Postoperative quality of life after gastrectomy in gastric cancer patients: a prospective longitudinal observation study

Chao-Jie Wang,Yun-Suhk Suh,Hyuk-Joon Lee,Ji-Hyeon Park,Shin-Hoo Park,Jong-Ho Choi,Fadhel Alzahrani,Khalid Alzahrani,Seong-Ho Kong,Do-Joong Park,Hui Cao,Han-Kwang Yang 대한외과학회 2022 Annals of Surgical Treatment and Research(ASRT) Vol.103 No.1

Purpose: The European Organization for Research and Treatment of Cancer quality of life (QOL) questionnaires (QLQ-C30, QLQ-OG25, and QLQ-STO22) are widely used for the assessment of gastric cancer patients. This study aimed to use these questionnaires to evaluate QOL in postgastrectomy patients. Methods: We prospectively evaluated 106 patients with distal gastrectomy (DG), 57 with pylorus-preserving gastrectomy (PPG), and 117 with total gastrectomy (TG). Body weight and QOL questionnaires were evaluated preoperatively and postoperatively (at 3 weeks, and 3, 6, and 12 months). Results: TG patients had significantly more weight loss than DG/PPG patients. Compared with DG, patients after PPG had less dyspnea (P = 0.008) and trouble with coughing (P = 0.049), but more severe symptoms of insomnia (P = 0.037) and reflux (P = 0.030) at postoperative 12 months. Compared with DG/PPG, TG was associated with worse body image, dysphagia, eating, and taste in both OG25 and STO22. Moreover, OG25 revealed worse QOL in the TG group with respect to odynophagia, eating with others, choked when swallowing, trouble talking, and weight loss. The QOL of patients who received chemotherapy was worse than those in the chemo-free group in both physical functioning and symptoms such as nausea/vomiting, appetite loss, and trouble with taste; however, these side effects would soon disappear after finishing chemotherapy. Conclusion: PPG was similar to DG in terms of postoperative QOL and maintaining body weight, while TG was always inferior to both DG and PPG. Adjuvant chemotherapy can affect both body weight and QOL despite being reversible.

A band selection method for hyperspectral image classification based on improved Particle Swarm Optimization

Jie Shen,Chao Wang,Ruili Wang,Fengchen Huang,Chao Fan,Lizhong Xu 보안공학연구지원센터 2015 International Journal of Signal Processing, Image Vol.8 No.4

With the development of spectral imaging technology, it makes hyperspectral imagery widely used. According to the features of multiple bands and the strong mutual correlation among these bands, this paper presents a band selection method for hyperspectral imagery classification based on improved PSO (Particle Swarm Optimization). First of all, we use information divergence to describe the correlation of the bands, then build the information divergence matrix to make the classification of subspaces. Secondly, we construct the fitness function of the algorithm with the band information and categories of the Bhattacharyya distance (B distance) to improve the inertia weight updating method in PSO. Finally, based on the AVIRIS hyperspectral imagery and compared with existing method to conduct experiments, the average classification accuracy of the proposed method is 81.36%, which is distinctly improved 0.91% compared with the existed method. Meanwhile, the proposed method has a significantly faster convergence speed during the process of the band selection. Therefore, the experimental results verify the effectiveness of the proposed method in this paper.

Simulation Experiment on Acoustic Emission of Pipeline Leakage

Wang Xin-hua,Yang Jie,Jiao Yu-lin,Niu Yong-chao 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.2

With the heater pipeline leakage experiment conducted on the experiment table, inner pipeline leakage of heater was studied through the leakage failure detection system. The frequency distribution and the amplitude of acoustic emission signals of leakage versus internal pressure were analyzed. Variations of signals versus leakage aperture and dissemination distance were summarized. According to the mapping relationship between the leaking spot and acoustic emission signals, and between the leakage flow and acoustic emission signals, reasons of leakage failure were concluded. The results would be applied to heater leakage failure detection. And an on-the-spot detection in the power plant was conducted to test the heater under pressure in order to verify the results.

Influence of heat treatment on the wear life of hydraulic fracturing tools

Chao Zheng,Yonghong Liu,Hanxiang Wang,Jie Qin,Yang Shen,Shihong Zhang 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.2

Wear phenomenon has caused severe damage or failure of fracturing tools in oil and gas industry. In this paper, influence of heat treatment on the mechanical properties and wear resistance of fracturing tool made of lamellar graphite grey cast iron were investigated. The surface composition and microstructure were characterized by X-ray diffraction (XRD) and metallographic microscope. Sliding wear tests were performed to study the tribological behavior. Tests results showed that wear rates of treated specimens decreased by 33 %. Besides, worn morphology and wear debris were analyzed using Scanning electron microscope (SEM) and Energy dispersive Xray spectra (EDS). Wear failure mechanisms of specimens were identified. Furthermore, on-site experiment results indicated that wear loss of treated samples decreased by 37.5 %. The wear life of hydraulic fracturing tools can be improved obviously by the heat treatment.

Nonlinear Model Predictive Control for Near-Space Interceptor Based on Finite Time Disturbance Observer

Chao Guo,Chen Song,Yu-Jie Zhao,Jun-Wei Wang 한국항공우주학회 2018 International Journal of Aeronautical and Space Sc Vol.19 No.4

This paper proposes a novel nonlinear model predictive control design method based on the finite time disturbance observer (FTDO) and dynamic control allocation (DCA) algorithm for the near-space interceptor (NSI). First, the FTDO is introduced to estimate the mismatched system disturbance. The nonlinear model predictive control scheme based on the estimation value is proposed to obtain the virtual control command, and the mismatched disturbance can be effectively removed from the output channels of the NSI by designing a feed-forward disturbance compensation term with an appropriate compensation gain matrix. Moreover, a new DCA method is given to distribute the above virtual control command among the corresponding actuators (reaction jets and aerodynamic fins). Finally, numerical simulations illustrate that the proposed control scheme can track the command signal with high precision and have strong robustness against the mismatched disturbance.

Online Leakage Detection Test of High-pressure Heater at the Power Plant

Wang Xin-hua,Jiao Yu-lin,Niu Yong-chao,Yang Jie 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.3

Variations of acoustic emission signals of leakage of the heater versus inner pressure, leakage aperture, transmission distance and liquid state in the outer pipeline were studied through experiment and analysis. By changing one of the four factors each time, leakage failure reasons were concluded. Research results would be applied into leakage detection of heater.

One New Pregnane Glycoside from the Seeds of Cultivated Brucea javanica

Jie-Qing Liu,Ming-Hua Qiu,Cui-Fang Wang,Xing-Yao Li,Jian-Chao Chen,Yan Li 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.8

A new pregnane glycoside, named (20R)-O-(3)-β-D-glucopyranosyl-(1→2)-α-L-arabinopyranosyl-pregn-5-en-3β,20-diol (1), and seven known compounds, brusatol (2), bruceine B (3), bruceine D (4), yadanziolide A (5), bruceine E (6), yadanzioside G (7), and yadanzioside B (8), were isolated from the cultivated dry seeds of Brucea javanica. The structure of 1 was elucidated on the basis of 1D- and 2D-NMR spectroscopic analyses. Their inhibitory effects on tumor cells were also tested. Compound 1 was slightly active against HL-60, SMMC-7721, A-549, and MCF-7 tumor cells. Compounds 2 and 3 demonstrated significant inhibitory activities against all tested cells. These results indicate that cultivated B. javanica could replace the wild plant as an antitumor plant resource.

Clinico-Pathological Significance of MHC-I Type Chain-associated Protein A Expression in Oral Squamous Cell Carcinoma

Wang, Jie,Li, Chao,Yang, Dan,Jian, Xin-Chun,Jiang, Can-Hua Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.2

The current research concerns the clinicopathological significance of MHC class I chain-related protein A (MICA) expression in oral squamous cell carcinomas (OSCCs). The expression and location of MICA protein in 14 normal oral mucous and 45 cancerous and para-cancerous tissues were assessed by immunohistochemistry and levels of MICA mRNA expression in 29 cancerous and para-cancerous tissues were determined by the real-time polymerase chain reaction. Data were analyzed with the SPSS16.0 software package. MICA was found to be located in the cytoplasm and plasma membrane. Expression was higher in para-cancerous than in cancerous tissues (P < 0.05). However, no statistical difference was found between the following: 1) para-cancerous tissue with normal mucosa; 2) normal mucosa with cancerous tissue;and 3) among different clinicopathological parameters in OSCC (P > 0.05). The level of MICA mRNA was higher in OSCCs than in para-cancerous tissues, and was correlated with the regional lymph node status and disease stage (P < 0.05). The levels of MICA protein and mRNA expression differ among normal oral mucosa, para-cancerous tissue, and cancerous tissue. MICA may contribute to the tumorigenesis and progression of OSCC.

Molecular characterization and expression pattern of Rubisco activase gene GhRCAβ2 in upland cotton (Gossypium hirsutum L.)

Chao Maoni,Huang Ling,Dong Jie,Chen Yu,Hu Genhai,Zhang Qiufang,Zhang Jinbao,Wang Qinglian 한국유전학회 2024 Genes & Genomics Vol.46 No.4

Background Rubisco activase (RCA) is a pivotal enzyme that can catalyse the activation of Rubisco in carbon assimilation pathway. Many studies have shown that RCA may be a potential target for genetic manipulation aimed at enhancing photosynthetic efficiency and crop yield. Objective To understand the biological function of the GhRCAβ2 gene in upland cotton, we cloned the coding sequence (CDS) of the GhRCAβ2 gene and investigated its sequence features, evolutionary relationship, subcellular localization, promoter sequence and expression pattern. Methods The bioinformatics tools were used to analyze the sequence features of GhRCAβ2 protein. Transient transformation of Arabidopsis mesophyll protoplasts was performed to determine the subcellular localization of the GhRCAβ2 protein. The expression pattern of the GhRCAβ2 gene was examined by analyzing transcriptome data and using the quantitative real-time PCR (qRT-PCR). Results The full-length CDS of GhRCAβ2 was 1317 bp, and it encoded a protein with a chloroplast transit peptide. The GhRCAβ2 had two conserved ATP-binding domains, and did not have the C-terminal extension (CTE) domain that was unique to the RCA α-isoform in plants. Evolutionarily, GhRCAβ2 was clustered in Group A, and had a close evolutionary relationship with the soybean RCA. Western blot analysis demonstrated that GhRCAβ2 was immunoreactive to the RCA antibody displaying a molecular weight similar to that of the RCA β-isoform. The GhRCAβ2 protein was found in chloroplast, aligning with its role as a vital enzyme in the process of photosynthesis. The GhRCAβ2 gene had a leaf tissue-specific expression pattern, and the yellow-green leaf mutant exhibited a decreased expression of GhRCAβ2 in comparison to the wild-type cotton plants. The GhRCAβ2 promoter contained several cis-acting elements that respond to light, phytohormones and stress, suggesting that the expression of GhRCAβ2 may be regulated by these factors. An additional examination of stress response indicated that GhRCAβ2 expression was influenced by cold, heat, salt, and drought stress. Notably, diverse expression pattern was observed across different stress conditions. Additionally, low phosphorus and low potassium stress may result in a notable reduction in the expression of GhRCAβ2 gene. Conclusion Our findings will establish a basis for further understanding the function of the GhRCAβ2 gene, as well as providing valuable genetic knowledge to improve cotton photosynthetic efficiency and yield under challenging environmental circumstances. Background Rubisco activase (RCA) is a pivotal enzyme that can catalyse the activation of Rubisco in carbon assimilation pathway. Many studies have shown that RCA may be a potential target for genetic manipulation aimed at enhancing photosynthetic efficiency and crop yield. Objective To understand the biological function of the GhRCAβ2 gene in upland cotton, we cloned the coding sequence (CDS) of the GhRCAβ2 gene and investigated its sequence features, evolutionary relationship, subcellular localization, promoter sequence and expression pattern. Methods The bioinformatics tools were used to analyze the sequence features of GhRCAβ2 protein. Transient transformation of Arabidopsis mesophyll protoplasts was performed to determine the subcellular localization of the GhRCAβ2 protein. The expression pattern of the GhRCAβ2 gene was examined by analyzing transcriptome data and using the quantitative real-time PCR (qRT-PCR). Results The full-length CDS of GhRCAβ2 was 1317 bp, and it encoded a protein with a chloroplast transit peptide. The GhRCAβ2 had two conserved ATP-binding domains, and did not have the C-terminal extension (CTE) domain that was unique to the RCA α-isoform in plants. Evolutionarily, GhRCAβ2 was clustered in Group A, and had a close evolutionary relationship with the soybean RCA. Western blot analysis demonstrated that GhRCAβ2 was immunoreactive to the RCA antibody displaying a molecular weight similar to that of the RCA β-isoform. The GhRCAβ2 protein was found in chloroplast, aligning with its role as a vital enzyme in the process of photosynthesis. The GhRCAβ2 gene had a leaf tissue-specific expression pattern, and the yellow-green leaf mutant exhibited a decreased expression of GhRCAβ2 in comparison to the wild-type cotton plants. The GhRCAβ2 promoter contained several cis-acting elements that respond to light, phytohormones and stress, suggesting that the expression of GhRCAβ2 may be regulated by these factors. An additional examination of stress response indicated that GhRCAβ2 expression was influenced by cold, heat, salt, and drought stress. Notably, diverse expression pattern was observed across different stress conditions. Additionally, low phosphorus and low potassium stress may result in a notable reduction in the expression of GhRCAβ2 gene. Conclusion Our findings will establish a basis for further understanding the function of the GhRCAβ2 gene, as well as providing valuable genetic knowledge to improve cotton photosynthetic efficiency and yield under challenging environmental circumstances.

Novel NiCo2Se4/Mn0.5Cd0.5S photocatalyst for visible light-driven hydrogen evolution

Liu Chao,Zhang Feng-Jun,Wang Ying-Rui,Xie Wen-Jie,Ma Jie,Oh Won-Chun 한국세라믹학회 2023 한국세라믹학회지 Vol.60 No.4

The development of efficient and stable photocatalysts is one of the most important research directions to realize the practical application of photocatalytic hydrogen evolution. A series of novel visible light responsive NiCo 2Se4/Mn0.5Cd0.5S composites with different NiCo 2Se4 contents were prepared by hydrothermal method. The composites were characterized using different characterization techniques such as XRD, SEM, TEM, XPS, UV–Vis DRS, PL, and photoelectrochemistry. Photocatalytic hydrogen evolution reaction was also performed using visible light (λ > 420 nm) in an aqueous solution containing Na 2S·9H2O and Na 2SO3 as sacrificial reagents. The 4% NiCo 2Se4/ Mn 0.5Cd0.5S composites exhibited the highest photocatalytic hydrogen evolution capacity, producing 20 mmol  h −1  g−1 of hydrogen, higher than pure Mn0.5Cd0.50.5S (12.2mmol h-1g-1). The tight bonding of the two materials in the NiCo 2Se4/Mn0.5Cd0.5S composites may enhance the photocatalytic activity to some extent. The possible mechanism was suggested by UV–Vis DRS and photoelectrochemical measurements. The obtained NiCo 2Se4/ Mn0.5Cd0.5S composites have excellent photocatalytic activity and good stability in photocatalytic hydrogen evolution, and have potential applications in the photocatalytic hydrogen evolution from water using solar energy.