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      • 大家畜의 受精卵 移植에 關한 硏究

        李基萬,鄭吉生,高光斗 건국대학교 1982 學術誌 Vol.26 No.2

        This study was carried out in order to induce multiple birth following egg transfer in Korean native cattle, and composed of three experiments ; induction of multiple birth following GTH single administration, Ovarian response to the administration of GTH in combination with Prostaglandin F2α and non-surgical egg transfer following superovulation and non-surgical recovery of fertilized eggs. The results obtained in three experiments were summarized as followings: Experiment I. Induction of multiple birth following GTH single administration. (1) Average duration from PMS administration to the onset of estrus was 3.8 to 4.7 days and no difference due to dosage and administration site of PMS were observed. (2) Duration of induced estrus was ranged from 3.1 to 4.6 days and that of induced estrous cycle was shortened by the length of induced estrus. (3) The most slowed follicles (5.3- 5.5) were observed in the cattle administrated with 2,000 IU of PMS and 1,000 IU of PMS was considered to be the optimum dosage for the limited ovulation. (4) Ovulation rate was declined when the PMS dosage was increased more than, 1000 IU (5) Highest rate of twin birth (35.7%) was obtained from the cattle treated with 1,000 IU of PMS and the next was the catties treated with 500 IU and 2,000 IU of PMS, respectively. Experiment II. Ovarian response to the administration of GTH in combination with Prostaglandin F2α. (1) Average duration from PMS administration to the onset of estrus was 5 days and the duration was shortened with the increasing dosage of PMS. (2) Duration of induced estrus was ranged from 2.3 to 4.5 days and the duration of estrus was shortened with the decreasing dosage of PMS. (3) Number of follicle obtained from the cattle treated with 4,000, 3,000, 2,000, 1,000 and 500 IU of PMS were clarified to be 11.4, 11.5,7,2.3 and 2.5, respectively, after 4.8-5.2 days of PMS administration. (4) Observing the results of slaughter, ovulation rates of the cattle treated with 4,000, 3,000, 2,000, 1,000, and 500 Iu of FMS were 16.3, 35.6, 60.0, 65 and 75%, respectively. (5) The numbers of degenerated, or bled follicle were increased with the increase of PMS dosage. Experiment III. Non-surgical egg transfer following superovulation and non-surgical egg transfer. (1) Average six eggs per donor were ovulated and 65% of them were recovered by non-surgical technique. (2) Eighty two percent of eggs recovered were found to be normal morphologically and were at 4-32 cell stage, respectively. (3) Seventy five percent of cattle treated with prostaglandin F2α were synchronized in their estrus within 4 days of administration. (4) No twin fetation was obtained from the five recipients received fertilized eggs.

      • 환경친화적 도시 마을계획 세부지표 개발에 관한 연구 : 봉화 해저마을과 아산 외암마을 분석을 중심으로 Focused on Haejeo Village with Wae-am Village

        김충래,이광영 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1

        This aims of this study are excavate the environmentally friendly design theories related with the urban village and architecture planning. For this purpose, Normative theory study which means logical analysis of environmentally friendly theories in the new field of environmentally friendly urban village and architectural design, is done in accordance with the object of this study. Site of case study is Haejeo village in Bong-hwa with Wae-am village in Asan. As the result : ① Four-Environmentally friendly urban village planning elements related with the purpose of this study, are clarified : these are social planning, economic planning, education·cultural planning, environmental planning ② Urban village design indicators purposed by means of the normative theory study analysis and contents analysis reated with environmentally friendly urban village and architecture planning which contain environmentally friendly planning elements, and case study.

      • 單獨住宅 外觀의 圖像性에 관한 硏究

        金正在,李光永 慶北大學校 1989 論文集 Vol.47 No.-

        This study intends to clarify the role and the function of the icon in architecture through an examination of role, character and meaning of form as the icon which determine the exterior form of architecture. The object of this study is to clarify the iconology of exterior form of individual house as a question in the society, this time. This study studies how the exterior form of individual house is perceived by poeople in this society and deals with 56 exterior photographs of individual house. Through the opinionsurvey, the respondents are asked to check the like-individual houses as the exterior forms of the "individual house". Before starting this analysis, we set up some items of element which can be drived from the literature on this subject. First, with the question of each item, this study analysis data by cluster analysis. By this analysis, common factor which 56 photographs have can be drived from data as a group. Next, with groups drived from cluster analysis, this study analysis contribute rate for total exterior form of individual house by multi-regression analysis. And then, with analysis result of cluster analysis and multiregression analysis, this study can be clarified the iconology of exterior form of individual house.

      • 高層아파트 主立面 디자인에 관한 硏究 : 視知覺的 측면을 중심으로

        金正在,李光永,姜智秀 경북대학교 산업기술연구소 1991 産業技術硏究誌 Vol.19 No.-

        The aim of this study is to search for correlation of visual experience with the design elements of main facade in high-rise apartment house and their formal characteristics. The main interest is to know how visual experience changes in accordance with the variation of formal characteristics and which formal characteristics have great influence on visual experience in high-rise apartment house.

      • 통풍성 관절염의 임상적 고찰

        윤채중,정승문,김영학,김동규,허광식,김태원,배학연,정종훈,이승일,김평남 朝鮮大學校 附設 醫學硏究所 1997 The Medical Journal of Chosun University Vol.22 No.2

        통풍은 Purine 대사의 이상으로 발생하는 질환으로, 고뇨산혈증인 사람의 전부가 통풍으로 발현되지 않고 증상의 출현 양상이 다양하여 진단과 치료에 주의가 필요하며, 조기에 적절한 조치를 한다면 충분히 조절이 가능한 질환이다. 본대학 내과학교실에서는 통풍으로 치료한 32명의 환자에서 임상양상, 병력과 검사소견을 분석하여 다음과 같음 결과를 얻었다. 1. 32명 모두 남자이며, 최초 발병 시기는 24세에서 72세로 평균 43.8±11.9세이었으며, 30대에서 40대까지가 19명(59.4%)으로 대부분을 차지하였다. 내원 당시 나이는 27세에서 75세까지로 평균 52.3±10.4세였으며, 내원시 까지 평균 유병기간은 8.5±6.8년으로 나타났다. 2. 동반 질환으로는 고지혈증 12례, 신장질환 10례, 고혈압 12례, 비만 8례, 당뇨 2례 등이었다. 3. 이환된 관절은 단관절 침범이 19례(59.4%), 다관절 침범이 13례 이었으며, 최초 이한된 관절은 족무지 중족골지골 관절로 19례(59.4%)로 가장 많았고, 통풍 결절은 20례(62.5%)에서 관찰되었으며, 유병기간이 10년 이상된 12례중 11례 (91.7%)에서 결절이 관찰되었다. 4. 평균 혈중 요산치는 9.17±1.75 ㎎/dl이었으며, 8.0 ㎎/dl에서 9.9 ㎎/dl 사이가 19명으로 전체의 59.4%를 차지하였다. Objective: The gout is a heterogeneous group of diseases resulting from tissue deposition of monosodium urate or uric acid crystals from extracellular fluids supersaturated with respect to this end product of human purine metabolism. The clinical manifestations are such as hyperuricemia, gouty arthritis, gouty nephropathy, uric acid nephrolithiasis. We analyze of clinical manifestations and associated factors in gout. Method: We have reviewed the medical records, radiologic findings and clinical results of thirty-two patients admitted at our department from April 1996 to July 1997. Result: 1) All patients were male. The mean age at initial attack was 43.8 years old, ranging from 24 to 72 years old. 2) The mean level of serum uric acid was 9.17mg/dl on admission. 3) The first metatarsopharyngeal joint was involved in 19 cases (59.4%). Tophus was observed in 20 cases (62.5%). 4) Hyperuricemia was associated with hypertension, obesity, nephrolithiasis and hyperlipidemia.

      • KCI우수등재

        C-반응성단백과 가장 관련 있는 대사증후군 대사이상 항목

        손중천,김범택,이득주,최현국,정현주,김광민 대한비만학회 2003 The Korean journal of obesity Vol.12 No.1

        연구배경: C-반응성단백 (이하 CRP)은 심혈관질환의 예후인자 및 독립적 위험인자이다. 대사증후군은 복부비만, 고혈압. 당대사이상 및, 지질대사이상과 같은 관상동맥질환 위험인자들이 동시에 나타나는 증후군을 말한다. 저자들은 18세 이상의 성인 남녀에서 CRP와 대사증후군 대사이상 항목과의 상관관계를 연구하였다. 방법: 2002년 4월부터 10월까지 일개 대학병원 건강증진센터에 내원한 수진자 2772명 중 염증성질환이 의심되는 577명을 제외한 총 2195명을 대상으로 하였다. 신체계측과 혈압측정, 혈액검사를 실시하였다. 통계적 분석은 남녀를 구분하여 대사증루군의 대사이상 항목의 군집성에 따른 CRP값에 대해 ANOVA 검정을 시행하였고, 각 대사이상 항목들과 연령을 독립변수로 하여 회귀분석을 실시하였다. 결과: CRP는 남성에서 0.10 (±0.004) mg/dL, 여성에서 0.08 (±0.003) mg/dL로 남성이 여성보다 유의하게 높았다(p<0.001). 남녀 모두에서 CRP가 대사증후군 군에서 대사증후군이 없는 군보다 유의하게 높았다. 대사증후군의 대사이상 항목 수가 증가할수록 CRP값이 증가하는 양상을 보였다(P for trend<0.001). 남녀 모두에서 허리둘레 (남성 R²=0.132, 여성 R²=0.166)가 가장 높은 설명력을 보였다. 결론: 18세 이상의 성인 남녀 모두에서 CRP는 대사증후군 대사이상 항목들과 유의한 상관관계를 보였다. 대사이상 항목중 허리둘레가 CRP 수치와 상관관계가 가장 높았다 Background: C-reactive protein has been known as an independent risk factor and prognostic factor for cardiovascular diseases. Metabolic syndrome is a sum of coronary risk factors such as abdominal obesity, elevated blood pressure, hypertension, glucose intolerance and abnormalities in lipid level. The previous studies showed limited relationships between CRP and the risk factors in metabolic syndrome. We investigated the relationships between CRP and the risk factors in metabolic syndrome in adult men and women over 18 years old. Methods: This study included 2772 people. 577 people of them found to have inflammatory disease excluded. The anthropometry and blood pressure were measured. High sensitive CRP, Lipid profiles, WBC, and ESR were assessed. Results: CRP in Men (0.10 (±0.004) mg/dL) was significantly higher than that in women (0.08 (±0.003) mg/dL)(P<0.001). In both genders, CRP was significantly higher in people who have metabolic syndrome than in people who don't. As the number of risk factors increased, CRP was significantly increased (P for trend < 0.001). Waist circumference showed the greatest correlation with CRP in men and women (men; R²=0.132, women; R²=0.166) Conclusion: CRP was correlated with risk factors in metabolic syndrome in men and women over 18 years old. Of the risk factors waist circumference was most correlated with CRP.

      • Multigenerational effects of maternal cigarette smoke exposure during pregnancy on sperm counts of F1 and F2 male offspring

        Lee, Hye Jeong,Choi, Na Young,Park, Yo Seph,Lee, Seung-Won,Bang, Jin Seok,Lee, Yukyeong,Ryu, Jae-Sung,Choi, Seong-Jin,Lee, Sang-Hyub,Kim, Gwang Soo,Chung, Hyun Woo,Ko, Kisung,Lee, Kyuhong,Ko, Kinarm Elsevier 2018 Reproductive toxicology Vol.78 No.-

        <P><B>Abstract</B></P> <P>Animal models and human studies showed that <I>in utero</I> cigarette smoke exposure decreases sperm counts of offspring. This study used a mouse model to investigate the effects of maternal exposure to cigarette smoke on reproductive systems in F1 and F2 male offspring. Female ICR mice were exposed either to clean air or to cigarette smoke during pregnancy at the post-implantation stage. Epididymal sperm counts were decreased in a cigarette smoke dose–dependent manner in F1 (by 40–60%) and F2 males (by 23–40%) at postnatal day 56. In F1, the seminiferous epithelium heights were lower in the cigarette smoke–exposed groups than in the control group, and these effects were sustained in F2 males. Results suggest that maternal cigarette smoke exposure during pregnancy can have a multigenerational adverse effect on sperm counts in male offspring, which is mediated through <I>in utero</I> exposure of fetal germ cells to cigarette smoke.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Maternal cigarette smoke exposure caused low sperm counts of male offspring. </LI> <LI> Seminiferous epithelium heights of male offspring were decreased in the exposed groups. </LI> <LI> Maternal cigarette smoke exposure has a multigenerational adverse effect. </LI> </UL> </P>

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