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만성 간질환 환자에 있어서 간초음파소견과 간조직검사와의 비교
권중구(Joong Gu Kwean),이창형(Chang Hyung Lee),최성곤(Sung Gon Choi),이양일(Yang Il Lee),윤영미(Young Mee Yun),안병철(Byeong Cheol Ahn),최용환(Young Hwan Choi),정준모(Joon Mo Chung),박태인(Tae In Park),서인수(In Soo Seo),김기범(Ki Bu 대한소화기학회 1995 대한소화기학회지 Vol.27 No.2
N/A Background/Aims: Real time ultrasound scanning is accepted as the state-of-the-art imaging investigation in patients suspected with liver disease. In focal lesion, numerous studies have confirmed the accuracy of ultrasound scanning in diagnosis and this is also valuable in clinical management, In diffused parenchymal liver diseases, however, the diagnostic value of scanning in diagnosis is less valuable than focal disease. The aim of this study is to examine the clinical value of routine ultrasound examination in patients with parenchymal liver disease. Methods: The results of hepatic ultrasonography and hepatic histology in 278 patients that underwent liver biopsy between January l986 and December l992 were compared with the results ot routine ultrasound examinetion. All liver hiopsies were performed within I month of the ultrasonography. Results: Ultrasound examination revealed a sensitivity and specificity of 54% and 74%, in all cases. Ultrasound examination was highly sensitive for detecting fatty liver(81%) and similar sensitivity (64%) for cirrhosis but less sensitive for detecting chronic hepatitis(45%). Strong correlation was found between the degree of fatty change in histologically and the fine echo pattern of steatosis (p<0.001). Correlations was also between thc degree of hepatic fibrosis and echogenicity(p<0.001), hut hepatic inflammation, necrosis, and cholestasis had no significant correlation with echogenicity. Conclusions: Ultra.onography can be a useful tool in non-invasive prediction of liver histology in steatosis and cirrhosis, hut it is le.s useful in gauging hepatic inflammation, necrosis, and cholestasis. (Korean J Gastroenterol 1995;27: 199 - 205)
최성곤(Sung Gon Choi),김영탁(Young Tak Kim),금민수(Min Su Geum),이양일(Yang Il Lee),권중구(Joong Gu Kwean),이창형(Chang Hyeong Lee),권영오(Young Oh Kweon),김성국(Sung Kook Kim),최용환(Young Hwan Choi),정준모(Joon Mo Chung) 대한소화기학회 1996 대한소화기학회지 Vol.28 No.3
The raw carp bile has been known as having both nephrotoxic and hepatotoxic effects which mechanisms are not well-known. Review of previously reported literature revealed many cases that had clinical evidences of both hepatitis and renal failure but any case of isolated hepatitis without acute renal failure was not found. We experienced a case of acute toxic hepatitis without evidence of renal failure due to ingestion of raw carp bile, so we report this case with review of literature. (Korean J Gastroenterol 1995;28: 421 - 425)
정준모(Joon Mo Chung),최용환(Yong Hwan Choi),탁원영(Won Young Tak),윤영미(Young Mee Yun),이양일(Yang Il Lee),최성곤(Sung Gon Choi),권중구(Joong Gu Kwean),이창형(Chang Hyung Lee),안병철(Byeong Cheol Ahn),곽규식(Kyu Shik Kwak) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.4
N/A Esophageal carcinoma carries an extremely poor prognosis. Despite advances in medical technology, survival rates after diagnosis remain dismal. This report was attempted to analyse the survival rate and affecting factor in 76 cases of esophageal carcinoma patients. They received various modalities of treatment, and the median sruvival for each treatment group was 10.9 months in combined radiotherapy and chemotherapy (27 cases), 6 months in radiotherapy alone (10 cases), 13 months in combined therapy including surgery (20 cases), 4.5 months in chemotherapy alone (6 cases), and 5.7 months in conservative therapy (13 cases) (p< 0. 05, Peto-Wilcoxon method). The median survival by stage was 20. 7 months for stage I, 11. 2 rnonths for stage II, 6.9 months for stage III, and 5.7 months for stage lV (p<0.05, Peto-Wilcoxon method). Using survival as an outcome, a Cox-multivariate analysi was performed looking at age, location of lesion, length of lesion, TNM stage, type of treatment, hemoglobin level, albumin level, and weight loss. This analysis revealed significant predictors for increased survival, which were type of treatment and TNM stage (p<0.05). We concluded that the significant factors affecting the survival in esophageal carcinoma were treatment strategy an TNM stage.
정준모,최용환,권영오,권중구,이죽내 대한소화기학회 1998 대한소화기학회지 Vol.32 No.3
Background/Aims, Many studies have revealed evidences supporting that the incidence and the mortality of patients with alcoholic liver disease resulting from alcohol abuse have been increased in Korea. However, there is a lack of research considering the psychological factors in patients with alcoholic liver disease. Consequently, this study was designed to evaluate the demographic characteristics, drinking patterns and psychologic symptoms of the patients with alcoholic liver disease. Methods: Structured questionnaire and symptom cheek list-90-revision (SCL-90-R) were used for groups with alcoholic liver disease and alcohol dependence. Results: There were striking differences in socio-demographic characteristics, marital problem (patient and parent), psychopathology of family members and drinking pattern between the groups of alcoholic liver disease and alcohol dependence. The resulting scores for 4 parameters (obsessive-compulsive, sensitivity, anxiety, hostility) were higher in the group of alcoholic liver disease than in alcohol dependence (P$lt;0.05, P$lt;0.01, P$lt;0.01, P$lt;0.05). Conclusions: For the management of the patients with alcoholic liver disease, the psychopathology of the patients should be considered.