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Heo, Yunwi,Pyo, Min-Jung,Bae, Seong Kyeong,Lee, Hyunkyoung,Kwon, Young Chul,Kim, Je Hein,Kim, Bokyung,Kim, Choul Goo,Kang, Changkeun,Kim, Euikyung Hindawi Publishing Corporation 2015 Evidence-based Complementary and Alternative Medic Vol.2015 No.-
<P>Bee venom (BV) from honey bee (<I>Apis mellifera L</I>.) has been used in oriental medicine and cosmetic ingredients because of its diverse pharmacological activities. In many studies, among BV components, phospholipase A<SUB>2</SUB> (PLA<SUB>2</SUB>) is known as a major player in BV-induced allergic reaction. Therefore, we removed PLA<SUB>2</SUB> from BV using ultrafiltration and then investigated <I>in vitro</I> phototoxicity and <I>in vivo</I> skin sensitization of PLA<SUB>2</SUB>-free BV (PBV) in comparison with regular BV. The 3T3 neutral red uptake phototoxicity assay can be appropriated to identify the phototoxic effect of a test substance upon the exposure of ultraviolet A. Chlorpromazine, a positive control, showed high levels of photoirritation factor and mean photo effect values, while BV and PBV had less of these values. Local lymph node assay is an alternative method to evaluate skin sensitization potential of chemicals. BALB/c mice were treated with <I>p</I>-phenylenediamine (PPD, positive control), BV, or PBV. In all of PPD concentrations, stimulation indexes (SI) as sensitizing potential of chemicals were ≥1.6, determined to be sensitizer, while SI levels of BV and PBV were below 1.6. Thus, based on these findings, we propose that both BV and PBV are nonphototoxic compounds and nonsensitizers.</P>
Eun-Hoe Goo,Sun-Ju Kim,Kyung-Rae Dong,Kwang-Choul Kim,Woon-Kwan Chung 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.69 No.5
The purpose of this study is to evaluate the image quality in delineation of the portal venous systems with two different methods, breath-hold and non-breath-hold by using the 3D FLASH sequence. We used a 1.5 T system to obtain magnetic resonance(MR)images. Arterial and portal phase 3D FLASH images were obtained with breath-hold after a bolus injection of GD-DOTA. The detection of PVS on the MR angiograms was classified into three grades. First, the angiograms of the breath-hold method showed well the portal vein, the splenic vein and the superior mesenteric vein systems in 13 of 15 patients (86%) and the inferior mesenteric vein system in 6 of 15 patients (40%), Second, MR angiograms of the non-breath-hold method demonstrated the PVS and the SMV in 12 of 15 patients (80%) and the IMV in 5 of 15 patients (33%). Our study showed contrast-enhanced 3D FLASH MR angiography, together with the breath-hold technique, may provide reliable and accurate information on the portal venous system.
증례 : 우상복통을 주소로 내원한 27세 남자에서 대망경색 1예
강현구 ( Hyoun Goo Kang ),이현재 ( Hyun Jai Lee ),이재영 ( Chea Yong Yi ),나경준 ( Gyoung Jun Na ),백현철 ( Hyun Choul Baek ),김정훈 ( Jung Hun Kim ),김상현 ( Sang Hyun Kim ) 대한내과학회 2007 대한내과학회지 Vol.73 No.5
본 증례는 임상소견 및 방사선 소견으로 대망 경색을 진단한 후 보존적 치료를 하였으나, 증상의 강도와 범위가 증가하였으며, 반발압통 및 미열이 지속 되어 대망 경색의 합병증 또는 다른 질환의 가능성을 생각하여 대망 및 충수 돌기 절제술을 시행하였다. 수술 후 통증 및 발열의 호전이 빠르게 나타났으며, 수술 5일째 퇴원하였다. 병리학적 소견에서 대망에 울혈, 출혈 및 지방 괴사의 소견을 보였으며, 그 외 다른 소견은 없었다. 이와 같이 뚜렷한 염증소견 및 위장관 증상 없이 우측 상복부에 국한된 통증이나 압통이 있는 환자의 경우 대망 경색의 가능성을 생각하고 복부 초음파나 복부 전산화 검사로 정확한 진단이 필요하다. 대망 경색의 자연 경과상 일반적으로 약 2주간의 대증 치료만으로 통증 등이 좋아 지는 양성 질환이기는 하나, 환자의 증상이 오히려 심해지는 등의 악화 소견이 있을 경우 다른 추가적인 진단을 위해서 또한 증상의 빠른 호전을 위해 수술적 치료 역시 고려해 보아야 할것으로 생각되어 진다. A rare primary segmental omental infarction in an adult. Infarction of a part of the greater omentum has been recognized as an uncommon condition that may mimic other acute abdominal conditions, particularly acute appendicitis and acute cholecystitis. The presentation and course are seldom typical of appendicitis or cholecystitis. A greater omental infarction may occur without a recognizable cause, and may be termed "primary" (idiopathic), but in some cases, a cause is discovered, such as; mechanical interference with the blood supply to the omentum secondary to torsion, or systemic disorders such as cardiac, vascular, and hematological disease. The inflammatory necrotic mass resulting from the infarction produces somatic pain at its location in the abdomen. For unknown reasons the infarction occurs most commonly in the right half of the abdomen, especially the lower quadrant. An sign of peritoneal irritation, tenderness, and muscle guarding are the principal findings elicited on palpitation of the abdomen. Occasionally, a point of exquisite tenderness may be detected; this usually corresponds to the site of the infarction. Recognizing the typical imaging featuresan ovoid or cake-like mass in the omental fat with surrouding inflammatory changesof this condition is important, as most cases can be managed without surgery. We report a case of an adult patient with acute abdominal pain who was diagnosed with a right-sided segmental omental infarction.(Korean J Med 73:525-529, 2007)