국내 다기관에서 조사한 지역사회획득 메티실린내성 황색포도알균의 빈도와 임상적 특성

송진수,최평균,송경호,조재현,김성한,방지환,이창섭,박경화,박경운,신수,최희정,김의석,김동민,이미숙,박완범,김남중,오명돈,김의종,김홍빈,최강원 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

목적 : 최근 전세계적으로 지역사회획득 메티실린내성 황색포도알균(community-associated methicillin-resistant Staphylococcus aureus, CA-MRSA)의 보고가 증가하고 있다. 하지만, 우리나라에서는 CA-MRSA 감염증에 대한 증례보고만 있을 뿐 아직까지 체계적인 연구결과가 없는 실정이다. 저자들은 국내에서 CA-MRSA의 빈도, 감염증의 임상적 양상, 분리된 균주의 항균제내성 양상을 조사하였다. 재료 및 방법 : 2005년 1월부터 2005년 6월까지 7개 병원에서 MRSA가 분리된 환자의 명단을 파악한 후 의무기록지와 건강보험심사평가원의 자료를 검토하였다. 외래나 응급실에서 혹은 입원 후 72시간 이내에 균주가 분리되고 MRSA 획득과 관련된 위험인자가 없는 경우 CA-MRSA로 정의하였으며, 분리된 균주의 임상적 의미에 따라 원인병원체(pathogen), 집락화(colonizer), 미결정(undetermined)으로 분류하였다. Penicillin과 oxacillin을 제외하고 3개 이상의 다른 계열 항균제에 내성이면 다제내성으로 정의하였다. 결과 : 연구기간동안 총 3,251주의 황색포도알균이 분리되었으며, 이 중 MRSA는 1,900주(58.4%)였다. MRSA 가운데 CA-MRSA는 114주(6.0%) 였으며, 이들이 분리된 부위는 귀(62주), 비뇨기계(14주), 피부 및 연부조직(11주), 호흡기계(10주), 혈액(3주) 등이었다. CA-MRSA 균주 가운데 집락균은 22주, 원인병원체는 22주였으며, 나머지 균주에 대해서는 그 임상적 의미를 결정할 수 없었다. 항균제 감수성 검사를 시행한 73균주 중 47주(64.4%)는 다제내성이었다. CA-MRSA 감염증 22예 중 피부 및 연부조직 감염(9예)과 중이염/외이도염(9예)이 가장 흔하였다. 침습적 감염증(invasive infection)은 4명(원발성 균혈증 3예, 감염성 관절염 1예)에서 확인되었지만, CA-MRSA 감염증으로 사망한 환자는 없었다. 결론 : 병원내 감염증에서는 MRSA가 심각한 문제이지만, 아직까지 지역사회 감염증에서 CA-MRSA는 흔하지 않았다. Background : Methicillin-resistant Staphylococcus aureus (MRSA) infection has emerged in patients who do not have the established risk factors. In Korea, little is known about the epidemiology and clinical features of community-associated MRSA (CA-MRSA). Material and Methods : Clinical microbiology laboratory databases of 7 hospitals were reviewed to identify the patients from whom MRSA was isolated during the period of January to July 2005. Only one isolate per patient was enrolled. In order to identify the risk factors of MRSA acquisition, the medical records and the Health Insurance Review Agency databases were reviewed. CA-MRSA was defined as MRSA isolated from patient without established risk factors. We analyzed patient demographics, underlying medical conditions, characteristics of infection, and antimicrobial susceptibility profiles. Results : Of total 3,251 S. aureus isolates, 1900 (58.4%) were MRSAs. Of the MRSA isolates, 114 (6.0%) were CA-MRSA. Of 114 CA-MRSA isolates, 22 (19.3%) were colonizers, 22 (19.3%) were pathogens, and the clinical significance of remaining 70 (61.4%) could not be determined. Median age of the 22 patients with CA-MRSA disease was 47 years. Nine patients had skin and soft tissue infections, 9 ear infections, 3 bacteremia, 1 septic arthritis. Seven patients had underlying medical disease. None died of the CA-MRSA infections. Of the 73 isolates of CA-MRSA, 47 (64.4%) were resistant to more than 3 classes of antibiotics besides β-lactams. Conclusion : Although MRSA is highly prevalent among hospital-associated S. aureus infection, CA-MRSA infections are not common.

중합효소연쇄반응 기법을 이용한 돼지 증식성 장염 진단 기법의 확립

김대영,권언혜,송민동,양시용 建國大學校 自然科學硏究所 2002 建國自然科學硏究誌 Vol.13 No.1

This study was carried out to establish a efficient diagnosis method of pocine proliferative enteropathy (PPE) contributing major economic loss by inducing weight loss, poor growth and/or sudden death through out the growth period(6~22 wk). Therefore, in this study we established the PCR (polymerase chain reaction) which was a fast, specific and sensitive method for identification of Lawsonia intracellularis (L. intracellularis). We designed and synthesized primer on the 16S rDNA and p78 gene encoding L. intracellularis. Specificity of the method was confirmed by comparison of the PCR results using other enteric bacteria and the study has shown that PCR method was sensitive to detect lng of genomic DNA as a template. Also, the PCR method was applicable to the naturally affected pigs with PPE. Based on the results from this study, the PCR method could be used as a fast and specific dignistic tool for PPE.

적외선 열화상 카메라를 이용한 머시닝 센터 주축 열변위에 관한 열해석

김재열,윤성운,임노빈,유신,마상동,양동조,송인석 한국공작기계학회 2001 한국공작기계학회 춘계학술대회논문집 Vol.2001 No.-

Diagnosis or measurements using Infrared thermo-image hasn't been available. A quick diagnosis and thermal analysis can be possible when that kind of system is introduced to the investigation of each part. In this study, Infrared Camera, Thermo-vision 900 was used in order to investigate. Infrared Camera usually detects only Infrared wave from the light in order to illustrate the temperature distribution. Infrared diagnosis system can be applied to various field. Also, it is more effective to analyze temperature distribution on the machining center main-axis process.

소득작물 전후작지 적응 극단기성 벼 ‘중모 1032’

손영보,이종희,조준현,이지윤,오성환,송유천,박동수,박노봉,김상열,여운상,남민희,권영업 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.2

에지와 수평 투영을 이용한 차선 및 장애물 검출

장언동(Chang Un-Dong),송영준(Song Young-Jun),김영길(Kim Young-Gil),김동우(Kim Dong-Woo) 한국콘텐츠학회 2004 한국콘텐츠학회 종합학술대회 논문집 Vol.2 No.2

본 논문은 에지와 수평 투영을 이용하여 차선 및 장애물을 검출하는 기법을 제안한다. 제안 방법은 칼라 입력 영상을 그레이 영상으로 바꾼 후, 소벨 변환을 통하여 에지를 검출한다. 에지를 이용하여 차선을 검출한 후 차선의 영역 내에서 수평 투영을 하여 장애물을 검출한다. 실험 결과, 조명의 변화가 심하지 않은 장소에서 차선과 장애물의 검출이 용이함을 확인할 수 있었다. In this paper, we propose the method of lane and obstacle detection using edge and horizontal projection. we convert color image to gray image and detect edge. After lane detection using edge, we detect the obstacle using horizontal projection in the region of lane. The simulation shows that our method is able to detect lane and obstacle in the place of monotonous light.

측면 얼굴 검출을 위한 적응적 영역 분할 기법

송영준(Chang Un-Dong),장언동(Song Young-Jun),김관동(Kim Kwan-Dong) 한국콘텐츠학회 2003 한국콘텐츠학회 종합학술대회 논문집 Vol.1 No.2

칼라 영상에서 측면 얼굴 검출 시 피부색 검출에 의해 얼굴 후보 영역을 결정하고 템플릿 매칭에 의해 최종 얼굴을 확인하는 방법이 있다. Gang Wei는 측면 얼굴의 좌우 템플릿과 hausdorff 방법에 의한 유사도 측정으로 얼굴 영역을 결정하였다. 이때 측면 얼굴은 목 부분이 넓게 퍼져 있는 부분에서 정확도를 높이기 위해 반복 분할 과정을 수행하여 수직 방향으로 3화소 단위로 분할하여 템플릿 매칭을 하였다. 본 논문에서는 측면 얼굴이 좌측 또는 우측 얼굴 중의 하나라는 가정 아래, 일단 피부색에 의한 얼굴 후보 영역을 수직으로 1/2로 분리한 후 좌측은 좌측 후보, 우측은 우측 후보로 가정하여 템플릿 매칭을 하여 좌/우 얼굴을 인식한다. 이는 기존 연구 방식에 비해 적은 분할로 빠른 얼굴 검출을 할 수 있다. There are many kinds of national and international certifications related to computer science and engineering. Such certifications have evolved from a hiring to a screening tool so that not having them may influence one's being viewed as a serious candidate. To achieve higher rate of acquiring such certifications, a list of certifications with matching curriculum is suggested. By studying these related curriculum hard students will have better chance to get such certification.

차영상과 신경망을 이용한 자동차 번호판 지역 문자 인식

송영준 ( Yong-jun Song ),김동우 ( Dong-woo Kim ),김영길 ( Young-gil Kim ),장언동 ( Un-dong Chang ),권동진 ( Dong-jin Kwon ),안재형 ( Jae-hyeong Ahn ) 한국정보처리학회 2007 한국정보처리학회 학술대회논문집 Vol.14 No.1

자동차 번호판 인식은 카메라의 발달과 무인자동차 주차 시스템, 불법 주정차 단속 등 응용 서비스의 증가로 부각되고 있는 텔레매틱스 분야의 핵심 기술이다. 특히 우리나라의 번호판은 영업용과 비영업용의 도색이 틀리고, 현재 4종류의 번호판 체계를 갖고 있다. 따라서 번호판 인식은 이들 번호판을 종류별로 분류하고 인식해야 되는 어려움이 있다. 본 논문은 레이블링 기법으로 번호판 종류를 분류하고, 지역 글자 인식에서 뭉개짐 현상이 발생하는 경우, 기존의 신경망에서 인식치 못하는 것을 차영상과 신경망을 이용하여 인식률 향상을 이루었다.

Agronomic and Chemical Properties of a New Black Waxy Giant Embryo Mutant, Milyang 263, in Rice (Oryza sativa L.)

Dong-Soo Park,Soo-Kwon Park,Gi Hwan Yi,Un-Ha Hwang,Sang-Min Kim,Sang-Ik Han,Woo Duck Seo,Jong-Hee Lee,Jun-Hyun Cho,You-Chun Song,Un-Sang Yeo,Ki-Chang Jang,Taek-Min Kwon,Min-Hee Nam,Sung-Tae Park,Hang- 한국육종학회 2010 한국육종학회지 Vol.42 No.5

Rice is a staple food for more than 50% of the world's population. Embryo comprises only 2 to 3% of the weight distribution of the entire pericarp but has higher concentration of vitamins, proteins, and essential fatty acids than the other parts of grains. Moreover, α-tocoperol, γ-oryzanol, phytic acid and γ-aminobutric acid that have nutraceutical value are abundant. Increasing the volume of embryo assures the fortification of nutritional value of rice grain. We developed new black waxy giant embryo rice, Milyang 263 by crossing Josaengheugchal, a black waxy rice variety, and get, a giant embryo mutant generated by tissue culture. The nutrient contents and physical properties of Milyang 263 were compared with several giant embryo mutants and normal embryo rice varieties. Changes in the nutrient properties after germination were also observed. Results indicated that this new black waxy giant embryo rice, Milyang 263, offers a promising source for improving nutritional quality of rice especially anthocyanin, essential minerals, and GABA.

90-Day Inhalation Toxicity of Dimethylamine in F344 Rats

Song, Kyung-Seuk,Park, Kun-Ho,Kim, Jeong-Hyun,Han, Dong-Un,Chae, Chan-Hee,Park, Sung-Jin,Kim, Hyun-Woo,Kim, Jun-Sung,Park, Jin-Hong,Eu, Guk-Joung,Hua, Jin,Cho, Hyun-Sun,Hwang, Soon-Kyung Korean Society of ToxicologyKorea Environmental Mu 2005 Toxicological Research Vol.21 No.2

Dimethylamine (DMA) is a widely used commodity chemical with few toxicity data. Groups of 10 male and female F-344 rats were exposed by inhalation to 0, 5, 10, 20, 40 and 80 ppm of DMA for 6 hrs/day, 5 days/week for 90 days. The changes of body weight, organ weight, hematology, clinical chemistry, and histopathological changes were evaluated after the exposure. As the results, the body weight was significantly decreased at 80 ppm in male and female rats (p<0.05). The absolute lung weight showed no statistically significant changes in any group. In contrast, the relative lung weight significantly increased at 80 ppm in male and female rats (p<0.05). Erythrocytes, mean cell hemoglobin, leukocytes, neutrophil, and platelet numbers were significantly increased in male and female at 40 or 80 ppm of DMA (p<0.05, p<0.01). In addition, the serum values of total protein, urea nitrogen were increased in male and creatine kinase, total protein were increased in female rats at 40 or 80 ppm (p<0.05, p<0.01). Histopathological examinations of the male and female lung samples showed slight hyperplasia and congestion at 80 ppm. Taken together, our study revealed that maximum tolerated dose of DMA would be over 40 ppm.

Sonographic evaluation of bladder wall thickness in women with lower urinary tract dysfunction

( Un Ju Shin ),( Jihye Koh ),( Jiwon Song ),( Soyun Park ),( Eun Joo Park ),( Chung-hoon Kim ),( Sung Hoon Kim ),( Byung Moon Kang ),( Hee Dong Chae ) 대한산부인과학회 2018 Obstetrics & Gynecology Science Vol.61 No.3

Objective To investigate the correlation between bladder wall thickness (BWT) measured by ultrasonography and lower urinary tract dysfunction (LUTD) in patients with lower urinary tract symptoms (LUTS). Methods Forty-eight women with LUTS who underwent urodynamic study and BWT by ultrasonography as outpatients were studied. We assessed LUTS during a medical examination by interview. The thinnest part of the bladder wall was measured by a transabdominal ultrasonography. We excluded patients who had visited another hospital previously because we did not know what treatment they had received, including medications, behavioral therapy, or other treatments. We constructed receiver operating characteristic (ROC) curves for diagnosis of LUTD and also determined reliable BWT criteria by calculating the area under the curve. Statistical analyses were performed using the Kolmogorov-Smirnov method and Student's t-test. Results The mean age, body mass index, and duration of symptoms were 59.9±9.7 years, 26.06±3.4 kg/㎡, and 53.4±38.2 months, respectively. Urodynamic study parameters (Valsalva leak point pressure, maximal urethral closure pressure, functional length, and postvoid residual volume) were lower in patients with BWT <3 mm; however, these differences were not significant. Patients with BWT ≥3 mm developed a hypoactive bladder (P=0.009) and intrinsic sphincter deficiency (ISD) (P=0.001) at a significantly higher rate. According to the ROC analysis, the best BWT cut-off value was 3 mm for overactive bladder diagnosis. Conclusion Women with LUTD showed higher BWT values (≥3 mm), especially patients with hypoactive bladder and ISD. Sonographic evaluation of BWT is an easy, fast, and noninvasive method for possible diagnostic tool for LUTD.