실내 기후동에서 개인형 국소냉방 장치의 기류 및 온도 분포해석

엄태인,장은숙,경남호,신기식,문승현,전영남,류창국 한밭대학교 생산기반기술연구소 2002 생산기반기술연구소 논문집 Vol.2 No.1

Numerical simulation is performed by the commercial code FLUENT for individual air condition system to calculate the velocity and temperature profiles around worker in climate room. The main calculation region is the space of ㄱ shape between wall and worker in the individual air condition system. The fresh air is emitted from 3 inlet attached on the right, left and center wall. Because the comfort of worker is closely related with the velocity and temperature of wind, these data are key role for design of the individual air condition system. This work is previous study for evaluation of thermal comfort of workers in room without much experiments according to metabolism and heat emission of human body. Numerical simulation results are as followings, 1. There is an possibility of the thermal comfort of worker is gotten worse due to the presence of dramatic change of wind velocity around worker. 2. Temperature gap exists in worker's body between top and bottom according to fresh air inlet velocity and position which is right, left and center of wall. 3. Calculation results of the skin temperature of worker are key data for evaluation of thermal comfort with experimental data in climate room. 4. Optimum condition of temperature, direction and velocity of fresh air will be obtain by numerical simulation for energy effective individual air condition system.

Eagle’s syndrome: a case report

Chang-Sig Moon,Baek-Soo Lee,Yong-Dae Kwon,Byung-Jun Choi,Jung-Woo Lee,Hyun-Woo Lee,Sun-Ung Yun,Joo-Young Ohe 대한구강악안면외과학회 2014 대한구강악안면외과학회지 Vol.40 No.1

Eagle’s syndrome is a disease caused by an elongated styloid process or calcified stylohyoid ligament. Eagle defined the disorder in 1937 by describing clinical findings related to an elongated styloid process, which is one of the numerous causes of pain in the craniofacial and cervical region. The prevalence of individuals with this anatomic abnormality in the adult population is estimated to be 4% with 0.16% of these individuals reported to be symptomatic. Eagle’s syndrome is usually characterized by neck, throat, or ear pain; pharyngeal foreign body sensation; dysphagia; pain upon head movement; and headache. The diagnosis of Eagle’s syndrome must be made in association with data from the clinical history, physical examination, and imaging studies. Patients with increased symptom severity require surgical excision of the styloid process, which can be performed through an intraoral or an extraoral approach. Here, we report a rare case of stylohyoid ligament bilaterally elongated to more than 60 mm in a 51-year-old female. We did a surgery by extraoral approach and patient’s symptom was improved.

白鼠急性 虛血性 腎臟의 技能的 및 形態學的 變化에 미치는 Dimethyl Sulfoxide의 影響

이동근,장양욱,문우성,김달식,최호열 의과학연구소 1991 全北醫大論文集 Vol.15 No.1

This experimental study was carried out to investigate the effect of dimethyl sulfoxide on the functional and morphological changes of actue ischemic renal failure. Following unilateral nephrectomy, acute ischemic renal failure was induced by clamping of renal artery of the remaining kidney and reperfused afrer one hour. Immediately after reperfusion, experimental group received 5ml of 20% solution of dimethyl sulfoxide intrave- nously at a constant rate(0.5ml/min.) using infusion pump, and control group received an equal volume of ph- ysiologic saline. On the 1, 3 and 5 days after operation, serum concentrations of BUN and crearinine were detected by automated chemical analyzer. Histological(hematoxylin-edsin, periodic acid Schiff, trichrome, reticulin and epon-toluidine blue stains) and enzyme histochemical(adenosine triphosphatase, succinic dehydrogenase, and acid phosphatase stains) studies were also performed. The following results were obtained. 1. Serum BUN and creatinine levels were significantly increased in control group proportional to the postope- ration course. But there was no increase in dimethyl sulfoxide treated group except slightly elevated BUN le- vel of 1 day group after operation. 2. The control group exhibited prominent morphological changes including irregular dilatation of tubules, va- cuolar degeneration, detachment and necrosis of proximal tubular epithelium, numerous hyaline casts in distal cation of proximal tubular epithelium. And these morphologic changes were increased progressively in severity proportional to the post-operation course. However, dimethyl sulfoxide treated group exhibited slight morpholo- gical changes including hyaline casts in tubules and vascular congestion except more prominent changes in 1 day group after operation. 3. On enzyme histochemical finding, adenosine triphosphatase, succinic dehydrogenase and acid phosphatase activities were diminished in control group, but not in dimethyl sulfoxide treated group.

Atherothrombotic Embolism을 동반한 Leriche 증후군

이영주,이재정,최창식,초문기 대한혈관외과학회 1988 Vascular Specialist International Vol.4 No.1

1) Acute ischemic change of left lower leg characterized by sudden pinkish blue discoloration, mottling, tenderness and numbness in aortoiliac occlusive disease was treated with thromboendarterectomy and aortic patch graft, distal Fogarty thromboembolectomy and ipsilateral lumbar sympathectomy. The result has been satisfactory with no episode of postoperative recurrence for seven months. 2) A discussion is made to the complication of atheromatous thromboembolism in completely occluded aortoiliac occlusive disease and the possibility of acute ischemic change of lower leg and foot. 3) A brief review is made on conceptional and patholgic basis of atheromatous microembolism and acute ischemic change secondary to relative large atheromatous embolism.

국회 예산심의액 증감의 영향요인에 관한 실증적 분석 : 예산결산특별위원회를 중심으로 Focusing on the Budget Committee

장문선,윤성식 한국정책학회 2002 韓國政策學會報 Vol.11 No.2

본 연구는 25년간의 시계열적 자료를 바탕으로 한국 국회 예산결산특별위원회 예산심의액 증감결정의 영향요인을 계량적으로 분석함으로써, 예산심의 영향요인으로 제시한 기존의 가설적 논의들을 검증하였다. 세출총액의 심의액 증감의 영향요인을 분석한 결과, 예결위 여당의원비율만이 유의미하여 당파적 영향에 의하여 예산액이 결정되는 것으로 드러났다. 또한 상임위의 예비심사와 예결특위 종합심사가 서로 상관성이 없는 것으로 분석되어, 다단계심사가 얼마나 비효율적인지 확인시켜주었다. 세출총액 분석에서는 한가지 변수만이 유의미하게 나타나, 독립변수들의 영향이 서로 상쇄되어 영향을 미치지 못한 것으로 판단됨에 따라, 예산심의액결정의 영향요인을 기능별 분류에 따라 분석하였다. 그 결과 예상대로 각각의 예산들은 예산심의에서 단편적인 요소에 의한 고려에 의해 이루어지는 것이 아니라, 정치, 경제, 행위자의 활동, 심의기간 등 여러 영향요인의 광범위한 고려에 의하여 이루어지는 것으로 나타났다. 또한, 경직성 예산인지, 비경직성 예산인지의 여부에 따라 각각의 영향요인들이 다른 방향으로 영향을 미쳤다. This study analyzes the effects of various determining factors on budget deliberation of the Korean National Assembly Budget Committee and tests previous hypotheses suggested by many scholars. It came to light that membership composition of the Budget Committee is the only significant factor in determining total expenditure amount. Multi-stage deliberation process was proved to ineffective in that there was no meaningful relationship between budget deliberations of the appropriation Committees and the Budget Committee. Since only one independent variable was proved to be significant in determining total expenditure amount, we analyzed the budget amount by functional classification. As we anticipated, several independent variables affects the amounts classified by functional category. Such factors as politics, economic conditions, the actions of the budget participants and deliberation period are found to be determining factors in budget deliberation. These factors affects the amount to a different degree depending on whether the budget amount is entitlement.

직장암의 수술전 방사선 단독치료군과 방사선-온열 병용치료군과의 임상적 및 병리학적 반응에 대한 비교 연구

문창우,김영호,염하용,정태식,장희경 高神大學 醫學部 1998 高神大學醫學部 論文集 Vol.13 No.1-2

부신피질자극호르몬과 성장호르몬의 결핍을 보인 1 예

문용,이영미,박창현,김지운,박찬웅,정만,류형선,심승식,천석배,강상구 대한내과학회 1993 대한내과학회지 Vol.45 No.4

Background: Combined ATCH and GH deficiency is a rare disease, Clinical and laboratory features are variable, non-specific and similar to those seen in adrenocortical insufficiency of any cause. Methods: We have exprienced a case of combined ACTH and GH deficiency without combined disease. The patient, 55 years old female, was admitted because of fatigue, nausea and vomiting on admission. Results: Serum sodium was 112 mmol/L, potassium 3. Hmmol/L, serum osmolarity 237m0sm,Kg and urine osmolarity 531 m0sm/Kg. Basal serum cortisol was 0.68 μg/ml, ACTH 12,7pgjml, GH below 0.1 ng/ml, basal urinary 17-hydroxycorticosteroid(17-OHCS) 0.5 μg/dl and blood glucose was 86 mg/dl. Although cortisol did not respond to rapid ACTH stimulation test, it responded to standard ACTH stimulation test. On combinded stimulation test, the cortis1 did not respond and all anterior pituitary hormone showed normal responses except ACTH and GH. In addition, plasma cortisol and ACTH repond to vasopressin test. There was no abnormalities in sellar CT, and hyponatremia was corrected dramatically with prednisolone replacement. Conclusion: Combined ACTII and GI-I deficiency is rare cause of secondary adrenocortical insufficiency, Its clinical manifestation similar to isolated ACTH deficiency in adult. Patients with isolated ACTFI deficiency due to suprapituitary dysfunction may be distinguished from those with intrinsic pituitary disease by stimulation of cortisol and ACTI-I secretion following vasopressin administration. More study needed to identify the definitive cause and hypothalamic-pituitary system.

진행된 위암의 온열 병용치료의 결과 : 59예의 대상환자 In cases of 59 patients

문창우,김영호,정태식,염하용,구자영 고신대학교 의학부 1998 高神大學校 醫學部 論文集 Vol.13 No.1-2

Purpose : This study is conducted to evaluate the local response rates and survival rates with median survival time(MST) following thermoradiotherapy or thermochemotherapy in locally advanced inoperable gastric cancer. Materials and Methods : 7 patients treated with thermoradiotherapy(RT+HT, Group Ⅰ) and 52 patients treated with thermochemotherapy(CTX+ HT, Group Ⅱ) were enrolled in this study. Hyperfractionated radiotherapy(l35cGy/fr., 2fr./day) using 6-10MV Linac was delivered to gastric mass and regional lymph nodes with total doses of 40.5-54Gy(median : 42.5 Gy). Chemotherapy with FI(5FU + Interferon) and EAP(Etoposide+Adriamycin+Cisplatin) regimens was administered. Hyperthermia using 8 MHz RF capacitive equipment (CANCERMIA GHT-8) was performed within 10-15minutes following irradiation, and simultaneously chemotherapy with 2 times/week, 40-60min./time. The estimation for local response rate was used computed tomography(CT) with/without endoscopic examination, and it was divided into complete response(CR), partial response(PR) and no response(NR) groups. The survival rate was calculated by Kaplan-Meier method. Results : Overall local response rate(CR+PR) was 67.8% (40 patients) with 5.1% (3 patients) in CR and 62.7%(37 patients) in PR. The local response rates by treatment modality was 100% (CR 14.3%, PR 85.7 %) in Group I and 63.4 % (CR 3.8%, PR 59.6%) in Group Ⅱ. There was no statistical significance. The local response rate by heating session was 64.2% (CR : 1.9%, PR : 62.3% in less than 7 session group and 100% (CR 33.3 % , PR : 66.7% in more than 8 session group. There was statistically significant difference(p=0.002). However, there were not statistically significant differences in comparison of local response rates by other factors(age, sex, heating temperature, chemotherapy regimen). Overall 1 and 2 years survival rates with MST were 25.4%, 15.9% with 8 months, respectively. The 1 and 2 years survival rates(MST) by treatment modality were 0%, 0% (6 months) in GroupⅠand 28.9%, 17.3% (8 months) in Group Ⅱ. There was statistically significant difference.(p=0.02). The 1 and 2 years survival rates (MST) by age were 0%, 0% (4 months) in less than 49 years Group and 29.4%, 17.7% (9 months) in more than 50 years group. There was statistical significance(p=0.013). However, there were no statistically significant differences in comparison of survival rates and MST by other factors(sex, heating session, heating temperature, chemotherapy regimen, response status). Two patients(3.4%) out of 59 patients experienced complications, and the most serious complication was subcutaneous fat necrosis. Conclusion : From this study we found that the local response rate was high in GroupⅠ, but the survival rate was high in Group Ⅱ. Therefore, it is concluded that thermo-chemo-radiotherapy is strongly recommended to increase local response rate and survival rate in locally advanced inoperable gastric cancer.

직장암의 수술전 방사선 단독치료군과 방사선-온열 병용치료군과의 임상적 및 병리학적 반응에 대한 비교 연구

문창우,김영호,염하용,정태식,장희경 고신대학교 의학부 1998 高神大學校 醫學部 論文集 Vol.13 No.1-2

Purpose : Authors studied to evaluate the clinical and pathologic responses of patients treated with preoperative radiotherapy alone and thermoradiotherapy for advanced and/or marginally resectable rectal cancer, retrospectively. Materials and Methods : Eight patients(57%) were treated with preoperative radiotherapy alone(Group Ⅰ), and 6(43%) were treated with thermoradiotherapy(Group Ⅱ) at department of Therapeutic Radiology, Kosin Medical College from Jan. 1990 to Dec. 1993. Hyperfractionated radiotherapy ( 135cGy/fr., 2fr./day, 10fr./week) was given by 6-10MV linear accelerator with total doses of 40.5-54Gy '(median : 42.75Gy), and RF-8MHz capacitive hyperthermic (CANCERMIA) treatment with intrarectal temperature range of 39.8-43.5℃ (median : 41.9℃) with interval of 2 times/wk, 40-60min./session, total 5-7 sessions was performed within 15-20 min. following radiation. Surgery was performed in 4 to 6 wks following radiation. Nine patients(64%) were performed by Miles' operation and 5(36%) by anterior resection. Results : Among 8 patients treated with preoperative radiation alone, 25% (2 patients) clinically downstaged after radiation, but 25% (2 patients) pathologically downstaged after operation, 37.5% (3 patients) upstaged. Among 6 patients treated with preoperative thermoradiotherapy, 50% (3 patients) clinically downstaged after thermoradiotherapy, but 16.7 % (1 patient) pathologically downstaged after operation, 50% (3 patients) upstaged. The major pathologic finding of surgical specimens was tumor necrosis increased. The average percentages of tumor necrosis out of total tumor mass determined by light microscope were 41.7% and 35% in Group Ⅰand Group Ⅱ, respectively. The rates of viable tumor cells determined by electromicroscope was 62.5% in Group Ⅰand 45% in Group Ⅱ. The rates of tumor volume reduction compared with initial tumor volume by physical examination, ultrasonograpy and CT was 52.1% in Group Ⅰand 69.4% in Group Ⅱ. Conclusion : From this study, it is concluded that preoperative thermoradiotherapy compared with preoperative radiotherapy didn't show any additive effects in pathological downstaging and tumor necrosis increased, but might be an additive effects in reduction of total tumor volume and viable tumor cell in advanced and/or marginally resectable rectal cancer.

백서에서 신 허혈성 손상에 미치는 칼슘 길항제의 효과

문철웅,정종훈,박천국,이승일,배학연,장경식,김만우,정춘해,홍순표,이병래,김호중 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

Renal ischemia is one of the most common causes of acute renal failure. Four factors related to the pathogenesis of acute renal failure are vasoconstriction, decreased glomerular filtration rate, tubular back leak of filtrate, and intratubular obstruction. The cellular response to renal ischemic insults include decreased content of adenosine trihosphate, lipid peroxidation induced membrane degradation, alteration in cellular pH, and calcium or phospholipase induced mitochondrial dysfunction. Much attention has been given to the role of increased cellular calcium as a pathogenetic contributor to cell injury during ischemia. Author studied the protective effects of calcium antagonists on cellular injury during renal ischemia in rat. To investigate the protective role of these agents, author measured the amount of malondialdehyde(MDA) and the enzyme activities of free radical scarvengers-superoxide dismutase(SOD), catalase and glutathione peroxidase from non-pretreated group and calcium antagonists pretreated groups in control, ischemia and reflow subgroups. The results were summerized as follows: 1) The amount of MDA in non-pretreated group was higher in the reflow compared with the control(<p<0.01). But, in all pretreated groups, there was no statistically difference in the amount of MDA. 2) The SOD activity in non-pretreated group was lower in both the ischemia and the reflow compared with the control (P<0.05). But, in both verapamil and trifluoperazine-pretreated groups, there was no statistically difference in the SOD activity. 3) Both catalase and glutathione peroxidase activities in non-pretreated group were lower in both the ischemia and the reflow compared with the control (P<0.05). But in all pretreated groups, there was no statically difference in both catalase and glutathione peroxidase activities. These results suggest that free radical mediated ischemic injury by renal artery clamp in rat can be protected by intraperitoneal pretreatment with calcium antagonists. As trifluoperazine has a protective effect in renal ischemia, the calcium activated calmodulin dependent enzyme may play a role in renal ischemic injury.