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은행엽 물추출물이 흰쥐의 흉부대동맥 혈관이완에 미치는 영향
鄭權洙,金亨煥,安德均,崔湖榮 대한본초학회 2001 大韓本草學會誌 Vol.16 No.2
We have examined the relaxational response of the Ginkgo Folium water extract on isolated thoracic aorta from sprague dawley rat (300~350g) in the presence and absence of endothelium and the vasodilator nitric oxide. Segments of thoracic aorta obtained from rats immediately after delivery were mounted in organ baths superfused on a polygraph. We found that the thoracic aorta segments responded to the Ginkgo Folium water extract with a dose-dependent vasorelaxation. At 2.0 ㎎/㎖ Ginkgo Folium water extract, the relaxational response with and without endothelium were 75.8% and 6.9% of the maximum KCI-response. The Phenylepinephrine and 5-hydroxytrptamine - induced contraction at 10^-4M were inhibited by 77.3% and 75.8% after addition(2.0 ㎎/㎖) of the Ginkgo Folium water extract. After pre-treatment of the thoracic aorta with N^G-monomethyl-L-arginine(10^-4M), the vessels contracted in response to the nitric oxide synthase inhibitor. The present results show that nitric oxide may act as a crucial signal in the vasodilative action. In conclusion, Ginkgo Folium water extract-induced relaxation in the isolated rat thoracic aorta was composed of endothelium-dependent and dose-dependent relaxation. Endothelium-dependent relaxation may be mediated by release of endothelium derived relaxing factor, nitric oxide.
黃紅日,權貞南,金瑩均 동의대학교 한의학연구소 1997 동의한의연구 Vol.1 No.-
Throuth the bibliographical study upon the cause of Bi(痺), next conclusion have been obtained. 1. Insufficiency of Ki-blood(氣血不足) due to weakness of body, and infirmity of nutrient and defensive Ki(營衛不固) were the main endogenous cause of Bi(痺). 2. The exdogenous cause of Bi(痺) were wind evil(風), coldness(寒), and dumpness (濕) which arise from conditions of weather and living circumstance. 3. The other cause of Bi(痺) were stagnation of turbid phlegm and stasis of blood (痰濁瘀血) which flow into viscer and joints along meridian. 4. The various name of Bi(痺) which has been used with the changes of epoch, that is, Baek-Ho(白虎), Yeok-Jeol(歷節), Tong-Pung(痛風) can be concluded in Bi(痺) on a point of view of the same symtoms and causes.
申大澈,權貞南,金瑩均,韓宗鉉,김재석,김재섭 동의대학교 한의학연구소 1997 동의한의연구 Vol.1 No.-
The purpose of this study was to investigate effect of water extract of Patriniae Herba on the poliferation of human cancer cell-lines. The effects of Patriniae Herba on the poliferation of A43l, HeLa, MOLT-4, K562 cells, Balb/c 3T3 cells, mouse thymocytes, splenocytes and human lymphocytes were estimated by MTT colorimetric assay, The results were as follows; 1. Patriniae Herbs did not effect A43l, HeLa, MOLT-4, K562 cells. 2. The cytotoxicity of mitomycin C on MOLT-4 cells was increased by the combination of Patriniae Herba. 3. Patriniae Herba inhibited the proliferation of Balb/c 3T3 cells. 4. Patriniae Herba stimulated the proliferation of thymocytes. 5. Patriniae Herba stimulated the proliferation of splenocytes. 6. Patriniae Herba stimulated the proliferation of human lymphocytes.
正氣天香湯 및 加味正氣天香湯의 效能에 대한 實驗的 硏究
朴贊基,權貞南,金榮均 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1
Effects of Jeongkicheonhyangtang and Kamijeongkicheonhyangtang have been experimentally studies. The results have been obtained as follows: 1. It is proved that analgecic effect on sample I group and sample II group are clearly decreased than control group. Thus, the statistically significant decrease is p<0.005. 2. It is proved that anti-inflammatory effect on sample I group and sample II group are decreased compare to control group. Thus, the statistically significant decrease of sample I group is p<0.05 in 30 and 60-minute, p<0.01 in 90-minute, and p<0.005 in 12 and p<0.005 in 90, 120 and 180-minute. 3. It is proved that appearance of gastric ucler is decreased compare to the control group and the statistically significant decrease is p<0.05. 4. It is proved that plasma epinephrine contents of sample I and II group are clearly decreased compare to the Control Group and the statistically significant decrease is p<0.005 5. It is proved that plasma norepinephrine contents of sample I group is drastically decreased compare to the control group and the statistically significant decrease is p<0.005. 6. It is proved that plasma dopamine contents of sample I and II group are decreased than the control group and statistically significant decrease of the sample I group is p<0.005, and those of the sample II group is p<0.05. As the above mentioned results of experiment, it is believed that Jeongkichenhyang and Kamijeongkicheonhyang have effect for stress.
열처리가 Teflon^(??) FEP film의 전하보존특성에미치는 영향
김성준,이현석,김지균,권정열,이헌용 명지대학교 산업기술연구소 2007 産業技術硏究所論文集 Vol.26 No.-
In this paper, we studied the method of electrets electrode which formed to accumulate negative electric charges by corona discharges. The breakdown voltage samples and damaged samples by various corona discharges have made material stabilization and improved characteristics of electric charge storage throughout the annealing processes. After the experiment made material stabilization nearly melting point by many kinds of annealing conditions, we did the corona discharge again by the charged high voltages, a discharge electrode gap, and a discharged time. As we compared it with the best condition, we confirmed that characteristics of electric charge storages were improved.
서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)
김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2
Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.
Penetration Mechanisms of Ceramic Composite Armor Made of Alumina/GFRP
Jung, Woo-Kyun,Lee, Hee-Sub,Jung, Jae-Won,Ahn, Sung-Hoon,Lee, Woo-Il,Kim, Hee-Jae,Kwon, Jeong-Won Korean Society for Precision Engineering 2007 International Journal of Precision Engineering and Vol.8 No.4
Combat vehicles are frequently maneuvered in battlefields when the lives of combatants are being threatened. These vehicles are important elements that influence the consequences of a battle. Their armor must be lightweight and provide excellent protection to ensure successful operations. Ceramic composite armor has recently been developed by many countries to fulfill these requirements. We reviewed previous research to determine an effective armor design, and then fabricated a composite armor structure using $Al_2O_3$ and glass fiber-reinforced polymer. Specimens were manufactured under controlled conditions using different backing plate thicknesses and bonding methods for the ceramic layer and the backing plate. The penetration of an armor-piercing bullet was evaluated from ballistic protection tests. The bonding method between the ceramic layer and the fiber-reinforced polymer influenced the ballistic protection performance. A bonding layer using rubber provided the best protection.
Jung Darjin,Jung Jin Hee,Kim Jin Hee,Jue Jie Hee,Park Joong Wan,Kim Do Kyun,Jung Jae Yun,Lee Eui Jun,Lee Jin Hee,Suh Dongbum,Kwon Hyuksool 대한의학회 2024 Journal of Korean medical science Vol.39 No.1
Background: Inter-hospital transfers of severely injured patients are inevitable due to limited resources. We investigated the association between inter-hospital transfer and the prognosis of pediatric injury using the Korean multi-institutional injury registry. Methods: This retrospective observational study was conducted from January 2013 to December 2017; data for hospitalized subjects aged < 18 years were extracted from the Emergency Department-based Injury in Depth Surveillance database, in which 22 hospitals are participating as of 2022. The survival rates of the direct transfer group and the interhospital transfer group were compared, and risk factors affecting 30-day mortality and 72- hour mortality were analyzed. Results: The total number of study subjects was 18,518, and the transfer rate between hospitals was 14.5%. The overall mortality rate was 2.3% (n = 422), the 72-hour mortality was 1.7% (n = 315) and the 30-day mortality rate was 2.2% (n = 407). The Kaplan-Meier survival curve revealed a lower survival rate in the inter-hospital transfer group than in the direct visit group (log-rank, P < 0.001). Cox proportional hazards regression analysis showed that interhospital transfer group had a higher 30-day mortality rate and 72-hour mortality (hazard ratio [HR], 1.681; 95% confidence interval [CI], 1.232–2.294 and HR, 1.951; 95% CI, 1.299–2.930) than direct visit group when adjusting for age, sex, injury severity, and head injury. Conclusion: Among the pediatric injured patients requiring hospitalization, inter-hospital transfer in the emergency department was associated with the 30-day mortality rate and 72- hour mortality rate in Korea.