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Yun, Sun-Ung,Jung, Hai-Won,Cho, Byung-Yong,Choi, Byung-Joon,Lee, Baek-Soo,Kwon, Yong-Dae,Ohe, Joo-Young,Lee, Jung-Woo Korean Academy of Dental Science 2014 Journal of korean dental science Vol.7 No.1
Dentigerous cyst (DC) is an odontogenic cyst associated with the crown of an impacted, embedded, unerupted, or developing tooth. It is the second most common type of odontogenic cysts, accounting for 14% to 24% of all jaw cysts. Although these cysts occur more frequently during the second and third decades of life, they can also be found in children and adolescents in the mixed dentition stage. Treatment of the odontogenic cyst involves enucleation or marsupialization/decompression methods. The latter approach is preferred for larger cysts, and it is especially helpful in adolescent patients in conserving the unerupted permanent successors. The aim of treatment for DC is the complete elimination of pathology and maintenance of dentition with minimal surgical intervention. Recently defined criteria for the selection of treatment modality include the cyst size and location of the cyst, patient age, dentition involved, stage of root development, position of the tooth involved in the jaw, and relationship with the surrounding vital structure. Marsupialization or decompression technique has been advocated by several authors for treating DCs among young patients. In this conservative technique, the creation of an accessory cavity helps relieve intra-cystic pressure and accelerate the healing of cystic lesion. This technique has been successfully performed and is indicated for growing children and adolescents. Here, we report a large cyst lesion in the mandible treated by marsupialization for conservative management. In conclusion, successful reduction in size was achieved, and intraoperative complication could be prevented.
Ung-Kyu Choi,Hyun Su Ryu,Hyun Tae Kim,Sun Mi Yun,Su-Jin Lee,Jae Dek Choi,Young-Hyun Hwang,Soo Young Choi,Oh-Shin Kwon 한국식품과학회 2008 Food Science and Biotechnology Vol.17 No.5
This study was conducted to identify the differences in proteomic characteristics of ‘Agakong’, recombinant inbred line, and its parental genotypes ‘Eunhakong’ (Glycine max) and ‘KLG10084’ (G. soja). The isoflavone content of ‘Agakong’ was 3 times higher than that of its parental lines. A combined high-throughput proteomic approach was employed to determine the expression profile and identity of proteins using 2-dimensional gel electrophoresis and matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry. The overall distribution patterns of proteins are quite similar, but lots of protein spot intensities varied among the genotypes. A total of 41 proteins, representing significant difference in the quantities of protein among the lines, were successfully identified. Among them, more than 50% of the proteins identified were subunits of glycinin and β-conglycinin, 2 major storage proteins. This study showed that the proteomic analysis could help to define specific changes in protein level and composition, which can occur in the generation of new soybean varieties.
A Study on the Load and Deformation of Race Carbon Bicycle Frame for Improved Athletic Performance
Ung Jae Choi(최웅재),Seung Ho Choi(최승호),Yong Sun Kim(김용선),Seong Min Yun(윤성민),Hong Gun Kim(김홍건) 한국기계가공학회 2019 한국기계가공학회지 Vol.18 No.1
As the industry develops and quality of life increases, the concept of leisure is also changing. Bicycling is a healthy sport for exercising while enjoying nature, facilitating the enjoyment of a healthy life. As a result, the awareness surrounding bicycles has increased, and so has the interest in lighter and more luxurious carbon bikes. The number of domestic companies producing carbon bicycles frames is nil. In this study, we analyze the frames of existing foreign brands and analyze the deformation and stress concentration area according to the load of the frame, using the finite element analysis. In addition, we set up the range of stiffness based on the content of the structural analysis, to localize the carbon bicycle frame and famous foreign products, and compare the prototype with the stiffness by using bicycle molds for track races.
조웅,오동선,윤영석 한국관광정보학회 2001 觀光情報硏究 Vol.- No.7
The tourist trade of Naju city in its present condition shows Naju's lack of interest as a central tourist attraction since 1997. In 1998 the tourist rate began to increase because of the interest in Naju's historical temples and the Bannam's tombs. This indicates the growing concern for cultural assets and national treasures in this area. The purpose of this research is to application Naju's cultural tourist trade and establish an image of Naju as a historical tourism city. The Application of cultural tourism resources should produce on a commercial scale tangible cultural assets to improve the historical sites and increase the tourist trade as well as to preserve the historical areas. In order to fulfill these tasks, it is necessary to application cultural resources and assets to maintain all historical areas such as fortress, pavilions, temples and tombs, and utilize local temples as spiritual, moral and cultural foundations. Therefore It is very importment task What tour in Naju means, How we develop and preserve this report intend to suggest a direction of application in cultural tour resoureces with the case of Naju, especially in this moment that each reginal self governing parties is developing the cultural tour resource vigorously
Ki Ung Kang(강기웅),Jun Young Oh(오준영),Yun Ha Lee(이윤한),Hye Sun Lee(이혜선),Seo Yeon Jin(진서연),Sun Sik Bae(배순식) 한국생명과학회 2018 생명과학회지 Vol.28 No.12
죽상동맥경화는 대동맥의 만성염증에 의해 주로 발병되는 폐쇄동맥질환이다. 혈관평활근세포의 증식 및 이동은 죽상동맥경화 발병의 주된 병리적 반응이다. 본 연구에서는 죽상동맥경화 발병기전을 유도하는 표적 염증반응물질의 탐색 및 이들에 의한 신호전달 기전을 연구하였다. 혈관평활근세포의 증식 및 이동은 prostaglandin F2α (PGF2α)에 의해 의미 있게 증가하였으나 tumor necrosis factor α (TNFα)에 의해서는 증가하지 않았다. Prostacyclin I₂ (PGI₂)는 혈관평활근세포의 증식은 촉진시켰으나 이동은 오히려 억제하였다. prostaglandin D₂ (PGD2) 및 prostaglandin E₂ (PGE₂)는 혈관평활근세포의 증식을 촉진시켰으나 이동에는 영향을 미치지 않았다. PGF2α는 용량 의존적으로 혈관평활근세포의 증식 및 이동을 촉진시켰고 EC50는 약 0.1 μM로 관찰되었다. 혈관평활근세포에서 phospholipase C-β3 (PLC-β3) 아형의 발현은 매우 높았으나 PLC-β1, PLC-β2, 및 PLC-β4의 발현은 관찰되지 않았다. U73122 처리를 통해 PLC의 활성을 억제하면 PGF2α에 의한 혈관평활근세포의 이동이 억제되었다. 또한 PLC-β3의 발현을 억제하면 PGF2α에 의한 혈관평활근세포의 증식 및 이동이 억제되었다. 이러한 결과들을 바탕으로 PGF2α 는 혈관평활근세포의 증식 및 이동에 중요한 역할을 수행하고, 여기에는 PLC-β3가 필수적인 역할을 담당하고 있음을 제안한다. Atherosclerosis is an obstructive vessel disease mainly caused by chronic arterial inflammation to which the proliferation and migration of vascular smooth muscle cells (VSMCs) is the main pathological response. In the present study, the primary responsible inflammatory cytokine and its signaling pathway was investigated. The proliferation and migration of VSMCs was significantly enhanced by the prostaglandin F2α (PGF2α), while neither was affected by tumor necrosis factor α. Prostacyclin I₂ was seen to enhance the proliferation of VSMCs while simultaneously suppressing their migration. Both prostaglandin D₂ and prostaglandin E₂ significantly enhanced the migration of VSMCs, however, proliferation was not affected by either of them. The proliferation and migration of VSMCs stimulated by PGF2α progressed in a dose-dependent manner; the EC50 value of both proliferation and migration was 0.1 μM. VSMCs highly expressed the phospholipase isoform C-β3 (PLC-β3) while others such as PLC-β1, PLC-β2, and PLC-β4 were not expressed. Inhibition of the PLCs by U73122 completely blocked the PGF2α-induced migration of VSMCs, and, in addition, silencing PLC-β3 significantly diminished the PGF2α-induced proliferation and migration of VSMCs. Given these results, we suggest that PGF2α plays a crucial role in the proliferation and migration of VSMCs, and activation of PLC-β3 could be involved in their PGF2α-dependent migration.