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Risk Assessment for Heavy Metals in Korean Foods and Livestock Foodstuffs
권영민,이경희,이행신,박선오,박정민,김진만,강경모,노기미,김동술,이종옥,홍무기,최달웅,Kwon, Young-Min,Lee, Kyoung-Hee,Lee, Haeng-Shin,Park, Seon-Oh,Park, Jung-Min,Kim, Jin-Man,Kang, Kyung-Mo,No, Ki-Mi,Kim, Dong-Sul,Lee, Jong-Ok,Hong, Moo- Korean Society for Food Science of Animal Resource 2008 한국축산식품학회지 Vol.28 No.3
This study was conducted to evaluate exposure level and risk of heavy metals in livestock foodstuffs and Korean foods. Based on the "Food Intake Data," a part of the 2005 National Health & Nutrition Survey and the "2005 Seasonal Nutrition Survey", 113 Korean foods items were selected. 3 samples from different manufacturers of each 113 items of Korean foods were purchased on summer and fall, so total 678 samples were used. The food groups were classified into 15 categories. For the livestock foodstuffs category, meats and poultry (chicken, pork, pork belly, beef, beef feet soup), milks and dairy products (milk, ice cream, liquid yoghourt, sherbet), eggs (egg) were selected. It was found that the daily amount of heavy metals intake (mg/person/day) from livestock foodstuffs is 0.00020 arsenic, 0.00000 cadmium, 0.00020 lead, and 0.00006 mercury, and the daily amount of heavy metals intake (mg/person/day) from Korean foods is 0.0265 arsenic, 0.0083 cadmium, 0.0067 lead, and 0.0028 mercury. Daily amount of heavy metals intake from livestock foodstuffs was low among the food groups. For risk assessment, PDI (Probable Daily Intake) was calculated and compared with PTWI (Provisional Tolerable Weekly Intake) of JECFA (Joint FAO/WHO Expert Committee on Food Additive). Relative hazard of these livestock foodstuffs was 0.006% in arsenic, 0.000% in cadmium, 0.085% in lead, and 0.149% in mercury. Relative hazard of Korean foods was 0.941% in arsenic, 14.676% in cadmium, 3.319% in lead, and 6.860% in mercury. Thus, livestock foodstuffs and Korean foods were as safe as satisfied with the recommended standards of JECFA.
Evaluation of Acute oral and Dermal Toxicity of Pectinase Lyase-modified Red Ginseng (GS-E3D)
Mi Kyung Pyo(표미경),Gyeong Hee Lee(이경희),Jin Seong Kim(김진성),Yun Ho Jo(조윤호),You Jin Lee(이유진),Dayu Jung(정다유),Dae Seok Yoo(유대석),Won Yong Kim(김원용),Seon Woo Cha(차선우),Ki Young Park(박기용),Ki Moo Lee(이기무) 한국약용작물학회 2018 한국약용작물학회 학술대회논문집 Vol.2018 No.2
Skin Safety Evaluation of Pectinase Lyase-modified Red Ginseng (GS-E3D) in Human Patch Test
Mi Kyung Pyo(표미경),Gyeong Hee Lee(이경희),Jin Seong Kim(김진성),Yun Ho Jo(조윤호),You Jin Lee(이유진),Dayu Jung(정다유),Dae Seok Yoo(유대석),Won Yong Kim(김원용),Seon Woo Cha(차선우),Ki Young Park(박기용),Ki Moo Lee(이기무) 한국약용작물학회 2018 한국약용작물학회 학술대회논문집 Vol.2018 No.2
한은정,박금주,최윤숙,한기철,박종석,이경희,고성권,정성현,Han, Eun-Jung,Park, Keum-Ju,Choi, Yun-Sook,Han, Ki-Chul,Park, Jong-Suk,Lee, Kyung-Hee,Ko, Sung-Kwon,Chung, Sung-Hyun 대한약학회 2006 약학회지 Vol.50 No.5
Type 2 diabetes mellitus is a chronic and hard to control disease. In order to develop the therapeutic agent for type 2 DM, many researchers investigated natural products using an in vitro and in vivo assay. In this study, we tried to explore the anti-diabetic activity and mechanisms of ginsam, which is a vinegar-processed ginseng radix. The db/db mice were randomly divided into four groups. The diabetes control (DC) group was orally administrated with distilled water, ginseng radix (GR) or ginsam (GS) was administrated orally at a dose of 150 mg/kg, and the positive control group was orally injected with metformin (MET) at a dose of 300 mg/kg for 5 weeks in db/db mice and measured body weight and blood glucose level every week. All treatment groups decreased the plasma glucose levels compared with diabetic control and GS group significantly lowered the insulin resistance index. GS group also reduced the plasma lipid levels mainly due to reduce the lipogenesis and increase the lipolysis in the fat tissue. In addition, GS group increased the GLUT4 mRNA expression levels in the fat and muscle tissues by 10 fold probably due to increase a $PPAR_{-\gamma}$ mRNA expression in fat tissue. Taken together, GS showed the anti-hyperglycemic and anti-hyperlipidemic activities and those activities may ascribe to over-expression of GLUT4 mRNA level and decrease the lipogenesis in fat tissue.
GNP법에 의해 합성한 (La<sub>1-x</sub>Sr<sub>x</sub>)Mn<sub>1+y</sub>O<sub>3−δ</sub> 분말의 출발물질에 따른 특성
이미재,김세기,지미정,최병현,박상선,이경희,Lee, Mi-Jai,Kim, Sei-Ki,Jee, Mi-Jung,Choi, Byung-Hyun,Park, Sang-Sun,Lee, Kyung-Hee 한국세라믹학회 2007 한국세라믹학회지 Vol.44 No.1
We synthesized $(La_{1-x}Sr_x)MnO_3$ as a cathode for SOFC by glycine nitrate process (GNP) and knew the different properties of $(La_{1-x}Sr_x)MnO_3$ by using nitrate solution and oxide solution as a starting material. In case of using nitrate solution as a starting material, main crystal phase peak of $LaMnO_3$ increased as Sr content added up and a peak of $Sr_2MnO_4\;and\;La_2O_3$ was showed as a secondary phase. We added Mn excess to control a crystal phase. In this case, the electrical conductivity had a high value 210.3 S/cm at $700^{\circ}C$. On the other side, when we used oxide solution as a starting material, we found main crystal phase of $LaMnO_3$ to increase as Sr content added up and a peak of $La_2O_3$ as a secondary phase. Similary, we added Mn excess to control a crystal phase in this case. We knew $(La,Sr)MnO_3$ powder to sinter well and the electrical conductivity of the sintered body at $1200^{\circ}C$ for 4 h was 152.7 S/cm at $700^{\circ}C$. The sintered $(La,Sr)MnO_3$ powder at $1000^{\circ}C$ for 4 h got the deoxidization peak, depending on the temperature and in case of using nitrate solution as a starting material, the deoxidization peak was showed at $450^{\circ}C$ which is lower than used a oxide solution as a starting material. As a result, when $(La,Sr)MnO_3$ powder was synthesized to add Mn excess and to use nitrate solution as a starting material, we found it to have the higher deoxidization property and considered it as a cathode for SOFC properly. And we found it to have different electrical conductivity the synthesized $(La,Sr)MnO_3$ powder by using different starting materials like nitrate solution and oxide solution which influence a sintering density and crystal phase.