2형 당뇨 환자에 있어서 C형 간염의 유병률에 관한 연구

김구영,서광섭,유광렬,임병욱,채선애,강남훈,김창훈,권영우,김희수,류성태,이정환,박성우,오웅식,김정한 중앙대학교 의과대학 의과학연구소 2003 中央醫大誌 Vol.28 No.1

Background: We have doubt about the truth that Type 2 DM is associated with chronic hepatitis C infection. The aim of our study was to prove a close relationship between chronic HCV infection and type 2 DM in korean patients. Methods: We reviewed the out-patient's medical records of 466 patients with type 2 DM who visit the Sung-ae hospital from March 2000 to August 2001. Diabetic patients were analyzed for the following variables: age, sex, waist circumference, weight, waist/hip ratio, using of self monitoring of blood glucose, method of therapy, duration of disease, experience of previous transfusion, major surgical procedure, accompanied disease, liver function tests (LFT), HbA1 c. We ruled out patients with liver cirrhosis. Results: Hepatitis C virus infection was observed more frequently in patient with Type 2 DM. Of 466 Type 2 DM patients, 13 patients were infected with Hepatitis C virus (2.79%). Compared with mean prevalence of Korean population (1.3~1.6%), it's value is very high. the other hand, 21 patients were infected with Hepatitis B virus (4.5%). Such results are similar to mean prevalence of the general public (4~5%). Conclusions: Prevalence of hepatitis C was closely associated in korean patients with type 2 DM. And an increased prevalence is independent of cirrhosis.

만성 알코올 중독환자에서의 경련

류상효,송홍기,이주헌,박환석,남경식 대한간질학회 2003 대한간질학회지 Vol.7 No.1

고삼투압성 비케톤성 상태의 예후인자

안성훈,김양원,김미란,진헌철,안지영,이상래,류석용,김홍용,김성준,이병권,김경환 대한응급의학회 2001 대한응급의학회지 Vol.12 No.2

Background: A hyperosmolar nonketotic state has been known to have a high mortality, and even now, despite this high mortality, only a few studies of this disease have been performed. We studied the prognostic factors for the hyperosmolar nonketotic state. Methods: We retrospectively studied the cases of 40 patients who were in a hypersomolar nonketotic state when admitted to Sanggye Paik Hospital during the 6-year Period from 1995 through 2000. We divided the hyperosmolar nonketotic patients into two groups, the complete recovery group and the incomplete recovery group, and compared the clinical features, the laboratory findings, and the precipitating factors between two groups. Results: 1) A total of 40 patients were studied: 24 in the complete recovery group and 16 patients in the incomplete recovery group. The mortality rate was 32.5%. 2) No significant statistical difference existed among the clinical features of the two groups, except for the sex(p<0.01). 3) Among the laboratory findings of both groups, analysis revealed that the effective osmolarity was significantly higher among those in the incomplete recovery group(p<0.01). Serum sodium concentration was also significantly higher among those in the incomplete recovery group(p<0.01). Serum creatinine was also significantly higher among those in the incomplete recovery group(p<0.05). Serum bicarbonate concentration, on the other hand, was significantly lower among those in that group(p<0.05).4) Infection was identified as the most common precipitating factor(62.5%). Among the precipitating factors of the two groups, there were significant statistical difference in pneumonia, UTI, and inappropriate glucose control. 5) A significant statistical difference existed among the initial level of consciousness of both groups(p<0.05). 6) The only significant independent factor responsible for prognosis of nonketotic hyperosmolar state patients was the sex. Conclusion: The sex was only significant independent prognostic factor of nonketotic hyperosmolar state patients.

관상동맥 질환에서 도플러 심초음파도로 측정한 확장기 좌심실기능의 지표와 혈역학적 소견과의 비교 검토

임헌관,기신영,유창범,최태명,김성구,권영주 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1

Background : Left ventricular diastolic dysfunction is now recognized as a significant cause of cardiac symptoms even in patient with normal systolic ventricular function. During the last several years, the use of Doppler echocardiography for assessing left ventricular diastolic function has attracted increased attention. Doppler study have demonstrated that patients with ischemic heart disease have abnormal diastolic filling pattern suggesting impaired relaxation. Methods : This study was designed to correlate Doppler mitral flow velocity patterns and measuared variance with hemodynamic findings in 33 patients: 10 with myocardial infarction(group 1), 10 with angina pectoris(group 2) and 13 with no coronary disease(group 3). Results: 1. E/A ratio (0.87±0.24 m/sec versus 1.09±0.91 m/sec, P<0.05) was lower in group 1 than in group 3. 2. Significant correlation were demonstrated between pulmonary capillary wedge pressure (PCWP) and isovolumic relaxation time(IVRT) (r=-0.58; p<0.001), and E velocity (r=0.61; p<0.005). 3. IVRT was (61±30msec versus 92±35msec, p<0.05) shorter in patients with PCWP>10mmHg than in patients with PCWP≤10mmHg. Conclusion: Doppler mitral flow recordings have partially clinical potentiality in assessing left ventricalar diastolic function in patient with ischmic heart disease.

Trichoderma viride에서 분리한 Endoglucanases와 Cellulose의 상호작용에 있어서 Enzyme에 존재하는 Trytophan기의 역할

원성미,장영훈,김동원,정영규,류해일 공주대학교 사범대학 과학교육연구소 1996 과학교육연구 Vol.27 No.1

곰팡이 Trichoderma viride 셀룰라아제로부터 세가지의 endoglucanase (endoglucanase Ⅰ,Ⅱ및Ⅲ)가 다양한 크로마토그래피 과정을 통해 분리되었다. 또한 활성에 미치는 tryptophan기의 역할을 화학적 변형을 통하여 알아보았다. N-bromosuccinimide에 의한 효소의 화학적 변형으로부터, endoglucanase Ⅰ,Ⅱ및Ⅲ의 분자당 지니고 있는 tryptophan의 개수가 각각 6,1,1.5개 임을 알수 있었다. 즉 endoglucanase Ⅰ은 분자당 여섯 개의 tryptophan을 함유하고 있으며, 활성부위에는 한 개가 영향을 미치는 것으로 나타났다. 반면에 endoglucanase Ⅱ및Ⅲ는 분자내에 대략 하나의 tryptophan이 단지 활성부위에서만 작용하는 결과를 보여주었다. 또한 endoglucanase Ⅰ의 경우 활성부위가 아닌 다른 부분에 있는 tryptophan기가 기질의 표면에 흡착하는데 미치는 영향을 알아보았다. Three endoglucanases (endoglucanase Ⅰ,Ⅱ and Ⅲ ) as major cellulase components were isolated from the fungus Trichoderma viride by a of chromatography procedures, and the role of tryptophan residues in the activity towards carboxymethyl cellulose were investigated through kinetic and chemical modification studies. Through the modification of cellulase with N-bromosuccin-imide, it was found that endoglucanase Ⅰ,Ⅱ and Ⅲ contained 6, 1, and 1.5 tryptophan residue(s) per enzyme molecule, respectively. From the result of the kinetic data on the modification, it was estimated that the active site of enzyme includes at least one or two tryptophan residue. These results indicated that, in the case of endoglucanase Ⅰ, five tryptophan residues are exposed to another region of the enzyme except that of active site. In the case of the endoglucanase Ⅱ and Ⅲ, however, tryptophan residue exists almost in the active site. In addition, the relationship between endoglucanase activity towards cellulose and the role of tryptophan residue exposed to the enzyme surface was discussed.

재량적 발생액의 기업가치평가요소에 대한 노이즈효과

金東憲,柳成容 홍익대학교 동북아연구소 2002 東北亞硏究 Vol.6 No.-

This study examines the association between valuation and accrual information. According to accounting based valuation model, firm's value consists of net book value and abnormal earnings. Net book value and abnormal earnings are determined as the manager's accounting policy. Discretionary accruals may signal the manager's value expectation or be noisy factor of accounting based valuation variables. The results of this study are as follows; First, discretionary and non-discretionary accruals are not associated to stock prices. This result suggests that discretionary accruals and non-discretionary accruals are not factors of the firm value. Second, the product term of discretionary accrual and net book value are associated to the stock price negatively but the product term of non-discretionary accrual and net book value are not associated to the stock price. the results indicate that discretionary accruals are noisy factors of net book value information. Third, the product term of discretionary accrual and net income are associated to the stock price negatively and the product term of non-discretionary accrual and net income are also associated to the stock price negatively the results suggest that discretionary accruals are noisy factors of earnings.

배당세와 기업의 배당정책

金東憲,劉成龍 홍익대학교 동북아연구소 2001 東北亞硏究 Vol.5 No.-

Individual investors earn the incomes of dividends and capital gains in investing firm's stocks. Dividend incomes are taxed but capital gains are not taxed according to Korean tax law. The differential taxation of these incomes can force individual investors to value retained earnings and contributed capital differently as the components of net book value. The purpose of this study is to investigate the relationship between dividend tax and firm's dividend policy. Sample firms were collected in the Korean Stock Exchange listed-firms. Results of this study are as follows ; First, Individual investors value retained earnings lower than contributed capital as the components of net book value. This result suggests that individual investors appreciate the dividend tax effect. Second, the dividend tax effect is apparent in high dividend ratio firms rather than in lower dividend ratio firms. This indicates that management can maximize the firm value by means of dividend policy.

地中送電관의 최적 되메움재 선정을 위한 열특성 硏究

윤성중,류권일,고영헌,김팔규 忠南大學校 産業技術硏究所 2003 산업기술연구논문집 Vol.18 No.2

The purpose of this paper is development of the most suitable backfill material which increases thermal stability and decreases thermal resistances for increasing capacity of the transmission of electricity. In order to proceed this study, the sand which recently was used as backfill material and the stone dust as single material for most suitable backfill material was chosen and experiments on thermal character and basic soil properties were proceeded for appreciating stability and economical efficiency. As a result of this study, natural moisture content of stone dust was higher than that of sand and porosity of stone dust and thermal resistance of stone dust was lower than that of sand. Then the stone dust are expected to increase capacity of the transmission of electricity. In point of stability, because total strain of pipe was within allowed strain, two materials are expected to ensure against risks. Stone dust is considered as useful backfill materials by contributing great economical efficiency, because a price of stone dust is half to the sand.

KRISS의 광 측정시스템을 이용한 단일모드 광섬유의 색분산 및 편광모드분산 측정과 불확도 평가

이성헌,김용평,유한영,서호성 慶熙大學校 레이저 工學硏究所 2007 레이저공학 Vol.18 No.-

We demonstrate the uncertainty comparison and analysis of NPL chromatic dispersion(CD) and NIST polarization mode dispersion(PMD) Certified Reference Material(CRM) in the KRISS. The uncertainty of each quantity was evaluated as the combined standard uncertainty multiplied by a coverage factor k=2. Modulation phase shift techniques are used to measure CD in the 1300 nm and 1500 nm region , PMD in the 1500 nm region. CD and PMD uncertainty are 2.64 ps/nm · km, 0.002 ps, respectively. The measurement uncertainty was a good agreement between CD & PMD CRM and PDLA system of KRISS.

EVA/MMT 나노복합체의 제조 및 열적, 기계적 성질에 관한 연구

전철환,류승훈 경희대학교 산학협력기술연구원 2001 산학협력기술연구논문집 Vol.7 No.-

Ethylene vinyl acetate copolymer and montmorillonite nanocomposites were prepared by melt intercalation using HAAKE mixer. The influence of substituted alkylamine in MMTs and molecular weight(melt index) of EVA on the intercalation behavior of EVA/MMT composites were investigated. EVA/MMT composites were analyzed by X-ray diffraction in order to study the changes of MMT interlayer distance. The dimethyl dioctadecyl ammonium ion substituted MMT can exist nano-scale in EVA. Thermal stability of composites is improved about 40℃, and the modulus increases twice for pristine EVA for 10 wt% MMT.