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- 저자 : 문한규 ( Kyu Hyun Park (검색결과 5 건)
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유방현(Bang Hyun Liu),문한규(Han Kyu Moon),허윤(Yoon Huh),양웅석(Ung Suk Yang),강영진(Young Jin Kang),송근암(Geun Anm Song),박현(Hyun Park),유석동(Seuck dong Yo) 대한소화기학회 1988 대한소화기학회지 Vol.20 No.1
N/A To assess of ce11 mediated immunity function, the author examined delayed cutaneous hypersen- sitivity (DCH) responsiveness of Multitest CMI and total lymphocyte count in 41 patients with stomach cancer and 60 healthy subjects as control. The results obtained as follows: 1) In healthy subjects, the average scores of DCH responsiveness were 20.35 mm in male, 10.31 min in female, and 18.50 min in total. There was significant difference between male and female (P<0.01). In the healthy subjects above 40 years old (comparative control group), the average scores wen 19.9 mm in male, 13.5 mrn in female, and 16.3 mm in total. 2) In the stomach cancer group, The average scores were 10.04 min in male, 4.50 min in female, and 8.69 mm in total. The stomach cancer group was divided two group by TMN classification according to the postoperative findings; group A-stage 0, I. II., group B-stage III, IV. The average scores were 13.31 mm in the group A and 6.27 mm in the group B (P<0.01). There was no significant difference between group A and comparative control group. But very significant difference between group B and comparative control grouip was present (P<0.001). 3) Total lymphocyte counts were 2396/mm. In the healthv group, 2602/mm in the group A, 1706/mm in the group B. There was significant difference between the group A and the group B (P < 0.0l). 4) The stomach canncer group vas divided two group by 1300/mm of total lymphocyte count. The average score were 9.98 mm in the group of above 1500 mm of total lymphocyte count and 4.24 mm in the group of below 1500/mm of total lymphocyte count (p<0.01). 5) Tuberculin was the stronger positive DCH responsiveness in the antigen of Multitest CMI in both group. 6) CEA, serum total protein, and serum albumin were not correlated with DCH responsiveness in the stomach cancer group. In conclusion, the Multitest CMI system proved to be safe, rapid, painless, and reproducible means of evaluating DCH to multiple standardized antigen. This procedure offers the potential of detecting changes in cell-mediated immunity in diseased individuals who are skin tested periodically.
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박규현,황순철,곽임수,김홍범,문한규 ( Kyu Hyun Park,Soon Chun Hwang,Ihm Soo Kwak,Hong Bum Kim,Han Kyu Moon ) 대한소화기학회 1981 대한소화기학회지 Vol.13 No.1
The activities of LDH isozymes, transaminases and alkaline phosphatase were studied on 71 cases of liver diseases, among them hepatoma were 27 cases, liver cirrhosis 18 cases and hepatitis 26 cases. The results were as follow: ]. The total activity of LDH in normal control was 171.48+66.37 unit and the fractions of LDH isozymes from LDH-1 to LDH-5 were 30. 655. 81%, 35. 67+3. 73%, 25. 13+3. 83o, 4. 61W3. 08% and 4, 03 2. 73% respectively. 2. The total activity of serum LDH was significantly increased in the cases of liver diseases to compare with those of normal control group. 3, The fractions of LDH-4, LDH-5 and the ratios of LDH-5/LDH-I, LDH-5/LDH-4 and LDH-4+5/LDH-1+2 were significantly increased and LDH-2 and LDH-3 were decreased in the cases of liver diseases to compare with those of normal control. 4. LDH-4+5/LDH-I+2, GOT and alkaline phosphatase were significantly increased in hepatoma than in liver cirrhosis, the fractions of LDEI-5/LDH-1, LDH-5/LDH-4, LDH-4+5/ LDH-I+2 and GOT, GPT were increased in hepatitis than in liver cirrhosis. Nevertheless, there was no significant difference between hepatoma and hepatitis.
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박원일(Won Il Park),이종협(Jong Hyup Lee),조심현(Shim Hyun Jo),백봉력(Bong Luck Paik),최충경(Chung Keung Choi),이성근(Seung Geun Lee),문한규(Han Kyu Moon),최영미(Young Mee Choi),정윤석(Yoon Sok Jung),이관우(Kwan Woo Lee),김현만(Hyeon 대한내과학회 2002 대한내과학회지 Vol.62 No.3
N/A Background: There is increasing interest in the use of a very low calorie diet (VLCD) as a treatment regimen for weight loss in obese subjects. This study was designed to investigate the effect s and safety of a traditional Korean very-low-calory diet Methods: Twelve hospitalized obese patients at Dong Eui hospital in Busan city from May 1998 to December 1998 were selected. Height, body weight, blood lipids, blood insulin level, body fat, lean body mass, subcutaneous fat and visceral fat were measured. A traditional Korean VLCD was supplied for 14 days. Results: Patient's body weight was significantly decreased from 83.8 kg to 78.6 kg, body fat from 32.2 kg to 28.6 kg, lean body mass from 32.2 kg to 28.6 kg, and BMI from 31.4 to 29.5, respectively (p <0.05). Total fat was significantly decreased from 807 cc to 659 cc, subcutaneous fat from 567 cc to 473 cc, visceral fat from 273 cc to 185 cc, respectively. However there were no significant changes in minerals. After VLCD intervention, total cholesterol was significantly decreased from 199 mg/dL to 166mg/dL, HDL-cholesterol from 42 mg/dL, to 35mg/dL, triglyceride from 158mg/dL, to 75mg/dL (p<0.05). The insulin area under the curve was also significantly decreased from 205μIU/mL·2hr to 168 μIU/mL·2hr(p <0.05). Conclusion: Above findings suggested that a traditional Korean VLCD is effective and safe for short term use in terms of reducing body fat and improving insulin resistance in obese patients. (Korean J Med 62:250-257, 2002)
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정소영,이정화,박원일,문한규,박영래,송수복,백봉력,조심현,윤상조,장원익,홍재락 대한내과학회 2002 대한내과학회지 Vol.62 No.2
Strongyloides stercoralis is an intestinal nematode which infects a large portion of the world's population especially in tropical areas and other hot, humid regions. Because of an opportunistic nature of the parasite, the infection is confined to the intestinal tract in immunocompaetent hosts. But, in individuals having immunocompromised state, the parasite is augmented by autoinfection, resulting in hyperinfection and/or systemic dissemination. In Korea, several cases of strongyloides hyperinfection were reported since 1959, especially who had corticosteroid therapy and other immunosuppressive medications. We experienced a case of strongyloides hyperinfection, accompanied with terminal stage of stomach cancer. The patient responded to treatment with albendazole. After one month later, repeated follow-up stool exam revealed clearance of the larvae from the patient' feces. So, we report this case with the literature.(Korean J Med 62:230-233, 2002)
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김동수,이용규,김상순,김용기,이민기,이광욱,김상욱,박규현,양웅석,김상호,문한규,허윤,도창호,손덕현,최장락,강필증 대한내과학회 1990 대한내과학회지 Vol.39 No.2
Insulinoma is characterized by fasting hypoglycemia, various neuropsychiatric symptoms, and those caused by secondary to hypoglycemia. A 21-year-old female was admitted due to frequent loss of consciousness and dull mentality for a year and three months. She was diagnosed as insulinoma on the basis of Whipple's triad, celiac, and mesenteric angiography, abdominal C.T, scan, and the inappropriately elevat level of the insulin and C-peptide in the serum. When we transferred her to the Department of General Surgery for the remaval of insulinoma, a large mass was revealed in the pancreatic head portion with the invasion of the adjucent structures. Thus they performed Whipple's operation. Histologic examinations by light and electron microscopy showed islet cell tumor and many secretary granules in the cytoplasm. A brief review of the literature was made.
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