만성 재발성 소아 흉통의 원인 질환과 임상양상

최은정,이은아,이창우,최두영,오연균,김종덕,윤향석 대한소아과학회 2004 小兒科 Vol.47 No.6

오렌지로부터 아플라톡신B₁의 정량분석에 관한 연구

장향동,백광균,구경림,옥선미,최진석,고은주,류성렬 한국공업화학회 2004 응용화학 Vol.8 No.2

Aflatoxin B₁ was known to have the strongest poisonous character among Aflatoxin compounds. To search the production of Aflatoxin B1 according to the change of temperature, relative humidity and incubation days, orange incubated with Aspergillus parasiticus KCCM 35078 was incubated at 20℃, 25℃, 30℃ at relative humidity 60%, 70%, 80% and for incubation time 3, 4, 5, 6, 7 days.. Production of Aflatoxin B₁ shows that the highest production appeared at 25℃ and its relative humidity 70%. The result that was quantitatively analyzed by using HPLC was 77.41ppm, and by using Fluoroscence detector was 87.87ppm. - Production of Aflatoxin B₁ shows that the lowest production appreared at 20℃ and its relative humidity 80%(HPLC), 60%(Fluoroscence detector). The result that was quantitatively analyzed by using HPLC was 4.47ppm, and by using Fluoroscence detector was 4.17ppm. The structure of Aflatoxin B₁ was identify with authentic sample by using instrumental analysis methods of GC/MS, ¹H-NMR, FT-IR respectively.

소아 급성 신우신염환아의 색도플러 초음파 검사의 유용성

김은미,권귀향,이혜경,홍현숙,최득린 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1

Purpose: Urinary tract infections are common in childhood and are most frequent in those under 1 year of age. In these children, however, differentiation of the pyelonephritis from cystitis is clinically difficult. We investigated the utility of color doppler image ultrasound in the diagnosis of acute pyelonephritis(APN) in children. Results were compared with renal cortical scintigraphy using 99mTC-DMSA. Materials and Methods : 99mTc-DMSA SPECT and color doppler ultrasound were performed within 1 week intervals in 14 patients with clinically suspected APN. (aged 4months to 15years: mean 6.1 year, 7 girls and 7boys). Urine culture was considered positive if greater than 100.000 colonied of a single organism were isolated. CDI was performed with 3.5NHz convex linear probe Ultramark 9(ATL., Bothell, Washington, USA) following a standard gray scale sonogram of the kidneys. Renal cortical scintigraphy was performed with 99mTc DMSA SPeCT(PRISM 2000, Picker, USA), Axial, coronal, both sagittal pinhole images were obtained 1.5-2 hour after 1mCi isotope was injected. Renal scan was considered to be abnormal and indicative of APN when there was a focal, wedged shaped defect in radionuclide accumulation extending from the periphery of the kidney to centrally or if there was diffuse abnormality in renal tubular function. Renal scarring was defined when defects were shallow lesions along the periphery of the kidney with evidence of volume loss, or if they could be shown from prior examination to pre-date of the acute episode. The color doppler image were interpreted to be consistent with APN if there was decrease flows in the renal cortex. Results: Of the 28 kidneys were examined, renal scan showed 5 cases of abnomal findings, 3 cases were APN, 2 cases were chronic scarring. Two fo the three cases of APN showed decreased blood flow on CDI and positive culture, for a sensitivy 67%. Two cases of renal scarring due to grade V bilateral vesicoureteral reflux show decreased blood flow at right upper pole kidney on CDI, however DMSA scan had diffculties finding the new lesion due to underlying irregularity of scarred kidney. Color doppler US correctly identified 4 of 5 renal poles with APN and 21 of 23with no APN including 2 patients with false positive. The DMSA scan was used as the standard of comparison the study; the CDI has a sensitivity 67%, specificity 84%, positive predictive value 33%, negative predictive value 95%. 84% The lesion showed decreased blood flow and on one follow up case increased blood flow. The presence of prior renal scarring made interpretation of asymmetric vascularity difficult on DMSA, the use of CDI may increase the diabnostic sensitivity of sonography in pediatric pyelonephritis.

영․유아 그림 표상 특성에 관한 연구

이승옥,최은영,임지향 대구대학교 특수교육재활과학연구소 2005 再活科學硏究 Vol.23 No.2

The purpose of this study was to refer a symbolic characteristic of painting during scribbling period by applying a task condition, to present basic data about effective symbolic painting by analyzing a process of a construct activity, and to examine verification of effectiveness in the Korean infant. The one way anova is carried out to find out a symbolic characteristic of painting of Age(4)X group and the two way anova to Group(2)×Age(4), is conducted to figure out the difference of NC performance owing to task presented type upon age bracket. The followings were ostensive purposes of this study. First, there would be differences in symbolic characteristic by tasks and ages(the total score, the score of symbol inside the outline, the score of constituent, the score of pair symbolic). Second, the NC performance would differ in symbolic characteristic by age and painting type(the total score, the score of symbol inside the outline, the score of constituent, the score of pair symbolic). The study participants were randomly selected one - three years old infants (total of 80) who attend in an infant home in northern Daegu. They were divided in four groups. Each age group was presented two type of painting and multivariate analysis was taken in order to compare and analyze paintings. The result of this study was followed. First, the characteristic of painting symbol was different by task and age. The expressive ability in total score, constituent of object, pair symbolic in P task and DC task was increased as aging. Among the group of infants aged 1.5 - 2.5, P task was performed better than DC task, and the score of P task and DC task was equally heightened as they become age of 3. Second, NC performance owing to task presented type upon age bracket would be different (the total score, the score of symbol inside the outline, the score of constituent, the score of pair symbolic). The older has shown more expressive ability in two type of painting. NC task was taken after pre- P task and -DC task, but the symbolic score of NC task differed from. NC task followed by P task represented the more constituents and pair symbols than by DC task. Therefore, this study found out that the development of symbolic level in infant had close relationship with an age, the symbolic abilities in different painting tasks differed order of P task, DC task, and NC task, and symbolic painting was shown from infant age 1.5-2. 본 연구는 초기 그림 표상 출현과정을 살피기 위한 것으로 구체적인 가설은 다음과 같다. 첫째, 과제별 연령에 따른 그림 표상의 특성(총점수, 윤곽선 안의 표상의 점수, 대상의 구성요소 표상의 점수, 쌍표상의 점수)은 차이가 있을 것이다. 둘째, 연령별 과제 제시유형에 따른 NC과제 수행(총점수, 윤곽선 안의 표상의 점수, 대상의 구성요소 표상의 점수, 쌍표상의 점수)은 차이가 있을 것이다. 연구대상은 00시에 위치한 어린이집에 재원중인 1-3세 유아 총80명을 무선선정하여 연령별로 4집단을 나누고 각 연령집단별로 두 그룹으로 나누어 서로 다른 유형의 과제를 실시하였다. 즉 한 그룹은 P과제 이후 NC과제를 실시하였고, 다른 한 그룹은 DC과제 이후 NC과제를 실시하였다. 과제실시 이후 각 과제에서 얻어진 표상그림을 채점하였다. 자료처리는 과제별 연령에 따른 그림표상의 특성을 살펴보기 위해 연령(4)x집단간의 일원 다변량분석을 실시하였고, 연령별 과제 제시유형에 따른 NC과제 수행의 차이를 보기 위하여 집단(2)×연령(4)에 대하여 2원 다변량분석을 실시하였다. 본 연구의 결과를 요약하면 다음과 같다. 첫째, 과제별 연령별에 따른 그림 표상의 특성은 차이가 있다. 연령에 따라 P과제 또는 DC과제 모두가 총점수, 대상의 구성요소, 쌍표상의 표현능력은 연령이 높음에 따라 표상능력이 증가함을 알 수 있었다. 1.5세-2.5세에서는 P과제가 DC과제보다 훨씬 잘 수행했으며 3세가 되면서 P과제와 DC과제 점수가 같이 높아졌다. 둘째, 연령별 과제 제시유형에 따른 NC과제 수행은 차이가 있다. 연령이 증가 할수록 과제 제시유형에서 과제의 표상 능력도 증가하였다. 연령에 따라 P과제 선행 후 NC과제와 DC과제 선행 후 NC과제의 표상의 점수는 다르다. P과제 선행 후 NC과제가 DC과제 선행 후 NC과제에서 보다 더 많은 대상의 구성요소, 쌍표상을 표현한 것으로 나타났다. 따라서, 본 연구를 통해 유아의 표상 수준의 발달은 연령과 밀접한 관계가 있고 과제에 따른 그리기 표상능력도 P과제, DC과제, NC과제 순으로 일어나며, 표상적 그리기가 1.5세와 2세경에 시작된다는 것을 보여준다.

재발성 가와사끼병의 임상양상과 검사소견

유승택,최은정,이창우,오연균,박승택,윤향석 圓光大學校 醫科學硏究所 2003 圓光醫科學 Vol.18 No.2

梓木이 腦血流 및 血壓에 미치는 影響

황경택,경은호,나한일,소응향,최병화,한종현 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1

The purpose of this study is to measure the changes of regional cerebral blood flow (rCBF) and blood pressure (BP) in rats, following the intravenous injection of Catalpa Ovata Water Extract (COWE). The measurement was continually monitored by laser-doppler flowmeter (Transonic Instrument, USA) and pressure tranducer(Grass, USA) in anesthetized adult Sprague-Dawley rats through the data acquisition system composed of MacLab and Macintosh computer. The result of this experiment was as following : COWE increased the changes of rCBF and BP significantly. After pretreatment with propranolol and indomethacin, the changes of rCBF were inhibited significantly, but not by L-NNA and methylene blue. Also, after pretreatment with propranolol, the changes of BP were inhibited significantly, but not by L-NNA, methylene blue and indomethacin. According to above result, it is considered that Catalpa Ovata increased the rCBF and BP, related to adrenergic β-receptor.

위 전절제술을 받았던 환자에서 아급성 연합성 변성 1예

한정호,하현욱,이정석,송은향,김우정,김두응,최진영 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

Subacute combined degeneration is a metabolic disorder of the spinal cord caused by vitamin B12 deficiency. A 72-year old man was admitted with weakness and tingling sensation of the bosh upper extremities. 9 years ago, he was diagnosed as having stomach cancer. So total gastrectomy with splenectomy was done at that time. The complete blood cell counts and morphology revealed megaloblastic anemia. Nerve conduction velocity study(NCV), electoromyography(EMG) and somatosensory evoked potentials(SEP) showed diffuse sensorimotor peripheral neuropathy. Magnetic resonance imaging(MRI) showed an increased T2-weighted signal, mild decreased T1-weighted signal, and slight contrast enhancement of the posterior columns of the cord in the cervical and upper thoracic spinal region. He was treated with vitamin B12 supplements and improved gradually. If abnormal sensation and muscle weakness was developed after gastrointestinal surgery, subacute combined degeneration should be considered in the differential diagnosis. We describe MRI findings of a typical case of subacute combined degeneration, which was induced by total gastrectomy.

형질전환 제초제저항성 벼 밀양 204호의 농업적 특성

정응기,이기환,원용재,박향미,전남수,최준호,구연충,한창덕,은무영,김태산,남민희 Plant molecular biology and biotechnology research 2005 Plant molecular biology and biotechnology research Vol.2005 No.

This study was conducted to investigated the major characteristics of genetically modified rice of "Milyang 204" originated from Dongjinbyeo compared to a non-transgenic rice varieties Dongjinbyeo and Junambyeo. Basta resistant transgenic rice lines carrying bar gene produced by the Yeongnam Agricultural Research Institute were evaluated for their agronomic characters. The transgenic Japonica rice of "Milyang 204" showed inferior phenotypic traits compared to a non-transgenic rice variety Dongjinbyeo and Junambyeo. On the basis of UPOV (Union Internationale Pour la Protaection des Obtentions Vegetables) and NSMO(National Seed Management Office) the transgenic "Milyang 204" showed difference in some traits out of some agronomic traits, such as leaf color, angle of flag leaf, number of spikelets, culm length, white core and white belly compared to the nontransgenic varieties rice.

원발성 연수 출혈증 1예

하현욱,한정호,이정석,송은향,김우정,김두응,최진영 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

Pure primary medullary hemorrhage is a rare condition, which is characterized by ipsilateral hypoglossal nerve palsy and contralateral hemiparesis. The hemorrhage usually extended to medial and ventral medulla, these two characteristic signs distinguished from the classical presentation of Wallenberg's lateral medullary syndrome. A 53-years-old man was admitted with sudden onset left sides weakness and vertigo. Neurologic examination showed dysarthria, mild dysphagia, Horner syndrome of right side, spontaneous horizontal jerking nystagmus to left side and right deviation of tongue at protrusion. Pain and temperature sensation of left trunk, left extremity and right face were decreased. Brain CT scan and brain MRI revealed focal hemorrhage in the right medulla. We report a case of pure primary medullary hemorrhage with undetermined etiology.

자발성 기흉을 동반한 폐림프관평활근종증 1예

안용환,정종훈,김소영,김휘정,김학렬,양세훈,최순호,문형배,조향정,정은택 圓光大學校 醫科學硏究所 2005 圓光醫科學 Vol.20 No.1