임상간호사의 뇌사자 장기기증에 대한 지식과 태도에 영향을 미치는 요인

이현아,허유진,이영규,송가람,이은지,신수진,Lee, Hyun Ah,Hur, Yujin,Lee, Young Gew,Song, Garam,Lee, Eunji,Shin, Sujin 한국중환자간호학회 2017 중환자간호학회지 Vol.10 No.3

Purpose : This study investigated factors affecting the knowledge and attitude of organ procurement from brain dead patients in nurse clinicians. Methods : A survey was conducted with 160 clinical nurses from a university hospital in Seoul. Descriptive statistics, t-tests, an ANOVA, $Scheff{\acute{e}}^{\prime}s$ test, Pearson's correlation coefficient, and a multiple regression analysis were used. Results : The mean score for knowledge of organ procurement from brain dead patients was $12.41{\pm}2.16$ (mean correct answers = 62.1). Factors influencing the knowledge of organ procurement among nurse clinicians were working department (${\beta}=.454$, p < .001), a recent family death (${\beta}=.187$, p = .014), experience recognizing potential brain dead patients (${\beta}=.182$, p = .033), and experience referring to potential brain dead patients (${\beta}=-.192$, p = .048). Conclusion : To ensure effective organ procurement from brain dead patients, it is necessary to continually educate nurse clinicians to improve their attitude and knowledge concerning organ donation.

중등도 이상의 위험 수술을 받은 환자에서 수술 전후 항혈전제 약물 사용 평가

이현아,조윤희,조윤숙,한현주,이주연,정근화,이상건,Lee, Hyeon-Ah,Jo, Yun Hee,Cho, Yoonsook,Hahn, Hyeon Joo,Lee, Ju-Yeun,Jung, Keun-Hwa,Lee, Sang Kun 한국임상약학회 2017 한국임상약학회지 Vol.27 No.1

Objective: The perioperative management of antithrombotic therapy is often challenging and it requires a fine balance between the risk of hemorrhage and thrombosis. We aimed to evaluate the antithrombotic management for moderate to high risk patients in real world setting. Methods: Among the patients who were consulted to the neurologist for the evaluation of perioperative risk from 2010 to 2012, patients undergoing moderate to high risk surgery and taking antithrombotics within 30 days were identified. We analyzed the timing of discontinuation and reinitiation of antithrombotic drugs before or after surgery as well as the status of bridging therapy. In addition, the conformity with the guideline suggested by American College of Chest Physicians was assessed. The rate of thromboembolic event and major hemorrhage were also investigated. Results: A total of 329 patients were included. The concordance rate of warfarin stop and restart time with guideline was 23.4% and 10.3%, respectively. Continuing aspirin in patients undergoing coronary artery bypass surgery or non-cardiac surgery in patients with high risk for cardiovascular events were 59.2% and 2.6%, respectively. Bridging therapy was adopted in 92.9% and 81.2% in patients who had received anticoagulant before surgery and who were at high and low risk thromboembolism, respectively. In entire cohorts, 30-day incidence of major bleeding and thromboembolic event were 31.9% and 3.0%. Co-morbid renal disease were shown as independent predictor for major bleeding (adjusted OR 2.65. 95% CI 1.33-5.28). Conclusion: The concordance rate with guideline regarding perioperative antithrombotic use was low and bridging therapy was prevalent in patients undergoing moderate to high risk surgery.

Helicobacter pylori에 대한 항균활성을 가진 천연물의 검색과 항균력 비교 연구

이현아,김옥진,Lee, Hyun-A,Kim, Okjin 대한수의학회 2013 大韓獸醫學會誌 Vol.53 No.2

Infection with Helicobacter (H.) pylori is strongly associated with duodenal and gastric ulcers. Substantial epidemiological data has revealed that high rates of H. pylori infection might be related to high rates of gastric cancer. In this study, a medicinal herbal extracts were examined and screened for anti-H. pylori activity. Seventy percent ethanol was used for herbal extraction. For anti-H. pylori activity study, the inhibitory zone tests with 74 herbal compounds were conducted. As the results, thirteen compounds including Cinnamomi Cortex, Magnoliae Cortex and Meliae Fructus were revealed strong anti-H. pylori activities.

세대별 기혼남성의 가사노동시간 연구: 베이비붐세대, X세대, Y세대를 중심으로

이현아,김주희,Lee, hyunah,Kim, Joohee 한국가족자원경영학회 2021 가족자원경영과 정책 Vol.25 No.4

The purpose of this study is to identify the influencing factors of married men's household labor time by generation to understand the changes in male participation in household labor. To this end, married men were classified into Baby Boomers, Generation X, and Generation Y, and the factors of participation in household labor for each generation were analyzed by applying the hypothesis of participation in household labor. As for the data, the original data of the National Statistical Office's "2019 Time Use Survey" were used. Multinomial logistic analysis was conducted to analyze the factors affecting married men's household labor time. As a result of the analysis, household labor time for Baby Boomers can be explained by the hypothesis of economic efficiency, gender role attitude, and the demand/response capability, while household labor time for Generation X can be explained by economic efficiency hypothesis, gender role attitude hypothesis, time-availability hypothesis, and demand/response capability hypothesis. It was found that the household labor time for Generation Y can be explained by the time-availability hypothesis and demand/response capability hypothesis. The fact that each generation has different factors of participation in household labor suggests that the characteristics of each generation should be considered in establishing policies to support the work and family balance for men.

영작문 자동 채점 시스템에서의 중복 보고 오류 제거를 통한 성능 향상

이현아,김지은,이공주,Lee, Hyun-Ah,Kim, Jee-Eun,Lee, Kong-Joo 한국정보처리학회 2009 정보처리학회논문지B Vol.16 No.2

The purpose of developing an automated scoring system for English composition is to score English writing tests and to give diagnostic feedback to the test-takers without human's efforts. The system developed through our research detects grammatical errors of a single sentence on morphological, syntactic and semantic stages, respectively, and those errors are calculated into the final score. The error detecting stages are independent from one another, which causes duplicating the identical errors with different labels at different stages. These duplicated errors become a hindering factor to calculating an accurate score. This paper presents a solution to detecting the duplicated errors and improving an accuracy in calculating the final score by eliminating one of the errors. 영어 작문 자동 채점 시스템은 수험자가 작성한 영작문을 사람의 개입 없이 시스템이 처리하여 점수나 피드백을 줄 수 있는 시스템이다. 본 논문에서 개발한 영작문 자동 채점 시스템은 단어 단계, 구문 단계, 의미 단계의 세 단계 처리 과정을 통해서 오류를 탐지하고 탐지된 오류 개수를 기반으로 채점 점수를 결정한다. 이와 같이 독립적인 세 단계의 처리 과정에서 오류를 탐지하므로 동일한 오류 현상에 대해 서로 다른 단계에서 서로 다른 이름으로 오류를 탐지하는 경우가 발생할 수 있다. 이는 결과적으로 전체 시스템의 채점 점수의 정확도를 저하시키는 원인이 된다. 본 논문에서는 동일한 오류 현상에 대해 서로 다른 단계에서 탐지된 오류 쌍을 '중복 보고 오류'라고 정의한다. 본 논문에서는 중복 보고 오류를 찾는 방법을 제안하고 중복 보고 오류 제거를 통해 영작문 자동 채점 시스템의 채점 점수를 향상시킬 수 있음을 보인다.

Helicobacter pylori에 대한 천련자 추출물의 in vitro와 in vivo 실험에서의 항균활성

이현아,김옥진,Lee, Hyun-A,Kim, Okjin 대한수의학회 2012 大韓獸醫學會誌 Vol.52 No.2

In this study, a medicinal herbal plant, Meliae fructus, was examined and screened for anti-Helicobacter (H.) pylori activity. Seventy percent ethanol was used for herbal extraction. For anti-H. pylori activity screening, inhibitory zone tests as an in vitro assay and in vivo study using a Mongolian gerbil (Meriones unguiculatus) model were performed. Also, the safety of herbal compounds was evaluated by animal study. As a result of inhibitory zone test, Meliae fructus extract demonstrated strong anti-H. pylori activities. Also, as results of in vivo animal studies, Meliae fructus demonstrated strong therapeutic effects against H. pylori infection according to the criteria of histological examination and rapid urease test. As results of the safety study, after 28 days treatment of the Meliae fructus extract, the animals were not detected any grossly and histological changes. These results demonstrate that it can be successfully cured against H. pylori infection and protected from H. pylori-induced pathology with Meliae fructus. It could be a promising native herbal treatment for patients with gastric complaints including gastric ulcer caused by H. pylori.

2차원 지리 객체를 위한 시공간 객체 모델 설계

이현아,남광우,류근호,Lee, Hyeon-Ah,Nam, Kwang-Woo,Ryu, Keun-Ho 한국정보처리학회 2002 정보처리학회논문지D Vol.9 No.1

지금까지 시공간 객체를 다양한 관점에서 접근하여 표현하려는 많은 연구가 이루어졌다. 이 대부분의 연구는 GIS적 관점과 시간 데이터베이스 관점, 그리고 객체 지향적 관점 및 데이터타입 접근 방법으로 시공간 객체를 표현하고 있다. 시공간 객체는 공간 속성이 불연속적으로 변하는 객체, 위치 정보가 연속적으로 변하는 객체, 그리고 면적과 위치가 연속적으로 변하는 객체로 분류된다. 그러나 기존의 시공간 모델들은 한 종류의 객체에만 초점을 맞추고 있다. 따라서 이 논문에서는 유클리드 평면상에서 세가지 형태의 객체를 모두 표현할 수 있는 시공간 객체 모델을 제안한다. 이를 위해 유효시간 개념을 확장한 시간 모델과 함께 객체의 연속된 두 버전간의 관계성을 정의하여 이동 객체와 이력 객체 모두를 표현하는 방식을 사용한다. 여기서 제안하는 2차원 시공간 객체 모델은 개방형 GIS 명세서에서 제시하고 있는 2차원 공간 객체 모델을 따름으로써 표준 공간 모델과의 호환성을 보장한다. Most of works have been performed on representation of spatiotemporal objects from various points of view. Most of them represent spatiotemporal objects using approaches from GIS, temporal databases, object-oriented databases or data type. Spatiotemporal objects can be classified as objects whose position and shape changes discretely over time, objects whose position changes continuously and objects whose shape changes continuously as well as position. Previous works on spatiotemporal model have focused on only one of them. In this paper, we propose a spatiotemporal model that can represent three types of objects in Euclidean plan. For this purpose, we represent both discrete and continuous moving objects by defining temporal model extended from valid time and by defining relationship between two consecutive versions of objects. The proposed spatiotemporal object model is based on open GIS specification so that it has compatibility with existing spatial data model.

Effects of cold stress as a pathogenic factor on fatal disease progression of canine herpesvirus

이현아,홍선화,이윤성,김동우,권혜영,Cheol-Yong Lee,김옥진 충북대학교 동물의학연구소 2014 Journal of Biomedical and Translational Research Vol.15 No.3

Canine herpesvirus (CHV) is a member of the alphaher- pesvirus subfamily, which can cause severe hemorrhagic diseases in neonatal pups as well as mild or subclinical respi- ratory infections in adult dogs. We examined the effects of cold stress on disease progression of CHV, an alphaherpes- virus, in neonatal puppies. Eight puppies were challenged intranasally with CHV suspension and divided into a cold stress treatment group and a hyperthermal group. Four pups were left uninoculated as controls and divided into cold and hyperthermal groups. In the challenged cold treatment group, all pups showed CHV-related disease within 5 days; pathological changes were observed in organs of puppies showing clinical symptoms. Grossly, numerous petechial red foci were scattered throughout lungs, kidneys, livers, and intestines of all CHV-infected puppies exposed to cold stress. Most puppies showed typical clinical signs and macroscopic lesions, and CHV infection was confirmed by isolation of the virus. However, in the challenged hyperthermal group, only one of the pups showed mild symptoms of CHV-induced disease. None of the puppies in the uninoculated group showed abnormal signs, although they were exposed to cold stress. These findings indicate that cold stress can cause rapid disease progression of CHV, an alphaherpesvirus.

충격과 마모를 고려한 원자로 핵연료봉 지지격자의 설계

이현아,김종기,송기남,박경진,Lee, Hyun-Ah,Kim, Chong-Ki,Song, Kee-Nam,Park, Gyung-Jin 대한기계학회 2007 大韓機械學會論文集A Vol.31 No.10

The spacer grid set is a component in the nuclear fuel assembly. The set supports the fuel rods safely. Therefore, the spacer grid set should have sufficient strength for the external impact forces such as earthquake. The fretting wear occurs between the spring of the fuel rod and the spacer grid due to flow-induced vibration. Conceptual design of the spacer grid set is performed based on the Independence Axiom of axiomatic design. Two functional requirements are defined for the impact load and the fretting wear, and corresponding design parameters are selected. The overall flow of design is defined according to the application of axiomatic design. Design for the impact load is carried out by using nonlinear dynamic analysis to determine the length of the dimple. Topology optimization is carried out to determine a new configuration of the spring. The fretting wear is reduced by shape optimization using the homology theory. The deformation of a structure is called homologous if a given geometrical relationship holds before, during, and after the deformation. In the design to reduce the fretting wear, the deformed shape of the spring should be the same as that of the fuel rod. This condition is transformed to a function and considered as a constraint in the shape optimization process. The fretting wear is expected to be reduced due to the homology constraint. The objective function is minimizing the maximum stress to allow a slight plastic deformation. Shape optimization results are confirmed through nonlinear static analysis.

지하수 모니터링을 통한 지진 감시 가능성: 중규모(M4.9) 오대산 지진의 관측

이현아,김민형,홍태경,우남칠,Lee, Hyun-A,Kim, Min-Hyung,Hong, Tae-Kyung,Woo, Nam-C. 한국지하수토양환경학회 2011 지하수토양환경 Vol.16 No.3

Groundwater monitoring data from the National Groundwater Monitoring Stations, a total of 320 stations, were analyzed to identify the response of water level and quality to the Odaesan earthquake (M4.9) occurred in January 2007. Among the total of eight stations responded to the earthquake, five wells showed water-level decline, and in three wells, water level rose. In terms of recovery, water levels in four stations had recovered to the original level in five days, but not in the rest four wells. The magnitude of water-level change shows weak relations to the distance between the earthquake epicenter and the groundwater monitoring station. However, the relations to the transmissivities of monitored aquifer in the station with the groundwater change were not significant. To implement the earthquake monitoring system through the groundwater monitoring network, we still need to accumulate the long-term monitoring data and geostatistically analyze those with hydrogeological and tectonic factors.