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      • KCI등재

        Changes in Spatiotemporal Parameters and Lower Limb Coordination During Prosthetic Gait Training in Unilateral Transfemoral Amputees

        Yunhee Chang,Chang-Yong Ko,Bo Ra Jeong,Jung Sun Kang,Hyuk-Jae Choi,Gyoosuk Kim,Hyunjun Shin,Sehoon Park 한국정밀공학회 2022 International Journal of Precision Engineering and Vol.23 No.3

        When applying prosthetic gait training to patients with lower limb amputation, monitoring the gait change process is crucial for establishing and modifying rehabilitation training plans. In addition, since human gait involves complex movement of several joints, it is necessary to analyze the organic movement of adjacent joints rather than a single joint in the lower extremities for understanding the process of gait change. Therefore, this study aimed to analyze changes in spatiotemporal parameters and lower limb coordination during prosthetic gait training in unilateral transfemoral amputees (TFAs). This retrospective case–control study included 10 unilateral TFAs and 10 healthy individuals as controls. TFAs received prosthetic gait training for 12 weeks and gait changes were analyzed every 2 weeks using a 3D motion analysis system. The measured variables were spatiotemporal parameters and the continuous relative phase between hip and knee joints. The highest improvement in walking speed was seen at week 4 of training, and the continuous relative phase was most symmetric at week 8. The lower limb coordination pattern was more in-phase in the TFAs than in the controls, and the coordination variability was also lower for the TFAs than for the controls. In addition, the rate of change in lower limb coordination of TFAs was lower than that of spatiotemporal parameters and was significantly different from that of the controls even after training. Considering that the decrease in lower limb coordination is related to gait efficiency, balance, and risk of fall, there is a need to develop therapeutic strategies that can further improve the coordination of TFAs.

      • KCI등재

        측두하악관절 골관절염 환자의 진단에서 Cone Beam 전산화 단층촬영의 유용성

        노창세,정연화,태일호,고명연,안용우,Roh, Chang-Se,Jung, Yun-Hoa,Tae, Il-Ho,Ko, Myung-Yun,Ahn, Yong-Woo 대한안면통증구강내과학회 2009 Journal of Oral Medicine and Pain Vol.34 No.1

        This study is designed to assess Relationship between clinical diagnosis of Temporomandibular Joint Disorder and diagnostic finding of Cone Beam Computed Tomography(CBCT) The author performed clinical examination for TMD Patients who visited Orofacial pain clinic, Jin-ju ooo Dental office. CBCT(Cone beam computed tomography) was taken for 190 joints in 95 subjects. A Oral medicine and Oral radiologist evaluated CBCT each other. then we compared with that result, Condyle bony changes were classified by no bone change, flattening, erosion and osteophyte. The obtained results were as follow: 1. The Kappa index of the diagnosis between oral medicine and oral radiogist were high, the index of diagnosis by degenerative joint disease were more higher. 2. The Kappa index of panoramic view and CBCT was low, more condylar bone chages were observed by CBCT diagnosis 3. Condylar bone changes of the 54.2% of non-DJD group clinicaly was observed by CBCT diagnosis and no bone changes of the 15.3% of DJD group.was observed by CBCT 4. TMJ pain was associated with erosion of condyle bone change of TMJ. Crepitation and longest duration of TMD were associated with osteophytic bone change.

      • KCI등재

        Swivel joint를 이용한 비대칭 발치증례의 교정적 공간폐쇄

        고창희,임성훈,김광원,정동기,김도영,박선주,양용근 조선대학교 구강생물학연구소 2003 口腔生物學硏究 Vol.27 No.1

        Extraction therapy is popular treatment protocol in orthodontics. Generally, symmetric premolar extraction is performed. But, in some cases, asymmetric extraction is required to solve asymmetric dental alignment. But asymmetric extraction treatment has side effects and disadvantages like a) collapse of dental arch form. b) canting of occlusal plane, c) extended treatment duration. For a good treatment result, we applied the orthodontic space closing arch wire with swivel joint to allow rotational movement of arch wire segments during space closure, Now we present a case treated with orthodontic space closing arch wire with swivel joint.

      • 과채류 잔류성 농약의 돌연변이 유발성

        고용구,김성홍,오창경,오명철,김수현 濟州大學校 産業技術硏究所 1995 산업기술연구소논문집 Vol.6 No.-

        Twelve residual pesticides which applied on the fruits and vegetables cultivation were tested for mutagenic activity using Salmonella typhimurium TA strain. Mutagenic activities against Tedion, Monopho, Danoton, Ometon and Captan of twelve pesticides tested were strong, Thalonil, Prosing, EPN, Phentoate, Dicopol and Captan were medium, and Dicopol were no. Tedion, hlonopho and Danoton showed strong mutagenic activities on TA98, Thalonil, Prosing, EPN, Phentoate, Parathion and Sappiran showed medium, and Danoton showed weak, while Dicopol and Sappiran showed no. At the other hand, Tedion, Danoton, Ometon and Captan showed storng mutagenic acitivities on TA100, Thalonil and Monopho showed medium and Prosing, Phentoate, Parathion and Sappiran showed weak, while EPN and Dicopol showed no. Therefore, EPN identified mutagen which induced only frameshift mutation, Sappiran was only base-substitution, and nine except these and Dicopol of twelve pesticides tested were mutagens which induced both frameshift and base-substitution mutation.

      • 사람 HPRT 유전자 발현벡터 제조와 생쥐 Sp2/0 myeloma 세포주에서의 발현

        고창보,김용만,김영진,백상기 충남대학교 기초과학연구소 1997 忠南科學硏究誌 Vol.24 No.1

        To construct expression vector for the human HPRT gene, pRSVneo plasmid conferring resistance to neomycin-kanamycin(Tn5) antibiotics and pHPT 31 containing human HPRT cDNA were used to subclone human HPRT cDNA. For construction of recombinant pRSVneo carrying human HPRT, pRSVneo-HPRT, the human HPRT cDNA fragment from pHPT31 plasmid was inserted into polyadenylation site (BamHI site) behind the neo gene fragment of pRSVneo plasmid. For the other expression vector, pRSV-HPRT, the neo gene and small portion of the untranslated 5′franking region were removed from the pRSVneo-HPRT. The HPRT gene of the two vectors were constructed in right orientation. Each recombinant vector was introduced into cultured HPRT-deficient mouse cell line, Sp2/0 by calcium mediated DNA transfection and the transfected cells were selected under HAT selection condition. The HPRT activity of the lysates from the selected cell was higher than that of the lysates from spleen cells of mouse. The HPRT activity of pRSVneo-HPRT vector was higher than that of pRSV-HPRT one. To find out whether the HPRT activity of the transfected cells selected under HAT medium was expressed by transfected vectors or by spontaneous mutations, it was cultured to reselect in G418 medium. It showed that the nature of the HPRT activity was resulted from the transfected vectors.

      • 수중 가청음에 의한 쏨벵이의 청각능력 : 2. 청각 임계비

        이창헌,박용석,문종욱,강창익,김고환,서두옥 제주대학교 해양연구소 1999 해양자원연구소연구보고 Vol.23 No.-

        수중 가청음은 어군의 행동 제어와 해양목장화에서 음향 순치에 많이 이용되고 있다. 수중 가청음에 의한 어류반응 해석을 하기 위해서는 물고기의 청각능력을 정확히 파악할 필요가 있으며,오래전부터 여러물고기의 청각능력을 관련된 연구가 수행되었다.

      • Lactobacillus casei YIT 9018로부터 분리·정제한 Cell Wall Skeleton의 In Vitro 항종양 활성

        金昌漢,李明燮,高時煥,朴相瑨,高明秀,白永振 건국대학교 1995 學術誌 Vol.39 No.2

        In vitro antitumor activity of cell wall skeleton(CWS) purified from Lactobacillus casei YIT 9018 was examined by clonogenic assay. CWS had antitumor activity against six human tumor cell lines and three mouse tumor cell lines. Antitumor activity of CWS against human tumor cell lines such as A-427, SKMES-1, SF-188, FARROW, RAJI and HEP-2 was observed at 300,800,400,700,900 and 1,000μg/ml concentration, respectively. Antitumor activity of CWS against mouse tumor cell lines such as 3LL, S-180 and P388 was observed at 50,500 and 900μg/ml concentration, respectively. Key words : Lactobacillus casei YIT 9018, Cell Wall Skeleton, Antitumor Activity, Clonogenic Assay

      • KCI등재

        알콜精神病患者에 對한 臨床的 硏究 : 幻覺內容을 中心으로

        尹昌範,高診富,嚴龍燮 大韓神經精神醫學會 1976 신경정신의학 Vol.15 No.2

        The author studied mainly the hallucinated phenomena of the 15 alcoholic psychotics who were hospitalized in Dept. of Neuro-Psychiatry, of Medical college, Chosun University, from October of 1972 to October of 1975. The following conclusions were obtained from the studies. 1) In general distribution of age, the average of the alcoholic psychotics was 40.5 years, with a range from 35 to 43 years. The range of age is significant, the alcoholic psychotics being a much more homogenous group. The rate of males to females among the alcoholic psychotics was 15 to 0. 2) This report will concern data from a group of 9 patients (60%) who were diagnosed as Delirium tremens and from 4 patients who were diagnosed as having Alcoholic Hallucinosis (25%) without schizophrenia and from 2 Patients (13%) of Korsakoff's psychosis who is less than others. 3) Alcoholic psychosis is the special disease of men in Korean society but not less and it is the most part in the lower class of the educational, socio-cultural level and the lower income class. 4) Their average of drinking capacity of a day is the 2 bottles (which is filled with 2 HOB) of SOJU (spirits) and 2-3 DOI of MAKOULLI, howerever they used not to get some eatables. 5) I found the light tremulousness (80%), insomnia (93%), night-mare or vivid dreams (53%), itching (47%), retching (33%), sweating (13%), seizure (27%) and blurred vision (20%) to be part of the alcoholic withdrawal syndrome. 6) The most frequent incidence was in the formed visual hallucinations (80%), followed by the formed auditory hallucinations (60%) and haptic hallucinations (58%). 7) In the contents of visual hallucinations, the bug, flea and snake are the most part but few seen the case of a rat. The contents of visual hallucinations in western people is the snake and rat which is the most part, such a difference between western and oriental people should be taken into account of the comparative cultural aspects. 8) Alcholic psychotics gave more responses regards as persecutory and every day affairs. 9) Alcoholic psychotics perceived the phenomena externally to any extent. 10) Alcoholic psychotics frequently thought that the hallucination was real at the time of it's appearance but later in the recovery period expressed recgnition of it's unreality and alcoholic psychotics behaved negatively or ambivalently in majority of cases.

      • 동 모더나이트 촉매상에서 NOx의 제거 반응

        모용기,이창용,최고열 서울産業大學校 2001 논문집 Vol.52 No.1

        구리를 담지시킨 모더나이트를 이용하여 고정층 연속흐름 반응기에서 NO의 환원 및 분해 반응을 실시하였다 전처리로 산화된 CuO/HM의 NO 직접 분해 반응은 구리의 담지량 및 반응 온도의 증가에 따라 전화율이 증가하였다. CuO/HM 촉매상에서 CO를 이용한 NO의 환원 반응에서의 전화율은 공급되는 반응물의 양론비에 따라 달라졌다. NO/CO의 비가 1일때 NO는 거의 100% 가까운 전화율을 나타내었으며, 이 비가 증가할수록 전화율은 감소하였다. CuO/HM 촉매상에서 CO를 이용한 NO 환원 반응과 직접 분해 반응의 결과는 CuO/HM 촉매상에서의 결과와 유사한 경향을 나타내었다. The catalytic reduction and decomposition of NO has been carried out on copper impregnated mordenites in a packed bed flow reactor. The conversion of NO by direct decomposition on CuO/HM increased with the amount of copper loaded and the reaction temperature. In the reduction of NO with CO on CuO/HM, the conversion of NO was influenced by the ratio of NO to CO supplied as reactants The conversion of NO was almost 100% when the ratio of NO to CO was one. However, it decreased with the increase of the reactant mole ratio. The results of direct decomposition of NO as well as the reduction of NO with CO on Cu0/HM showed the same trends as those on CuO/HM

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