중풍환자(中風患者)의 불면증(不眠症)에 피내침(皮內針)의 유효성(有效性) 및 적응증(適應證) 평가(評價)

이상호,김은주,김이동,윤상필,이차로,홍진우,정동원,문상관,조기호,김영석,Lee Sang-Ho,Kim Eun-Ju,Kim Lee-Dong,Yun Sang-Pil,Lee Cha-Ro,Hong Jin-Woo,Jeong Dong-Won,Moon Sang-Kwan,Cho Ki-Ho,Kim Young-Suk 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.1

Objective : Insomnia is the disorder of initiation or maintenance in sleeping that results in daytime sleepiness and dysfunction, and it arises from multiple psychological, physiological and environmental factors. A number of stroke patients suffer from insomnia are classified as sleep disorder patients with physical illness. In addition, insomnia may have profound deleterious effects on the natural course of stroke. We are to assess the effectiveness of intradermal acupucture on stroke combined with insomnia. Methods : We recruited hospitalized patients with insomnia after stroke. Then, the subjects were allocated into a treatment group and a control group by randomization. The treatment group received intradermal acupuncture therapy at He-7(神門), EH-6(內關) correctly. However in control group, intradermal acupuncture were just attached to He-7(神門), EH-6(內關) without insertion. Treatment over time at first day and second day a various indexes were repeatedly checked such as sleep latency, total sleep time, sleep quality, condition on awakening, ability of concentration, morning sleepiness, Insomnia Severity Index, and Athens Insomnia Scale. In the second analysis, we divided the treatment group into a response and a non-response group by their response to intradermal acupuncture. With the acupuncture treatment, accompanied symptoms were checked Results : Among thirty two subjects, two of them were dropped out: One complained the pain from needle insertion, and the other underwent the change of his herbal medication. At baseline investigation with the residual 30 subjects, the control and the treatment group were assessed to have an equal comparability. In the treatment group, sleep latency, total sleeping time, a number of awakenings, sleep quality and ability of concentration showed improvement significantly compared with the control group. The non-response Group showed symptoms such as nausea and halitosis, belching and acid regurgitation, abundant expectoration, while Responder Group showed palpitation, oppressed feelings in chest and sleep disorder. Conclusions: The result of this clinical study suggests that the intradermal acupuncture at He-7(神門), EH-6(內關) is one of the effective treatments for the insomnia after stroke.

반도체 습식 세정 공정 중 상온의 초순수와 염기성 수용액 내에서 오존의 용해도 최적화

이상호,이승호,김규채,권태영,박진구,배소익,이건호,김인정,Lee Sang-Ho,Lee Seung-Ho,Kim Kyu-Chae,Kwon Tae-Young,Park Jin-Goo,Bae So-Ik,Lee Gun-Ho,Kim In-Jung 한국반도체디스플레이기술학회 2005 반도체디스플레이기술학회지 Vol.4 No.4

The process optimization of ozone concentration and half life time was investigated in ultra pure water and alkaline solutions for the wet cleaning of silicon wafer surface at room temperature. In the ultra pure water,. the maximum concentration (35 ppm) of ozone was measured at oxygen flow rate of 3 liters/min and ozone generator power over 60%. The half life time of ozone increased at lower power of ozone generator. Additive gases such as $N_2$ and $CO_2$ were added to increase the concentration and half life time of ozone. Although the maximum ozone concentration was higher with the addition of $N_2$ gas, a longer half life time was observed with the addition of $CO_2$. When $NH_4OH$ of 0.05 or 0.10 vol% was added in DI water, the pH of the solution was around 10. The addition of ozone resulted in the half life time less than 1 min. In order to maintain high pH and ozone concentration, ozone was continuously supplied in 0.05 vol% ammonia solutions. 3 ppm of ozone was dissolved in ammonia solutions. The static contact angle of silicon wafer surface became hydrophilic. The particle removal was possible alkaline ozone solutions. The organic contamination can be removed by ozonated ultra pure water and then alkaline solution containing ozone can remove the particles on silicon surface at room temperature.

PREVENTIVE EFFECT OF ADHESIVE TAPE SUPPLEMENTED WITH NaF ON ENAMEL EROSION IN VITRO

이상호,이난영,이인화,Lee, Sang-Ho,Lee, Nan-Young,Lee, In-Hwa Korean Academy of Pediatric Dentistry 2010 大韓小兒齒科學會誌 Vol.37 No.1

본 연구는 불소함유 접착테잎의 법랑질 침식 예방효과를 평가하기 위해건강한 소의 치아를 절단하여 아크릴 주형에 매몰하고 정중선에 홈을 형성하여 대조면과 불소 제제를 도포할 실혐면으로 나누었다. 시편을 무작위로 18개씩 4군으로 나누었다. 1군은 APF gel를 도포하고, 2군은 불소 바니쉬를 도포하였으며, 3군과 4군은 5% NaF를 각각 첨가한 methyl cellulose와 poly vinyl alcohol 테잎을 부착하였다. 시편을 콜라에 5분, 증류수에 10분씩 6회 번갈아 처리하며 5일 동안 반복하였다. 시간 경과에 따라 표면미세경도를 측정하고 5일후 각 시편을 절단하여 침식병소의 깊이를 측정하여 다음과 같은 결과를 얻었다. 1. 표면미세경도 값은 5일째만 제외하고 2군, 3군, 4군의 실험면이 각각의 대조면에 비해 컸다 (p<0.05). 2군, 3군, 4군의 실험면 역시 5일째만 제외하고 1군의 실험면에 비해 표면미세경도가 컸다 (p<0.05). 3군과 4군 사이에는 표면미세 경도의 유의한 차이가 없었다(p>0.05). 1군의 실험면과 대조면은 표면미세경도의 유의차가 없었다(p>0.05). 2. 침식병소의 깊이는 2군, 3군, 4군의 실험면이 각각의 대조면에 비해 컸다(p<0.05). 2군, 3군, 4군의 실험면은 1군의 실험면에 비해 침식병소의 깊이가 얕았다 (p<0.05). 2군, 3군, 4군의 실험면 사이의 침식병소의 깊이는 유의차가 없었다(p>0.05). 상기 결과로 보아 새로 개발된 불소함유 접착테잎은 기존의 불소 바니쉬와 같은 법랑질 침식 예방효과가 분명하게 나타나, 법랑질 침식에 감수성이 높은 어린이 환자에게 임상적인 예방법으로서 활용할 수 있는 가능성이 높다고 사료된다. This study examined the effect of adhesive tape supplemented with sodium fluoride on the prevention of dental erosion in vitro. Sound bovine tooth samples were selected and divided randomly into the following 4 groups according to the material treatments: group 1, APF gel; group 2, fluoride varnish; and groups 3 and 4, fluoride tape supplemented with 5% NaF in either a methyl cellulose or poly vinyl acetate carrier, respectively. All specimens were submitted to alternate cycles of acid exposure in a cola beverage (pH 4.3) and artificial saliva for $6\;{\times}\;5\;min/day$ over a 5 day period. The micro-hardness was recorded each day and the lesion depth was measured after 5 days. The micro-hardness of the experimental sides of groups 2, 3 and 4 were significantly higher than that of their control sides and the experimental side of group 1 during the experimental period (p<0.05) except on the 5th day. The enamel surfaces of treatment groups 2, 3 and 4 showed significantly higher resistance to mineral loss in terms of the erosion depth (p<0.05) than group 1 and their control sides. There was no statistically significant difference among group 2, 3 and 4, indicating that the fluoride varnish and tapes produce similar results. Fluoride adhesive tapes are effective in reducing the progression of erosion and can be recommended for young patients who are more susceptible to dental erosion.

이어도 종합해양과학기지의 복사관측소 환경 개선 및 국제화 추진 전략

이상호,조일성,이규태,김부요,정현석,임세훈,변도성,이주영,LEE, SANG-HO,Zo, Il-SUNG,LEE, KYU-TAE,KIM, BU-YO,JUNG, HYUN-SEOK,RIM, SE-HUN,BYUN, DO-SEONG,LEE, JU-YEONG 한국해양학회 2017 바다 Vol.22 No.3

정확한 복사 관측자료는 기후 및 날씨뿐만 아니라 해양과 건축 및 농 축산 분야 등 중요하게 활용된다. 특히 이어도와 같은 종합 해양과학기지는 주변 환경에 의한 복사 반사 효과를 최소화할 수 있기 때문에 이상적인 관측소로 평가되며 여기서 생산되는 자료는 복사관측의 기준 자료가 될 수 있다. 또한 BSRN (Baseline Surface Radiation Network) 등 세계복사관측그룹 가입을 위한 필수 장비들(전천과 직달 및 산란 일사계 등)을 갖추고 관측소 환경을 개선할 경우 전 세계적인 중요 관측소로 부각될 수 있는 여건을 갖추고 있다. 이어도 종합해양과학기지는 2004년 11월부터 일사계 관측을 수행해 왔고 이 연구에서는 2005년 1월 1일부터 2015년 12월 31일까지의 자료를 분석하였다. 이 연구 기간에 이어도의 일평균 일사량은 $-3.80W/m^2/year$로 감소하였고 그 이유는 자연적 원인 이외에 관측장비의 센서 반응도 감소 효과가 포함되어 있기 때문이다. 즉 이어도 종합해양과학기지의 경우 정밀한 복사 관측 자료를 생산하기 위해서는 관측소 환경 개선뿐만 아니라 관측장비 및 자료 보정이 요구된다. 그리고 한반도의 대기 청정도와 국민 건강을 크게 위협하고 있는 중국발 황사와 미세 먼지는 전 세계 과학자들의 중요 관심 대상이기 때문에 이어도뿐만 아니라 신안 가거초 및 옹진 소청초 종합해양과학기지 복사 관측자료를 통한 공동 대응 근거 마련이 필요하며 그에 따라 이들 복사관측소 환경 및 장비 개선 그리고 관측자료 정확성 향상 계획 수립이 시급하다. The radiation observation data will be used importantly in research field such as climatology, weather, architecture, agro-livestock and marine science. The Ieodo Ocean Research Station (IORS) is regarded as an ideal observatory because its location can minimize the solar radiation reflection from the surrounding background and also the data produced here can serve as a reference data for radiation observation. This station has the potential to emerge as a significant observatory and join a global radiation observation group such as the Baseline Surface Radiation Network (BSRN), if the surrounding of observatory is improved and be equipped with the essential radiation measuring instruments (pyaranometer and pyrheliometer). IORS has observed the solar radiation using a pyranometer since November 2004 and the data from January 1, 2005 to December 31, 2015 were analyzed in this study. During the period of this study, the daily mean solar radiation observed from IORS decreased to $-3.80W/m^2/year$ due to the variation of the sensor response in addition to the natural environment. Since the yellow sand and fine dust from China are of great interest to scientists around the world, it is necessary to establish a basis of global joint response through the radiation data obtained at the Ieodo as well as at Sinan Gageocho and Ongjin Socheongcho Ocean Research Station. So it is an urgent need to improve the observatory surrounding and the accuracy of the observed data.

경북지역 친환경딸기 농가의 인증유형에 따른 효율성 분석

이상호,송경환,Lee, Sang-Ho,Song, Kyung-Hwan 한국유기농업학회 2013 韓國有機農業學會誌 Vol.21 No.4

The purpose of this study is to estimate efficiency of environmental-friendly agricultural product by using Data Envelopment Analysis. A proposed method employs a bootstrapping approach to generating efficiency estimates through Monte Carlo simulation resampling process. The technical efficiency, pure technical efficiency, and scale efficiency measure of strawberry by pesticide-free certification is 0.967, 0.995, 0.968 respectively. However those of bias-corrected estimates are 0.918, 0.983, 0.934. We know that the DEA estimator is an upward biased estimator. In technical efficiency, average lower and upper confidence bounds of 0.807 and 0.960. According to these results, the DEA bootstrapping model used here provides bias-corrected and confidence intervals for the point estimates, it is more preferable.

LPS로 유도된 마우스 대식세포주인 RAW264.7에서 MAPK 조절에 의한 백미 물추출물의 항염증 활성

이상호,유지현,길기정,Lee, Sang-Ho,Yoo, Ji-Hyun,Kil, Ki-Jung 대한본초학회 2022 大韓本草學會誌 Vol.37 No.6

Objectives : To develop natural ingredients that help prevent or treat anti-inflammatory-related diseases and use themas basic data, we investigated anti-inflammatory activity of Cynanchi Atrati Radix Et Rhizoma water extracts(CWE) in lipopolysaccharide(LPS)-induced murine macrophage cell line, RAW 264.7 cells. Methods : The cell viabilities were evaluated with RAW 264.7 cells. The production of nitric oxide(NO), prostaglandin E2(PGE2), pro-inflammatory cytokines such tumor necrotic factor(TNF)-α and interleukin(IL)-6 were assessed in LPS-induced RAW 264.7 cell treated with CWE. Furthermore, the protein expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2(COX-2), and mitogen-activated protein kinase(MAPK) were assessed by western blotting. Results : In RAW 264.7 cell, the cell viability by CWE treatment was more than 98.4% at a concentration of 100-400 ㎍/mL. At a concentration of 800 ug/ml of CWE, the cell viability was as low as 86%. At doses of 100, 200 and 400 ㎍/mL, CWE inhibited the production of NO, PGE2, TNF-𝛼 and IL-6 in a dose-dependent manner and also decreased the expression of iNOS and COX-2 from LPS-induced RAW 264.7 cells. In addition, CWE significantly inhibited the MAPK pathway including decreased the phosphorylation of the p38, c-Jun N-terminal kinase(JNK) and extracellular signal-regulated kinase(ERK1/2). Conclusions : Our study provides evidence that CWE inhibits the production of main pro-inflammatory molecules in LPS-induced RAW 264.7 cells via expression of p38, JNK, and ERK1/2 MAPK signaling pathways. Therefore, CWE is expected to be widely used as a natural ingredient for anti-inflammatory functional foods or pharmaceuticals in the future.

CAD Allegro을 이용한 환경 자동실행으로 PCB작업시간 단축에 대한 연구

이상호,김영길,Lee, Sang-Ho,Kim, Young-Gil 한국정보통신학회 2012 한국정보통신학회논문지 Vol.16 No.6

휴대폰 및 카메라 산업의 급속한 발전에 따라 모든 전자 제품이 소형화, 고성능화, 다양화 추세에 따라 PCB도 고집적화, 다층화, 고사양화가 급속히 이루어지고 있다. 현재 계속해서 진화하고 발전하는 디지털 카메라 그 중에서도 DSLR카메라 이외에 소형, 경량화 하는 고객 요구로 부터 탄생한 미러리스 카메라와 하이브리드 디지털 카메라의 시장이 계속해서 증가하고 있다. 그에 고사양, 저전력, 고성능 부품에 따라 PCB설계 난이도가 점차 증가하고 설계 L/T이 오래 걸리고 있다. 본 논문에서는 디지털 카메라 개발기간 및 제조기간 축소에 적용되는 PCB설계 L/T 단축에 대한 방법을 제안한다. According to the rapid development of cell phone and camera industry, all of electronic products obtain small-size, high-performance and variety. Therefore, PCB also obtains high-integration, multi-layers and high-specification rapidly. Among the digital cameras which are continuously evolved and developed, the market of mirror-less camera and hybrid digital camera is continuously increased because of the customer's request for small-size and weight lightening, except for DSLR camera. Therefore, the difficulty of PCB design is gradually increased and design L/T is longer according to the high-specifications, low-current and high-performance components. This thesis suggests the method to reduce L/T for PCB design applied to the reduction of digital camera's developing period and manufacturing period.

인공신경망을 이용한 퇴적암의 압축강도 예측

이상호,김동락,서인식,Lee, Sang-Ho,Kim, Dong-Rak,Seo, In-Shik 한국농공학회 2012 한국농공학회논문집 Vol.54 No.5

A evaluation for the strength of rock includes a lot of uncertainty due to existence of discontinuity surface and weakness plain in the rock mass, so essential test results and other data for the resonable strength analysis are absolutely insufficient. Therefore, a analytical technique to reduce such uncertainty can be required. A probabilistic analysis technique has mainly to make up for the uncertainty to investigate the strength of rock mass. Recently, a artificial neural networks, as a more newly analysis method to solve several problems in the existing analysis methodology, trends to apply to study on the rock strength. In this study the unconfined compressive strength from basic physical property values of sedimentary rock, black shale and red shale, distributed in Daegu metropolitan area is estimated, using the artificial neural networks. And the applicability of the analysis method is investigated. From the results, it is confirmed that the unconfined compressive strength of the sedimentary rock can be easily and efficiently predicted by the analysis technique with the artificial neural networks.

요통 유무에 따른 경항통 환자의 경추 전만각 퇴행성 변화 비교분석

이상호,정석희,이종수,김성수,신현대,Lee, Sang-Ho,Chung, Seok-Hee,Lee, Jong-Soo,Kim, Sung-Soo,Shin, Hyun-Dae 척추신경추나의학회 2001 대한추나의학회지 Vol.2 No.1

Objectives : To study the cervical lordosis and disc degeneration in neck pain patients with or without low back pain. Subjects. The study was composed of 57 neck pain patients with low back pain(LBP group) and 40 neck pain patients without low back pain(Non-LBP group). Methods : Radiographic measures of spinal lordosis(cervical and lumbar) and disc degeneration were collected, and statistically analyzed. Results: LBP group showed a significant increase in cervical lordotic angle as compared with Non-LBP group, whereas no significant change in cervical disc degeneration. A relationship was found between cervical and lumbar disc degeneration in LBP $group({\gamma}-0.3064)$. Conclusions : The findings from this study suggest that the curvature of the cervical spine is related to the subject's low back pain.

"창립 20주년을 맞이 하면서···"

이상호,Lee, Sang-Ho 한국환경기술인연합회 2006 환경기술인 Vol.23 No.3