정상면역을 가진 환자에서 발생한 복부대동맥의 진균 감염성동맥류 1예

이호영,김태형,추은주,전민혁,이은정,정은정,전성란,박의주,염욱,장원호,황정화,김동훈,김동원 대한감염학회 2008 감염과 화학요법 Vol.40 No.3

감염성동맥류는 드물지만, 치명적인 질환이다. 진성 진균성 감염성동맥류는 더 드물게 발생한다. 진균감염은 사망률과 이환율이 매우 높다. 그러나 증상이 비특이적이고 일반적인 진단방법으로는 민감하게 진단이 되지 않기 때문에 종종 진단이 어렵다. 저자들은 면역이 정상이고 다른 위험인자가 없는 환자에서 복부대동맥에 발생한 진균성 감염성동맥류를 경험하여 이를 보고한다. 컴퓨터 단층촬영과 혈관 수술에 기초하여 진단하였으며, 수술 후 조직배양에서 균이 동정되지는 않았으나 절제한 혈관조직에서 칸디다 감염을 시사하는 발아가 있는 효모균이 관찰되었다. 한국에서 1988년에서 2007년까지 복부에 발생한 감염성동맥류 17증례를 고찰하였을 때 진성 진균성 감염성동맥류는 없었으며, 저자들이 경험한 것이 복부에서 발생한 진균감염성 동맥류로는 첫 증례이다. Infected aneurysms are uncommon, frequently fatal lesions. "True" fungus-infected aneurysms are even rarer. Fungal infections have high morbidity and mortality. However, diagnosis is frequently difficult, since the symptoms are non-specific and standard diagnostic procedures are often insensitive. We experienced a patient with persistent fever and negative blood cultures. The patient was immunocompetent and had no risk factors, and was diagnosed with a fungus-infected aneurysm based on computed tomography and vascular surgery. The vascular tissue revealed some narrow-based budding yeast within the thrombus, suggesting Candida infection. Seventeen cases of infected aneurysm of the abdomen were reported in Korea from 1988 to 2007, although none were "true" fungus-infected aneurysms, making this the first fungus-infected aneurysm of the abdomen in Korea. Prompt diagnostic procedures and aggressive treatment modalities are necessary for patients with occult infection and negative blood cultures, regardless of their immunocompetence, because of the high morbidity and mortality of this condition.

압입하중-변위곡선의 정량적 해석을 통한 가공경화지수의 평가

全銀埰,安政勳,權東一 대한금속재료학회 2001 대한금속·재료학회지 Vol.39 No.12

Continuous indentation test with ball indenter has been studied for years because of its convenience and simpleness. Especially, the test is expected to supersede tensile test. Among tensile properties work-hardening exponents of various steels were evaluated by the test. We newly defined true stress and true strain with contact depth and indentation load. Finite element analysis shows that the contact depth is affected by elastic deflection and pile-up/sink-in. Therefore, the contact depth was calculated with taken both elastic deflection and pile-up/sink-in into account. The work-hardening exponents derived in this study show good agreement to those from tensile test.

내독소로 유발된 삼추성 중이염에서 TNF-α Inhibitor의 효과

전은주,박용수,최영철,이정학 대한이비인후과학회 2000 대한이비인후과학회지 두경부외과학 Vol.43 No.10

강원지역 중소기업의 환경경영 실태와 과제

전영승,박은정 한국산학경영학회 2004 산학경영연구 Vol.17 No.1

본 연구의 목적은 ISO14001 인증 취득 현황조사를 통해 강원지역 중소기업의 환경경영 실태와 과제를 파악하고 환경경영의 활성화를 위한 방안을 모색하는 것이다. 주요 결과를 요약하면 다음과 같다. 첫째, 2003년 4월 현재 우리나라의 ISO14001 인증획득 업체수는 1,215개 업체인데 비해 강원지역 중소기업의 ISO14001 인증획득 업체는 광역지방자치단체 중 최하위 수준인 26개 업체에 불과하였다. 둘째, 인증 미획득 기업들이 인증을 받지 않으려는 이유로 '인증 획득 및 유지에 소요되는 비용이 효익보다 크다'는 점을 제시하였다. 셋째, ISO14001 인증을 획득한 기업이나 ISO14001 인증 미획득 기업이나 인증을 획득한(하려는) 가장 큰 이유는 '기업의 이미지 향상'이었으며, 인증 획득기업이 환경경영시스템 도입 후 얻은 효과도 '기업의 이미지 향상'으로 나타났다. 넷째, ISO14001 인증을 획득한 기업들은 환경경영시스템을 도입할 때 문제점으로 '문서작성 및 비용에 관한 부담'과 '인력 부족'에 관한 응답이 많았다. 위와 같은 연구의 주요 결과를 바탕으로 강원지역 중소기업의 환경경영 활성화를 위한 과제와 방안을 제시하면 다음과 같다. 첫째, ISO14001 인증 미획득 기업 대부분이 ISO14001에 대한 인지도가 낮아 이에 대한 지속적이고 적극적인 홍보와 교육 및 연수제도가 필요하다는 점이다. 둘째, 환경경영 관련 인력이 부족함으로 전문 인력의 양성을 위한 교육프로그램의 실시, 보조금 지급의 확대, 상담부서 및 상담창구의 개설, 관련 정보의 데이터 베이스화나 소프트웨어의 개발이 필요하다. 셋째, 저렴한 비용과 간단한 절차를 통해 인증을 받을 수 있는 중소기업용 공적 인증제도의 신설, 혹은 단체인증제도, 공단 인증제도 등을 적극 고려할 필요가 있다. The purpose of this study is to understand the realities and the subject of environmental management for small and medium-sized companies in Gwangwon area, through surveying the present status as to acquiring the certification of ISO14001, and to seek for a plan to facilitate environmental management. Given summarizing key results, those are as follows. First, while the number of companies in our country which acquired the certification of ISO14001, amounts to 1,215 businesses as of April of 2003, the number of small and medium-sized companies in Gwangwon area which obtained the certification of ISO14001 reached only 26 businesses, the lowest level among metropolitan municipalities. Second, for the reason that companies who didn't acquire the certification, strive not to receive the certification, it did present the point that 'costs to be needed in acquiring and maintaining the certification are larger than practical benefit. Third, the biggest reason for either companies which did not acquire the certification of ISO14001 or companies which did (try to) acquire the certification of IS01400, was 'enhancement of a corporate image,' and the effect after a company who obtained the certification introduced the environmental management system, was also shown to be 'the improvement of a corporate image.' Fourth, many companies who acquired the certification of IS01400 pointed out the response related to 'burden on document creation and costs' and 'lack of manpower' as problems when introducing the environmental management system. On the basis of major results of a study as the above, given presenting the subject and a plan for activating the environmental management of small and medium-sized companies in Gwangwon area, those are as follows. First, because most of companies who did not obtain the certification of IS01400 have low recognition of ISO14001, it needs continuous and positive publicity, education and a training system. Second, it requires to carry out an educational program to nurture professional manpower due to lack of manpower relevant to environmental management, to expand payment of subsidies, to open exclusive-charge department and consulting contact, to have the relevant information be database and to develop software. Third, in order to make the certification obtained through inexpensive costs and simple procedures, it needs to positively consider the creation of public approval system for a small and medium-sized company, group approval system, industrial-complex approval system, and others.

四物湯이 腹腔 Macrophage 의 貪食能에 미치는 影響

全熏,殷載淳,宋正模 대한본초학회 1999 大韓本草學會誌 Vol.14 No.2

Samultang(SMT) consists of Rehmanniae Radix Preparata, Paeoniae Radix Alba, Cnidii Rhizoma and Angelicae Gigantis Radix. SMT enhanced the lucigenin chemiluminescence and the engulfment of fluorescein-conjugated E. coli particles and did not affect the production of nitric oxide in murine peritoneal macrophage. SMT enhanced the production of γ-interferon, interleukin-2 and the cell viability in murine thymocyte, but did not affect the production of interleukin-4. These results indicate that SMT enhances the phagocytosis of macrophage via the stimulation of γ-interferon production in T_H1 cells.

급성 심근경색증 환자에서 혈전용해요법의 시간지연에 영향을 미치는 요인

정진옥,김윤철,성보영,김준경,전준용,류정곤,성인환,전은석 대한순환기학회 1997 Korean Circulation Journal Vol.27 No.8

객체 지향 方法을 이용한 멀티미디어 文書 편집기의 設計 및 具現

전은철,정혜윤,박성한 한양대학교 공학기술연구소 1992 공학기술논문집 Vol.1 No.1

This paper proposed a design technique of multimedia document editing system by using object-oriented methodology and its implementation using object-oriented language. The multimedia document editing system can generate a mixed document which consists of text, image, graphic and video, verifying the results by formatting document and process the information of position per page. The hierachical structured design of the class library is proposed where document processing methodolgy and object-oriented one are employed. The system is implemented with Turbo C++ package which provides object-oriented compiling function on a PC.

위장관의 원발성 B 세포 악성 림프종의 재분류와 bcl-2, cyclin D1, bcl-6 및 p53 발현의 의미

서정균,김태원,김병수,조은택,박찬국,김만우,이미자,전호종 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Background and Objectives : In recent years, the REAL (Revised European American Lymphoma) classification provided a new category of MALT (mucosa-associated lymphoid tissue) lymphoma and mantle cell lymphoma in B cell lymphomas. We have analyzed the expression of bcl-2, cyclin D1, bcl-6 and p53 and correlated with the subtypes and histologic grade of primary gastrointestinal B cell lymphoma. Also we investigated the usefulness of immunophenotypic features in diagnosis of low grade B cell lymphoma. Materials and Methods : Twenty-two cases of primary gastrointestinal B cell lymphoma were recategorized in low grade MALT lymphoma, low/high grade MALT lymphoma, high grade MALT lymphoma, and diffuse large cell lymphoma according to the morphological findings. We investigated the expression of bcl-2, cyclin D1, bcl-6 and p53 by immunohistochemical method. Results : The bcl-2 protein expression was higher in the low grade MALT lymphoma than in the high grade lymphoma. The cyclin D1 protein expression was negative in all cases. The expression of bcl-6 and p53 protein was negative in all low grade MALT lymphoma. Conclusion : The results suggest that we can differentiate the low grade lymphoma from the high grade lymphoma by immunohistochemical staining for bcl-2, bcl-6, and p53 protien.

만성 강박장애 환자의 정서처리 특성 : 정신분열병 환자 및 정상인과의 비교

석정호,김재진,전종희,이홍식,안석균,이은,김찬형 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.3

Objectives : Obsessive compulsive disorder (OCD) tends to take chronic course as schizophrenia. Researchers reported that OC patients had idiosyncratic sensitivity to threat-related information, while schizophrenic patients were reported to have affec-tive blunting. We hypothesized that there might be a difference in emotional response between OCD and SPR in cronic phase. Methods : Eight different emotional tasks were done by 25 healthy controls, 21 OCD patients and 25 SPR patients. Visual stimuli were made by pairing two words or pictures. Four kinds of emotional stimuli (positive, negative, combined and neutral)were presented to subjects through monitor and they were asked to report their subjective feelings by pushing mouse button, In the combined condition, a pair of positive words (or pictures) and negative words (or pictures) were presented simultaneously. The responses and response time were recorded and analyzed using SPSS 9.0 package. Results : In the negative condition, OCD group didn't show any deficit compared to healthy group. But SPR group showed significantly lower appropriate response rate than healthy group, In the combined condition, OCD and healthy control group Showed 'negativity bias' which SPR group didn't show. In the positive condition, however, OCD and SPR groups did show Significantly lower appropriate response rate than healthy controls. Conclusion : Our results suggested that OCD patients may not have deficits in the processing of negative emotion even in the chronic phase but to have a specific deficit in positive emotion. This result supports the 'threat-relatedness hypothesis' on attentional bias of OCD.

20대 여성의 구두 착용에 따른 발의 장애분석

한현정,전은경 울산대학교 2005 생활과학논문집 Vol.7 No.1

본 연구의 목적은 현대여성의 구두 착용에 따른 발 및 주변 부위의 문제점을 밝히는데 있다. 본 연구에서는 주된 구두 소비자 계층인 20대 여성들을 대상으로 소비자 설문조사를 통하여 구두 착용현황 및 그에 따른 발 장애를 살펴보고 구두 제작시 필요한 기초자료를 제공하고자 하였다. 본 연구의 결과를 살펴보면, 구두 착용여성의 대부분이 연령과 착용시간에 관계없이 많은 장애를 경험하였다. 그러므로 구두장애 요인 중 가장 많이 지적된 ‘구두골 치수’와 소재의 개선이 요구된다. 특히, 발둘레 치수에 대해서는 소비자와 판매자의 인지도가 약해 적절히 사용되지 못하고 있으므로 KS 규격에 대한 홍보가 필요하다. The purpose of this study was to identify the problems of women’s feet and it’s relative area caused by wearing shoes. This study was conducted through a survey with 384 young women consumers of 20s. Most respondents indicated that problems while wearing shoes. The reasons of the discomfort were ‘unfit of the size’ and ‘inappropriate materials.’ Most respondents were found to have the knowledge of their sizes but not of the letter sizes for the foot girth. Seventy six percent indicated that they of the respondents rarely know about the letter size. Most of the respondents (92.5%) indicated that they never checked the letter size when purchased shoes. This implicates that consumer education concerning the ‘KS G 3405 Lasts for shoes’ size system is necessary.