A Systematic Review and Meta-Analysis of Arthroscopic Meniscus Repair in Young Patients: Comparison of All-Inside and Inside-Out Suture Techniques

Dong­Geun Kang,Young­Jin Park,Jae­Ha Yu,Jong­Byung Oh,Dong-Yeong Lee 대한슬관절학회 2019 대한슬관절학회지 Vol.31 No.1

Purpose: The purposes of the present study were to review published studies that investigated arthroscopic meniscus repair to treat meniscus injury in young patients and to compare all­inside and inside­out suture techniques.Methods: Various electronic databases were queried for published articles, and this search was updated in August 2017 for evaluating the outcomes of arthroscopic meniscus surgery in young patients. Data search, extraction, analysis, and quality assessment were performed according to the Cochrane Collaboration guidelines, and the clinical outcomes were evaluated using various outcome values in young patients according to suture techniques.Results: Three randomized controlled trials and three prospective comparative studies were included in this systematic review and meta­analysis. There were no significant differences in clinical outcomes such as meniscus healing rate (risk ratio [RR], 1.11; 95% confidence interval [CI], 0.90 to 1.37; I2=39%) and perioperative complications (RR, 0.62; 95% CI, 0.23 to 1.72; I2=43%) between all­inside and inside­out techniques for meniscus repair.Conclusions: The present study shows favorable results for clinical outcomes such as meniscus healing rate and perioperative complications in young patients. Furthermore, based on our results, both all­inside and inside­out meniscal suture techniques are equally effective in these patients.

NR과 SBR 가황물의 경도와 강성도에 대한 온도의 영향

진현호 ( Hyun Ho Jin ),홍창국 ( Chang Kook Hong ),조동련 ( Dong Lyun Cho ),강신영 ( Shin Young Kaang ) 한국고무학회 2007 엘라스토머 및 콤포지트 Vol.42 No.3

본 연구에서는 고무제품의 수치 안정성과 성능유지에 직접적으로 영향을 미치는 중요한 특성 중 하나인 온도변화에 따른 고무재료의 경도변화를 고찰하였다. 새롭게 제작된 International Rubber Hardness Degree(IRHD, Normal type) 경도측정 시험기를 사용하여 미충전된 NR과 SBR시편의 여러 온도에서 경도변화를 측정하였으며 Young`s modulus 값과 비교하였다. NR과 SBR 모두 유리전이온도 근처에서 경도와 Young`s modulus의 급격한 변화를 보였다. 온도가 증가함에 따라 경도와 Young`s modulus 값이 증가하는 경향을 보였으며 이는 분자의 운동성과 엔트로피 영향으로 해석할 수 있다. 카본블랙과 실리카가 충전된 NR과 SBR의 경우 충전제의 함량이 증가함에 따라 경도에 미치는 온도의 영향이 감소함을 관찰하였다. Hardness of rubbery materials, which is important for dimensional stability and product performance, was investigated upon temperature change in this study. A newly developed IRHD (International Rubber Hardness Degree) tester was used to measure the hardness changes of NR and SBR specimens at various temperatures and the hardness values were compared with the Young`s modulus. The hardness and Young`s modulus of NR and SBR showed an abrupt change near the glass transition temperatures. The hardness and Young`s modulus were increased by increasing temperature due to the increased random chain conformation of molecules. The effect of temperature on hardness and Young`s modulus of NR and SBR specimens filled with carbon black and silica was decreased by increasing filler content.

Elderly kidney transplant recipients have favorable outcomes but increased infection-related mortality

임정훈,Lee Ga Young,Jeon Yena,Jung Hee-Yeon,Choi Ji Young,CHO, JANG-HEE,Park Sun Hee,김용림,Kim Hyung-Kee,Huh Seung,유은상,Won Dong Il,Kim Chan-Duck 대한신장학회 2022 Kidney Research and Clinical Practice Vol.41 No.3

Background: The number of elderly patients with end-stage kidney disease has been increasing, but the outcomes of kidney transplants (KT) remain poorly understood in elderly patients. Therefore, we evaluated the clinical outcomes of elderly KT recipients and analyzed the impact of elderly donors. Methods: This retrospective cohort study included patients who underwent KT between 2000 and 2019. KT recipients were divided into four groups according to a combination of recipient and donor age (≥60 or <60 years); elderly recipients: old-to-old (n = 46) and young-to-old (n = 83); young recipients: old-to-young (n = 98) and young-to-young (n = 796). We compared the risks of mortality, graft failure, and acute rejection between groups using Cox regression analysis. Results: The incidence of delayed graft function, graft failure, and acute rejection was not different among groups. Annual mean tacrolimus trough level was not lower in elderly recipients than young recipients during 10-year follow-up. Mortality was significantly higher in elderly recipients (p = 0.001), particularly infection-related mortality (p < 0.001). In multivariable Cox regression analysis, old-toold and young-to-old groups had increased risk of mortality (adjusted hazard ratio [aHR], 2.89; 95% confidence interval [CI], 1.14– 7.32; p = 0.03; aHR, 3.06; 95% CI, 1.51–6.20; p = 0.002). However, graft failure and acute rejection risks were not increased in elderly recipients. Conclusion: In elderly recipients, graft survival and acute rejection-free survival were not inferior to those of young recipients. However, mortality, especially risk of infection-related death, was increased in elderly recipients. Thus, low immunosuppression intensity might help decrease mortality in elderly recipients.

동씨침을 시술한 안면경련의 치험 3례

김태우,김효은,조명제,강영화,이재동,Kim, Tae-woo,Kim, Hyo-eun,Cho, Myung-je,Kang, Young-hwa,Lee, Jae-dong 대한침구의학회 2003 대한침구의학회지 Vol.20 No.1

Objective : Hemifacial spasm is painless uncommon disorder characterized by involuntary paroxysmal movement of one side of face, In this study, the effect of Dong-Si acupuncture therapy for three patients with hemifacial spasm were evaluated. Methods : We have treated them with acupuncture treatment of Dong-Si acupuncture points(Cheuk-Samni and Cheuk-ha-Samni) and evaluated the effect by Scott's scale, For the first two weeks, it was dine once a day, and after two weeks, the other day. Results : Before therapy, the grades of spasm intensity classified by Scott's description in three cases were 3. And after Dong-Si acupuncture therapy, the grade of one case was 0, and two cases were 1. Conclusion : The Dong-Si acupuncture therapy for hemifacial spasm was effective and will be attempted to the patients with it.

1920년대 경성(京城)의 역사(歷史)/인문자원(人文資源) 아카이브 구축(構築)의 사례(事例) -『경성백승(京城百勝)』을 중심으로-

유춘동(兪春東) ( Yoo Choon-dong ),오영식(吳榮植) ( Oh Young-sik ) 한국어문교육연구회 2020 어문연구(語文硏究) Vol.48 No.4

『경성백승』은 1924년 6월 25일부터 8월 16일까지 <東亞日報> 문화면에 게재되었던 ‘一百洞町, 一百名物, 내 동리 名物’ 연재물을 재정리하여, 1929년 10월에 동아일보사 출판부에서 단행본으로 출간한 것이다. 1910년에서부터 1920년대 사이에는 朝鮮半島 전역을 다룬 案內書나, 국내주요 도시의 도시 안내서가 많이 출간되었다. 특히 경성의 지역 안내서는 타 도시와 비교해 볼 때 압도적으로 많았는데, 『경성백승』은 이 책들과 여러 면에서 차이가 있다. 이 책은 발간 및 기획주체가 宋鎭禹, 洪命熹, 鄭寅普 등의 민족지도자가 참여했고, 무엇보다 경성의 역사/인문자원의 원고를 당시 경성에 거주하면서 동아일보를 구독했던 독자들이 작성했다는 점에서 구분된다. 즉, 『경성백승』은 다른 경성 안내서와 다르게 ‘조선인에 의해서, 조선인이 선별한 경성의 주요 역사/인문자원이라는 것이다. 이 글에서는 이러한 『경성백승』의 전반적인 내용과 특성, 이 책에 수록된 1920년대 경성의 역사/인문자원의 아카이브의 특징 및 활용 방안에 대해서 살펴보았다. In this article, we looked at the character of “Gyeongseong Baekseung” published by the Dong-A Ilbo in 1929 and the meaning of this book. This book was published in October 1929 by the Dong-A Ilbo Publishing House, summarizing the series published in the Dong-A Ilbo culture section from June 25 to August 16, 1924 Between 1910 and 1920, guidebooks on the entire Joseon Peninsula and city guides for major cities in Korea, Gyeongseong, Busan, Daegu, Pyongyang and Kaesong, were published in a flurry. Among them, the number of 'regional guides' for Gyeongseong is overwhelming compared to other cities. However, “Gyeongseong Baekseung” differs from these books in many ways. Most of the “Gyeongseong Guidebook” and “Regional Guidebook” published during this period were published by the Governor-General of Joseon or published by related organizations. However, the book was organized by the Dong-A Ilbo, which was recognized as a national newspaper at the time, participated in the publication process by national leaders such as Song Jin-woo, Hong Myung-hee and Jeong In-bo, and most of all, it was written by readers who subscribed to the Dong-A Ilbo while living in Gyeongseong. In other words, “Gyeongseong Baekseung” is distinguished in that it is the main historical/human resources of Gyeongseong selected by the Joseon people, unlike other Gyeongseong guides. This article examines the overall contents and characteristics of the “Gyeongseong Baekseung” with these characteristics, and focuses on the characteristics of the 1920s Gyeongseong’s historical/human resources archives in the book, and how to study and utilize them in the future, and intends to proceed with the discussion.

혈우병 소견을 가진 뇌출혈 환자 치험(治驗) 1례(例)

정인태,서병관,이현종,하지영,강미경,홍장무,백용현,박동석,최도영,Jung, In-tae,Seo, Byung-kwan,Lee, Hyun-jong,Ha, Ji-young,Kang, Mi-kyeong,Hong, Jang-moo,Baek, Yong-hyeon,Park, Dong-suk,Choi, Do-young 대한침구의학회 2003 대한침구의학회지 Vol.20 No.4

Objective : Hemophilia, a genetically determined disorder, is characterized by abnormality of the coagulation mechanism due to functional deficiency of a specific factor, namely VIII or IX. In this study, the effect of Dong-Si acupuncture therapy on the cerebral hemorrhage patient with hemophilia was evaluated. Methods : We treated him with acupuncture by stimulating Dong-Si acupuncture point(Yuk Wan) and assessed the effect by using manual dynamic evaluation of MRC(Medical Research Council) and Modified Barthel Index. Results : After treatment, the bleeding tendency was grossly reduced and bleeding lesion was absorbed gradually. And manual dynamic evaluation of the upper extremity increased from 4 grade to 5 grade. Conclusions : This result suggest that Dong-Si acupuncture therapy on the cerebral hemorrhage patient with hemophilia was effective. And futher studies are required to concretely prove the effectiveness of Dong-Si acupuncture therapy for treating hemorrhagic diseases.

영골(靈骨).강압혈(降壓穴) 자극(刺鍼)이 혈압(血壓)에 미치는 영향(影向)

임영남,심성용,한지완,고호연,박종형,한양희,전찬용,김동우,Yim, Young-Nam,Sim, Sung-Yong,Han, Ji-Wan,Ko, Ho-Yeon,Park, Chong-Hyeong,Han, Yang-Hee,Chun, Chan-Yong,Kim, Dong-Woo 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.2

Objective : The purpose of this study is to evaluate the clinical effect of the non-pharmacological anti-hypertension method, acupuncture, for hypertensive patients. Methods : 26 patients diagnosed with hypertension were each treated by one of three methods: an anti-hypertension drug(adalat soft capsule), venepuncture, and acupuncture. In cases of rising blood pressure, patients were treated by their one of the three methods, and blood pressure was measured at regular intervals. Result : As for the group of acupuncture treated patients on Young-gol(ling-gu) and Gang-ap-hyul(jiang-ya-xue), readings dropped 18.0mmHg in systolic blood pressure and 6.50mmHg in diastolic blood pressure. This was a greater effect than that seen in the venepuncture treated patients. Blood pressure checked one hour after acupuncture treatment showed a greater difference than blood pressure checked after thirty minutes. Conclusion : Safe reductions in blood pressure were observed through the non-pharmacological method of acupuncture on Young-gol(ling-gu) and Gang-ap-hyul(Jiang-ya-xue).

원인 없는 열로 입원한 생후 28일에서 90일 사이 영아들에 대한 임상적 고찰

류민혁,노윤일,이성훈,이선영,허남진,이동진,Rye, Min Hyuk,Noh, Yn Il,Lee, Seong Hun,Lee, Sun Young,Hur, Nam Jin,Lee, Dong Jin 대한소아감염학회 2001 Pediatric Infection and Vaccine Vol.8 No.2

목 적 : 최근 3개월 이하의 열이 나는 영아에서 특정 임상 경과나 검사실 소견으로 확인된 일부의 환자들은 심각한 세균 감염에 대해 저위험군에 속하며 이들은 외래 치료가 가능할 수도 있다고 한다. 본원 소아과에서는 원인 없이 열이 나는 생후 28일에서 90일 사이의 어린 영아들은 패혈증 의심하에 입원하여 세균성 원인이 아니라는 것이 밝혀질 때까지는 항생제를 투여하였다. 지난 1년 동안 원인 없이 열이 나서 입원 치료한 이 연령군의 영아들을 임상적으로 분석하여 앞으로 치료 방향에 도움을 얻고자 본 연구를 시행하였다. 방 법 : 2000년 1월부터 2000년 12월까지 울산동강병원 소아과에 원인 없이 열이 나서(직장 체온${\geq}38^{\circ}C$) 패혈증 의심하에 입원 치료하였던 131례를 대상으로 성별분포, 계절분포, 원인질환, 발열기간 등을 후향적으로 검토하였다. 또한, 심각한 세균감염증에 대한 저위험군의 환아를 식별하기 위해 흔히 사용되는 기준인 개선된 Rochester criteria를 이용하여 대상환아들을 분석하였다. 결 과 : 대상 환아 131례 중 요로감염이 60례(45.8%)로서 가장 많았고, 무균성 뇌막염이 33례(25.2%), 균혈증 2례(1.5%), 특별한 진단명을 붙일 수 없는 예가 36례(27.5%)였다. 균혈증 2례의 원인균은 Staphylococcus aureus였다. Rochester criteria의 저위험군에 속하는 예가 57례(43.5%), 그렇지 않은 군에 속하는 예가 74례(56.5%)였으며, 요로감염은 저위험군, 그렇지 않은 군은 각각 43.8%, 47.3%, 무균성 뇌막염이 각각 28.1%, 23.0%, 특별한 진단명을 붙일 수 없는 예가 각각 28.1%, 27.0%로서 두 군간의 차이가 없어 Rochester criteria가 본 연구대상 환아들에게는 이들 질환을 구별할 수 있다는 결론을 얻지 못했다. 2례의 균혈증은 모두 저위험군이 아닌 군에 속해 있었다. 남아 85례, 여아 46례로서 남녀비가 1.8 : 1이였고, Rochester criteria에 의한 저위험군과 그렇지 않은 군의 남녀비는 1.9 : 1, 1.8 : 1오서 두 군간의 차이는 없었다. 봄철과 여름철에 각각 35.1%, 36.7% 발생하여 대다수를 차지하였고 무균성 뇌막염은 봄철 16례(48.5%), 여름철 13례(39.4%), 겨울철 4례(12.1%) 발생하였는데, 봄철에 발생한 환아 중 12례는 5월에, 여름철에 발생한 13례 중 12례는 6월에 발생하여 5월과 6월에 대부분 발생하였다. 항생제 투여 후 발열이 소실되는 기간이 48시간 이내에 61.8%, 72시간 이내가 83.2%로서 48~72시간 이내에 대부분의 열이 소실되었으며, Rochester criteria에 의한 저위험군과 그렇지 않은 군의 비교시 48시간 이내가 각각 54.4%, 67.6%, 72시간 이내가 각각 78.9%, 86.5%로서 두군간의 차이는 없었다. 결 론 : 생후 28일에서 90일 사이의 원인 없이 열이 나는 어린 영아는 철저한 이학적 검사와 검사실 소견으로 저위험군에 속하는 경우 보호자가 잘 돌볼 능력이 있고 의사와 연락이 잘 되는 경우 외래 치료가 가능하겠으며, 소변 배양 검사는 채뇨백보다는 도뇨관 채뇨법이나 방광 천자로서 채취한 소변으로 검사를 실시해야 하겠다. 향후 좀 더 바람직한 치료방침을 정하기 위해서 전향적인 연구가 꼭 필요할 것으로 사료된다. Purpose : The purpose of this study was to investigate clinical features of hospitalized infants 28~90 days of age with fever without source and to analyze those of young febrile infants using risk criteria for serious bacterial infection. Methods : The clinical features of 131 infants 28~90 days of age admitted to the Ulsan Dong-Kang General Hospital Pediatric Department because of fever(temperature ${\geq}38^{\circ}C$ rectally) without source, from January 2000 to December 2000, were investigated by retrospective chart review. The clinical features of 131 febrile infants were analyzed using Rochester criteria. Results : Among 131 cases, there were 60 cases(45.8%) of urinary tract infection, 33 cases (25.2%) of aseptic meningitis, 2 cases(1.5%) of bacteremia and 36 cases(27.5%) of no specific diagnosis. Among 131 cases, there were 57 cases(43.5%) in low risk group and 74 cases(56.5%) in not low risk one by Rochester criteria. A significant difference in the incidence of urinary tract infection, aseptic meningitis and no specific diagnosis was not found between both groups. Male to female ratio was 1.8 : 1. Sex ratio between both groups was not significantly different. Most febrile infant were noted in spring(35.1%) and the summer(36.7%). The peak incidence of aseptic meningitis was noted in May and June. The fever subsided mostly within 48~72 hours after administering antimicrobial agents(61.8~83.2%). A significant difference in duration of fever after administering antimicrobial agents was not found between both groups. Conclusion : A selected group of low risk infants 28~90 days of age with fever without source can be managed as outpatients provided that a thorough initial evaluation is performed, that parents can reliably monitor their infant closely at home and that careful follow up can be assured. Because bag collected specimens were more likely to yield indeterminate urine culture result, a suprapubic or catheter obtained urine specimen for culture is a necessary part of the evaluation of all febrile infants 28~90 days of age. The further prospective study on evaluation and management of young febrile infant should be performed in our hospital.

심산 차영배의 삼위일체론에 대한 연구

이동영 ( Dong Young Lee ) 한국복음주의조직신학회 2021 조직신학연구 Vol.38 No.-

본 논문의 목적은 한국 교회 안에서 삼위일체론에 대한 올바른 이해와 전수를 위하여 평생을 노력했던 개혁주의 조직신학자 심산 차영배의 삼위일체론을 분석하고 평가해 보는데 있다. 차영배는 삼위일체론을 기독교 신론의 일부가 아니라 신론 그 자체이며, 단지 신론이 아니라 ‘신학의 본질적 원리’(principium essendi )라고 천명했다. 차영배는 자신의 저서 『개혁교의학. 삼위일체론』에서 교리사적이고 신조학적인 연구를 통하여 삼위일체교리에 대한 자신의 견해를 개진하였다. 특히 『웨스트민스터 신앙고백서』 2장 3절에 대한 자신의 해석에서 우리는 삼위일체론에 대한 차영배의 이해의 정수와 만나게 된다. 차영배에 따르면 『웨스트민스터 신앙고백서』(1648)의 삼위일체론이 삼위를 먼저 구분하고 삼위가 소유한 동일한 본질을 일체로 파악하고 있다고 해석한다. 그렇게 함으로써 그는 장로교회의 표준문서 가운데 하나인 『웨스트민스터 신앙고백서』의 삼위일체론이 「니케아-콘스탄티노플신경」(381)을 통하여 동방교회와 서방교회가 공동으로 고백하는 공교회의 삼위일체론에 정확하게 부합됨을 논증함으로써, 『웨스트민스터 신앙고백서』의 삼위일체론의 공교회적인 성격을 잘 규명해 주었다는 것은 실로 그의 신학적 기여가 아닐 수 없다. 그러나 그에게도 아쉬운 점은 있다. 차영배가 삼위일체론을 기독교 신론의 일부가 아니라 신론 그 자체이며, 단지 신론이 아니라 신학의 본질적 원리라고 천명했음에도 불구하고 그가 삼위일체론을 신학의 원리로 삼아 교의 각론을 해명하고 해설하는 조직신학을 저술하지 못했다는 것, 그리고 그가 삼위일체론의 올바른 해석과 이해에만 집중한 나머지 우리의 신앙 및 삶과 관련하여 이 교리가 함의하고 있는 실천적인 의미를 규명해 주지 못했다는 것은 실로 아쉬운 일이 아닐 수 없다. 그러므로 이러한 조직신학 책의 저술은 차영배의 어깨 위에서서 계속해서 발전해 나가야만 하는 후학들의 몫으로 남아 있다. The purpose of this paper is to analyze and evaluate a Reformed Systematic Theologian Young-Bae Cha’s understanding of the Trinity, which has worked for its correct understanding and transfer within the Korean Church. He declares that the doctrine of Trinity is not part of the Christian doctrine of God, but the doctrine itself, and that this doctrine is not just the doctrine of God but the essential principle (principium essendi) of theology. In his book, “Reformed Dogmatics: doctrine of the Trinity ,” he developed his own view of doctrine of the Trinity through doctrine-historical and creed-historical studies. In particular, in his own interpretation of “the Westminster Confession of Faith 2, 3,” we encounter the essence of his deep understanding of the Trinity. According to him, the doctrine of Trinity in “The Westminster Confession of Faith”(1648) distinguishes tree Persons first and then regards the same essence(ομοουσιος. consubstantia) possessed by three persons, namely the Father, the Son and the Holy Spirit as unity (unitas). By doing so, he demonstrates that the Trinity of “The Westminster Confession of Faith,” one of the standard documents of the Presbyterian Church, is in accord with the doctrine of Trinity of the catholic church jointly confessed by the Eastern and Western Churches through “The Nicaeno-Constantinopolitanum”(381). It is indeed his theological contribution that he well identified the ecumenical character of the Trinity of “The Westminster Confession of Faith.” However, there is the following disappointment to him. 1) First, he failed to write a systematic theology that uses the doctrine of Trinity as a principle of theology to explain and explain another doctrines. 2) Second, he failed to elucidate the practical implications of this doctrine in relation to our faith and life, because he focuses only on its correct interpretation and understanding. Therefore his successors must continue to develop on his shoulders, that they may overcome speculation of the doctrine of Trinity.

니세틸 정(아세틸-엘-카르니틴 500 mg)에 대한 뉴로세틸 정의 생물학적 동등성

조혜영,김은아,정현철,심영순,임동구,오인준,문재동,이용복 전남대학교 약품개발연구소 2001 약품개발연구지 Vol.10 No.-

Acetyl-L-carnitine (ALC), an endogenous component of the L-carnitine family, is naturally occurring molecule synthesized from L-carnitine (LC) by carnitine acetyl transferase. ALC has been shown to improve the cognitive performance of patients suffering from dementia of the Alzheimer's type and proposed for treating Alzheimer's disease in pharmacological doses. The purpose of the present study was to evaluate the bioequivalence of two ALC tablets, Nicetiler^TM (Dong-A pharmaceutical Co., Ltd.) and Neurocetil^TM (Kyung-Dong Pharmaceutical Co., Ltd.), according to the guidelines of Korea Food and Drug Administration. Twenty six normal male volunteers, 22.80±2.76 year in age and 63.07 7.98㎏ in body weight, were divided into two groups and a randomized 2×2 cross-over study was employed. After one tablet containing 500㎎ of ALC was orally administered, blood was taken at predetermined time intervals and the concentrations of ALC in serum were determined using HPLC with fluorescence detector. Because of the presence of endogenous ALC, the calibration was performed using dialyzed serum. Pharmacokinetic parameters such as AUC_t, C_max and T_max were calculated and ANOVA was utilized for the statistical analysis of the parameters. The results showed that the differences in AUC_t, C_max and T_max between two tablets were 2.72%, -0.65% and -8.42%, respectively, when calculated against the Nicetile^TM tablet. The powers (1-β) for AUC_t and C_max were 94.87% and 87.17%, respectively. Minimum detectable differences (Δ) at α=0.05 and 1-β=0.8 were less than 20% (e.g., 15.58% and 19.16% AUC_t and C_max, respectively). The 90% confidence intervals were within ±20% (e.g., -11.84∼6.41 and -10.57∼11.88 for AUC_t and C_max, respectively). Two parameters met the criteria of KFDA for bioequivalence, indicating that Neurocetil^TM tablet is bioequivalent to Nicetile^TM tablet.