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구자웅,한강원,은종호 한국농공학회 1989 한국농공학회논문집 Vol.31 No.1
This laboratory study was performed to produce basic data for the estimation of water requirements for desalinization, through analyzing changes of the electrical conductivity and the exchangeable sodium percentage during the desalinization of reclaimed tidelands. Desalinization experiments were carried out by two water management practices, namely, the leaching method by subsurface drainage and the rinsing method by surface drainage, using samples of silt loam soil and silty clay loam soil collected in reclaimed tidelands. The results obtained from this study were summarized as follows : 1. The sample soils used in this study were saline-sodic soils with the high electrical conductivity and the high exchangeable sodium percentage. 2. Changes of the electrical conductivity and the exchangeable sodium percentage with water requirements for desalinization showed a similar tendency in the desalinization experiment by the same water management practice. 3. The regression equation between the relative electrical conductivity(EC/EC) and water requirements for desalinization(Dw/Ds) could be described by Dw/Ds=O. 29x(EC/EC.) -0.982 (Leaching method), Dw/Ds=3. 678X0. 030(EC/EC ) (Rinsing method). 4. The regression equation between the relative exchangeable sodium percentage (ESP/ESP ) and water requirements for desalinization (Dw/Ds) could be expressed in Dw/Ds = 0.039 x (ESP/ESP. ) - 1. 134 (Leaching method), Dw/Ds=7. 197X0. 024(ESP/ESP ) (Rinsing method). 5. It was estimated that water requirements for the adequate desalinization would be Dw/Ds=0.3 (Leaching method) and Dw/Ds=3.0 (Rinsing method)
재발 또는 불응성 비호즈킨 림프종 환자에서 CDME 구제항암화학요법 후 고용량 항암화학요법 및 자가말초혈액 조혈모세포이식의 효과
김세형,한강원,배상병,김찬규,이남수,이규택,박성규,원종호,홍대식,박희숙 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.1
Background and objectives : The long-term survival in patients with non-Hodgkin's lymphoma (NHL) after conventional dose chemotherapy is about 35% and the rest of the patients tend to have relapse. So, in relapsed or refractory NHL, we compared the outcome of patients undergoing high-dose chemotherapy with autologous peripheral blood stem cell transplantation(APBSCT) with only salvage chemotherapy of cisplatin, dexamethasone, mitoxantrone, and etoposide(CDME). Materials and methods : From June 1993 to December 1999, 25 patients with relapsed or resistant NHL were treated with CDME regimen as salvage chemotherapy. Twelve patients were received four cycles of CDME chemotherapy, and 13 patients were received high-dose chemotherapy with APBSCT following two cycles of CDME chemotherapy. Results : The median follow-up duration was 12.8 months(range:4-68). The overall response rate was 41.7% (complete response rate 25%, partial response rate 16.7%) in 12 patients with CDME only. Thirteen patients who were treated with high-dose chemotherapy with APBSCT achieved 61.5% complete response rate and 15.4% partial response rate, with an overall response rate of 76.9%. The estimated 3-year progression-free survival rate was significantly higher among patients who received high-dose therapy than patients who received CDME only(41.5% vs 20.0%, p<0.05). And, 3-year overall survival rate was significantly higher among patients who received high-dose therapy(51.3% vs 25.0%, p <0.05). Conclusions : In relapsed or refractory NHL, CDME chemotherapy is an effective salvage chemotherapy and allow peripheral blood stem cell collection. Also, high-dose chemotherapy with APBSCT following CDME is superior to CDME salvage chemotherapy only.