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중국 시장에서 고객 만족 지수의 효과에 관한 연구: 시장 환경의 조절 역할을 중심으로
서해진,조안연,송태호,김태완 부산대학교 중국연구소 2018 Journal of China Studies Vol.21 No.4
By satisfying customer, firms can improve their performance through favorable image, word of mouth, recommendation, and repurchase. Customer satisfaction has been being an important role for both practitioners and academia, and its importance is growing. Companies invest heavily in managing and enhancing customer satisfaction. However, there are mixed conclusions from empirical studies about the effect of customer satisfaction on the financial performance. Hence, we investigate the effect of customer satisfaction on the financial performance of firms. Most of the previous studies on customer satisfaction were conducted on the market in the United States. Results of the US market studies might not reflect the characteristics of other countries. Therefore, it is necessary to examine the effect of customer satisfaction in the Asian market, which can lead to a customer satisfaction management strategy suitable for the individual Asian markets. Also, previous researches mainly examined psychological factors affecting customer satisfaction. However, factors such as the environmental characteristics of the market can affect customer satisfaction as well. Therefore, we examine the effect of customer satisfaction on firms’ financial performance in the Asian markets including Republic of Korea and China from a comparative perspective. We focus on the impact of industry type, different characteristics of products and services on the customer satisfaction formation. Results show that these difference in customer satisfaction formation process can influence on the relationship between customer satisfaction and financial performance. We provide strategic guidelines by comparing two Asian markets dividing industrial types into manufacturing and service industries, and examining the relationship between customer satisfaction and firm’s performance by industry types.
김미란,김정화,서해연,왕현정,김찬국 에너지기후변화교육학회 2015 에너지기후변화교육 Vol.5 No.2
에너지 소양은 우리 삶을 둘러싼 에너지의 특성과 역할에 대한 총체적인 이해와 이를 바탕으로 에너지 쟁점을 파악하고 해결하는 능력을 의미하므로 에너지 교육에서 중요하다. 이 연구는 에너지 소양 논의를 바탕으로 에너지 교육 교재를 분석하여 에너지 교육의 방향을 제안하는데 그 목적이 있다. 이를 위해 에너지 소양에 관한 논의를 바탕으로 에너지 소양 분석틀을 만든 후 국내 에너지 교육 교재를 분석하는데 적용하였다. 연구결과는 다음과 같다. 첫째, 에너지원과 에너지 절약을 다룬 내용 요소들은 전 학년에 고루 언급되고 있으며, 에너지 절약 실천에 그 강조점을 두고 있다. 둘째, 에너지 흐름의 물리적 과정이나 인간의 에너지 사용과 생태계의 관련성, 에너지 의사결정 등에 대한 언급이 매우 제한적이다. 특히, 현재의 에너지 의사결정이 미래세대에까지 영향을 미치게 된다는 시간적 개념의 언급 등은 찾아볼 수 없었다. 에너지 교육 교재는 에너지 소양의 다양한 요소를 균형 있게 다루고, 지구시스템 내에서 이루어지는 에너지 흐름의 물리적・생물학적 과정을 이해하도록 하며, 에너지 의사결정에 영향을 미치는 경제적, 정치적, 환경적, 사회적 요인들을 함께 제시하여야 한다고 제언한다.
박정현,김옥희,김기환,홍하은,서해연,최호중,Joseph Ahn,이태윤,김세준 대한의학회 2019 Journal of Korean medical science Vol.34 No.45
Background: Secretome refers to the total set of molecules secreted or surface-shed by stem cells. The limitations of stem cell research have led numerous investigators to turn their attention to the use of secretome instead of stem cells. In this study, we intended to reinforce antifibrotic properties of the secretome released from adipose-derived stem cells (ASCs) transfected with miR-214. Methods: We generated miR-214-transfected ASCs, and extracted the secretome (miR214-secretome) from conditioned media of the transfected ASCs through a series of ultrafiltrations. Subsequently, we intravenously injected the miR-214-secretome into mice with liver fibrosis, and determined the effects of miR-214-secretome on liver fibrosis. Results: Compared with that by naïve secretome, liver fibrosis was ameliorated by intravenous infusion of miR-214-secretome into mice with liver fibrosis, which was demonstrated by significantly lower expression of fibrosis-related markers (alpha-smooth muscle actin, transforming growth factor-β, and metalloproteinases-2) in the livers as well as lower fibrotic scores in the special stained livers compared with naïve secretome. The infusion of miR-214-secretome also led to lesser local and systemic inflammation, higher expression of an antioxidant enzyme (superoxide dismutase), and higher liver proliferative and synthetic function. Conclusion: MicroRNA-214 transfection stimulates ASCs to release the secretome with higher antifibrotic and anti-inflammatory properties. miR-214-secretome is thus expected to be one of the prominent ways of overcoming liver fibrosis, if further studies consistently validate its safety and efficiency.
백광열,김기환,박정현,Jae Im Lee,김옥희,홍하은,서해연,최호중,안요셉,이태윤,김세준 생화학분자생물학회 2020 Experimental and molecular medicine Vol.52 No.-
The limitations of stem cells have led researchers to investigate the secretome, which is the secretory materials in stem cells, since the principal mechanism of action of stem cells is mediated by the secretome. In this study, we determined the antifibrotic potential of the secretome released from miR-150-transfected adipose-derived stromal cells (ASCs). The secretome released from ASCs that were transfected with antifibrotic miR-150 was obtained (referred to as the miR150 secretome). To validate the antifibrotic effects of the miR-150 secretome, we generated in vitro and in vivo models of liver fibrosis by treating human hepatic stellate cells (LX2 cells) with thioacetamide (TAA) and subcutaneous injection of TAA into mice, respectively. In the in vitro model, more significant reductions in the expression of fibrosisrelated markers, such as TGFβ, Col1A1, and α-SMA, were observed by using the miR-150 secretome than the control secretome, specifically in TAA-treated LX2 cells. In the in vivo model, infusion of the miR-150 secretome into mice with liver fibrosis abrogated the increase in serum levels of systemic inflammatory cytokines, such as IL-6 and TNF-α, and induced increased expression of antifibrotic, proliferation, and antioxidant activity markers in the liver. Our in vitro and in vivo experiments indicate that the miR-150 secretome is superior to the naive secretome in terms of ameliorating liver fibrosis, minimizing systemic inflammatory responses, and promoting antioxidant enzyme expression. Therefore, we conclude that miR-150 transfection into ASCs has the potential to induce the release of secretory materials with enhanced antifibrotic, proliferative, and antioxidant properties.