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      • KCI등재후보

        종합검진센터 내원자에서 관상동맥질환 위험요인들의 분포

        이충원,이종영,박종원,윤능기,김영조,이현우,이무식,서석권 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.3

        1991년3월부터 8월사이에 대구시에 소재한 1개의 대학병원의 종합검진센타에 내원해서 종합검진을 받은 남자 422명(69.9%)과 여자 182명(30.1%)을 대상으로 하여 심헐관계질환의 위험요인들의 전체적인 분포를 보았다. 평균 연령은 남자가 43.3(표준편차, 10.3), 여자가 44.4(표준편차, 10.8)였다. 남자에서 연령에 따라 0.05 수준에서 통계적인 유의성을 보인 위험인자는 혈청 총콜레스테롤(TC). 트리글리세라이드(TC), 고밀도 지단백콜레스테롤(HDL), 저밀도 지단백콜레스테롤(LDL), 수축기혈압, 비체중, A형행동양상이었으며 생활습관으로서는 음주, 흡연, 규칙적인 운동, 우유와 커피섭취, 수면 등이었다. 여자에서는 TC, TG, LDL, 수축기와 확장기혈압, 비체중 그리고 커피섭취와 수면 등이었다. 남자에서 총콜레스테롤의 평균은 181.7mg/dl(표준편차, 32.2), 여자는 182.5mg/이(표준편차, 42.2)였다. 대부분의 위험인자들은 구미의 수준에 미치지 못했으나 남자에서 흡연율이 전체적으로 61.8%로 높으 수준이었으며 특히, 20~29세가 72.9%, 30~39세가 75.2%로서 다른 연령군에 비해 상대적으로 높았다. 여자에서는 전체적으로 6.0%에 지나지 않았다. 확장기혈압 90mmHg 이상을 고혈압자로 정의했을 때의 유병률이 여자 전체대상자에서 24.7%로 높았으며 50-59세는 표본수가 적어서 문제가 되었으나 53.1%였다. 어떤 인구집단내에서 총콜레스테롤의 평균이 200mg/dl 미만이면 고혈압과 흡연의 인구집단의 수준에 관계없이 관상동맥질환(coronary heart disease)의 발생은 드문 것으로 보고가 되고 있으므로 당분간 관상동맥질환 발생률의 급속한 절대적인 증가는 힘드리라 사료된다. 그러나 이러한 결과는 본 연구의 대상자들이 대표성을 지니지 못하며 건강검진센터에 자발적으로 내원한 사람들이므로 해석에 주의를 요한다. Authors examined the distributions of the risk factors for the coronary heart disease in the 422 male (69.9%) and 182 female (30.1%) visitors to the health examination center of a university hospital located in Taegu March to August 1991. Mean age of males was 43.3(standard deviation, SD 10.3) and that of females was 44.4(SD 10.8). Total cholesterol(TC), triglyceride (TG), high-density lipoprotein and low-density lipoprotein cholesterol(LDL), systolic blood pressure, Quetelet index, and Type A Behavior Pattern, and some of life habit variables(alcohol intake, smoking, regular exercise, milk and coffee intake and sleeping) were statistically significant in age groups of the males(P<0.05). In the females, TC, TG and LDL, systolic and diastolic pressure, Quetelet index, coffee intake and sleeping were statistically significant in age groups (P<0.05). Mean of total cholesterol was 181.7㎎/dl(SD,32.2) in males and that of females was 182.5㎎/dl(SD,42.2). Most of the risk factors levels were lower than the Euro-Americans', while smokers were high with 61.8%, especially 72.9% in 20-29 age group and 75.2% in 30-39 age group in males. In females, smokers were just 6.0%. Hypertensives defined by more than 90mmHg diastolic pressure were 24.7% in females, particularly 53.1% in 50-59 age group, but size of the strata was rather small(N=49). In the light of the report that coronary heart disease is uncommon irrespective of population levels of smoking and hypertension, where average total blood cholesterol level in a population is low(<200mg/dl), it is not likely that the absolute increase of the number of the coronary heart disease will increase markedly in the near future. But cautions should be exercised in interpreting the results of this study due to the lack of representativeness and volunteerism. .

      • KCI등재

        통신상품간 시장잠식현상과 경쟁도입의 효과분석

        이상호,정충영,이현우 한국경영과학회 1996 한국경영과학회지 Vol.21 No.1

        We consider a consumer self-selection model in which a regulated firm faces two market segmants wig differing valuation of quality of telecommunication services and examine some economic implications from the behaviors of the firm. In the context of a regulated monopolist, even though the results depend on the degree of privatization, the firm could lower the quality of the low-end model and reduce the price of the high-end in order to alleviate cannibalization. This justifies the provision of universal service policy in the telecommunications market. Based on this self-selection model, we also analyze an extended model of product introduction and show that the monopolist will introduce new product with the same introduction time of social planner. However, when we consider competition among firms, the market equilibrium may not guarantee the efficient time of product introduction.

      • 한국 여성교육의 전개과정에 있어서 기독교의 역할과 과제

        이현섭,박충일 진주산업대학교 1993 論文集 Vol.32 No.-

        The purpose of this study is to investigate ⑴ the role of the Christianity in Korean women's education, ⑵ the evaluation of Korea women's education based on Christianity, ⑶ the tasks that Christianity must perform for the future Korean women's education. The result of this study as follows: First, the role of Christianity is developmental process of Korea women's education has been differently performed in times. Specifically, the role of Christianity in enlightenment period was release from traditional customs, the role of Christianity in Japanese Imperialism period was enlargemant of patriotism and independent consciousness, the role of Christianity in after 8·15 liberation was establishment of democratic consciousness. Second, the evaluation of Christianity for Korean women's education suggested to positive and negative role. Finally, the most important tasks for future women's education would have new understanidng on the mission of Christianity and recognition of the historical and social need.

      • 일차배양된 설치류 호흡기 상피세포로부터의 점액소 분비에 대한 수종 약물의 영향

        이충재,석정호,이재흔,허강민,박지선,배소현,노삼길,박상철 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

        1. PKC activator인 PMA는 일차배양 HTSE세포로부터의 뮤신분비를 0.1μM 농도에서 30%, 1μM 농도에서 80% 가량 증가시켰다. 2. 식물 유래 성분으로, flavonoid의 일종인 TFR은 일치배양 HTSE 세포로부터의 뮤신분비를 10μM 농도에서 50%, 100μM 농도에서 80% 가량 증가시켰다. 3. 양이온성 폴리펩티드인 PLL 및 PLA는 일차 배양 HTSE 세포로부터의 뮤신분비를 0.01 - 10μM 농도에서 용량의존적으로 감소시켰다. 4. 결론적으로, 본 연구에서 얻어진 결과들은 새로운 거담제 및 점액용해제나 단백분해 효소제가 아닌 호흡기 류신의 생성/분비를 조절해 줄 수 있는 신개념의 약물을 개발함에 있어 극히 일부분이나마 단서를 제공하고 있다고 하루 수 있을 것이다. In the present study, we tried to investigate whether phorbol myristate acetate(PMA), trihydroxymethoxy-flavanone rutinoside(TFR) and cationic polypeptides significantly affect mucin release(secretion) from cultured hamster tracheal surface epithelial cells. Confluent primary hamster tracheal surface epithelial (HTSE) cells were metabolically radiolabeled with 3H-glucosamine for 24 hr and chased for 30 min in the presence of each agent to assess the effect on 3H-mucin release. The results were as follows : (1) Both PMA and TFR significantly increased mucin release from cultured HTSE cells ; (2) Cationic polypeptides including po1y-L-lysine(PLL, mw 7,500) and poly-L-arginine(PLA, mw 10,800) significantly inhibited mucin release from cultured HTSE cells, in a dose-dependent manner. This finding suggests us that PMA and TFR be further studied for the possible use as mild expectorants and cationic polypeptides might function as a regulator for hyper-secretion of mucus, both by direct acting on airway mucin-secreting cells, during the treatment of chronic airway diseases.

      • 지베렐린 관련 유전자 증폭을 위한 최적 PCR 반응 조건

        이용현,김충일,이미영 순천향대학교 기초과학연구소 2001 순천향자연과학연구 논문집 Vol.7 No.1

        Optimum conditions of PCR amplification for gibberellin-related genes such as GOX2 and GAI were determined by altering annealing temperature and primer concentration in order to minimize mispriming PCR products. Selective amplifications of GOX2 and GAI genes were performed with 40 ng template DNA, 0.5 μM M13 forward/reverse primer and annealing temperature of 62 ℃. 30 cycles of PCR reaction profiles were denaturation for 60 sec at 94 ℃, annealing of primers for 60 sec at 62 ℃, extension of primers for 60 sec for 72 ℃, final extension for 5 min at 72 ℃ and cooling at 4 ℃.

      • SCOPUSKCI등재

        소아 수부 화상의 임상적 고찰

        이두형,류인성,장충현 大韓成形外科學會 1993 Archives of Plastic Surgery Vol.20 No.3

        During 10 years from June 1982 to June 1992, 266 patients were visited to the Department of Plastic and Reconstructive Surgery in Kyung Hee University Hospital, for treatment of pediatric hand burn. The most common etiology of pediatric hand burns was scalding burn(41.7%), followed by flame(25.2%), steam(18.8%), contact(10.5%), and electrical burn(3.8%) but, at recent after 1984, the most common etiology was changed to steam burn(51.1%), followed by scalding(21.5%), flame(10.2%) contact burn (10.2%)and electrical burn(6.8%). The age distribution of the patients was as follows ; early infantile period(8.3%), late infantile period(19.9%), toddler period(39.8%), preschool age(23.7%), and school age(8.3%) but all of steam burn was developed before 3 years old, especially, in late infantile period(7 month~1 year). Males were affected more often than females. Male to female ratio was 1.2 : 1, especially in steam burn and electrical burn, male more predominated. The most frequent affected region was middle finger(61.7%), followed by index finger(54.5%), little finger(44.0%), thumb(30.5%), palm(30.0%), dorsum of hand(7.3%) and wrist(17.3%). The most frequently affected web space in postburn syndactyly was second web space, followed by third(30.9%), fourth(24.1%) and first(13.6%), especially in steam burn, the most frequently affected web space was second web space(52.8%), The highest incidence of pediatric hand burn was in winter(45.2%), followed by spring(25.0%), autumn(16.9%) and summer(12.9%) but, steam burn was developed all around monthly. The most common type of surgical procedure was release and FTSG(59.2%), followed by release and STSG(21.9%), Z-plasty(16.8%), distant flap(1.5%), and free flap(0.6%).

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