서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

Apoptotic Effect of Co-treatment with Chios Gum Mastic and HS-1200 on G361 Human Melanoma Cell Line

Young-Joo Hur,Young-Ki Kim,Hyun-Ho Kwak,Gyoo-Cheon Kim,Seung-Eun Lee,In-Ryoung Kim,Chul-Hoon Kim1,Bong-Soo Park 대한해부학회 2009 Anatomy & Cell Biology Vol.42 No.2

Chios gum mastic (CGM) is a resinous exudate obtained from the stem and the main leaves of Pistacia lenticulus tree native to Mediterranean areas. Recently it reported that CGM induce apoptosis in a few cancer cells in vitro. Bile acids and their synthetic derivatives induced apoptosis in various kinds of cancer cells and anticancer effects. It has been reported that the synthetic chenodeoxycholic acid (CDCA) derivatives showed apoptosis-inducing activity on various cancer cells in vitro. This study was undertaken to investigate the synergistic apoptotic effect of cotreatment with a natural product, CGM and a CDCA derivative, HS-1200 on G361 human melanoma cells. To investigate whether the co-treatment of CGM and HS-1200 compared with each single treatment efficiently reduced the viability of G361 cells, MTT assay was conducted. To investigate augmentation of apoptosis in G631 cells co-treated with CGM and HS-1200, DNA electrophoresis, Hoechst staining, proteasome activity assay, flow cytometry, Westen blot analyses, immunofluorescent staining and confocal microscopy were performed. In this study, G361 cells co-treated with CGM and HS-1200 showed several lines of apoptotic manifestation such as nuclear condensations, DNA fragmentation, the reduction of MMP and proteasome activity, the decrease of DNA content, the release of cytochrome c into cytosol, the translocation of AIF and DFF40 (CAD) onto nuclei, activation of caspase-9, caspase-3, PARP and DFF45 (ICAD), and up-regulation of Bax whereas each single treated G361 cells did not. Although the single treatment of 40 μg/mL CGM or 25 μM HS-1200 for 24 hrs did not induce apoptosis, the co-treatment of them induced prominently apoptosis. Therefore, combination therapy of CGM and HS-1200 could be considered, in the future, as an alternative therapeutic strategy for human melanoma.

최근의 대학 교양영어 교재에 대한 어 · 문학적 고찰

김봉주,신성철,유재익 충남대학교 인문과학연구소 1974 인문학연구 Vol.1 No.1

It is true that the general English textbooks which the Korean colleges and universities use recently have considerably improved for the past thirty years; but still, some of them are edited and published without any good principle. To reflect our attitude toward the compilation of textbooks, we review here some of the readers and laboratory workbooks which are used recently at the ten institutes we have chosen at random. Ten kinds of textbooks that we could collect are for reading, and eight for laboratory. The purpose of learning general English in college is to attain a basic knowledge of English that educated men should have in common and to foster the ability to comprehend the students major textbooks. Someone emphasize hearing or speaking rather than reading English. But in Korea we can not help emphasizing reading. If possible reading and speaking are expected to be well-balanced in learning. To fulfil the above mentioned purpose a suitable textbook of English for college students must be considered from the linguistic and literary point of view. So in this paper we investigate each of the ten colleges' books and found out the following characteristics : (1) The colleges are trying to pay attention to the compilation of better textbooks. (2) The simple style of the books is changing into a comparatively complex one. (3) They show a tendency to avoid taking special literary works only and to include some essays or many varieties of writings. (4) They put emphasis not only upon written English but also upon spoken English. (5) Most of the lessons in those books possess cultural and practical value. (6) Most of the lessons have remarkable notes and exercises. We would like to make following suggestions: (1) Compilers should study every unit more carefully. (2) Textbooks should be systematical. (3) The content of a book had better be a such one that students are interested in. (4) Archaic passages should be replaced with fresh ones. (5) Many varieties of contents should be taken. (6) Compilers and publishers must be conscientious.

흰쥐 중추신경계내 난소로 투사하는 미주신경로에 관한 연구

김명주,장명세,고미희,노해숙,조해영,오문유,이봉희 濟州大學校 基礎科學硏究所 2001 基礎科學硏究 Vol.14 No.1

본 실험은 부교감신경의 하나인 미주신경이 난소를 지배하는 신경으로 관여하고 있는지를 pseudorabies 바이러스를 이용하여 난소신경로와 난소주사후 미주신경절단을 통하여 조사한 연구 보고이다. 이를 위하여 Sprague Dawley계 암흰쥐를 대상으로 pseudorabies 바이러스를 난소에 주사한 무리와 난소 주사후 미주신경을 절단한 무리에서 뇌를 적출하여 pseudorabies 바이러스에 대한 면역조직화학 염색을 시행하여 비교하였다. 본 실험결과 미주신경 중추신경로내의 상위신경핵들이 pseudorabied 바이러스에 대하여 양성반응이 줄어들었거나 관찰되지 않는 차이를 보였다. 즉 적색핵, 종말판혈관기관, 줄무늬체, 침상핵과 이마엽겉질은 부분적으로 난소의 미주신경로에 관여하고 있으며 미주신경등쪽핵, 고립로핵, 최후영역, 청색반점, 팔옆핵, 코리케퓨즈핵, 흑색질 및 시각교차위핵은 양성반응이 관찰되지 않아 미주신경으로 투사하는 부교감신경핵으로 조사되었다. The mammalian ovary has been known as receiving its innervation by sympathetic and sensory neurons of the peripheral nervous system from the brain. Recently, there were several functional reports that the vagus nerves were also regulating the ovarian function, but the vagus nerve had not been identified by clear morphological evidence. A viral transneuronal tracing technique has been used to demonstrate the morphological evidence for the central vagal involvement in ovarian innervation in brain areas. Bartha strain of pseudorabies virus injection was made into the ovary of Sprague Dawley rats. In experimental group, the vagus nerve of the same injection side was removed right after ovarian injection. At five days after initial injection, all the rats were sacrificed and brains were processed for immunohistochemistry. Several central nuclei including hypothalamic paraventricular nucleus showed strong bilateral positive labelings after unilateral injection in control rats, but the positive labelings were disappeared or decreased in several hypothalamic nuclei and nuclei of the vagus nerve. I n conclusion, these results provide the morphological evidence that vagus nerve has neural connection to ovary and by which the central nervous system may maintains the state of ovulation and reproduction as a possible parasympathetic routes in mammals.

S 環境에서 地圖 資料의 活用

金熙載,金捧柱 慶星大學校 1994 論文集 Vol.15 No.2

The purpose of this paper is a construction about 2 dimensional array with a line data set by selecting co-ordinates data set from given PCX file for map. The map graph is generated from constructed array and is reconform to user function on S envirnment.

기의 과학적 연구

김봉주 한국정신과학학회 1999 韓國精神科學學會誌 Vol.3 No.2

동양철학자들은 일찍부터 우주만물의 궁극적 구생원료는 기라는 견해를 견지해왔다. 그럼에도 서양과학자들은 아직껏 그 설을 쾌히 받아들이지 않고 있는 실정이다. 이에 기가 우주구성의 궁극적 질료로서 그것이 어떻게 만물을 생성하는가를 과학적으로 밝히고자 한다. Oriental philosophers have long before had a view that an ultimate an material of which the universe is composed is 'ki'. Western scientists, however, have never accepted this view yet. So here we scientifically examine theory of 'ki' I. e an ultimate energy-material(UEM), and identify how it generates all things in me universe.

직렬 리액터를 이용한 계통연계형 태양광 발전 시스템

金大均,鄭春炳,全基英,李丞煥,吳鳳煥,李勳九,金容珠,韓慶熙 명지대학교 산업기술연구소 2005 産業技術硏究所論文集 Vol.24 No.-

Since the residential load is an AC load and the output of solar cell is a DC power, the photovoltaic system needs the DC/AC converter to utilize solar cell. In case of driving to interact with utility line, in order to operate at unity power factor, converter must provide the sinusoidal wave current and voltage with same phase of utility line. Since output of solar cell is greatly fluctuated by insolation, it is necessary that the operation of solar cell output in the range of the vicinity of maximum power point. In this paper, DC/AC converter is three phase PWM converter with smoothing reactor. And then, feedforward control used to obtain a superior characteristic for current control and digital PLL circuit used to detect the phase of utility line.

潛在意味

金鳳柱 충남대학교 어학연구소 1980 언어 Vol.1 No.-

여가스포츠 참여에 따른 주부의 건강증진 생활방식의 변화

김은주,권봉안 韓國體育大學校附屬 體育科學硏究所 1998 韓國體育大學校附屬 體育科學硏究所論文集 Vol.17 No.1

The propose of this study was to indentify the relationship between housewives of leisure activity and life pattern for the improvement of health. The subjects of this study were selected using the random cluster sampling method. To achieve this purpose, people together who live in Seoul as monitors, then to be samples who goes to gym which is placed Kyung-gi area. We selected two of gyms in each areas randomly totally 8 gyms, and then considered the rate of participants per unparticipants to make 480 samples from collecting 60 samples from each areas. We obtained the knowledge form rolling paper that ask whether being active in sports or not and how many times being active in sprots and measured the life pattern for being healthy with the rolling paper which is developed by Walken, Sechrist and Pender(1987)and updated by Seo, Yun-Ok. To statistical methods utilized in this study for analyzing the collected data were reliability analysis, descriptive statistics, analysis of covariance, multiple classification analysis and standard multiple regression analysis. From the analyses of data, this study reached the following conclusion: Firstly, there are partially differences between the leisure activities of housewives and the life pattern for being healthy which is by characteristic variable factors in statistics of population. There are no difference of degree of self-achievement and people relationship in each ears of age. However, the intensity of responsibility for health is high in 50 year of old the difference between the practice and nutrition is high in 40 year of old, and the treatment of stress is high in 30 year of old. The difference of life pattern for being healthy by the existence of job effects only practice and nutrition and the difference of life pattern for being healthy by scholarship treat self-achievement and health-responsibility highly. The difference by religion shows the person who have own religion have stronger responsibility than the person who do not have. The rage of self-achievement, health responsibility, practice and nutrition is high in high-income and the person who gas many number of children shows high health responsibility, people-to-people relationship, self-achievement, practice and nutrition. Secondly, there os a difference of life style for health-improvement from housewife's participation of leisure sports. The desire of self-achievement of participant is higher than unparticipant, but it is not affect to participant leisure sports. Therefore as a result of above, as much as the housewives attention in leisure sport activities, the degree of nutrition.

意味生成에 關한 硏究

金鳳柱 충남대학교 인문과학연구소 1975 인문학연구 Vol.2 No.1

This study attempts to characterize how the meaning of a word may undergo change or generate various meamings in contexts, but still retain some features or vestige of its original meaning. For instance, man, which means a general person in the lexicon, has become specialized as paraphrased in the following classical examples: My man (=husband) is not at home. They are the King's men (=servants), He is an Oxfordman(=student). Or a word may acquire a figurative meaning as man in She is a man (=manly), eye in the eye of a needle, or hand in the hands of a clock. Thus primary meaning is taken here as the material with which the various peripheral meanings are generated, either connotatively or denotatively. For example, deer, whose meaning has been tremendously specialized, since Old English times, still retains the meaning 'animateness', the various tables in the contexts such as the table for breakfast, the time table, and the table of contents have the meaning 'flatness'. The polysemical use of a word comes from association; we associate cattle with cow, bull, horn, rumination, slow, dull, etc., as exemplified in Tom's cattle are bullfighters, My reminiscence of her is always of cattle, or You are cattle! The field of association is a device for generating meaning. Compounding or making phrases or wordgroups, is another device for it, e. g., lion-hunting, blood-let, kill-joy, dark-blue, whitewash, noble man, take part in, a very pretty girl, his safe arrival. These devices make it possible for us to generate countless meanings with a small number of symbols(words). Therefore, it is assumed here that some words have a more powerful generative capacity than others, because they are basic in terms of structural importance, i. e., semantic field and frequency. C. K. Ogden's Basic English, which is widely regarded as basic in this sense, is used as the source materials for this study. And in redefining or rephrasing, I selected 142 words as sememes from his 850 vocabulary items, and then tested their reproductive (generative) capacity by using the 142 words.