기능성 소화불량증환자에서 Winstal® 투여에 관한 임상경험

이창형,김영탁,금민수,권중구,안병철,윤영미,권영오,김성국,최용환,정준모 慶北大學校 醫科大學 1994 慶北醫大誌 Vol.35 No.3

목적 : 기능성 소화불량증은 소화, 흡수등 장관의 기능적인 이상과 관련되어 있을 것으로 생각되며 복합소화효소제(Winstal®)를 투여하여 그 임상효과를 평가하고자 본 연구를 실시하였다. 대상 및 방법 : 1994년 3월 부터 6월까지 경북대학교병원 내과를 방문한 기능성 소화불량증을 호소하는 환자 20명을 대상으로 Winstal®을 1회 1정씩, 1일 3회 식후 30분내에 경구로 2주간 투여하였다. 결과 : 소화불량증의 증상은 복부불쾌감, 복부팽만감, 식욕부진 및 오심, 복부동통, 공기연하증, 고창 및 구토순이었으며, 증상의 개선은 복부불쾌감이 76.4%(13/17)로 가장 높았으며, 그 다음으로 복부팽만감 및 공기연하증이 66.5%(10/15, 6/9)이었고, 오심 61.5%(8/13), 식욕부진 53.8%(7/13), 복부동통 41.6%(5/12), 고창 37.5%(3/8)이었다. 각 환자별 종합적인 증상의 개선도는 현저한 개선이 2예(10%), 중등도 개선이 3예(15%), 약간개선이 11예(55%), 불변이 4예(20%)이었으며 종합적인 유효율은 80%(16/20)이었다. 부작용은 한 예에서도 관찰되지 않았다. 결론 : 본 제제는 기능성 소화불량증 환자의 증상개선에 추천할 만한 유효한 약제로 생각된다. Dyspepsia is a common symptom in gastroenterologic practice and trigger for numerous consultations with physician. The treatment of chronic functional dyspesia is unsatisfactory. This study was performed to evaluate the efficacy of the digestive compound (Winstal®) on 20 functional dyspepsia patients. On open trial, all patients were given 6 tablets daily for 2 weeks and we evaluated the efficacy of this preparation according to the degree of the improvement. The improvement of symptoms was 76.4%(13/17) in abdominal discomfort, 66.5%(10/15, 6/9) in abdominal distension and aerophagia, 61.5%(8/13) in nausea, 53.8%(7/13) in abdominal pain, and 37.5% (5/12) in flatulence, respectively. Overall effectiveness of subjective symptoms was 80% (16/20) and there were no untoward effects of the preparations during this study. As a result, We think that this preparation is an effective one to relieve symptoms of functional dyspepsia.

FDM에서 경사면의 표면과 면적오차법의 관계에 대한 연구

전재억,정진서,황영모,김수광,김준안,계중읍,하만경 한국공작기계학회 2002 한국공작기계학회 추계학술대회논문집 Vol.2002 No.-

In any rapid prototyping process, the layer by layer building process introduces an area error between the staircase and the surface line specified by the computer-aided design model. This affects the dimensional accuracy as well as the surface finish for different part build orientations. This paper describes a methodology for computing the area error for any orientation of the part built by the fused deposition modelling system. This technique can be applied to determine the best build orientation of the part, based on the minimum area error. This technique is verified by comparing the results with the experimental measurements of the area error of the parts built at different orientations.

염증성 근병증에서 자기공명영상의 임상적 의의

고재현 ( Jae Hyun Koh ),홍석주 ( Suk Joo Hong ),안홍준 ( Hong Joon Ahn ),안중경 ( Joong Kyung Ahn ),전찬홍 ( Chan Hong Jeon ),차훈석 ( Hoon Suk Cha ),안중모 ( Joong Mo Ahn ),김현숙 ( Hyun Sook Kim ),서연림 ( Yeon Lim Seo ),고은미 대한류마티스학회 2002 대한류마티스학회지 Vol.9 No.3

Objective: The purpose of the study is to describe the magnetic resonance imaging (MRI) findings and to investigate useful sequences of MRI in inflammatory myopathies. A third goal is to correlate MRI findings with the grade of histopathologic severity. Methods: Sixteen patients (13 women, 3 men), aged 21~74 years (median age of 49) with inflammatory myositis (examined with both MRI and muscle biopsy) were studied. Ten patients were diagnosed with polymyositis and 6 with dermatomyositis. Conventional T1-weighted (SE 366/12) and T2-weighted (SE 4766/90) fast spin-echo and fat-suppressed T1-weighted MR images with contrast enhancement (FSAT T1 CE) were obtained. Ratios between the signal intensities of a muscle and the signal intensities of subcutaneous fat in the same tomographic sections were calculated to objectively represent the degree of signal intensities. Semi-quantitative grading of severities in muscle biopsy specimen was examined based on invasion of inflammatory cells and necrosis, degeneration and regeneration of muscle fiber by a neuromuscular pathologist. Results: FSAT T1 CE could objectively describe the severity of involvement in inflammatory myopathies. The quadriceps muscle group, especially the vastus muscle tended to be most severely and frequently involved in inflammatory myositis with FSAT T1 CE (statistically insignificant). The vastus intermedius muscle was more severely involved in dermatomyositis than polymyositis. The signal intensity of abnormal muscle sampled by biopsy correlated positively with the grade of muscle biopsy. Conclusion: MRI shows promise in identifying pathologic muscle in patients suspected of having one of the inflammatory myopathies. The degree of signal intensity on MRI may reflect the severity of grade in muscle biopsy.

전방 십자 인대 이식 건의 자기 공명 영상 소견과 이차적 관절경의 비교

안진환,홍석주,안중모,정윤성 대한슬관절학회 2002 대한슬관절학회지 Vol.14 No.2

목적 : 2차 관절경 검사로 증명된 잘 치유된 전방 십자 인대 이식 건의 자기 공명 영상 소견에 대하여 알아보고자 하였다. 대상 및 방법 : 1996년 6월부터 2001년 1월까지 동일한 수술자에 의해 관절경적 전방 십자 인대 재건술을 받은 419예 중, 술 후 MRI와 이차 관절경을 모두 시행 받은 29예의 술 후 MRI 33예(4예는 술 후 MRI를 2회 시행)를 대상으로 하였다. 성별 분포는 남자 18명, 여자 11명이었고, 연령 분포는 16세부터 59세, 평균 29.7세 이었다. 29예는 각각 자가 슬개건 15예, 자가 슬괵건 13례, 동종 슬개건 1예로 재건술을 시행받았다. 술 후 MRI 33여를 시행한 기간에 따라 3군(6개월 이내 7~12개월, 13개월이후) 으로 나누어 각 군간에 이식 근의 MRI 소견, 즉 이식 건의 신호 강도, 두께, 형태, 연속성, 경사 등이 차이가 있는지, 기간에 따른 변화가 있는지를 분석하였다. 자가 슬개건을 이용한 군(n=15)과 자가 슬괵건을 이용한 군(n=13) 간의 차이도 알아 보았다. 결과 : 33예의 술 후 MRI 중, 이식 건 내 증가된 신호 강도는 29예(87.7%), 이식 건의 형태는 세로 줄무뉘가 있는 경우가 27예 (81.8%), 부분 파열로 보인 예가 9예(27.3%), 느슨한 경사를 보인 예는 4예 (12.1%)이었다. 이식 건 내 신호 강도는 술 후 MRI를 시행한 기간이 길수록 감소하는 경향을 보였고, 이식 건의 시상면 두께는 기간이 길수록 증가하는 경향을 보였으나 통계적인 유의성은 없었다. 결론 : 전방 십자 인대 재건술 후 MRI에서 이식 건이 세로 줄무늬의 증가된 신호 강도를 보이고, 시간이 지날수록 신호 강도가 감소하며, 시상면 두께는 증가하는 경향이 있다. Purpose: To evaluate the postoperative MR findings of the healthy anterior cruciate ligament (ACL) grafts which were confirmed by the second-look arthroscopic examination. Materials and methods: Among 419 cases who underwent the arthroscopic ACL reconstruction by one operator between June 1996 and January 2001, we evaluated 33 MR scans of 28 patients who underwent the postoperative MR scan and the second-look arthroscopic examination (4 patients underwent postoperative MRI twice). There were 18 male and 11 female patients, and the patient's age ranges from 16 to 59 years-old (mean 29.7). There were 15 cases of autogeneous bone-patellar tendon-bone (BPTB) grafts, 13 cases of autogeneous double-loop hamstring grafts, and 1 case of allogeneous BPTB graft. Thirty-three MIRs were divided into 3 groups according to the time interval between operation and postoperative MR examination: less than 6 months, 7 to 12 months, and than 13 months. The MR findings of ACL grafts-signal intensity, morphology, continuity, orientation, diameter- were analyzed. Results: The increased signal intensity was found in 29 ACL grafts (87.7%) among 33 MR images. The most common pattern of the graft morphology was a longitudinal streak increased signal band (27 cases, 81.8%). The partial rupture was seen in 9 cases (27.3%), and the lax orientation in 4 cases (12.1%). According to Howell's scoring system, the signal intensity score of the graft tended to decrease with time after operation, and the sagittal diameter of the graft tended to increase with time after operation. Conclusion: The main MR finding of the healthy ACL graft was longitudinal streak increased signal band. The graft signal intensity seemed to decrease, and the sagittal diameter of the graft seemed to increase, as time passes after operation.

Multi-physics Analysis for Temperature Rise Prediction of Power Transformer

Ahn, Hyun-Mo,Kim, Joong-Kyoung,Oh, Yeon-Ho,Song, Ki-Dong,Hahn, Sung-Chin The Korean Institute of Electrical Engineers 2014 Journal of Electrical Engineering & Technology Vol.9 No.1

In this paper, a method for multi-physics analysis of the temperature-dependent properties of an oil-immersed transformer is discussed. To couple thermal fields with electromagnetic and fluid fields, an algorithm employing a user defined function (UDF) is proposed. Using electromagnetic analysis, electric power loss dependent on temperature rise is calculated; these are used as input data for multi-physics analysis in order to predict the temperature rise. A heat transfer coefficient is applied only at the outermost boundary between transformer and the atmosphere in order to reduce the analysis region. To verify the validity of the proposed method, the predicted temperature rises in high-voltage (HV) and low-voltage (LV) windings and radiators were compared with the experimental values.

Antimicrobial Effects of Flavone Analogues and Their Structure-Activity Relationships

( Jung Mo Young ),( Young Hee Park ),( Yong Uk Lee ),( Ho Jung Kim ),( Yhong Hee Shim ),( Joong Hoon Ahn ),( Yoong Ho Lim ) 한국미생물생명공학회 2007 Journal of microbiology and biotechnology Vol.17 No.3

만성 간질환 환자에 있어서 간초음파소견과 간조직검사와의 비교

권중구(Joong Gu Kwean),이창형(Chang Hyung Lee),최성곤(Sung Gon Choi),이양일(Yang Il Lee),윤영미(Young Mee Yun),안병철(Byeong Cheol Ahn),최용환(Young Hwan Choi),정준모(Joon Mo Chung),박태인(Tae In Park),서인수(In Soo Seo),김기범(Ki Bu 대한소화기학회 1995 대한소화기학회지 Vol.27 No.2

N/A Background/Aims: Real time ultrasound scanning is accepted as the state-of-the-art imaging investigation in patients suspected with liver disease. In focal lesion, numerous studies have confirmed the accuracy of ultrasound scanning in diagnosis and this is also valuable in clinical management, In diffused parenchymal liver diseases, however, the diagnostic value of scanning in diagnosis is less valuable than focal disease. The aim of this study is to examine the clinical value of routine ultrasound examination in patients with parenchymal liver disease. Methods: The results of hepatic ultrasonography and hepatic histology in 278 patients that underwent liver biopsy between January l986 and December l992 were compared with the results ot routine ultrasound examinetion. All liver hiopsies were performed within I month of the ultrasonography. Results: Ultrasound examination revealed a sensitivity and specificity of 54% and 74%, in all cases. Ultrasound examination was highly sensitive for detecting fatty liver(81%) and similar sensitivity (64%) for cirrhosis but less sensitive for detecting chronic hepatitis(45%). Strong correlation was found between the degree of fatty change in histologically and the fine echo pattern of steatosis (p<0.001). Correlations was also between thc degree of hepatic fibrosis and echogenicity(p<0.001), hut hepatic inflammation, necrosis, and cholestasis had no significant correlation with echogenicity. Conclusions: Ultra.onography can be a useful tool in non-invasive prediction of liver histology in steatosis and cirrhosis, hut it is le.s useful in gauging hepatic inflammation, necrosis, and cholestasis. (Korean J Gastroenterol 1995;27: 199 - 205)

Recognition of Object ID marks in FA process from Active Template Model

Dong-Joong Kang,In-Mo Ahn,Tae-Jung Lho,Hyung-Keun An,Dong-Hun Yoo,Mun-Jo Kim 제어로봇시스템학회 2003 제어로봇시스템학회 국제학술대회 논문집 Vol.2003 No.10

유골 골종의 전산화단층촬영 유도하 경피적 고주파 열 치료의 성과 및 고찰

김정훈,AHN JOONG MO,이준우,이근영,이영준,오주한,조환성,강흥식 대한영상의학회 2015 대한영상의학회지 Vol.72 No.4

목적: 유골 골종의 치료에 있어 전산화단층촬영 유도하 경피적 고주파 열 치료의 효과를 보고하고자 한다. 대상과 방법: 2004년 5월부터 2013년 12월까지 본원 영상의학과에서 유골 골종으로 진단되어 전산화단층촬영 유도하 경피적 고주파 열 치료를 시행한 환자 31명[남자 23명, 여자 8명, 평균연령 20세(4~54세)]을 대상으로 하였다. 모든 시술은 3명의 근골격계 영상의학과 전문의 중 한 명에 의해 시행되었으며 치료 성적 평가를 위해 한 명의 영상의학과 의사가 대상 환자들의 의무기록과 영상을 후향적으로 분석하였다. 결과: 병변은 대퇴골(n = 20, 60%), 경골(n = 5, 15%), 비골(n = 2, 6%), 상완골(n = 3, 9%), 거골(n = 2, 6%), 종골(n = 1, 3%)에 위치하였다. 대부분 관절 외 병변이었으나(n = 27, 82%), 6건(18%)에서는 관절 내에 위치하였고 그 위치는 근위 대퇴골(n = 3, 50%), 거골(n = 2, 33%), 종골(n = 1, 17%)이었다. 퇴원 시점에서 33예 중 27예에서 통증의 완전 경감을 보였다(82%). 부작용은 3예에서 발생하였고 주요 합병증으로는 구획 증후군이 1예, 이 외에도 반응성 윤활막염과 가벼운 전극 삽입 부위 피부 화상이 각 1예씩 발생하였다. 최종 경과 관찰 시점에서 33예 중 27예에서 통증의 완전 경감을 보였으며(82%) 추가적인 합병증의 호소는 없었다. 결론: 유골 골종에서 전산화단층촬영 유도하 경피적 고주파 열 치료는 최소 침습적이고 안전한 효과적인 치료법이다. Purpose: To present the clinical outcome of computed tomography (CT) guided radiofrequency ablation (RFA) for osteoid osteoma. Materials and Methods: Thirty-one patients (M:F = 23:8, mean age: 20 years, range: 4–54 years) who underwent RFA for clinically suspected osteoid osteoma from May 2004 to December 2013 were retrospectively reviewed. RFA was done in all cases under CT guidance by one of three radiologists in our department. Electronic medical records and images were retrospectively reviewed in all patients. Results: Lesions were located in femur (n = 20), tibia (n = 5), fibula (n = 2), humerus (n = 3), talus (n = 2), and calcaneus (n = 1). On discharge, 27 of 33 cases showed complete remission of pain (82%). One major complication (compartment syndrome) and 2 minor complications (reactive synovitis, minimal skin burn at electrode insertion site) were observed. On the last follow-up (0–78 months, mean: 12.6 months) 27 of 33 cases were successfully treated (82%) and had no more complaints. 3 cases presented remaining pain (9%). In 3 cases relapse occurred (9%) and RFA was repeated in 1 case. The repeated treatment was successful. Conclusion: CT-guided RFA is an effective method for the treatment of osteoid osteoma.

Recognition of Patterns and Marks on Monitor Glass Panel

In-Mo Ahn,Kee-Sang Lee,Dong-Joong Kang 제어로봇시스템학회 2002 제어로봇시스템학회 국제학술대회 논문집 Vol.2002 No.10