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1998년 1월부터 9월사이에 발생한 Malaria 의 임상적 고찰
김용훈(Yong Hoon Kim),곽현진(Hyun Jin Kwak),정홍배(Hong Bae Jeong),안명수(Myoung Soo Ahn),남홍우(Hong Woo Nam),이홍순(Hong Soon Lee),유수웅(Soo Wong Yoo),정예경(Ye Kyeong Jeong),이성은(Seong Eun Lee) 대한내과학회 1999 대한내과학회지 Vol.56 No.4
N/A Objective : Annually, the prevalence of indigenous and imported malarial infections is steadily increasing since 1993 in Korea. In order to understand the current characteristics of malarial infections and to prevent, the present research reviewed twenty-seven cases between January and September 1998. Method : In this study, all the twenty-seven (twenty- six patients) cases were obtained from admitted patients between January and September 1998. We had performed routine blood chemical studies, peripheral blood thin and thick smear, physical examination and abdominal sonography. Any patient with a previous history of a narcotic drug injection or had blood transfusion was excluded. Results : Twenty cases (74.1%) were indigenous and seven (25.9%) were imported malaria. Yeonchon-Gun (nine cases) was the most prevalent area in the indigenous cases; Cambodia (three cases) were the most one in the imported cases. Peripheral blood thin smear revealed Plasmodium vivax in all (100%) indigenous malaria, while four cases (57.1%) were P. vivax and one (14.3%) was P. falciparum and two (28.6%) were mixed infections with P. vivax and P. falciparum in the imported cases. In a 3-month period between July and September, peak prevalence (80.4%) was observed. The negative conversion of peripheral blood smear was achieved much earlier in the indigenous (3.9±1.4day) than in the imported (5.7±1.9day) after the treatment but, was not statistically signifcant. Conclusion : Plasmodium ovale was the only unique causative species in the indigenous malaria. Also Yeonchon-Gun and Cheolwon-Gun had been the most important endemic areas as previous reports. One relapse case had been occurred in the imported malaria. On the basis of our data, more efforts for control of malaria should be necessary for eradication and prevention of indigenous and imported malarial infections in Korea.
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성인병 검진을 위해 내원한 60세 이상 노인에게서 연령증가에 따른 질환의 분포
김용훈(Yong Hoon Kim),곽현진(Hyun Jin Kwak),정홍배(Hong Bae Jeong),안명수(Myoung Soo Ahn),염주협(Ju Hyup Yum),조대경(Dae Kyoung Cho),남홍우(Hong Woo Nam),이홍순(Hong Soon Lee),유수웅(Soo Wong Yoo) 대한내과학회 1999 대한내과학회지 Vol.56 No.2
N/A With increasing life expectance and improvement of the overall health of the elderly, the understanding of geriatric disease becomes an important aspect of medical services. In the elderly, the frequencies of hypertension, DM, & anemia are increased according to aging and renal function is decreased progressively. As screening test for cervical cancer Papanicolaou smear is recommended due to its cost-effective benefits in females. In age-adjusted elderly male and female study populations, authors investigated the alterations of the above diseases, hypercholesterolemia, liver disease, obesity, & proteinuria distributions. Methods : This study included 1,181 aged 40 years (600 males, 581 females) visitors between January 1, 1997 and December 31, 1997 in National Medical Center, Seoul, South Korea. Authors divided these populations into two large groups such as group A and B. Group A was composed of 40-59 years, group B 60 years and older. Group A and B were subdivided into 4 subgroups each other, such as A-1, A-2, A-3 and A-4, B-1, B-2, B-3 and B-4 by means of age-adjusted dividing scale. We used our inclusion criteria to define each disease. Results : Hypertension was the most common disease in males of group B, but obesity was in females. The age-adjusted frequencies of hypertension, anemia, obesity & proteinuria were increased according to aging in the elderly aged 60 years and older. Though hypercholesterolemia revealed non-specific distribution in each group, increased frequency was observed in females compared to males in group B. With increasing their age, abnormal findings of Papanicolaou smear were found in females of group B. Conclusions : As the frequencies of hypertension, anemia, obestiy, proteinuria & abnormal findings of Papanicolaou smear were increased in the elderly aged 60 years and older as increasing their age. Much more attentions and follow up plans for these disease should be needed in the elderly.
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박해심,박원,서창인,정연태,유수웅 대한내과학회 1994 대한내과학회지 Vol.46 No.6
There has been no case report of occupational allergy induced by herb materials. We report a case of occupational asthma and rhinintis caused by herb materials, Sanyak (Radix Discorae) and Banha (Rhizoma pinelliae). He has worked to cut herb mateials for three years. He began to feel sneezing, rhinorrhea, coughing and chest tightness since one year ago. Allergy skin prick test revealed positive responses to cat fur (6×4/ 25×24), orchard grass (3×3/23×16), timothy grass (7×7/30×22), rye grass (4×3/25×20), ragweed (2×2/l4×14), Banha extract (2×2/30×25), Sanyak extract (3×3/32×28) and histamine (3×3/25×20), Banha extract (2×2/30×25), Sanyak extract (3×3/32×28) and histamine (3×3/26×$lt;mm$gt;). RAST revealed positive results to g₃(class 2) and e₁, (class 1). The broncho-provocation test showed dual asthmatic response with Sanyak, and early asthmatic response with Banha. Although the initial methacholine bronchial challenge test showed a negative result, airway hyperresponsive ness to methacholine developed at first day after Banha bronchoprovocation test and recovered to normal at seventh day. Specific IgE and IgG₄antibody to Sanyak extract were detected by enzyme linked immunosorbent assay and there was no binding of specific IgG and IgG₄antibody to Banha extract. It is suggested that Sanyak can induce IgE-mediate bronchoconstriction in an exposed worker, and non- immunologic mechanism is suggested on Banha-induced bronchoconstriction.
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이홍순,이학중,박원,한창순,유수웅,주신배,선우인철 대한내과학회 1991 대한내과학회지 Vol.41 No.6
Acute myocardial infarction (AMI) rarely occurs in systemic lupus erythematosus (SLE), but mortality is as high as 50%. Also, AMI is a possible cause of inexplained heart failure in SLE patients. We experienced a case of AMI resulting from coronary vasculitis which was manifested by diffuse sclerotic narrowing of the coronary arteries in coronary angio-graphy in a 36-year-old male lupus patient. Management by prednisolone and post-centrifugal plasma-pheresis decreased systemic symptoms, chest pain, and cardiac enzymes. Follow up coronary angiography also revealed improved sclerotic lesions in the coronary arteries, The patient iss cunently under follow-up tsectment as an out-patient for 20 months with only skin manifestation without heart symtoms.
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