, and so on), hoping to provide a perspective from which to understand Park’s poetry with greater depth. The source of the anxiety and consciousness of death that permeates Park’s work is not limited simply to the Korean War. The anxiety of his poetry is instead closer to the ontological anxiety of “having-been-thrown” (geworfenheit) into the world. He expresses this ontological anxiety through the image of ‘wind’ (or storms), and he represents a perceived world of meaninglessness in the image of ‘the black god.’ The issue of ontological anxiety is also linked to his consciousness of death. Park consistently locates himself in the space between life and death, so that to him death is both something fast approaching and, at the same time, the thing that repeatedly makes him aware of life. The discerning feature of this consciousness of death is that the moment the poet perceives death is the moment that forces him to see his present objectively. Ultimately what Park achieves through this consciousness of death is a poetry of conscience. From within his anxiety, the speaker hears the call of conscience, and then makes a continued effort to recover his essential self (to become a poet). In this way, anxiety and perception of death become the motivation for the poet to continue writing poetry. In other words, it can be seen that in Park’s work, anxiety is not only the expression of a passive emotional response to war, but in fact functions as the fundamental element that sets his entire poetic process in motion. Park thereby approaches the question of the real meaning of existence, which extends beyond a specific era, in his literary work. In addition, he moves beyond the encroachments of anxiety as an emotion to reveal a unique attitude towards death and the problem of conscience.

요대(遼代) 선연(鮮演)에 수용된 법장(法藏)의 화엄사상

박은영(지현)(Park, Eun-Young (Ven. Ji-Hyun)) 동국대학교 불교문화연구원 2018 佛敎學報 Vol.0 No.85

중세 동아시아의 화엄사상은 법장에 의해 대성되고, 징관에 의해 혁신을 거듭한다. 당대(唐代)에 확립된 화엄교학은 이후 북송(北宋)에서는 법장의 화엄학이 중시되었던 반면에, 같은 시기에 요대(遼代)에서는 특히 징관의 화엄학이 중점적으로 연구된다. 따라서 요대에는 법장이 큰 연관이 없는 것 같지만 사실은 요대 화엄학 저술인 선연의 『담현결택기』6권속에서 법장의 사상은 충실히 수용되고 있다. 징관의 『대소』와 『연의초』가 법장을 종지로 받들어 지어진 것이고, 『결택기』가 그것의 주석서인 점에서 볼 때, 『결택기』에는 그 자체로 법장의 사상이 녹아들어 있다고 할 수 있다. 실제 『결택기』에 인용된 문헌 중에는 법장의 저술인 『교의분제장』이 가장 많이 인용되었고, 또 다른 저술인 『지귀』, 『탐현기』, 『기신론의기』도 직접 · 간접적으로 인용되었으며, 선연은 매우 빈번하게 ‘현수의 뜻’을 회통하고 있다. 내용적으로는 『현담』 본문의 제1장 「교장소섭(藏敎所攝)」과 제2장 「의리분제(義理分齊)」부분에서 많이 인용되었는데, 특히 일승과 삼승의 불일불이(不一不異), 동교일승 ․ 별교일승, 5교교판과 십현문 등 화엄일승원교의 의리를 밝히는 데 있어 주요쟁점들을 선연이 법장의 사상을 통해 적극 활용하고 있는 것에서 잘 드러난다. 본 논고에서는 『결택기』에 인용된 법장의 저술과 그 구체적인 내용을 중심으로 해서 선연이 법장의 사상에서 무엇을 강조하고 있고, 석성하고 있는 내용은 무엇인지를 중점적으로 살펴서 선연에게 수용된 법장의 화엄사상을 살펴봄으로써 요대 화엄사상속에서 법장 화엄사상의 위상을 파악하고자 한다. Chinese Buddhism and especially Huayan thought flourished in the Liao dynasty 遼(916-1125) and was based on Chinese translations of Buddhist literature made during the Tang dynasty 唐 (618-907). Huayan Jing Tǎnxuan Juezĕ Ji, written by Xianyǎn 鮮演(1040-1118), was one of the later annotations to the Xuant-1 玄談 from the 20 volumes of Dafang’guangfo Huayan Jing Shu 大方廣佛華嚴經疏 and the 40 volumes of Suishuyanyi Chao 隨疏演義鈔, which was widely known as a distinctive commentary on the 80 volumes of the Avataṃsaka sutra written by Qingliang Chengguan 淸涼 澄觀 (738-839). Juezĕ Ji was annotated for Xuantan 玄談 in a very clear and accurate tone, as the way in which Xianyǎn’s opinions were absorbed in the writing of Chengguan did not include notes or as water permeating into any objects. We are able to see that Juezĕ Ji was annotated in Xianyǎn’s own unique way, which made Chengguan’s writings clear and obvious. Additionally, Juezĕ Ji frequently quoted classic literature, Fa-Tsang 法藏 (643-712) wrote and the number of quotes ranged from twos to score every fascicle. Thus, it can be said that the same way as Xianyǎn was absorbed in Chengguan’s writing, the essence of the Huayan thought of Fa-Tsang was accepted by Xianyǎn from the Liao period in Juezĕ Ji.

Development of a Mobile Application, "Wild Flowers of Bukhansan National Park (version 1.0)", for Identification of Plants in Bukhansan National Park

Kim, Sang-Tae,Lee, Seung-Yeon,Kim, Seung-Chul,Byun, Hye-Won,Lee, Sang-Tae,Kim, Mu-Yeal,Hong, Seok-Pyo,Chung, Young-Jae,Park, Ki-Ryong,Lee, Chung-Hee,Lee, Joong-Ku,Heo, Kyeong-In,Lee, Ji-Ye,Lee, Eun-Je National Science Museum of Korea 2011 Journal of Korean nature Vol.4 No.3

We developed the educational purpose mobile application, named "Wild Flowers of Bukhansan National Park (version 1.0)", aiming for easy identification of wild flowers for students and visitors in the park. When visitors find a flower or part of plant in the park, visitors can search for its name utilizing the pictures and characters provided in their own smartphone mobile devices or tablet PCs. The application provides pictures of wild flowers in the park and character-based searching system based on 12 diagnostic features (e.g., growth form, leaf arrangement, flower symmetry, petal color, petal number, sepal number, etc). We adopted the complete floristic survey of Chung and Lee (1962) and added species that we confirmed their distribution in the park during the development of this application. In summary, number of vascular plants in this park was estimated to be 428 taxa including 100 families, 280 genera, 327 species, 1 subspecies, 50 varieties, and 5 formas. We provided a total of 588 pictures representing 358 taxa and each taxon includes multiple pictures in many cases. Included identification quizzes can be an efficient educational tool as well as fun activity for students and visitors who are learning plant species in Korea. Our next step will include GPS function in the application for indicating visitor's location and for providing previously reported sites of the species that we interested in the map of the park. The future application which includes GPS function will be a valuable tool for the monitoring of rare plants, plant researches related to the climate changes, etc. We currently provide Korean iPhone version only, and English version and both of android versions will be serviced soon.

정상임신 산모와 중증자간전증 산모의 혈소판지수 비교

박용범,한지수,정동근,이인식,김암,민원기,지현숙,목정은 울산대학교 의과대학 1993 울산의대학술지 Vol.2 No.1

The purpose of this retrospective study was to define platelet indices in severe preeclampsia(N=98) and to compare them to normal nonpregnant values(N=93) during the years 1990-1993 in the Department of Obstetrics and Gynecology, College of medicine, University of Ulsan, Asan Medical Center. Indices evaluated included platelet count, mean platelet volume, and platelet distribution width. Means platelet volume was statistically different between two groups, however mean platelet count was significantly decreased(p=0.029) and platelet distribution width was significantly increased(p=0.0001) and platelet distribution width was significantly increased(p=0.0001) in severe preeclampria. Mean platelet volume versus platelet count in normal pregnancy showed a significant inverse nonlinear relationship(r=-0.39, 9<0.001) and that in preeclampsia was congruent with notmal nonpregnant valus. With same mean platelet volume, platelet distribution width showed tendency to shift to right in severe preeclampsia. These findings support the concept of severe preeclampsia as a compensated state of increased platelet comsumption comparing with normal pregnancy. We concluded from above results that quantification of platelet indices may have some value in screening for and following severe preeclampsia.

Impact of the oxygen functional group of nitric acid‑treated activated carbon on KOH activation reaction

Ji‑Hyun Kim,Sang Youp Hwang,Jung Eun Park,Gi Bbum Lee,Ho Kim,Seokhwi Kim,Bum Ui Hong 한국탄소학회 2019 Carbon Letters Vol.29 No.3

To prepare activated carbon with a high specific surface area, oxygen functional groups (OFGs) that can serve as useful electron donors during KOH activation were treated with nitric acid and incorporated into activated carbon. OFGs are incorporated differently according to the surface characteristics of starting materials. Up to 22.46% OFGs are incorporated into wood-based activated carbons (WACs), the C=O, COOH contents was 1.90, 17.05%, respectively. Whereas up to 12.82% OFGs are incorporated into coconut shell-based activated carbons, the C=O, COOH contents was 4.12, 6.15%, respectively. The OFGs used for increasing the specific surface area are the carbonyl group, and as the content of the functional group increases, the carbonyl group spreads to the carboxyl group. The specific surface area of activated carbons increased by 10–68% with an increase in the carbonyl group up to 6% (maximum point of carbonyl group). On the other hand, the specific surface area for WACs increased when the carboxyl group was 10% or below, but decreased by 6–15% when it increased to 10% or excess.

내시경적 조임근절개술후에 발생한 췌십이지장 가성동맥류 1예

박수영,김윤정,박진한,전현수,박시형,이영진,이은지,김지현 仁濟大學校 白病院 2010 仁濟醫學 Vol.31 No.-

We reported a case of pancreatic pseudoaneurysm, involving pancreaticoduodenal artery, developed after endoscopic retrograde cholangiopancreatography(ERCP) with endoscopic sphinterotomy. A 54 year old woman was transferred to our hospital due to sustained hematochezia and hypovolemia. A week before admission, she underwent ERCP with endoscopic sphinterotomy for acute cholangitis in local clinics. She developed abdominal pain and hematochezia at 12 hours after the procedures. A post procedure contrast enhanced computed tomography of abdomen demonstrated a pseudoaneurysm in inferior portion of pancreatic head. This was not present on the pre procedure contrast enhanced computed tomography of abdomen and was thought to arise from the pancreaticoduodenal artery as a complication of the pre sphincterotomy. She was brought to our emergency room in a state of hypovolemia. A upper endoscopy showed active bleeding from ampula of vater. An celiac angiography demonstrated pancreatic pseudoaneurysm involving inferior pancreaticoduodenal artery and selective coil embolization of was performed.

THE EFFECT OF PRIMING ETCHED DENTIN WITH SOLVENT ON THE MICROTENSILE BOND STRENGTH OF HYDROPHOBIC DENTIN ADHESIVE

박은숙,배지현,김종순,김재훈,이인복,김창근,손호현,조병훈 대한치과보존학회 2009 Restorative Dentistry & Endodontics Vol.34 No.1

장기적인 상아질 접착의 내구성 악화는 접착층과 혼성층의 친수성 부위에서의 가수분해에 의해 일어나는 것으로 보고 되고 있다. 본 연구의 가설은 콜라겐 망상체를 유기용매로 프라이밍하면 콜라겐 조직을 붕괴시키지 않고 수분을 밀어내고 소수성 단량체와 유기용매로 이루어진 접착제가 침투하여 접착강도를 얻을 수 있다는 것이다. 두 소수성 단량체인 Bisphenol-A-glycidylmethacrylate (Bis-GMA)와 triethyleneglycol dimethacrylate (TEGDMA)를 아세톤, 에탄올 또는 메탄올에 용해시켜 세 가지의 실험용 접착제를 준비하였다. 산 부식과 수세과정 후에, 접착제를 습윤 상아질 표면(습윤 접착)이나 동일한 용매로 프라이밍 된 상아질 표면(용매 프라이밍 접착)에 적용하였다. 48시간 후와 1개월 후, 및 10.000회의 열순환 후에 미세인장결합강도를 측정하였다 접착계면은 주사전자현미경을 이용하여 관찰하였다. 접착방법에 무관하게 대부분의 시편의 접착계면예서 잘 발달된 혼성층을 관찰할 수 있었고 가장 높은 평균 미세인장결합강도는 에탄올을 포함하는 접착제의 48시간 후 시편에서 관찰되었다. 용매를 이용하여 프라이밍하는 접착 방법에서는 에탄올이나 메탄올을 포함하는 접착제에서 열순환 후에 미세인장접착강도가 증가하는 경향을 보였다. 그러나 습윤 접착의 경우에는 시효처리 후 미세인장결합강도의 증가가 관찰되지 않았다. 본 연구에서 에탄올을 이용한 상아질 프라이밍으로 우수한 접착력을 얻을 수 있었고. 열순환 후 접착력이 더욱 증가하였다 Deterioration of long-term dentin adhesion durability is thought to occur by hydrolytic degradation within hydrophilic domains of the adhesive and hybrid layers. This study investigated the hypothesis that priming the collagen network with an organic solvent displacc water without collapse and thereby obtain good bond strength with an adhesive made of hydrophobic monomers and organic solvents. Three experimentaladhesives were prepared by dissolving two hydrophobic monomers bisphenol-A-glycidylmethacrylate (Bis-GMA) and triethyleneglycol dimethacrylate (TEGDMA), into acetone, ethanol or methanol. After an entching and rinsing procedure, the adhesives were applied onto either wet dentin surfaces (wet bonding) or dentin .surfaces primed with the same solvent (solvent-primed bonding). Microtensile bond strength (MTBS) was measured at 48 hrs, 1 month and after 10,000 times of thermocycles. The bonded interfaces were evaluated using a scanning electron microscope (SEM) Regardless of bonding protocols, weIl-developed hybrid layers were observed at the bonded interface in most specimens. The highest mean MTBS was observed in the adhesive containing ethanol at 48 hrs. With solvent-primed bonding increased MTBS tendencies were seen with thermocycling in the adhesives containing ethanol or methanol. However in the case of wet bonding, no increase in MTBS was observed with aging.

암 환자의 혈장 Transforming Growth Factor-β1 농도

박병규,하우송,이시은,이수진,박순태,박찬후,전지현,장정순 THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCINE 1999 Journal of biomedical laboratory sciences Vol.5 No.2

한국인의 대표적인 성인 고형 종양인 위암, 간암, 유방암과 소아 백혈병 및 2종의 소아 고형 종양 환자로부터 혈장 transforming growth factor-ß1 (TGF-ß1) 농도를 sandwich ELISA 분석법을 이용해 측정함으로써 TGF-ß1을 이 질환들에 대한 새로운 종양표지자 (tumor marker)로 사용할 수 있는지 검토하였다. 또한 연령 및 성별에 따른 혈장 TGF-ß1 농도의 정상치를 조사하였다. 신생아에서 70대까지 혈장 TGF-ß1 농도의 차이는 없었고 남녀간의 차이도 없었다. 위암 환자의 혈장TCF-ß1 농도는 16.0±6.8 ng/ml (평균 ±표준편차)로 정상 대조군의 TGF-ß1 농도 (8.3 ±5.0 ng/ml) 보다 유의하게 높았으나 간암, 유방암 환자의 혈장 TGF-ß1 농도는 대조군과 차이가 없었다. 그리고 위암 환자 16명, 간암 환자 8명, 유방암 환자 7명 중 각각 7명 (43.7%), 1명 (12.5%), 1명 (14.3%)에서만 혈장 TGF-ß1 농도가 증가되었다. 5명의 소아 백혈병 환자에서는 관해 (remission) 여부와 상관없이 혈장 TGF-ßl 농도가 모두 정상 범위에 있었으나 2명의 소아 고형암 환자에서는 종양 절제 전에는 혈장TGF-ß1 농도가 높았다가 절제 후 정상으로 떨어졌다. 결론적으로 1)정상인의 혈장 TGF-ßl 농도는 연령 및 성별에 따른 차이가 없다는 것을 알 수 있었고, 2)성인 고형암인 위암, 간암, 유방암에서는 낮은 민감도로 인해 TGF-ß1을 진단을 위한 선별 검사로 이용하기에는 부적절한 것으로 판단되었으며, 3) 정상 대조군보다 혈장 TGF-ß1 농도가 높았던 위암 환자와 종양 절제 전후로 혈장 TGF-ß1 농도가 민감하게 변했던 소아 고형 암 환자에 대해서는 향후 표본 수를 늘려 부가적인 연구를 해 야 할 것으로 사료된다. To evaluate the usefulness of transforming growth factor-ß1 (TGF-ß1)as a new tumor marker, we determined the plasma TGF-ß1 levels using sandwich ELISA assay in cancer patients. Patients with three most common adult cancers in Korea (stomach, liver and breast cancer) and children's cancers (leukemia and two kinds of solid tumor) were enrolled for the study. Furthermore, 39 individuals were subjected to age and sex-stratified plasma TGF-ß1 analysis. No statistical difference was demonstrated with respect to age or sex. The mean plasma TGF-ß1 level (16.0 ng/ml) of stomach cancer patients was significantly higher than that (8.3ng/ml) of controls. However, there was no difference among the mean plasma TGF-ß1 levels of liver, breast cancer patients and controls. Seven of 16 patients (43.7%) with stomach cancer, one of 8 (12.5%) with liver cancer, and one of 7 (14.3%) with breast cancer showed higher TGF-ß1 levels compared to controls. Plasma TGF-ß1 concentrations of five leukemic children remained in the normal range regardless of the remission state. In contrast, initial high TGF-ß1 levels from two children with solid tumors returned to normal range on surgical resection of tumors. From the above results, we could conclude that plasma TGF-ß1 levels of apparently healthy individuals seem to be rather constant irrespective of difference in age or sex, and the plasma TGF-ß1 has the limited value as a screening test for the diagnosis of aforementioned adult cancers because of its low sensitivity. Finally, additional studies need to be pursed for the large number of stomach cancer and pediatric solid tumor patients in order to reach a secure conclusion on the usefulness of plasma TGF-ß1 as a tumor marker in these patients.

난치성 측두엽 간질환자의 발작간 뇌파소견

김지언,손은익,김준식,이상도,박영춘 대한신경과학회 1998 대한신경과학회지 Vol.16 No.4