호산구성 육아종에 병발된 동맥류성 두개골 골낭종 : 증례보고 Case Report

길승배,허철,변진수,한용표,김헌주,홍순기,김명순,홍순원,김윤미 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.9

A case of aneurysmal bone cyst(ABC1 secondary to eosinophilic granuloma of the skull is reported. In the skull the presence of ABC secondary to eosinophilic granuloma is rare. We reviewed the clinicopathological and radiological features of this type of eocinophilic granuloma at the cranium.

이온交換樹脂에 있어서 몇가지 金屬이온의 分布係數에 대한 포화유기일염기성산의 效果

金亨昇,韓順滿,金演斗 충남대학교 자연과학연구소 1980 學術硏究誌 Vol.7 No.2

The effects of formic acid, acetic acid, propionic acid and n-butyric acid on the distribution coefficients of magnesium, calcium and strontium ion in Dowex 50W_X8, which is strong acidic cation exchange resin, have been investigated in the various concentrations of the acid. It has been found that the distribution coefficients of the metal ion decreased with the increase of the acid concentration.

비지흥국의 색소 및 Monacolin K 함량

윤은경,김영희,김순동 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2003 한국식품저장유통학회지 Vol.10 No.3

두부폐기물인 비지와 M. Pilosus를 이용한 홍국제조의 가능성을 검토하기 위하여 건조분말 비지에 20%양의 물을 첨가하여 증자한 비지에 glucose(0~10%), monosodium glutamate(0~0.1%), 감귤과피물추출물(감귤과피 양으로 0~0.5%)의 첨가에 따른 색소 및 monacolin K 함량을 조사하였다. Glucose 첨가량을 10%로 하였을 때 색소 생성량이 O.D. 1.06으로 가장 높았으며 이 때의 monacolin K 함량은 96.385㎎%(w/w)이었다. Monosodium glutamate는 0.01%에서 색소 생성량이 O.D. 2.26으로 가장 높았으며 이때의 monacolin K 함량은 118.255㎎%(w/w)이었다. 감귤과피 물추출물(g/mL)의 경우는0.4%(v/w) 첨가하였을 때 색소 생성량이 O.D. 2.61로 가장 높았으며 이때의 monacolin K 함량은 104.505㎎%(w/w)이었다. This study was conducted to investigate the preparation possibility of Beni-koji by Monascus pilosus using dried soybean curd residue(Biji). The additional effect of water(0-50%), glucose(0-10%, w/w), monosodium glutamate(0-0.1%, w/w) and citrus peel water extracts (0-0.5%, v/w) on the pigment and monacolin K content of the Biji Beni-koji were examined. Optimal added amounts of water was 20% of dried Biji. The highest pigment content(OD at 500㎚) of Biji Beni-koji ws 1.06 in 10% glucose, 2.26 in 0.01% Monosodium glutamate and 2.61 in 0.4% citrus peel water extracts. The content of monacolin K in the Biji Beni-koji added with 10% glucose, 0.01% monosodium glutamate and 0.4% citrus peel water extracts showed 96.38㎎%(w/w), 118.25 ㎎%(w/w) and 104.50 ㎎%(w/w), respectively.

대체 소화제의 열역학적 물성 비교

김재덕,여미순,이광진,이윤우,장윤호,노경호 한국화재소방학회 2004 한국화재소방학회논문지 Vol.18 No.1

몬트리올 의정서에 의해서 규제받는 CFCs와 Halon의 대체 물질인 HFC-23, HFC-125, HFC-227ea, HFC-236fa와 불활성 화합물 Ar, N₂, CO₂의 열역학적 물성인 포화압력, 밀도, 엔탈피, 점도를 비교하였다. 본 연구에서는 소화제의 물성을 문헌값을 온도의 함수로서 표시하였다. HFC화합물의 열역학적 물성은 Halon-1301과 비슷하게 나타내었다. 불활성 화합물은 주로 혼합물로 이용되지만, 불활성 화합물의 물성은 Halon-13O1에 비하며 바람직하지 않았다. For CFCs and Halons regulated by Montreal Protocol and their alternatives of HFC-23, HFC-125, HFC-227ea, HFC-236fa and the mixtures of inert gases of Ar, N₂ and CO₂, the thermodynamic properties of saturated pressure, density, enthalpy and viscosity were compared. In this study, the data from literature were expressed as a function of temperature. Thermodynamic properties of HFC compounds were similar to those of Halon-1301. Inert gas was mainly used as a mixture, but the physical properties of the inert gas does not have the favorable advantages over those of Halon-1301.

크롬(Ⅵ)의 체내 흡수와 소실속도에 관한 연구

김현영,이성배,임철홍,이권섭,정용현,이종성,한정희,전윤석,황호순,이용묵 한국산업위생학회 2003 한국산업보건학회지 Vol.13 No.1

The CrO3 mostly used in plating. metal surface disposal, leather, cosmetic manufacturing, as an experiment material by repeatedly inhaling and exposure the male S.D. rats at a 0.00, 0.2., 0.50, 1.25 mg/㎡ concentration(particle size: 0.5-0.5 aerosol)6hours a day, 5day a week in 13weeks comparing with 2weeks, 8weeks of recovery group about the noxiousness of the experiment animal and the reduce scale of the CrO3 in the internal organ especially in blook and respiratory organ with the period of convalescent and clearance. The experiment results which we received are as follows. 1. In blood the RBC, HGB and HCT experiment, rats with 0.20, 0.50 mg/㎡ concentration showed that there were some decreases but not dependent. The kidneys absolute weight compared with control group was reduced intentionally(p〈0.05) and the lungs absolute weight compared with control group showed intentional increase(p〉0.05). 2. After the exposure of the experiment material, the whole blook, l\blood plasma and red blood cell in blood by (x): the period of convalescent, per (y); the decreasing of Cr concentration, was y=66.51 e -0.057x, y=67.2 e-0.101x, y=70.01 e-0.030 in 0.50 mg/㎡ exposure concentration by calculating the clearance coefficient of correlation, and the half life (day)was estimated 12.0, 6086, 23.0 each. 3, After the exposure of the experiment material, the experiment animals lung, liver and kidneys by(x); the period of convalescent, per (y); the decreasing of Cr conentration, was y=1808 e-0.00493x, y=12.02e-0.0297x, y=67.61 e-0.0292x in 0.50mg/㎡ exposure concentration by calculating the clearance coefficient of correlation, and the half life(day)was estimated 140.6, 23.3, 23.7, each, and including lung, liver with all of the experiment internal organs, the Cr clearance decreased as the exposure concentration increased.

1,2-Benzothiazine 계열 새로운 항염진통제에 대한 약리작용 및 대사효소발현 유형의 연구

김상건,조주연,권순경,이은방 德成女子大學校 藥學硏究所 2000 藥學論文誌 Vol.11 No.1

Expression of xenobiotic-metabolizing enzymes can be altered by xenobiotics, which represents changes in the production of reactive metabolic intermediates as well as toxicities in tissues. Metabolic intermediates derived from xenobiotics are considered to produce the reactive oxygen species including drug free radicals and hydroxyl free radicals, which would be ultimately responsible for drug-induced toxicities. The effects of 1,2-benzothiazine anti-inflammatory agents on the expression of xenobiotic-metabolizing enzymes including major cytochrome P450s, microsomal epoxide hydrolase (mEH) and glutathione S-transferase (GST) were studied in the liver with the aim of providing the part of information on potential production of reactive metabolites and hepatotoxicity by the agents. The synthetic compounds 24, 36 and 39 exhibited anti-inflammatory effects in rats as assessed by the Randall-Selitto method. The anti-inflammatory effect was detected as early as at 30 min after gavaging the agents with the ED50 being noted at 80 ㎎/㎏, which was comparable to that of ibuprofen. Treatment of rats with each compound (100 ㎎/㎏,3d) resulted in no significant induction in the immunochemically-detectable cytochromes P450 1A1/2, P450 2B1/2, P450 2C11 and P450 2E1. Changes in the mEH expression were also minimal, as evidenced by both Western blot and Northern blot analyses. Hepatic GST expression was slightly increased by the agents: GST Ya protein and mRNA expression was 1.5-fold increased after treatment with compounds 24 and 39, whereas GST Yb1/2 and Yc1/2 mRNA levels were elevated 2-to 3-fold. In summary, the effects of the synthetic 1,2-benzothiazines on the expression of major P450, mEH and GST were not significant, providing evidence that methbolic activation of the agents, potential drug interaction and hepatotoxicity would be minimal.

불활성 기체 혼합물의 물성에 관한 열역학적 실험식

김재덕,여미순,이윤우,노경호 한국화재소방학회 2003 한국화재소방학회논문지 Vol.17 No.2

대체 소화제로 사용되는 불활성 기체 중 Ar, N₂, CO₂에 대한 혼합물에서의 물성(포화압력, 밀도, 점도)에 관한 실험식을 구하였다. Mixing rule에 의해 계산한 값을 이용하여 다항식 등의 회귀분석에 의해서 실험식을 얻었다. 포화압력은 온도에 대하여 1차 실험식으로 표시하였다. 압축인자와 포화압력을 이용하여 온도에 대한 밀도에 관한 실험식을 제시하였다. 점도는 온도에 대한 지수함수로 표시하였다. Ar, N₂, CO₂ 혼합물의 조성이 40/50/10(mol. %)에서 열역학적 실험식을 구하였다. For the inert gases of Ar, N² and CO², the empirical equations of the gas mixture were correlated in terms of saturated pressure, density and viscosity. They were obtained by regression analysis based on the mixing rule. The empirical equation of saturated pressure was assumed as the first order function of temperature. The empirical form of density was expressed as compressibility factor and saturated pressure while the empirical equation of viscosity was formulated as a power function of temperature. This empirical equations of the physical properties were obtained in the composition of Ar, N² and CO², 40/50/10 (mol. %).

불활성 기체에 대한 열역학적 실험식

김재덕,여미순,이윤우,노경호 한국화재소방학회 2003 한국화재소방학회논문지 Vol.17 No.1

Halon 대체 소화제로 쓰이는 불활성 기체 중 Ar, N₂, CO₂의 단일 성분일 때의 물성(포화압력, 밀도, 점도)에 관한 실험식을 구하였다. 문헌에서 얻은 실험값을 이용하여 다항식 등의 회귀분석에 의해서 실험식을 얻었다. 포화압력은 온도에 대하여 각각 2차와 3차의 실험식으로 표시하였다. 밀도는 Ar, N₂는 온도에 대한 1차 함수로 표시하였고, CO₂는 온도에 대하여 각각 2차와 3차의 실험식으로 표시하였다. 점도는 온도에 대한 지수함수로 표시하였다. 이들 실험식을 이용하여 단일 성분일 때의 상태를 알 수 있다. Inert gases, Ar, N₂, CO₂, as a Halon alternative, the empirical equations were correlated in terms of saturated pressure, density and viscosity. They were obtained by regression analysis from the experimental data in the literature. The empirical equations of saturated pressure were expressed as the second and third order function of temperature. The empirical equation for Ar and N₂ of density were expressed as the first order function of temperature. And CO₂ was expressed as the second and third order function of temperature. The empirical equation of viscosity was formulated as a power function with temperature. This empirical equations would allow us to predict pure component state.

중간탄성지점을 갖는 부분고정단 보의 탄성임계하중

김순철,문연준 東新大學校 1996 論文集 Vol.8 No.-

The finite element method is used for the study of the elastic critical load of partially fixed end beams with, intermediate elastic supports. The elastic critical loads of beams are investigated by changing the numbers of elastic supports and their stiffness also by changing Kinney's fixity factor, f_a. The results show that the elastic critical loads of beams are increasing with the increasing Kinney's fixity factor, f_a and with the increasing numbers of intermediate elastic support. The critical loads show a general trend that they converge to a certain value.

심첨부 비후 심근증에서 심근 내 미세 관상동맥의 혈류 예비력 평가 : 경흉부 도플러 심초음파를 이용한 연구 Study Using Transthoracic Doppler Echocardiography

윤호중,박철수,신재원,임상현,조은주,정해억,전희경,오용석,정욱성,김재형,최규보,홍순조 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.3