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성인병 검진을 위해 내원한 60세 이상 노인에게서 연령증가에 따른 질환의 분포
김용훈(Yong Hoon Kim),곽현진(Hyun Jin Kwak),정홍배(Hong Bae Jeong),안명수(Myoung Soo Ahn),염주협(Ju Hyup Yum),조대경(Dae Kyoung Cho),남홍우(Hong Woo Nam),이홍순(Hong Soon Lee),유수웅(Soo Wong Yoo) 대한내과학회 1999 대한내과학회지 Vol.56 No.2
N/A With increasing life expectance and improvement of the overall health of the elderly, the understanding of geriatric disease becomes an important aspect of medical services. In the elderly, the frequencies of hypertension, DM, & anemia are increased according to aging and renal function is decreased progressively. As screening test for cervical cancer Papanicolaou smear is recommended due to its cost-effective benefits in females. In age-adjusted elderly male and female study populations, authors investigated the alterations of the above diseases, hypercholesterolemia, liver disease, obesity, & proteinuria distributions. Methods : This study included 1,181 aged 40 years (600 males, 581 females) visitors between January 1, 1997 and December 31, 1997 in National Medical Center, Seoul, South Korea. Authors divided these populations into two large groups such as group A and B. Group A was composed of 40-59 years, group B 60 years and older. Group A and B were subdivided into 4 subgroups each other, such as A-1, A-2, A-3 and A-4, B-1, B-2, B-3 and B-4 by means of age-adjusted dividing scale. We used our inclusion criteria to define each disease. Results : Hypertension was the most common disease in males of group B, but obesity was in females. The age-adjusted frequencies of hypertension, anemia, obesity & proteinuria were increased according to aging in the elderly aged 60 years and older. Though hypercholesterolemia revealed non-specific distribution in each group, increased frequency was observed in females compared to males in group B. With increasing their age, abnormal findings of Papanicolaou smear were found in females of group B. Conclusions : As the frequencies of hypertension, anemia, obestiy, proteinuria & abnormal findings of Papanicolaou smear were increased in the elderly aged 60 years and older as increasing their age. Much more attentions and follow up plans for these disease should be needed in the elderly.
1998년 1월부터 9월사이에 발생한 Malaria 의 임상적 고찰
김용훈(Yong Hoon Kim),곽현진(Hyun Jin Kwak),정홍배(Hong Bae Jeong),안명수(Myoung Soo Ahn),남홍우(Hong Woo Nam),이홍순(Hong Soon Lee),유수웅(Soo Wong Yoo),정예경(Ye Kyeong Jeong),이성은(Seong Eun Lee) 대한내과학회 1999 대한내과학회지 Vol.56 No.4
N/A Objective : Annually, the prevalence of indigenous and imported malarial infections is steadily increasing since 1993 in Korea. In order to understand the current characteristics of malarial infections and to prevent, the present research reviewed twenty-seven cases between January and September 1998. Method : In this study, all the twenty-seven (twenty- six patients) cases were obtained from admitted patients between January and September 1998. We had performed routine blood chemical studies, peripheral blood thin and thick smear, physical examination and abdominal sonography. Any patient with a previous history of a narcotic drug injection or had blood transfusion was excluded. Results : Twenty cases (74.1%) were indigenous and seven (25.9%) were imported malaria. Yeonchon-Gun (nine cases) was the most prevalent area in the indigenous cases; Cambodia (three cases) were the most one in the imported cases. Peripheral blood thin smear revealed Plasmodium vivax in all (100%) indigenous malaria, while four cases (57.1%) were P. vivax and one (14.3%) was P. falciparum and two (28.6%) were mixed infections with P. vivax and P. falciparum in the imported cases. In a 3-month period between July and September, peak prevalence (80.4%) was observed. The negative conversion of peripheral blood smear was achieved much earlier in the indigenous (3.9±1.4day) than in the imported (5.7±1.9day) after the treatment but, was not statistically signifcant. Conclusion : Plasmodium ovale was the only unique causative species in the indigenous malaria. Also Yeonchon-Gun and Cheolwon-Gun had been the most important endemic areas as previous reports. One relapse case had been occurred in the imported malaria. On the basis of our data, more efforts for control of malaria should be necessary for eradication and prevention of indigenous and imported malarial infections in Korea.
증예(症例) : 감초 복용에 의한 저칼륨마비가 발생한 노인 1예
이근숙 ( Keun Sook Lee ),김상용 ( Sang Young Kim ),전용덕 ( Yong Deok Jeon ),조영중 ( Young Jung Cho ),남홍우 ( Hong Woo Nam ) 전북대학교 의과학연구소 2010 全北醫大論文集 Vol.34 No.2
저자드은 전신 무력감과 양측 다리의 근무력감을 주소로 내원한 80세 여자 환자에서 감초에 의한 의인성 외견상 염류 코르티코이드 과다증후군(apparent mineralocorticoid excess syndrome)을 진단 하였고 환자의 임상경과를 기존의 문헌 고찰과 함께 보고하는 바이다. Prolonged ingestion of licorice can hypermineralocorticoidism with sodium retension and potassium loss, edema, increased blood pressure and depression of rennin-angiotensin-aldosterone system. We describe a 80-year old woman with muscle weakness with hypokalemia(serum K+: 1.6 mEq/L) and rhabdomyolysis(urine myoglobin> 2000 ng/mL) due to licorice tea. After quitting the licorice and potassium replacement therapy, hypokalemia and muscle weakness gradually improved within 5 days.
김학산,남홍우,민경완,송형운,정경은 대한소화기학회 1991 대한소화기학회지 Vol.23 No.4
Spontaneou bacterial peritonitis is a serious problem in patients with cirrhotic ascites, with an incidence of 10% to 27% in hospital admission and mortality over 40%. The conventional method of ascitic fluid culture has a low sensitivity in detecting causative organism of spontaneous bacterial peritonitis. We have prospectively 1) compaired the sensitivity of two culture methods (conventional vs blood culture bottle method with thioglycollate broth) in cirrhotic patients with spontaneous bacterial peritonitis, 2) determined the optimal inoculation volume of ascites, 3) identified the causative organism of SBP. During the 12 month period,$quot;twenty two episodes of SBP occured in 46 patients with cirrhotic ascites. The conventional method grew an oirganism in 5 episodes whereas the blood culture bottle method did in 16 episodes (22.7% VS 72.7%, $lt; 0.05). Ten-mililiter inoculation of ascites into a blood culture bottle were superior to 5-mililiter inoculation in detecting organism, but not significantly (72.7%(59.0%, p$gt;0.05). We concluded that the inoculation of ascitic fluid to a blood culture bottle is more sensitive than the conventional method and shoule be used routinely for ascitic culture in cirrhotic patients.
윤광식,최창균,안병진,남홍우,정안철,이원자,이종수 대한감염학회 1998 감염 Vol.30 No.2
최근 저자들은 파푸아뉴기니에서 20일 동안 근무하고 귀국후 발병한 열대열 말라리아를 quinine 및 doxycycline으로 치료하여 호전되었다가 다시 5개월 후와 8개월 후에 삼일열 말라리아가 발병한 혼합감염 말라리아 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. We experienced a case of mixed infection with Plasmodium falciparum and P. vivax in a 48-year old Korean man. He returned to Korea from Papua New Guinea, where he worked for 20 days. Approximately one month after return to Korea, he developed high fever and myalgia. Malaria was suspected and he was admitted to our hospital. The peripheral blood smear demonstrated ring forms of P. falciparum. He was treated with quinine and doxycycline successfully. However, fever and myalgia reappeared five months later. This time, the peripheral blood smear showed gametocytes of P. vivax, while indirect immunofluorescence antibody test revealed high titers to both P. vivax and P. falciparum. He was treated with chloroquine and primaquine. Three months later, vivax malaria recurred again; he was treated with chloroquine and higher dose of primaquine. The patient was well after 6 months of follow-up. We hereby report a case of mixed malaria infections with a review of literatures.
담즙산으로 유도된 백서의 췌장손상에 대한 Prostaglandin E1의 효과
서정일,양진석,김학산,남홍우,이봉휘,송형운,지영구,이태광,한창순,한길로 대한소화기학회 1991 대한소화기학회지 Vol.23 No.2
To elucidate the cytoprotective effect of prostaglandin on pancreatic injury, we measured the mortality rate, the degree of pancreatic necrosis, and serum amylase level after prostaglandin E₂ administration in acute experimental pancreatitis which was induced by the retrograde injection of 5% sodium taurocholate into the biliopancreatic duct of rat. Prostaglandin E₁ (100 ㎍/㎏ Body Weight) were injected subcutaneously after 1 and 6 hour later after taurocholate injection, and normal saline solution (1 ㎖) to the control group by same method. The obstained results were as follows: 1) The mortality rate upto 72 hour was not different (11%: VS 29 %) in both group, but mortality rate upto 96 hour was significantly reduced in prostaglandin group compared with that of control group (11% vs 58% p$lt;0.05). 2) The mean serum level of anylase of control group was 773±55.2U and that of prostaglanin group was 772±61.1 U, which were not significantly different each other. 3) The degree of pancreatic necrosis was also reduced in prostaglandin group compared with control group. In conclusion, the present study suggest that prostaglandin E₂ will have a benefical effect on the course of acute pancreatic injury induced by sodium taurocholate.