논문 : 「권중화개국원종공신록권」에 대한 일검토 : 權仲和開國原從功臣錄券

金炯秀 한국중세사학회 2004 한국중세사연구 Vol.0 No.16

The purpose of this study is to present "Kwon Jung-Hwa's Merit Subject Document for the Foundation of Joseon Dynasty"(權仲和原從功臣錄券) which was included in "Yung-Ga-Se-Go" (永嘉世稿) edited by Lip-Up-Chung-Sa(立嚴精舍) and compare the characteristics of the Merit Subject Document with those of other merit subjects. The Merit Subject Document(功臣錄券) is a secondary record selected for a collection of writings. In addition, the original form of the Document was damaged because considerable parts of the Document were left out in the process of picking out the contents regarding Kwon, Jung-Hwa. Only 53 lines of the Document currently remain with loss of 118 lines and 11 figures are identified on the Document, which indicates the lowest number among other existing merit subject documents. However, merit subjects selected on the Document were officially most highly ranked figures who haven't been found on the other merit subject documents. The figures kept officially high positions at the end of Goryeo Dynasty and didn't actively involve in Lee, Seong-Gye's political revolution except Cho, Hi-Go(趙希古) and Sim, Deog-Boo(沈德符). Most of the figures were highly regarded as respectable senior subjects at that time. The content of reward for the merit subjects of the Document includes thirty kyeols(結) of land and three servants, which is comparable to the reward for figures recorded on "Jeong, Jin's(鄭津) Merit Subject Document". While the principle of reward identified on "Jeong, Jin's Merit Subject Document" took on the standard for Yun, Bang- Kyeong(尹邦慶), the principle of reward on "Kwon, Jung- Hwa's Merit Subject Document" applied the standard for Kim, Lip Kveon(金立堅). As a result, "Kwon, Jung-Hwa's Merit Subject Document" is invaluable for exhibiting an example of merit subject document for the foundation of Joseon Dynasty.

원위 대퇴골의 고립성 골연골종에서 발생한 속발성 연골 육종 1례 보고

정필현,황장수,강석,김용민,오형호,채동주,김종필 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

연골육종은 비교적 서서히 자라며 늦게 전이하는 악성 연골 종양으로 알려져 있다. 골 연골종에서 발생한 속발성 연골육종은 발생빈도는 드물며 타부위로의 전이가 적고 악성도가 낮은 경우가 많아 적합한 수술적 치료로서 좋은 예후를 보이는 것으로 보고되고 있다. 본 동국대학교 정형외과학 교실에서는 우측 대퇴골 원위부 골간단부에 생긴 고립성 골 연골종에서 이차적으로 발생한 연골육종을 치험한 바 문헌고찰과 함께 보고하는 바이다. A case of Secondary Chondrosarcoma Arising from Solitary Osteochondroma of the Distal Femur Department of Orthopaedic Surgery, College of Medicine, DongGuk University Phil Hyun Chung M.D., Jung Su Hwang M.D., Suk Kang M.D., Yang Mln Kim M.D., Hyung Ho Oh M.D., Dong Ju Chae M.D., Jong Pil Kim M.D. Chondrpsarcoma is a malignant cartilage-forming tumor that grows slowly and metastasis of this tumor occurs in late stage. Secondary chondrosarcomas arising from a solitary osteocartilaginous exostosis are rare and those have a better prognosis than other chondrosarcomas, and they rarely metastasize. We present our experience with a case of secondary chondrpsarcoma arising in solitary osteochondroma of distal metaphysis of right femur with clinical details.

[논문]병렬 유전 알고리즘을 이용한 발전기 기동정지계획

김형수,문경준,박준호 釜山大學校生産技術硏究所 2003 生産技術硏究所論文集 Vol.62 No.-

본 논문에서는 병렬 유전 알고리즘을 이용한 발전기 기동정지계획을 제안한다. 최소 기동 및 정지 시간 등과 같은 다양한 발전기의 제약조건을 만족시키면서 발전기 기동정지계획을 수립하는 문제는 비선형적이며 많은 국부해가 존재하므로 최적해를 탐색하는데 많은 시간이 소요된다. 이러한 문제점을 해결하기 위해 16개 의 프로세서를 가진 병렬 시스템과 이를 이용한 병렬 유전 알고리즘을 제안하였으며, 제안한 방법의 효용성을 검토하기위해 10기 및 26기의 전력계통에 적용하여 시율레이션을 시행하였다. 시율레이션 결과 기존의 방법에 비해 탐색속도를 개선하였고 우수한 해를 구할 수 있었다.

四君子湯에서 甘草의 抗酸化劑로서의 役割

김형환,조수인,이용태,김인락 대한본초학회 1999 大韓本草學會誌 Vol.14 No.2

The immune response is dependent on phagocyte function. When this function is deficient or enhanced, the patient is susceptable to a large variety of disease. Enhanced function results in an over active immune response. This study was carried out to investigate whether water extracts of Sijunzi-Tang and Radix Glycyrrhizae have inhibitory effect of neutrophil superoxide generation and cell injury. Superoxide was generated by rabbit polymorphonuclear leukocytes (neutrophils) stimulated by tert-butylhydroperoxide(t-BHP), and was measured by luminol and its detector chemiluminometer. The inhibitory effect of extracts against t-BHP induced superoxide generation was dose-dependent in the range of 0.1~1% concentrations. Cell injury was estimated by measuring lactate dehydrogenase(LDH), and lipid peroxidation was examined by measuring malondialdehyde(MDA), a product of lipid peroxidation. When rat renal cortical slices were treated I mM t-BHP, water decocted herbs inhibited LDH release from the slices as partially dose depecdent manner. It shows that herbs can reduce cytotoxicity, but over dose can be toxic to the slices. And MDA measurement shows the effect of Sijunzi-Tang and Radix Glycyrrhizae inhibiting cytotoxicity from oxidants, partially depend on preventing lipid peroxidation of cells. HPLC data shows the antioxidative effect of Sijunzi-Tang depends on the effect of Radix Glycyrrhizae. So further studies should be followed to make clear the mechanisms of antioxidative effects.

인간 재조합 인터루긴-32 면역조절작용에 대한 유세포 분석

이광수,김영관,채정일,심정현,김은미,강형식,김수현,윤도영,명평근 충남대학교 생물공학연구소 2006 생물공학연구지 Vol.12 No.-

Xenotransplantation of porcine organs has the potential to overcome the severe shortage of human tissues and organ available for human transplantation. however, it remains various hurdles for clinical xenotransplantation. In pig and mouse xenotransplantation, porcine xenograft evoke a strong cellular rejection response in immunocompetent host and grafts are destroyed within a week. This cellular immune response could involved both T cells and NK cells. A number of groups have shown that human NK cells can recognize and damage porcine endothelial cells. In addition, human T cells can respond to porcine endothelial cells through both direct and indirect mechanisms. Cellular rejection of porcine tissues requires T cells, particularly CD4^(+) cells. A new cytokine recombinant human interleukin-32α,β(IL-32α,β) has a role innate and acquired immune system. In order to investigate the role of recombinant mouse IL-18 and recombinant human IL-32α,β in xenograft rejection, we transplanted the PK(15) cells to C57BL/6 mice with or without intraperitoneal injection of recombinant mouse IL-18 or recombinant human IL-32 α,β. It was analyzed the population of NK cell, T cell and B cell in the C57BL/6 mice transplanted with PK(15) cells and recombinant mouse IL-18 or recombinant human IL-32α,β by flow cytometry analysis. As a result, lymph node and thymus of PK15/IL18, PK15/IL32α and PK15/IL32β injected group were increased to T cell activation population than normal injected groups. CD8^(+) T cells were decreased in lymph node of PK15/IL18, PK15/IL32α and PK15/IL32β injected groups. CD4^(+) T cells were increased in lymph node cell of PK15/IL32α and PK15/IL32β injected group and also, B cell population were increased in lymph node cell and spleen of PK15/IL18, PK15/IL32α and PK15/IL32β injected group. Therefore, we suggest that recombinant mouse IL-18 and recombinant human IL-32α,β suppress xenograft rejection in cellular xenotransplantation.

호텔 고객의 뷔페 메뉴품질 만족도에 관한 연구

최수근,이연정,이진형 한국식생활문화학회 2004 韓國食生活文化學會誌 Vol.19 No.5

This study aims at providing useful information to establish subdivided marketing direction by deriving factors of significant extent and practicable extent of buffet users toward menu quality among super deluxe hotels in Gyeongju, and furthermore aims at presenting implications for efficient management result and sales increase of buffet in the future. The result of positive analysis is as follows. Firstly, in result of analyzing difference between importance and performance of hotel buffet in Gyungju area, importance is much higher than performance. Secondly, respondents consider that the. most important menu of hotel buffet is main dish such as hot food and instant food rather than menu such as beverage, soup and salad. When it comes to attribute of menu quality, it appeared that respondents put highly significant extent on sanitariness of food, freshness of food, flavor of food, and seasonality and variety of menu. Thirdly, oriental instant food is included in the second quadrant of IPA regarding buffet menu which should be intensively managed. And three attributes such as temperature of food, time of changing food, and creativity of menu are included in the second quadrant of IPA graph by attribute of hotel buffet's menu quality. Lastly, in IPA graph by hotel, the following menus of each hotel need to be intensively managed: Oriental instant food of A hotel, Western cold food of B hotel, Oriental instant food, Western instant food, and Oriental dessert of C hotel, and Western porridge·soup, Oriental instant food, and Western instant food of E hotel. The aforementioned menus should be improved.

입력전력제어에 의한 단상유도전동기의 효율개선에 관한 연구

백형래,박수강 조선대학교 에너지.자원신기술연구소 2000 에너지·자원신기술연구소 논문지 Vol.22 No.1

The paper presents a new drive for single-phase induction motor and a one-chip micom-based controller and control method for self-starting and Input power saving of single-phase induction motor driven from a phase angle control is described. The controller is capable of motor operating in the maximum efficiency region as well as in the optimal input power region. The implementation of the microprocessor is based on an 8-bit programmable micro-controller in low cost. The proposed method is based on the optimal efficiency control which is running by variable phase angle of main winding current of single-phase induction motors. The variable phase angle switching strategy more economized for self-starting and phase angle control of the motor than the PWM switching strategy in high cost. The implemented system consists of TRIAC for voltage control, starting capacitor, 8bit one-chip microcontroller for maximum efficiency control. Experiments are focused on a capacitor starting single-phase induction motor, the optimal Input energy saving by variable phase angle control are verified by experimental results. Also, auxiliary winding was controlled by electronic starting switch.

법랑아세포종에서의 p53 및 MIB-1 발현 : 임상 및 병리학적 요인들간의 연관성 Correlation Between Clincopathologic Parameters

이수운,한지용,권창석,윤혜경,김우형,이희철 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.4

Thirty five patinets' paraffin embedded biops block , which was previously diagnosed ameloblastoma and obtained from oral and maxillofacial surgery dept. of pusan paik hospital and OMS dept of collage dentistry, pusan national university hospital, from January 1994 to march 1999, were performed immunohistochemistry with p-53 and MIB-1. On investigating the expression, correlation between clinical and histologic factor and correlation between prognosis and moleculopathologic property were examined. And we obtained the following results; 1. Age over forty, recurrence rate was 58.5%. 91.4% of the tumor was developed on mandibule, recurrence rate of maxilla area tumor was 66.7% On radiologic and histologic feature, multilocular and follicular type has high recurrence rate but no significance statistical difference was found 2. Expression of p-53 was 25.7%, When underage of forty. location on mandibule, multilocular and plexiform type, the expression of p-53 was somewhat higher and recurred cases of tumor, expression rate was 12.5%. 3. MIB-1 expression rate was 77.1%. When location on mandibule, unilocular, plexiform type tumor and previously recurred case, MIB-1 expression was 87.5% which was somewhat higher than no recurrence case of 74.1%. 4. 33.3.% of positive on MIB-1 have expression of p-53 and all p-53 positive case express MIB-1 positive. All p-53 positive case have high cell proliferation rate. From this result, age and location have closely related with the prognosis of tumor, histologic feature and MIB-1 expression has related with the prognosis of tumor. But p-53 has highly expressed on cell proliferation area, not closely related with the prognosis of tumor.

랫드에서 인체 재조합 적혈구 조혈인자, rHuEPO의 13주 정맥투여 아만성독성에 관한 연구

김형식,곽승준,천선아,박현선,한하수,임소영,안미영,김원배,김병문,안병옥,홍성렬,이병무 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

A recombinant human erythropoietin (rHuEPO) was administered intravenously at dosage levels of 0, 100, 500, and 2500 IU/㎏/day for a period of 13 weeks. There were no observed clinical signs and deaths related to treatment in all groups tested. Decreases in body weight gain and food consumption were observed only in males of 2,500 IU/㎏ group after 2 weeks. In hematological parameters, erythrocyte content, hematocrit values and hemoglobin concentration were dose-dependently increased in rHuEPO treated groups. The ratio between kidney weight and whole body weight was significantly increased in females of 500 and 2,500 IU/㎏ groups. The spleen weight was also increased in both sexes of 500 and 2,500 IU/㎏ groups. However, the absolute weight change of other organs was not observed. In histopathological examinations, the renal tubular basophilia was observed only in males and females of 2,500 IU/㎏ groups. From these results, it is concluded that the no-observed adverse effect level(NOAEL) of rHuEPO is 100 IU/㎏ in rats in the present study.

장애인의 생활무용참여에 대한 무용전공인의 인식에 관한 연구

정형수,강선옥,강승애 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.3

The purpose or this study was to investigate of acceptance attitudes of dance majors toward the participation of person with the disabled in dance for all, The methods or this study were used by questionnaires which were distributed to 495 person who are dance instructors and student with Majors in dance from universities, graduate school students. The results of the study were as follows: First, there was an overall acceptance attitude regarding the participation of dance for all by the disabled, Dance for all for the disabled was positively accepted on grounds that it is necessary for health status, improvement of health, rehabilitation and treatment, There was also a positive attitude toward it in terms of confidence and improvement of social adaptability skills, Second, in terms of acceptance attitudes according to majors, Yoga majors most openly accepted it, There was no significant difference in qualifications of educators of dance for all in six sub categories. There was a significant difference, according to dance instructors and dance majors in the category of the effects of dance for all in six sub categories. Third, in terms of acceptance attitudes according to careers, the more career one had, the more positive the attitude one had toward it. Forth, in terms or experiences of teaching the disabled and related work experiences, there was a significant statistical difference in practicality and instructors qualifications among the six sub categories.