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대학급식의 미생물적 품질보증을 위한 HACCP의 적용 : 참치샐러드 Tuna Salad
김운주,최은희,최현미,배주희,채현숙 충북대학교 교육 ·생활연구소 생활과학연구센터 2002 생활과학연구논총 Vol.6 No.1
The purpose of this study was to evaluate the microbiological quality, and to assure the safety of the food production process in the university foodservice facilities in accordance with the Hazard Analysis Critical Control Point(HACCP) concepts. The kitchen layout and time-temperature relationship, miciobiological quality(total plate count, coliform) were assessed to identify the critical point during each of the production phases. The results were as follows: 1) The kitchen layout had to be improved because contamination area was not separated from non-contamination area, and work table was in contact with washing sink. 2) Some employee did not follow personal hygiene standards(hand washing), and did not wear proper working uniforms(hair restraints). 3) The production time of tuna salad was 120 min, and environment temperature was 20.1~26.0℃. Improper receiving temperature, inproper holding practices(without cover at room temperature) were observed. 4) In the purchasing phase of the raw materials, the microbiological quality of green pepper was not at acceptable level based on the TPC(2.3×10^6CFU/g)and coliform(>14,000 MPN/g). During washing phase TPC was decreased about 3 log cycle. After cutting and holding phase the level of TPC and coliform were increased rapidly. At serving phase the microbiological quality of tuna salad were not at acceptable level(TPC 3.3×10^6 CFU/g, coliform 11,000 MPN/g) according to the standard set(TPC <10^5 CFU/g, coliform <100 MPN/g) by Sorberg et al. 5) For tuna salad, critical control points were purchasing and receiving of fresh vegetables, washing, cutting, holding, mixing and serving phase.
Clinical Experience of Rigid Bronchoscopy in Single Center
Kim, Hyun-Jin,Kim, Sei-Won,Lee, Hye-Yeon,Kang, Hyeon-Hui,Kang, Ji-Young,Kim, Ju-Sang,Kim, Myung-Sook,Kim, Seung-Soo,Kim, Jin-Woo,Yun, Hyeong-Gyu,Kim, Chi-Hong,Kim, Kwan-Hyoung,Moon, Hwa-Sik,Cho, Kwang The Korean Academy of Tuberculosis and Respiratory 2012 Tuberculosis and Respiratory Diseases Vol.72 No.6
Background: The aim of this study was to analyze clinical situations requiring rigid bronchoscopy and evaluate usefulness of rigid bronchoscopic intervention in benign or malignant airway disorders. Methods: We retrospectively reviewed 29 patients who underwent rigid bronchoscopy from November 2007 to February 2011 at St. Paul's Hospital, The Catholic University of Korea School of Medicine. Results: Of the 29 patients, the most frequent underlying etiology was benign stenosis of trachea (n=20). Of those 20 patients, 16 had post-intubation tracheal stenosis (PITS), 2 had tracheal stenosis due to inhalation burn (IBTS) and other 2 had obstructive fibrinous tracheal pseudomembrane (OFTP). Other etiologies were airway malignancy (n=6), endobronchial stenosis due to tuberculosis (n=2), and foreign body (n=1). For treatment, silicone stent insertion was done in 16 cases of PITS and IBTS and mechanical removal was performed in 2 cases of OFTP. In 6 cases of malignant airway obstruction mechanical debulking was performed and silicone stents were inserted additionally in 2 cases. Balloon dilatation and electrocautery were used in 2 cases of endobronchial stenosis due to tuberculosis. In all cases of stent, airway obstructive symptom improved immediately. Granulation tissue formation was the most common complication. Conclusion: Tracheal stenosis was most common indication and silicone stenting was most common procedure of rigid bronchoscopy in our center. Rigid bronchoscopic procedures, at least tracheal silicone stenting, should be included in pulmonary medicine fellowship programs because it is a very effective and indispensable method to relieve critical airway obstruction which needs training to learn.
대한간학회지 제8차 춘계학술대회 초록집 : 구연 ; 생체 간이식에 있어서 간공여를 시행하지 못한 증례 분석
김경식 ( Kim Gyeong Sig ),김주희 ( Kim Ju Hui ),전경옥 ( Jeon Gyeong Og ),최진섭 ( Choe Jin Seob ),김명진 ( Kim Myeong Jin ),이우정 ( Lee U Jeong ),김순일 ( Kim Sun Il ),김유선 ( Kim Yu Seon ),김병로 ( Kim Byeong Lo ),박기일 ( Par 대한간학회 2002 Clinical and Molecular Hepatology(대한간학회지) Vol.8 No.2(S)
한국인 급성 심근경색증 환자에서 좌심실 비대의 형태학적 분류에 따른 임상경과의 차이
김희정 ( Hui Jeong Kim ),정명호 ( Myung Ho Jeong ),윤현주 ( Hyun Ju Yoon ),김용철 ( Yong Cheol Kim ),손석준 ( Seok-joon Sohn ),김민철 ( Min Chul Kim ),심두선 ( Doo Sun Sim ),홍영준 ( Young Joon Hong ),김주한 ( Ju Han Kim ),안영근 대한내과학회 2020 대한내과학회지 Vol.95 No.6
목적: 좌심실의 구조적 변화는 심혈관계 이환율과 사망률의 위험 증가와 관련이 있다고 알려져 있다. 본 연구에서는 급성 심근경색증 환자에서 좌심실 비대와 그 형태적 분류에 따라 임상경과의 차이와 주요심장사건(major adverse cardiac events, MACE)에 미치는 영향을 파악하고자 하였다. 방법: 2014년 1월부터 2015년 10월까지 Korea Acute Myocardial Infarction Registry-National Institute of Health(KAMIR-NIH)에 등록된 환자 중 급성 심근경색증으로 전남대학교병원에 입원한 환자 중에서 관상동맥 중재술을 시술받고 2년 동안 임상 추적 관찰이 되어 분석 가능한 환자 852명(남:여 = 603:249)을 대상으로 하였다. 좌심실의 형태적 구조에 따라 정상군 470명(62.4 ± 12.8세, 남자 389명)과 좌심실비대군 382명(67.1 ± 12.1세, 남자 214명)으로 분류하여, 양군 간의 임상적 특성, 혈액 검사 특성, 심장초음파 및 관상동맥 조영술 소견 및 MACE를 비교·분석하였다. 좌심실 비대군은 좌심실 벽의 상대적 두께(relative wall thickness, RWT)와 좌심실 질량지수(left ventricular mass index, LVMI)에 따라 동심성 재형성군(concentric remodeling; RWT ≥ 0.42, LVMI ≤ 115 g/m<sup>2</sup> in male, ≤ 95 g/m<sup>2</sup> in female), 동심성 비대군(concentric hypertrophy; RWT ≥ 0.42, LVMI > 115 g/m<sup>2</sup> in male, > 95 g/m<sup>2</sup> in female) 및 편심성 비대군(eccentric hypertrophy; RWT < 0.42, LVMI > 115 g/m<sup>2</sup> in male, > 95 g/m<sup>2</sup> in female)으로 세분하여 평가하였다. 결과: 대상 환자를 21 ± 7.8개월간의 임상적 경과 관찰 중에 MACE는 173명(사망 55명, 재발성 심근경색증 26명, 재입원 34명)에서 발생하였다. MACE의 발생은 좌심실 비대군에서 정상군에 비하여 유의하게 높았으며(16.0% vs. 25.5%, p = 0.001), Kaplan-Meier 생존곡선을 이용한 사망률 분석 결과에서 좌심실 비대군이 정상군에 비하여 유의하게 생존율이 낮았다(p = 0.008). 좌심실 비대군의 형태적 분류에 따른 MACE의 분석 결과에서는 편심성 비대에서 MACE의 발생이 유의하게 많았다(동심성 재형성 vs. 동심성 비대 vs. 편심성 비대; 11.2% vs. 15.5% vs. 22.1%, p = 0.046). 결론: 급성 심근경색증 환자에서 좌심실 비대는 불량한 예후와 관련이 있었으며, 좌심실 비대 중 편심성 비대를 동반한 경우에 예후가 가장 불량하였다. 따라서, 한국인 급성심근경색증 환자에서 좌심실 비대를 보이는 경우, 특히 편심성 비대를 동반한 경우에 적극적인 치료가 필요할 것으로 사료되었다. Background/Aims: Left ventricular hypertrophy (LVH) on clinical outcomes in patients with acute myocardial infarction (AMI) is not clear. This study was performed to investigate the effect of abnormal left ventricular geometry on clinical outcomes in Korean patients with AMI. Methods: A total of 852 consecutive patients with AMI were divided into two groups: normal left ventricular geometry (n = 470; 389 males) and LVH (n = 382; 214 males) groups. Major adverse cardiac events (MACEs) were defined as cardiac death, recurrent myocardial infarction, and rehospitalization. Results: During the clinical follow-up period of 21 ± 7.8 months, MACEs developed in 173 patients (20.0%), and the rate was higher in the LVH than normal left ventricular geometry groups (25.5% vs. 16.0%, respectively, p = 0.001). According to Kaplan-Meier survival curves, the MACE-free survival rate was significantly lower in the LVH group than in the left ventricular geometry group (p = 0.008). The rates of MACEs and all-cause mortality differed among the AMI with concentric remodeling, concentric hypertrophy, and eccentric hypertrophy subgroups (11.2% vs. 15.5% vs. 22.1%, respectively, p = 0.046). Eccentric hypertrophy was a predictive factor of MACE according to Cox proportional hazards analysis (hazard ratio 1.804, confidence interval 1.034-3.148, p = 0.038). Conclusions: LVH is a predictor of poor outcomes in patients with AMI, and eccentric hypertrophy is associated with a worse prognosis compared with concentric remodeling and concentric hypertrophy. Therefore, Korean patients with AMI and LVH, especially eccentric hypertrophy, require more careful observation and intensive treatment. (Korean J Med 2020;95:387-397)
Jeong, Hui-Gyeong,Kwon, Oh-Hoon,Park, Ju-Hun,Kim, Sang-Gyun,Kim, Yong-Hyeon,Lee, Ju-Young,Kim, Eun-Ji,Kim, Tae-Ju,Jeong, Sang-Jun Korean AcupunctureMoxibustion Medicine Society 2018 Korean Journal of Acupuncture Vol.35 No.4
Background: The purpose of this study was to investigate electric moxibustion on patients with back pain caused by road traffic accidents. Methods: This was a retrospective study (n = 112) comparing treatment with Korean medicine combined with electric moxibustion (n = 56), and Korean medicine alone (n = 56). Patient gender, age, Numeric Rating Scale (NRS), Oswestry Disability Index (ODI) and EuroQol-5 Dimension (EQ-5D) was recorded for each group at the time of hospital admission. Mean NRS measured weekly, mean ODI and EQ-5D scores were measured 2 weeks post-treatment, and evaluated by paired sample t test. using the Statistical Program for Social Science v. 25.0 for Windows. An independent, two-sample t test was used to test for a significant difference in the decrement of NRS, ODI and increment EQ-5D scores between groups. Results: NRS scores decreased in both groups after 1 week of treatment (electric moxibustion, from $5.13{\pm}0.79$ to $3.86{\pm}0.67$; Korean medicine alone, from $5.18{\pm}0.92$ to $4.30{\pm}0.94$; both p < 0.001). There was a significantly greater reduction in NRS score in the electric moxibustion group ($1.27{\pm}0.59$) than in the Korean medicine alone group ($0.88{\pm}0.61$; p = 0.001). After 2 weeks of treatment, EQ-5D scores increased significantly in the moxibustion group ($0.19{\pm}0.12$) compared with the Korean medicine alone group ($0.13{\pm}0.20$; p = 0.043). After 2 weeks of treatment, NRS and ODI scores decreased in both groups. EQ-5D increased in both groups. Conclusion: We suggest that electric moxibustion treatment may be effective for reducing early-stage back pain in patients with road traffic accident injuries.
대간간학회지 제6차 춘계학술대회 초록집 : 포스터 전시 ; 부분 비장색전술로 확진 및 부분 관해된 특발성 문맥압항진증 1예
김수영 ( Kim Su Yeong ),김병호 ( Kim Byeong Ho ),이승훈 ( Lee Seung Hun ),오주형 ( O Ju Hyeong ),이상목 ( Lee Sang Mog ),김교영 ( Kim Gyo Yeong ),김윤화 ( Kim Yun Hwa ),이주희 ( Lee Ju Hui ),동석호 ( Dong Seog Ho ),김효종 ( Kim Hy 대한간학회 2000 Clinical and Molecular Hepatology(대한간학회지) Vol.6 No.1(S)
( Jin Ah Kim ),( Chang Wook Kim ),( Ji Young Kim ),( Yun Hui Kim ),( Mi Ju Cheon ),( Hee Yeon Kim ),( Jung Myung Kim ),( Yoo Dong Won ),( Se Hyun Cho ),( Jong Young Choi ),( Seung Kew Yoon ),( Nam Ik 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1
Aims: Immune regulatory molecules such as forkhead box P3 (FoxP3), programmed death-1 (PD-1) and cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) on T cell are associated with antiviral effector T cell dysfunction, which influences on T cell exhaustion and persistent viral infection in patients with chronic hepatitis C (CHC) and chronic hepatitis B (CHB). These FoxP3, PD-1 and CTLA-4 are known to up-regulated in CHC and CHB but, there is few report about the phenotypic changes of these molecules during direct-acting antiviral (DAA) therapy, especially, Daclatasvir and asunaprevir (DCV+ASV) in genotype 1b CHC. We investigated the expression of FoxP3, PD-1 and CTLA-4 during 6 months DCV+ASV treatment in 19 patients with genotype 1b CHC. Methods: Nineteen patients with genotype 1b CHC under DCV+ASV treatment were enrolled for detection of intrinsic inhibitory molecules of T cell signals (PD-1, CTLA4) and extrinsic inhibitory molecule, FoxP3. Peripheral blood mononuclear cells (PBMC) were isolated from these subjects before treatment (T0), 1 month (T1), 3 month (T3), 6 month (T6) and 9 month (T9) during DCV+ASV treatment. The expressions of FoxP3, PD-1, CTLA-4, CD8, CD4 on T cells were monitored by flow cytometry. Results: T cells from patients with CHC before DCV+ASV treatment (T0) showed increased expression of FoxP3, PD-1 and CTLA-4 compared to healthy control. However, T cells from patients with CHC under DCV+ASV treatment showed decreased expression of PD1 and CTLA-4 at T6 compared to T0 significantly. Interestingly, the expression of Foxp3 was sustained at T6 through T0. Conclusions: In CHC, PD-1 and CTLA-4 as inhibitory T cell molecules were down-regulated during 6 months DCV+ASV therapy but, FoxP3 as regulatory T cell marker was sustained during DCV+ASV therapy. This phenomenon could be one of background mechanisms of post-DAA syndrome such as HCC development or reactivation of HBV coinfection after DAA therapy.
Clinical Experience of Rigid Bronchoscopy in Single Center
( Hyun Jin Kim ),( Sei Won Kim ),( Hye Yeon Lee ),( Hyeon Hui Kang ),( Ji Young Kang ),( Ju Sang Kim ),( Myung Sook Kim ),( Seung Soo Kim ),( Jin Woo Kim ),( Hyeong Gyu Yun ),( Chi Hong Kim ),( Kwan H 대한결핵 및 호흡기학회 2012 Tuberculosis and Respiratory Diseases Vol.72 No.6
Background: The aim of this study was to analyze clinical situations requiring rigid bronchoscopy and evaluate usefulness of rigid bronchoscopic intervention in benign or malignant airway disorders. Methods: We retrospectively reviewed 29 patients who underwent rigid bronchoscopy from November 2007 to February 2011 at St. Paul``s Hospital, The Catholic University of Korea School of Medicine. Results: Of the 29 patients, the most frequent underlying etiology was benign stenosis of trachea (n=20). Of those 20 patients, 16 had post-intubation tracheal stenosis (PITS), 2 had tracheal stenosis due to inhalation burn (IBTS) and other 2 had obstructive fibrinous tracheal pseudomembrane (OFTP). Other etiologies were airway malignancy (n=6), endobronchial stenosis due to tuberculosis (n=2), and foreign body (n=1). For treatment, silicone stent insertion was done in 16 cases of PITS and IBTS and mechanical removal was performed in 2 cases of OFTP. In 6 cases of malignant airway obstruction mechanical debulking was performed and silicone stents were inserted additionally in 2 cases. Balloon dilatation and electrocautery were used in 2 cases of endobronchial stenosis due to tuberculosis. In all cases of stent, airway obstructive symptom improved immediately. Granulation tissue formation was the most common complication. Conclusion: Tracheal stenosis was most common indication and silicone stenting was most common procedure of rigid bronchoscopy in our center. Rigid bronchoscopic procedures, at least tracheal silicone stenting, should be included in pulmonary medicine fellowship programs because it is a very effective and indispensable method to relieve critical airway obstruction which needs training to learn.
건강검진 수진자에서 초음파로 진단된 비알코올성 지방간의 임상양상 및 위험인자
오희주 ( O Hui Ju ),최재원 ( Choe Jae Won ),김국현 ( Kim Gug Hyeon ),이은주 ( Lee Eun Ju ),오현아 ( O Hyeon A ),이형철 ( Lee Hyeong Cheol ),김준환 ( Kim Jun Hwan ),김태년 ( Kim Tae Nyeon ),이헌주 ( Lee Heon Ju ) 대한소화기학회 2003 대한소화기학회 추계학술대회 Vol.2003 No.-
<목적> 최근 지방간은 비만, 고인슐린혈증, 인슐린 저항성, 당뇨병, 고중성지방혈증 등의 대사 증후군과 밀접한 관련이 있는 것으로 알려져 있다. 지방간의 자연경과에 대한 연구에서 지방간이 간경변으로도 진행할 수 있음이 보고되면서 그 관심이 증가하고 있다. 저자들은 건강검진 수진자에서 초음파로 진단된 비알코올성 지방간의 임상양상과 위험인자 및 중증도의 예측인자를 알아보고자 하였다. <방법> 2003년 2월 1일부터 2003년 3월 31일까지 본원 건강 검
초음파로 진단된 지방간에서 알코올성 지방간과 비알코올성 지방간의 임상양상
오희주 ( O Hui Ju ),최재원 ( Choe Jae Won ),김국현 ( Kim Gug Hyeon ),이은주 ( Lee Eun Ju ),오현아 ( O Hyeon A ),이형철 ( Lee Hyeong Cheol ),김준환 ( Kim Jun Hwan ),김태년 ( Kim Tae Nyeon ),이헌주 ( Lee Heon Ju ),박원규 ( Park Won 대한소화기학회 2003 대한소화기학회 추계학술대회 Vol.2003 No.-
<목적> 알코올성 지방간과 비알코올성 지방간은 그 임상양상과 조직학적, 생화학적 검사의 유사성으로 인하여 병력청취만이 유일한 구별의 방법이 되고 있다. 이에 저자들은 초음파로 진단된 지방간에서 알코올성 지방간과 비알코올성 지방간의 임상양상 및 생화학적 검사 등을 비교해 보았다. <대상 및 방법> 2003년 2월 1일부터 2003년 3월 31일까지 본원 건강 검진 센터를 방문하여 초음파 검사를 시행한 환자를 대상으로 전향적인 연구를 시행하였다. 검진자 총