산욕기에 발생한 뇌교출혈로 인한 마비성 사시 환자 치험 1례

김유경,김우성,강세영,심국진,윤지원,백동기,이종덕,원진희,이상관,김홍준,Kim, Yu-Kyung,Kim, Woo-Sung,Kang, Sei-Young,Sim, Kuk-Jin,Yoon, Ji-Won,Baek, Dong-Gi,Lee, Jong-Deok,Won, Jin-Hee,Lee, Sang-Kwan,Kim, Hong-Joon 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.3

Pregnancy related stroke is significant because it has dire impact on both mother and the fetus. Pregnant or puerperal women are reported to have about 13-fold more risk of stroke compared to non-pregnant women. Pregnancy-related stroke must be differentiated from stroke in elderly patients, because it is different in pathophysiological etiologies and recurrence rates and also diagnostic and therapeutic methods may affect the fetal health status. Because the VI cranial nerve manages lateral rectus muscles, it' s palsy causes sudden onset of double vision. The eyes turn medially. In this article, one case of paralytic strabismus resulting from pontine hematoma during puerperium is reported. It was treated with herb medicine and acupuncture. Symptoms improved. This case is submitted with a brief overview of related lit.

윤작이 감자 수량, 토양 화학성 및 미생물 활성에 미치는 영향

김유경,강호준,양상호,오한준,이신찬,강성근,김형신,Kim, Yu-Kyoung,Kang, Ho-Jun,Yang, Sang-Ho,Oh, Han-Jun,Lee, Shin-Chan,Kang, Seong-Keun,Kim, Hyoung-Sin 한국유기농업학회 2012 韓國有機農業學會誌 Vol.20 No.4

The objective of this study was to determine crop rotation effects on potato yield, soil chemical and microbiological properties from a short-term field experiment from 2010 to 2011 in Jeju Island, Korea. Potato cropping systems included continuous and rotation sequences of soybean (Glycine max(L.) Merr.), barley (Hordeum vulgare var. hexastichon), rapeseed (Brassica napus L.) and broccoli (Brassica oleracea var. italica). Crop rotations increased the yields of potato from 31% to 52% compared with continuous potato. Marketable yield of potato was highest under soybean plus rapeseed rotation by $20.97MT\;ha^{-1}$ and lowest under continuous cropping by $11.95MT\;ha^{-1}$. The incidence and severity of scab disease was significantly lower in tubers from crop rotation with soybean plus barley. Differences in marketable tuber yields among rotations were associated with potato scab disease. Especially, incidence and severity of potato scab were strongly correlated with soil pH, exchangeable calcium, and bacteria population of the soil. Crop rotations significantly increased soil pH, available phosphate, exchangeable K and Ca, especially in crop rotations with soybean plus barley or rapeseed. Soil microbial biomass C of crop rotations with soybean plus barley or rapeseed, was also significantly higher compared with monoculture. In conclusion, crop rotation may decrease the incidence of soil-born pathogen by increasing soil chemical properties and soil microbial biomass. Overall, potato crop productivity was generally maintained in rotations that contained soybean plus barley or rapeseed but declined under continuous cropping system. 본 시험은 윤작처리가 감자의 상품수량과 토양 화학성 및 미생물 활성에 미치는 영향을 평가하고 알맞은 작부체계를 확립하기 위하여 시험을 수행하였다. 작부체계내 콩과 보리를 도입하여 2년 2기작으로 감자를 윤작하였을 경우 총수량과 상품수량은 대조구인 연작구 대비 각각 31% 및 53% 정도 증가하였으며, 콩과 유채를 도입하여 2년 2기작으로 감자를 윤작하였을 경우 총수량과 상품수량은 각각 57% 및 75% 정도 증가하였다. 그리고 감자의 상품수량에 미치는 요인간 상관관계를 분석한 결과 상품수량은 토양미생물 활성, 특히 Biomass C 및 세균 밀도가 높을수록 증가하였고, 토양 pH, 유효인산, 치환성 칼슘함량이 높을수록 세균 밀도가 증가하였다. 따라서 윤작을 통해서 토양 화학성을 개량하고 미생물 밀도 및 활성을 증가시키면, 토양병 발생을 억제하고 감자의 생산성을 높일 수 있을 것으로 판단된다.

인텔리젠트 빌딩에서의 기계자동제어설비의 현재와 미래동향

김유경,Kim, Y.G. 대한설비공학회 1995 설비저널 Vol.24 No.2

Complete genome of the multidrug-resistant Escherichia coli strain KBN10P04869 isolated from a patient with acute myeloid leukemia

김유경,이원길,송경은,Kim, Yu Kyung,Lee, Won Kil,Song, Kyung Eun The Microbiological Society of Korea 2018 미생물학회지 Vol.54 No.4

저자들은 최근 급성골수성백혈병 환자로부터 다제내성대장균 균주 KBN10P04869를 분리했다. 균주는 4,457개의 단백질 코딩 유전자, 88개의 운반 RNA, 22개의 리보솜 RNA를 포함하는 5,104,264 염기쌍으로 구성되고, $^{bla}CMY-2$, $^{bla}TEM-1$, $^{bla}CTX-M-15$, $^{bla}NDM-5$, $^{bla}OXA-18$를 포함한 다제내성유전자를 가지고 있다. 저자들은 이 균주의 총유전체를 보고하는 바이다. Recently, we isolated a multidrug-resistant Escherichia coli strain KBN10P04869 from a patient with acute myeloid leukemia. We report the complete genome of this strain which consists of 5,104,264 bp with 4,457 protein-coding genes, 88 tRNAs, and 22 rRNAs, and the co-occurrence of multidrug- resistant genes including $^{bla}CMY-2$, $^{bla}TEM-1$, $^{bla}CTX-M-15$, $^{bla}NDM-5$, and $^{bla}OXA-18$.

들깨잎 폴리페놀 산화효소의 pH 및 온도에 의한 영향

김유경,김안근,Kim, Yoo-Kyung,Kim, An-Keun 대한약학회 2004 약학회지 Vol.48 No.6

Polyphenol oxidase-catalyzed oxidation of substrates (t-butylcatechol, 4-methylcatechol, chlorogenic acid, caffeic acid and pyrocatechol) were performed in the Ph range 4~8. Co ncentrations of substrate's major oxidation products were monitored by high performance liquid chromatograph. The nature and amounts of products formed were highly pH dependent. They also were ifluenced by kinds of substrates. Major oxidation product of 4-methylcatechol appeared the maxium value at pH 5, them of chlorogenic acid, caffeic acid and pyrocatechol at pH 6.0 and that of t-butylcatechol at pH 5~7. Time-dependent PPO activity was determined at $4^{\circ}C\;and\;30^{\circ}C$. PPO extracted by phosphate buffer containing triton X-114 (t-PPO) was more stable than PPO by phosphate buffer (b-PPO). The result of electrophoresis, at first PPO was showed only a band at 48 kd. After 1~3 days a partial degrade band was appeared in b-PPO and three partial degrade bands in t-PPO. No activity band was appeared in PPOs at $30^{\circ}C$ and b-PPO at $4^{\circ}C$ after 4 days. And a band (37 kDa) in t-PPO was remained finally and disappered. PPO from Perillae leaves has two activity bands at 48 and 37 kDa in previous paper. It was supposed that PPO in the leaves of Perilla frutescens was a protein having one molecular weight as 48 kDa. And 37 kDa protein, relatively proteolysis-resistant, was a proteolyzed form of a major form.

클리펠-트레노네이증후군 환자에서 발생한 재발척수병

김유경,엄영인,주인수,Kim, Yue Kyung,Eom, Young In,Joo, In Soo 대한임상신경생리학회 2015 Annals of Clinical Neurophysiology Vol.17 No.2

Klippel-Trenaunay syndrome (KTS) is a rare congenital malformation syndrome involving blood and lymph vessels, which is characterized by triad of cutaneous hemangioma, venous varicosities, and overgrowth of the affected limbs. Because vascular malformation in KTS can be located anywhere except the face and brain, the clinical presentation could be extremely variable. But there are only rare case reports that KTS is associated with spinal cord lesion. We report a case of recurrent myelopathy in a patient with KTS.

Denosumab (Prolia^®)의 투여 간격 및 칼슘·비타민 D 복합제제 처방 여부에 따른 임상적 결과 평가

김유경,김정현,도현정,정영미,이정화,이주연,김은경,Kim, Youkyeong,Kim, Junghyun,Doh, Hyunjeong,Jeong, Young Mi,Lee, Jeonghwa,Lee, Ju-Yeun,Lee, Euni 한국임상약학회 2022 한국임상약학회지 Vol.32 No.3

Background: Denosumab (Prolia®) is administered every 6 months for osteoporosis treatment. Co-administration of calcium and vitamin D is required to minimize hypocalcemia risk. We evaluated clinical outcomes based on the administration interval of denosumab and co-prescription with calcium-vitamin D combination products. Methods: A retrospective study was conducted using electronic medical records from 668 patients who started denosumab therapy between January 1 and December 31, 2018, at Seoul National University Bundang Hospital. Clinical outcomes, as measured by changes in T-score, were evaluated by the intervals and concurrent prescriptions with calcium-vitamin D combination products. Results: Of the 668 patients, 333 patients met the eligibility criteria. These patients were divided into two groups based on appropriateness of the administration interval: "Appropriate" (304 patients, 91.3%) and "Inappropriate" (29 patients, 8.3%). T-score changes were significantly higher in the "Appropriate" than in the "Inappropriate" group (0.30±0.44 vs. 0.13±0.37, p=0.048). At the beginning of the treatment, 221 patients (66.4%) were prescribed calcium-vitamin D combination products, but the changes in T-scores were not significantly different by the prescription status of the product (0.29±0.46 vs. 0.28±0.38, p=0.919). Conclusion: T-scores were significantly improved in patients with appropriate administration intervals. No significant changes in T-scores were observed by the prescription status with calcium-vitamin D combination products. For optimal treatment outcomes, prescribers should encourage adherence to the approved prescription information on dosage and administration, and pharmacists should provide medication counseling for patients.

객체지향 설계의 특성을 고려한 품질 평가 메트릭스

김유경,박재년,Kim, Yu-Kyung,Park, Jai-Nyun 한국정보처리학회 2000 정보처리논문지 Vol.7 No.2

지금까지의 객체지향 메트릭스에 대한 연구는 단순히 품질의 일부 요소만을 다루고 있으며, 대부분의 메트릭스는 클래스 사이의 관계 정보만을 기반으로 제안되어 왔다. 이로써 객체지향 설계의 특성을 충분히 반영하지 못하고 있다. 또한 기존의 객체지향 메트릭스는 각 메트릭의 계산 결과를 평가하기 위하여 제한값(threshold)을 제공하고 있으며, 형식적으로 정의되지 않은 것이 대부분이다. 이들의 문제점은 계산 과정이 복잡하여 쉽게 적용할 수 없고 프로젝트의 성격이나 소프트웨어의 특성에 따라 제한 값이 달라질 수 있다는 것이다. 이에 본 논문에서는 객체지향 설계의 특성인 크기, 복잡도, 결합도 및 응집도를 고려하여 설계의 품질을 평가하기 위한 메트릭 집합을 제시한다. 제시된 메트릭 집합은 평균값에 대한 비율(proportion)을 사용하여 평균값을 상회하는 클래스 및 설계 요소들을 쉽게 파악할 수 있도록 하였다. 이것은 설계 품질을 저하시키고 있는 클래스를 찾아내어 평균값에 근접한 수준을 h다시 설계할 수 있도록 함으로써, 구현하는 동안 직면하는 설계 결점을 개발 초기에 발견할 수 있도록 하였다. 본 논문에서 정의한 메트릭 집합은 측정원칙에 의하여 분석적으로 평가된다. 그 결과로서 메트릭에 대하여 요구되는 성질의 대부분을 만족하고 있음을 알 수 있다. 도한 플랫폼과 무관하게 사용할 수 있도록 웹 브라우저 및 자바 애플릿으로 개발되어 분산 인트라넷 환경을 지원하는 평가 도구 ASSOD(ASsessment System of Object oriented Design)를 설계한다. There are many researches about metrics to measure a quality of Object-Oriented(OO) software. However, most of them have only discussed a concept or properties of metrics, and have not shown the detailed procedure for measuring them. They also define a measurement indicator as a threshold, but it has been influenced on a project size or application domains. In this paper, we propose metrics based on characteristics of OO design such as size, complexity, coupling and cohesion, and use a propotion to an average as the measurement indicator. It is easy to classify classes which have a result above the average, and to predict classes which reduced the quality of OO design. They will be modified to hold the average. Proposed metrics are analytically evaluated by Weyuker's nine properties. They are satisfied with seven properties except two properties co not apply to OO metrics. Also, we design a quality assessment system, ASSOD(ASsessment System of Object oriented Design), to measure the quality of the OO design independent of the platform.

젊은 과학자상 수상자

김유경,Kim, Yu-Gyeong 한국과학기술단체총연합회 2003 과학과 기술 Vol.36 No.1

'양자 초단면 이론' 으로 거울 대칭현상 해결/ '1조분의 1초'의 '초고속 현상' 연구 탁월/ 극미세 나노물질의 형성 원리 밝혀/ 인체 면역시스템을 분자적 수준서 규명/

객체 추적 연동 다중 PTZ 카메라 제어 기반 객체 중심 다각도 영상 획득 기술

김유경,엄기문,조기성,Kim, Y.K.,Um, G.M.,Cho, K.S. 한국전자통신연구원 2016 전자통신동향분석 Vol.31 No.3

최근 개인화된 미디어의 출현과 더불어 방송통신 미디어 분야에서 개인별 맞춤형 방송 서비스에 대한 관심과 지원이 빠르게 확산되는 추세다. 특히, 다중 카메라를 이용한 관심 인물에 대한 다각도 영상과 같은 차별화된 영상을 제공하려는 수요가 꾸준히 증가하고 있다. 객체 중심의 영상을 생성하기 위한 관련 기술의 발전 및 수요 변화에 발맞춰 본고에서는 관련 기술의 개요 및 연구동향을 살펴보고, ETRI에서 개발 중인 객체 추적 기반의 다중 Pan-Tilt-Zoom(PTZ) 카메라 제어를 통한 객체 중심 다각도 영상 획득 기술을 소개하고자 한다.