Ocular MALT Lymphoma : Report of Two Cases

윤영묵,장효찬,김동석,김상원,박미옥,박재복 대구효성가톨릭대학교 1998 연구논문집 Vol.57 No.2

Lymphoma arising in mucosa-associated lymphoid tissue(MALT) is extranodal marginal zone lymphoma displaying a proliferation of follicle marginal zone-type cells(centrocyte-like cells or monocytoid B-cells), often with surrounding reactive germinal centers and lympoepithelial lesions. This typically expresses pan-B-cell markers and monotypic immunoglobulin but not CD5 or CD10. Ocular MALT consists of the lacrimal gland, lcular soft tissue, orbit, conjunctiva and cornea. Lymphoma arising in thses sites is of very rare occurrence in up to 1.5% of all patients with non-Hodgkin's lymphoma. Herein we report two cases of ocular MALT lymphoma which was very rare in the dermatologic field. Case 1, 73-year-old man, developed the right upper conjunctival swelling measuring about 2.0×2.5cm for about 1 year. Histologically, the excised lesion showed follicular centers and infiltration of centrocyte-like cells of B-cell lineage in the stroma but no lymphoepithelial lesions, consistent with low-grade B-cell lymphoma. Case 2, a 66-year-old female, had a rapid course of about 1.2×1.0cm-sized, soft, wellow mass arising from lacrimal gland of the right upper eyelid for about 1 month. Hostologically, the lesion showed diffuse patterend features admixed with centrocyte-like cells and large cells such as centroblast, compatible with high-grade lymphoma. Case 2 received combined chemotherapy of m-BACOD, with a somewhat improvement.

브랜딩·스타일링·마케팅을 결합한 스페이스 디자인 프로세스 연구 - 작품‘Fill the Red, Feel the Red'를 중심으로 -

은다솜,장효실,최해원,홍지현,이진민,장미정,이성애 숙명여자대학교 디자인연구소 2018 숙명디자인학 연구 Vol.25 No.-

본 연구는 디자인 분야와 마케팅 분야의 전략을 종합하여 전략적 연결점을 찾아내 요소들 간 융합을 이루는 사례를 제시하여 브랜드·스페이스·마케팅에서 새로운 방향성과 아이디어를 제시하는데 목적을 둔다. 이에 본 연구는 2017년 9월~12월까지 ㈜애경과 산업 연계하여 진행된 숙명여대 환경디자인학과 ‘브 랜딩·스타일링·마케팅’ 교과목에서 도출된 ‘fill the red, feel the red’ 프로젝트를 마케팅 및 디자인 프로세스, 결과물을 도출하여 그 과정들을 밝힌다. 아울러 본 연구는 브랜드 스페이스 마케팅에 대한 이론적 고찰을 통해, 브랜드 스페이스(팝업스토어)를 개발 및 스타일링하며 ㈜애경의 화장품 브랜드 ‘LUNA’를 브 랜딩, 스타일, 마케팅적 측면에서 종합적으로 연계하여 도출되는 과정들을 제안함으로서 향후 브랜드 스페이스 디자인과 마케팅 분야에 체계적이고 창의적인 방법들로 결과물을 도출하는데 기초자료로 활용하는데 의의가 있다.

오감(五感)적 요소를 접목한 브랜드 스페이스 연출 계획 -마임 화장품 프레쉬가든을 중심으로-

김소현,임하영,장효실,최혜원,이진민,장미정,이성애 숙명여자대학교 산업디자인연구소 2017 숙명디자인학 연구 Vol.24 No.-

인간이 갖고 있는 감각 기관은 시각, 청각, 후각, 촉각, 미각의 총 다섯 가지로, 이를 모두 활용 할 때 이상적 공간 상호작용이 가능하다. 본 연구는 화장품의 공간 연출 계획 시 오감적 요소를 접목하여 브랜드 이미지를 구축하는 일련의 프로세스를 밝히는데 목적이 있다. 이에 본 연구는 2017년 3월~6월 15주간 숙명여대 환경디자인학과 <융합연출디자인> 수업에서 진행된 수업의 결과물로서 작업물을 정리하였다. 그 결과 본 연구는 제품이나 서비스를 직접 경험할 수 있도록 다양한 엔터테인먼트적 요소를 결합하여 기능적 만족감과 더불어 체험적 만족감 제공하는 오감적 디스플레이를 제안하였다. 본 연구는 오감을 활 용한 뷰티 쇼룸으로 감각을 공간에 어떠한 방식으로 적용할 것인지에 대한 정립을 했다는 데에 의의가 있다. 아울러 다양한 매체와 공간의 개념이 일반화 되어 가는 오늘날 기업 환경 속에서 오감적 체험을 기반으로 한 공간연출은 가상의 공간속에서도 유연하게 적용 가능한 디스플레이 요소로 확인되었다. 또한 본 연구는 향후 이와 관련된 쇼룸 공간 개발에 있어서 기초 자료로 활용될 것으로 기대된다.

Changing Prevalence of Helicobacter pylori Infections in Korean Children with Recurrent Abdominal Pain

Jang, Kyung Mi,Choe, Byung-Ho,Choe, Jae Young,Hong, Suk Jin,Park, Hyo Jung,Chu, Mi Ae,Cho, Seung Man,Kim, Jung Mi The Korean Society of Pediatric Gastroenterology 2015 Pediatric gastroenterology, hepatology & nutrition Vol.18 No.1

Purpose: The aim of this study is to investigate the changing prevalence rate of Helicobacter pylori infection in children, of different age groups, with recurrent abdominal pain over a 10-year period. Methods: Children with recurrent abdominal pain who visited the pediatric outpatient clinic at university hospital were screened for H. pylori. Children were divided into 3 age categories of 4-5, 6-11, and 12-16 years. To study the changes in the annual prevalence rates of H. pylori infection, the study period was divided into 3 time periods: 2004-2007, 2008-2010, and 2011-2014. Urea breath test was performed for all children aged 4-16 years, with a cut-off value of 4.0‰ for children aged ${\geq}6$ years and 7‰ for children aged <6 years. Results: A total of 2,530 children (1,191 boys) with a mean age of $10.0{\pm}3.0years$ (range, 4.0-16.9 years) were included in the study. The total prevalence of H. pylori infection was 7.4% (187/2,530). The prevalence rate of H. pylori infection in children with recurrent abdominal pain was 8.0% (70/873) in 2004-2007, 7.7% (51/666) in 2008-2010, and 6.7% (66/991) in the 2011-2014. Nevertheless, a significant difference was observed in the prevalence rate between children <12 years old and ${\geq}12$ years of age (p=0.018). Conclusion: The prevalence of H. pylori infection in Korean children with recurrent abdominal pain was 7.4%, showing no significant decrease in the last 11 years; however, the prevalence rate in children <12 years old was significantly lower than that in those ${\geq}12$ years old.

Use of insulin detemir in dogs with diabetes mellitus

Hyo-Mi Jang,Na-Young Eom,Yang-Ho Kang,Dong-In Jung 충북대학교 동물의학연구소 2015 Journal of Biomedical and Translational Research Vol.16 No.1

Insulin detemir is a long-acting basal insulin analogue recently introduced in veterinary medicine for treatment of canine diabetes mellitus. As there are only limited studies in dogs, long-term evaluation of insulin detemir in veterinary medicine is required. In this study, we investigated trends in12-hour blood glucose concentration during hospitalization and evaluated initial and following doses of insulin detemir for several months in six diabetic dogs. The mean levels of blood glucose over 12-hour periods were between 113.5 to 327.2 mg/dL, and the average glucose nadir was 103 mg/dL in the six dogs. The dogs were treated with a mean dosage of 0.24 U/kg of insulin detemir, but hypoglycemia was observed in four of the dogs at the first monthly follow-up. Thus, insulin doses were adjusted according to the nadir levels of glucose observed during the follow-up periods (range, 1 to 16 months). The total range of insulin doses throughout the study period was between 0.1 and 0.4 U/kg. Changes in insulin doses in each dog during the follow-up period were not variable. We suggest that insulin detemir might be not only an alternative choice against traditional insulin for patients with insulin resistance or concurrent disease but also an effective home therapy medication in canine patients with DM. This study could help inform veterinary practitioners regarding the use of insulin detemir for canine insulin-dependent DM.

Prevalence of serum allergen-specific immunoglobulin E for canine atopic dermatitis in Korea

Hyo-Mi Jang,Gwi-Seon Yeo,Ji-Hyun Kim,Cheol-Yong Hwang,Jae-Eun Hyun,Soon-Shin Kim,Yang-Ho Kang,Dong-In Jung 충북대학교 동물의학연구소 2014 Journal of Biomedical and Translational Research Vol.15 No.4

Canine atopic dermatitis (CAD) is an allergic skin disease with characteristic clinical features associated with immunoglobulin E (IgE) antibodies. Identification of the causative allergens is the diagnostic goal, which is essential to treat and manage CAD patients. CAD is commonly associated with environmental allergens surrounding the patients. For this reason, it is important for diagnostic tests to select allergens that are related to the environment of each country and each province. There are two main allergen-specific tests, serological IgE test (SAT) and intradermal skin test (IDT). SAT did not show direct cutaneous reaction but did show serological reaction against allergens. However, SAT is simpler and more convenient than IDT in small animal practice. In this study, we selected domestically prevalent allergens for SAT, including 60 food allergens and 60 inhalant allergens, and tested eight dogs tentatively diagnosed with CAD based on Favrot’s criteria. Furthermore, IDT was performed on four dogs from the SAT group for comparison of SAT and IDT, and the results were very similar. In SAT, four types of mites (Bloomia tropicalis, Glycophagus domesticus, Euroglyphus maynei, and mite mixture 1 Korea; house dust mites), four types of molds (Botrytis cinerea, Alternaria alternata, mold fungi mixture 11, mold fungi mixture), and one type of pollen (tree pollen mix 3 Korea) induced a reaction in more than half of dogs tested. In IDT, all four dogs reacted positively to Dermatophagoides farinae, and three reacted positively to Dermatophagoides pteronyssinus and house dust. The mean agreement rate between SAT and IDT in this study was 76.3%. This is the first trial to apply local allergens for SAT in Korean veterinary medicine, and it might play an important role for diagnoses and management of animal allergic diseases.

은행 및 비은행 금융기관 차입금이 기업의 성과에 미치는 영향

장효미(Hyo Mi Jang),전봉걸(Bong Geul Chun) 한국경제통상학회 2015 경제연구 Vol.33 No.2

본 논문은 중소기업을 대상으로 은행 및 비은행금융기관의 차입과 기업의 경영성과 간 관계를 실증분석하였다. 첫째, 당기의 차입으로 분석했을 경우 비은행금융기관 차입에 비해 은행 차입이 기업의 경영 성과에 더 부정적인 영향을 미쳤다. 이는 차입의 과정에 대한 제도적 문제를 고려해 볼 수 있으며, 장기차입금에 대한 이자비용이 리스크로 작용했을 것이라 추론한다. 둘째, 1기전 차입으로 분석했을 경우 비은행은행금융기관의 차입보다 은행 차입이 기업의 경영성과에 더 긍정적인 영향을 미쳤다. 은행 차입의 경우 안정성면에서 기업에게 더 긍정적인 영향을 미치기 때문이라 추론한다. 셋째, 산업별 분석은 전기, 가스, 증기 및 수도사업을 나타내는 산업D와 전문 과학 및 기술 서비스업인 산업M에 대하여 실시하였으며, 앞서 분석하였던 실증분석과 같은 결과를 나타냈다. This Study analyzed relationship between business performance and corporate borrowing targeting small and medium-sized enterprises among the listed companies in Korea. By analyzing corporate borrowing separated to bank loans and non-bank loans, tried to the discussion about "Of the bank loans and non-bank loans, which one have a significant effect on the business performance". Firstly, there was a negative statistical correlation between business performance and corporate borrowing when analyzed by borrowing in the current period. also, Bank loans has had a negative impact on business performance than the non-bank loans. In this case, I infer that the interest cost about long-term bonds and institutional issues such as borrowing process and period is applied to the risk. Secondly, there was a positive statistical correlation between business performance and corporate borrowing when analyzed by borrowing in the previous period. also, Bank loans has had a positive impact on business performance than the non-bank loans. In this case, I infer that companies receive the profits from investment activities and revenue activities through borrowing. It is intended as another example, the safety of bank loans is affected more positive. Finally, In the industry D and industry M, Issued the same conclusions as a result it has been previously analyzed.

Tier2 방법에 따른 온실가스 인벤토리 불확실성 평가: 철강산업을 중심으로

장효미 ( Hyo Mi Jang ),전봉걸 ( Bong Geul Chun ) 경희대학교 사회과학연구원 2015 社會科學硏究 Vol.41 No.3

정밀한 온실가스 배출량을 산출하는 데 있어 국내의 상황은 객관적인 자료가 확보되지 못하는 부분이 존재하며, 측정기의 물리적 한계, 통계관리의 인적 오류 등으로 불확실성 분석이 정확하게 이뤄지지 않고 있다. 따라서 본 논문에서는 철강산업부문의 에너지원 사용에 따른 온실가스 배출량의 불확실성을 전문가 판단 조사 지침을 활용하여 Tier2 수준에서 평가하고자 한다. 전문가 판단 조사방법을 활용하여 에너지원 소비량과 배출계수 및 순발열량의 확률밀도함수를 도출하였으며 조사한 정보를 기반으로 몬테카를로 시뮬레이션을 수행하였다. 분석 결과, 철강산업부문에서 무연탄, 유연탄 및 도시가스의 소비로 인한 이산화탄소 배출량의 불확실성은 95% 유의 수준에서 유연탄 소비량에 삼각분포를 가정하였을 때 20% 수준으로 크게 나타났으며, 균등분포를 가정하였을 때는 8% 수준인 것으로 분석되었다. In domestic situation, there is a lack of objective data that is not ensured in the process of calculating accurate emissions of GHGs. Uncertainty analysis is not performed correctly due to human error of statistics management and physical limitations of the measuring instrument. Therefore, in this study, we evaluate the uncertainty of the GHG emissions in the steel industry by using expert judgement in Tier2 method. We derived the probability density function of the energy consumption, emission factor and net calorific value, and then, performed Monte carlo simulations on the basis of the survey information. The results of the analysis, in 95% confidence interval, uncertainty is around 20% when it is assumed a triangular distribution in flaming coal consumption. Another uncertainty is around 8% when it is assumed a uniform distribution.

청소년지도사의 현재와 미래

변효정(Byeon Hyo Jeong),윤창주(Yun Chang Ju),장남윤(Jang Nam Yun),장윤미(Jang Yun Mi),전수현(Jeon Su Hyeon),전지현(Jeon Ji Hyeon),최희선(Choe Hui Seon),홍성미(Hong Seong Mi) 한국청소년문화연구소 2003 청소년 문화포럼 Vol.8 No.-

A retrospective study for allergic dermatitis in 35 dogs

Dong-In Jung, Hyo-Mi Jang, Byeong-Teck Kang 충북대학교 동물의학연구소 2013 Journal of Biomedical and Translational Research Vol.14 No.4

Allergic disorders are exaggerated immune responses to foreign antigens, regardless of the mechanism, while atopic disorders are exaggerated IgE-mediated immune responses (type I hypersensitivity). Allergic dermatitis is a common pathological condition of skin in humans and dogs. Canine allergic dermatitis presents with clinical signs similar to those reported in humans, and its causes are complex; therefore, diagnostic tests and treatments may need to be adjusted for each patient. Dogs with allergic dermatitis can suffer from secondary infections, which must be considered and confirmed or excluded for successful treatment. In this report, 35 cases of canine allergic dermatitis diagnosed using variable methods, including histological and cytological examination, are described. Patients were treated with oral or topical medications (antimicrobials, anti-inflammatories, immune modulators, topical ointments, and medicated shampoos), and their diets and environmental surroundings were also modified. This report provides an analysis of the breed, gender, age of onset, clinical signs, diagnostic methods, and treatments for canine allergic dermatitis. The information on canine allergic dermatitis presented here could be helpful in the study of human cases because these two species often share living spaces, environments, and lifestyles more closely than other animals. However, previous reports have suggested that human and canine allergies differ in some features, such as involvement of histamine in induction of pruritus, and in histopathological characteristics such as cutaneous structures.