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박유준 고요아침 2018 한국동시조 Vol.- No.11

Malignant Mesothelioma of the Spermatic Cord

박유준,공혁준,장현찬,신홍석,오훈규,박재신 대한비뇨의학회 2011 Investigative and Clinical Urology Vol.52 No.3

Primary tumors arising from the spermatic cord are very rare. Mesothelioma derives from the mesothelial cells lining the serous membrane, such as the pleura, peritoneum, and tunica vaginalis of testis. Paratesticular malignant mesothelioma (MM), which usually presents as a hydrocele or intrascrotal mass, accounts for 0.3% to 1.4% of MMs. MMs of the spermatic cord account for less than 10% of paratesticular MMs. We report a case of MM of the spermatic cord in a 65-year-old man who primarily presented to the hospital with a left inguinal mass. Following the diagnosis after surgery, he was found to have a contralateral right inguinal mass and died in 6 months. Despite their rare occurrence in the spermatic cord, MMs need to be suspected, especially in patients with a history of asbestos exposure.

The Decoupling within the Korean Music Streaming Industry: The Growth of YouTube Music and the Downturn of MelOn

박유준,김성철 한국통신학회 2023 韓國通信學會論文誌 Vol.48 No.11

YouTube has assisted the Korean music industry by enabling the globalization of K-pop with a utilization of global audience and recommendation algorithms. YouTube and YouTube Music – a subsidiary service of itself – have not only become influential enough to represent the global media trend but have also been impeding local regions. Therefore, it is critical to understand the rise of YouTube Music and the downturn of local leader, MelOn. The purpose of this study is to investigate the unprecedented decoupling phenomenon in the Korean music streaming industry, exploring the factors that led to the lost momentum of local leader, MelOn, and the global player YouTube Music’s outperformance of MelOn. A mixed method, combining a business model and SWOT analysis, was conducted to discover the competitiveness of each service provider. The findings indicate that MelOn is inescapably losing consumers to the global giant owning competitiveness across multiple dimensions. The research holds practical implications to sustain the local music industry and provides an academic lens to analyze similar cases in other local industries threatened by global players.

Is Increased Prostatic Urethral Angle Related to Lower Urinary Tract Symptoms in Males with Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms?

박유준,배권호,진병수,정현진,박재신 대한비뇨의학회 2012 Investigative and Clinical Urology Vol.53 No.6

Purpose: The prostatic urethra is a bent tube, and the clinical significance of the prostatic urethral angle (PUA) was recently reported. We investigated the statistical significance of an increased PUA on the International Prostate Symptom Score (IPSS) in men with benign prostatic hyperplasia (BPH)/lower urinary tract symptom (LUTS). Materials and Methods: A retrospective analysis was done of 270 men with BPH/LUTS from July 2009 to June 2011. Prostate volume, PUA, and intravesical prostatic protrusion (IPP) were measured by transrectal ultrasonography (TRUS). The IPSS was analyzed separately as storage and voiding symptom score. In order to minimize the effect of prostate size on voiding, patients with prostate size over 40 ml were excluded. Results: The mean age was 62.0±9.3 years. The mean prostate volume was 29.0±5.5 ml (range, 20 to 40 ml), and median PUA and IPP were 34o (range, 12 to 52o) and 1.7 mm (range, 0 to 5.3 mm), respectively. The mean IPSS, mean IPSS-ss, and mean IPSS-vs were 19.0±8.2, 7.3±4.0, and 11.6±5.5, respectively. The prostate volume had no statistically significant correlation with IPSS, IPSS-ss, or IPSS-vs. IPP had a statistically significant correlation with IPSS (p<0.001), IPSS-ss (p<0.001), and IPSS-vs (p<0.001). PUA had no statistically significant correlation with IPSS or IPSS-ss. However, PUA had a significant correlation with IPSS-vs (p=0.047). Comparing a higher PUA (≥34o) with a lower PUA (<34o), patients with a higher PUA had a higher IPSS (p=0.001) and a higher IPSS-vs (p=0.001). There was no significant difference in IPSS-ss, prostate volume, or PSA between the two groups. Conclusions: IPP showed significantly correlated with the IPSS and voiding symptom score was affected by the PUA but not by the prostate volume. As the PUA increased, the patients' voiding symptoms worsened. Further study may be needed. Purpose: The prostatic urethra is a bent tube, and the clinical significance of the prostatic urethral angle (PUA) was recently reported. We investigated the statistical significance of an increased PUA on the International Prostate Symptom Score (IPSS) in men with benign prostatic hyperplasia (BPH)/lower urinary tract symptom (LUTS). Materials and Methods: A retrospective analysis was done of 270 men with BPH/LUTS from July 2009 to June 2011. Prostate volume, PUA, and intravesical prostatic protrusion (IPP) were measured by transrectal ultrasonography (TRUS). The IPSS was analyzed separately as storage and voiding symptom score. In order to minimize the effect of prostate size on voiding, patients with prostate size over 40 ml were excluded. Results: The mean age was 62.0±9.3 years. The mean prostate volume was 29.0±5.5 ml (range, 20 to 40 ml), and median PUA and IPP were 34o (range, 12 to 52o) and 1.7 mm (range, 0 to 5.3 mm), respectively. The mean IPSS, mean IPSS-ss, and mean IPSS-vs were 19.0±8.2, 7.3±4.0, and 11.6±5.5, respectively. The prostate volume had no statistically significant correlation with IPSS, IPSS-ss, or IPSS-vs. IPP had a statistically significant correlation with IPSS (p<0.001), IPSS-ss (p<0.001), and IPSS-vs (p<0.001). PUA had no statistically significant correlation with IPSS or IPSS-ss. However, PUA had a significant correlation with IPSS-vs (p=0.047). Comparing a higher PUA (≥34o) with a lower PUA (<34o), patients with a higher PUA had a higher IPSS (p=0.001) and a higher IPSS-vs (p=0.001). There was no significant difference in IPSS-ss, prostate volume, or PSA between the two groups. Conclusions: IPP showed significantly correlated with the IPSS and voiding symptom score was affected by the PUA but not by the prostate volume. As the PUA increased, the patients' voiding symptoms worsened. Further study may be needed.

Randomized Controlled Study of MONARCⓇ vs. Tension-free Vaginal Tape Obturator (TVT-OⓇ) in the Treatment of Female Urinary Incontinence: Comparison of 3-Year Cure Rates

박유준,김덕윤 대한비뇨의학회 2012 Investigative and Clinical Urology Vol.53 No.4

Purpose: Transobturator approaches to midurethral sling surgery are one of the most commonly performed operations for female stress urinary incontinence throughout the world. However, very few results of randomized clinical trials of transobturator midurethral sling surgery (MONARC vs. TVT-O) for the treatment of female urinary incontinence have been reported. In this study, we compared the 3-year follow-up cure rates of these two procedures. Materials and Methods: From July 2006 to June 2008, 74 patients who had undergone MONARC (35 patients) or TVT-O (39 patients) were included in the study and were analyzed prospectively. The mean follow-up duration of both groups was 39.2 months. Preoperative and postoperative evaluations included physical examination, uroflowmetry and postvoid residual measurement, involuntary urine loss with physical activity, and urinary symptoms. Cure of female urinary incontinence was defined as patient report of no loss of urine upon physical activity. The patients’ satisfaction after treatment was rated as very satisfied, satisfied, equivocal, and unsatisfied. Very satisfied and satisfied were considered as the satisfied rate. Results: There were no significant differences in preoperative patient characteristics, postoperative complications, or success rate between the two groups. The cure rate of the MONARC and TVT-O groups was 85.7% and 84.6%, respectively. The patient satisfaction (very satisfied, satisfied) rate of the MONARC and TVT-O groups was 82.8% and 82.1%, respectively. Conclusions: The MONARC and TVT-O procedures were equally efficient for the treatment of female urinary incontinence, with maintenance of high cure rates for 3 years. Longer follow-up is needed to confirm these results. Purpose: Transobturator approaches to midurethral sling surgery are one of the most commonly performed operations for female stress urinary incontinence throughout the world. However, very few results of randomized clinical trials of transobturator midurethral sling surgery (MONARC vs. TVT-O) for the treatment of female urinary incontinence have been reported. In this study, we compared the 3-year follow-up cure rates of these two procedures. Materials and Methods: From July 2006 to June 2008, 74 patients who had undergone MONARC (35 patients) or TVT-O (39 patients) were included in the study and were analyzed prospectively. The mean follow-up duration of both groups was 39.2 months. Preoperative and postoperative evaluations included physical examination, uroflowmetry and postvoid residual measurement, involuntary urine loss with physical activity, and urinary symptoms. Cure of female urinary incontinence was defined as patient report of no loss of urine upon physical activity. The patients’ satisfaction after treatment was rated as very satisfied, satisfied, equivocal, and unsatisfied. Very satisfied and satisfied were considered as the satisfied rate. Results: There were no significant differences in preoperative patient characteristics, postoperative complications, or success rate between the two groups. The cure rate of the MONARC and TVT-O groups was 85.7% and 84.6%, respectively. The patient satisfaction (very satisfied, satisfied) rate of the MONARC and TVT-O groups was 82.8% and 82.1%, respectively. Conclusions: The MONARC and TVT-O procedures were equally efficient for the treatment of female urinary incontinence, with maintenance of high cure rates for 3 years. Longer follow-up is needed to confirm these results.

소옥천 유역의 토지이용 변화에 따른 대청호 수질환경에 대한 지리적 분석

박유준,이민부 한국지역지리학회 2014 한국지역지리학회 학술대회 Vol.2014 No.2

PD-L1 Testing in Gastric Cancer by the Combined Positive Score of the 22C3 PharmDx and SP263 Assay with Clinically Relevant Cut-offs

박유준,고지원,나희영,곽윤진,이근욱,안상훈,박도중,김형호,이혜승 대한암학회 2020 Cancer Research and Treatment Vol.52 No.3

Purpose We provide a comparison between 22C3 pharmDx and SP263 assay, for evaluating programmed death ligand 1 (PD-L1) expression in advanced gastric cancer (GC) patients. Materials and Methods The PD-L1 immunohistochemistry by 22C3 pharmDx and SP263 assays was performed in the center of the tumor (CT) and invasive margin (IM) in 379 GC tissues using tissue microarrays and interpreted as combined positive score (CPS) and tumor proportion score (TPS). Of the total samples, 55 samples were independently reviewed by five pathologists. Results The two assays showed a high correlation in both the CPS and TPS. At a CPS ! 1 cut-off, 219 (57.8%) and 231 (60.9%) GCs were positive for PD-L1 with the 22C3 and SP263 assays, and at ! 10 cut-off, 37 (9.8%) and 36 (9.5%) GCs were positive, respectively. The overall percent agreement (OPA) was greater than 90% with CPS ! 1 and ! 10 cut-offs, and TPS ! 1% and ! 10% cut-offs. There was higher OPA between the two assays with a CPS cut-off ! 10 (99.2%) than ! 1 (94.7%). The percent agreement between the CT and IM was higher with a CPS cut-off ! 10 (92.9%) than ! 1 (77.6%). Patient with positive expression at CPS ! 5 cut-off had a significantly better outcomes in both assays. Interobserver variability among five pathologists was higher than the assay variability. Conclusion Two assays for PD-L1 expression in GC showed high agreement. These results provide guidance for selecting eligible patients with GC for pembrolizumab treatment.

PEMFC 고분자 막 제조 시 어닐링 조건이 고분자 막 내구성에 미치는 영향

박유준,이미화,오소형,박권필 한국공업화학회 2020 한국공업화학회 연구논문 초록집 Vol.2020 No.-

PEMFC 고분자 막 개발 시 가장 중요한 것은 성능과 내구성이다. 막의 성능과 내구성을 높이기 위해서는 막의 안정성을 얻기 위해 행하는 어닐링 조건이 중요하다. 그러나 어닐링 조건에 따른 고분자 막의 내구성에 관한 연구결과가 부족한 실정이다. 따라서 고분자 막의 어닐링 조건 중 온도를 변화 시켜 막의 내구성 평가를 진행하여 기초자료를 제공하고자 하였다. 본 연구에서 어닐링 온도는 135~165℃로 막을 제조하였다. 화학적 내구 평가 방법으로 막을 Fenton 반응(30% 과산화수소+10 ppm FeSO₄) 시켜 용액을 채취하고 불소이온을 측정하여 어닐링 최적 온도 조건을 확인하고자 하였다. 각 조건에서 어닐링 한 시편을 WAXS, TGA/DTG 분석해서 고분자 막 구조와 결정화도가 내구성에 미치는 영향을 연구하였다. 어닐링 온도가 높을수록 막의 열화 속도가 감소된 것을 확인하였으며, 최적의 조건은 165℃인 것을 확인하였다.

강릉지역 폭염특보 발효 기간 동안의 도심 및 주변지역 열지수 비교 분석

박민완,김건태,김선정,이진화,김유준,남형구,안보영,전계학,심재관,최병철 한국기상학회 2016 한국기상학회 학술대회 논문집 Vol.2016 No.10

기상관측차량의 GPS 가강수량 산출 및 검증

김유준,최병철,함태진,심재관,김건태,김선정,박민완,한상옥 한국기상학회 2015 한국기상학회 학술대회 논문집 Vol.2015 No.4