그래프 마이닝에서 유사탐색공간을 이용한 빈도수계산 회피

노영상, 유은일, 김명준 충북대학교 컴퓨터 정보통신 연구소 2009 컴퓨터정보통신연구 Vol.17 No.2

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급성기 노인전문병동에 입원한 노인성 질환 환자에서 관찰되는 빈혈의 임상적 의의

김은일 ( Eun Il Kim ),서예원 ( Ye Won Suh ),정수현 ( Su Hyun Jung ),김은영 ( Eun Young Kim ),김혜영 ( Hye Young Kim ),박명숙 ( Myung Sook Park ),유기동 ( Ki Dong Yu ),김광일 ( Kwang Il Kim ),김철호 ( Cheol Ho Kim ) 대한내과학회 2007 대한내과학회지 Vol.72 No.1

목적: 노인 환자에서 흔히 관찰되는 빈혈과 노인의 신체적인 기능, 정서적인 기능, 영양상태와의 상관관계를 알아보고 빈혈의 동반 유무가 급성 질환으로 입원한 노인 환자의 예후에 영향을 미치는 가를 알아보고자 본 연구를 수행하였다. 방법: 2004년 5월부터 2005년 4월까지 분당 서울대학교 병원 급성기 노인전문 병동에 입원한 431명의 환자 중 의학적 평가, 기능평가, 영양상태평가, 인지기능평가, 정서상태 평가 등을 포함한 노인 포괄평가가 가능한 환자 308명을 대상으로 입원 당시 혈색소치와 포괄적 노인평가 항목과의 통계적 분석을 시행하였으며 환자의 입원 기간 및 입원 기간 중의 노인 증후군의 발생 빈도를 비교하였다. 결과: 빈혈군이 정상군에 비해 보다 고령이고 남성이 많았으며 영양 결핍과 기능 의존 상태인 특성을 관찰할 수 있었다. 이러한 특성으로 인해 빈혈군에서 입원기간 중 섬망의 발생이 보다 많았고 입원 기간의 유의한 연장이 관찰되었다. 그러나 입원 기간에 영향 미치는 여러 인자 중 빈혈이 독립적인 위험 인자인지를 알아보기 위한 다변량 분석에서 유의한 상관관계는 없었다. 결론: 빈혈은 신체적인 기능, 영양 상태와 밀접한 상관관계가 있으며 전반적인 환자의 상태를 반영해 주는 지표로 생각되나 그 자체가 독립적으로 환자의 입원 기간을 연장시키는 위험인자는 아닐 것으로 생각된다. 향후 노인 환자에서 빈혈의 임상적 의의와 그 치료적 접근에 관해서는 추가적인 임상연구가 수행되어야 할 것으로 생각된다. Background: Anemia is a common medical problem among the elderly; it is more frequent with advancing age. Anemia has been associated with adverse outcomes such as hospitalization, disability and mortality. However, the clinical significance of anemia in frail elderly patients, especially those admitted to acute care units, has not been investigated. Methods: From May 2004 to April 2005, 308 patients 65 years of age or older, admitted to the Acute Elderly Care Unit at the Seoul National University Bundang hospital, were enrolled in the current study. Comprehensive geriatric assessment including medical, psychosocial and functional evaluation was performed by the geriatric team. Clinical and laboratory evaluations were carried out to determine the prevalence and etiology of the anemia. Results: Anemia (Hb < 13 g/dL in male, < 12 g/dL in female) was identified in 149 patients (48.4%). The leading cause of anemia was anemia of chronic disease (N=75, 50.3%). Comparison between the anemic group and a control group was performed. Anemic patients were older, male, had an impaired functional status as well as a poor nutritional status. Moreover, the development of delirium was more frequent in the anemic group compared to the control group (11.0% vs 20.7%, p=0.021). In addition, the duration of hospitalization was significantly increased in patients with anemia (12.97±1.24 vs 18.07±1.77, p=0.019). However, in the multiple regression analysis, the presence of anemia did not affect the length of hospitalization as an independent factor. Conclusions: Anemia is common in frail elderly patients and has been associated with a poor clinical outcome. Although anemia was not an independent risk factor in the elderly patients, the anemia was associated with multiple co-morbidities, disability and frailty. Therefore, the presence of anemia in the elderly requires active investigation and management. (Korean J Med 72:44-51, 2007)

급성기 노인전문병동에 입원한 노인성 질환 환자에서 관찰되는 빈혈의 임상적 의의

김은일,유기동,서예원,정수현,김은영,김혜영,박명숙,김광일,김철호 대한내과학회 2005 대한내과학회 추계학술대회 Vol.2005 No.1

尿中 鉛 및 蛋白質 排泄量의 補正方法에 關한 實驗的 硏究

兪炳龍,廉容泰,李恩一 고려대학교 의과대학 1994 고려대 의대 잡지 Vol.31 No.1

One of the most important issue in occupational health is to estimate the exposure status or health effects of workers by hazardous chemicals through biological monitoring. The one of the most commonly used tests in biological monitoring to assess the internal doseof a chemical is the measurement of a metabolite or sometimes of the chemical itself in urine. Results from a 24-hour specimen is most representative of average body burden, but it is more difficult to obtain, so it is impractical and more likely to be contaminated. Therefore the analyses are commonly performed on "spot" specimens, and it is necessary to correct the results for the dilution of the urine in order to obtain a reliable estimation by adjustment methods. The most commonly used methods are the specific gravity method and the creatinine method. But these adjustment methods are not reliable satisfactorily, and some other adjustment methods have been suggested by some researchers. This study had been done to develop more reliable adjustment methods of protein and lead measurement in spot urine, and to seek the factors which affect the variability of spot urine. The subjects were 10 workers who had been exposed to lead above TLV. The results were as follows : 1. The coefficients of variation of lead in urine were greater than those of protein both in 21 hour urine specimen and in spot urine specimen. And in the results in spot urine specimens, the coefficients of variation of adjusted concentrations were less than that of unadjusted concentrations of both the protein and lead. 2. The correlation coefficients of urinary lead(adjusted concentration and unadjusted concentration) between in spot urine specimen and in 24-hour urine specimen were 0.6-0.8, and those of creatinine adjusted value between in spot urine specimen and in 24-hour urine specimen were lower in workers who had high level of blood lead(<40㎍/dl) than in workers who had low level of blood lead(>40㎍/dl). 3. The correlation coefficients of urinary protein(adjusted concentrations and unadjusted concentration) between in spot 'urine specimen and in 24-hour urine specimen were 0.6-0.8, and those of creatinine adjusted value between in spot urine specimen and in 24-hour urine specimen were lower in workers who had high level of blood lead(>40㎍/dl) than in workers who had low level of blood lead(<40㎍/dl). 4. The spot urine concentrations adjusted by log-creatinine both of protein and lead were correlated highest to 24 hour urine concentrations in all three adjustment methods such as creatinine adjustment, log-creatinine adjustment and specific gravity adjustment method. 5. The important factors which affect the variation of spot urine were specific gravity in urinary lead, and specific gravity and urinary volume or blood lead and specific gravity in urinary protein. 6. Urinary lead concentrations was not affected seriously by urinary creatinine and urinary volume, but urinary protein concentration was affected largely by urinary creatinine, specific gravity and urinary volume. The urinary protein adjusted by specific gravity was less affected than other adjustment methods. 7. The recommended adjustment method for urinary lead and protein in worker exposed to lead above TLV is log-creatinine method and specific gravity method.

지표 투과 레이더 탐사 데이터 구축과 인공지능 기반 지하 공동 탐지에 대한 연구

정다혜(Dahye Jeong),유혜림(Hyerim Yu),차준엽(Junyeop Cha),김서윤(Seoyun Kim),안형진(Hyeongjin Ahn),지염염(Yanyan Chi),이기석(Giseok Lee),노명근(Myounggun Noh),박은일(Eunil Park) 한국정보과학회 2022 한국정보과학회 학술발표논문집 Vol.2022 No.12

당뇨신발용 혁의 개발에 관한 연구

이종석,이종철,김명웅,최순복,김영길,유은일 한국공업화학회 2003 응용화학 Vol.7 No.1

The whole process of manufacturing diabatic leather for upper and lining is investigated into raw skin, pelt wet bule, crust leather and finished leather It is tried to make the more functional upper leather and lining leather in the whole leather process by the use of developed recipr. The lower chrommed wet blue for upper and lining is developed through tanning process. The air-permeability of crust leather for upper and lining is incerased through miling The hygiene of finished leather for upper and lining is increased by the of antibacterial and deodorization agents. The upper leathe and lining leather through these have the more improved physical properies of the finished leather than those through other treatments.

당뇨신발용 혁의 개발에 관한 연구

이종석,이종철,김명웅,최순복,김영길,유은일 한국공업화학회 2003 한국공업화학회 연구논문 초록집 Vol.2003 No.-