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박원일(Won Il Park),이종협(Jong Hyup Lee),조심현(Shim Hyun Jo),백봉력(Bong Luck Paik),최충경(Chung Keung Choi),이성근(Seung Geun Lee),문한규(Han Kyu Moon),최영미(Young Mee Choi),정윤석(Yoon Sok Jung),이관우(Kwan Woo Lee),김현만(Hyeon 대한내과학회 2002 대한내과학회지 Vol.62 No.3
N/A Background: There is increasing interest in the use of a very low calorie diet (VLCD) as a treatment regimen for weight loss in obese subjects. This study was designed to investigate the effect s and safety of a traditional Korean very-low-calory diet Methods: Twelve hospitalized obese patients at Dong Eui hospital in Busan city from May 1998 to December 1998 were selected. Height, body weight, blood lipids, blood insulin level, body fat, lean body mass, subcutaneous fat and visceral fat were measured. A traditional Korean VLCD was supplied for 14 days. Results: Patient's body weight was significantly decreased from 83.8 kg to 78.6 kg, body fat from 32.2 kg to 28.6 kg, lean body mass from 32.2 kg to 28.6 kg, and BMI from 31.4 to 29.5, respectively (p <0.05). Total fat was significantly decreased from 807 cc to 659 cc, subcutaneous fat from 567 cc to 473 cc, visceral fat from 273 cc to 185 cc, respectively. However there were no significant changes in minerals. After VLCD intervention, total cholesterol was significantly decreased from 199 mg/dL to 166mg/dL, HDL-cholesterol from 42 mg/dL, to 35mg/dL, triglyceride from 158mg/dL, to 75mg/dL (p<0.05). The insulin area under the curve was also significantly decreased from 205μIU/mL·2hr to 168 μIU/mL·2hr(p <0.05). Conclusion: Above findings suggested that a traditional Korean VLCD is effective and safe for short term use in terms of reducing body fat and improving insulin resistance in obese patients. (Korean J Med 62:250-257, 2002)