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박원봉,문유선,권영주,주혜진 서울여자대학교 자연과학연구소 2003 자연과학연구논문집 Vol.15 No.-
베타카로틴의 물에 대한 용해도는 담즙산염의 임계미셀농도에서 급속히 증가하였으며, 혼합미셀을 형성시 용해도가 더욱 우수하였다. 또한, 베타카로틴을 수용화 하는데 필요한 계면활성제의 최적비율은 1:5이며, 글리세롤, 레시틴, STPP, 젤라틴, 카라기난 등 각종 안정화제를 적절한 비율로 첨가하여 업자크기를 측정한 결과, 0.48 μm 의 안정된 혼합미셀 조성불을 얻을 수 있었으며, 이 조성불은 항산화활성이 거의 그대로 유지됨을 알수 있었다. β-Carotene is a member of hydrophobic pigments known as carotenoids, which are responsible for the bright warm colors in some fruits and vegetables, β-Carotene is an important antioxidant which protects the body from free radicals. The body converts β-carotene, a nontoxic vitamin A precursor, to vitamin A as needed. Dissolution in surfactant solutions above the critical micelle concentration offers one approach to the formation of poorly soluble materials in solution form. In the present study, the β-Carotene was dissolved in mixed micelles of bile salts (sodium cholate and sodium deoxycholate). Water-solubility of β-Carotene was estimated by measuring absorbance and phase diagram of water/β-Carotene/bile salts system was plotted. Effects of stabilizer on the stability of soluble β-Carotene was estimated by measuring the size of mixed micelles containing β -carotene. Antioxidative activity of hydrophobic and aqueous β-Carotene was estimated by measuring TBA value of linoleic acid emulsion incubated with anti oxidative components.
건강보험공단 건강검진과 자비 건강검진 수검자간의 만족도 비교
신연수,박종연,정상혁,정혜영,강혜영 한국의료QA학회 2005 한국의료질향상학회지 Vol.12 No.1
Backgrouds : This study was performed to compare the satisfaction levels for health examination programs provided by between the Korea National Health Insurance Corporation (KNHIC) and private healthcare organizations in Korea. We investigated factors associated with the satisfaction level for the KNHIC health examination. Also, factors explaining for the additional receipt of private healthcare organization's examination were identified. Methods : A self-administered questionnaire survey was conducted in June 2004 with 250 beneficiaries of the KNHIC industrial workers' program and 100 beneficiaries of the KNHIC selfemployed program. A total of 297 completed the questionnaire, including 213 (85.2%) and 84 (84.0%) for each insurance program. Ten questions measuring satisfaction levels for each examination program were rated on a scale ranging from 1 (strongly unsatisfied) to 5 (strongly satisfied). Results : Among the subjects receiving both examinations, the mean satisfaction level for the KNHIC examination (3.07) was significantly lower than that for the private healthcare organization's examination (3.50) (p<0.05). The KNHIC examination showed lower satisfaction for all of the 10 items than the counterpart. In particular, the KNHIC examination had the scores of lower than 3.0 for the items reflecting post-examination management services. According to the multiple regression analysis results, the satisfaction for the KNHIC examination was positively associated with the positive attitude toward health examination(•‚=0.38, p<0.00). The logistic regression results showed that the likelihood of receiving the private healthcare organization's examination in addition to the KNHIC examination increases as the respondents were less healthier(OR=0.29, 95% CI = 0.10¢¶0.84), the satisfaction level for the KNHIC examination decreased(OR=0.46, 0.28¢¶0.75) or the attitude toward health examination was more positive (OR=2.56, 1.31¢¶5.12). Conclusion : The relatively low satisfaction level for both examination programs suggests that there's ample room for improvement of health examination services in Korea. The negative association between additional receipt of private healthcare organization's examination and satisfaction level for the KNHIC examination implies that the improvement of the satisfaction for the KNHIC examination would help to reduce the national expenditure spent on the additional examination.
The detecion of African swine fever virus via hair plucking: An alternative non-invasive approach
Chae-Rin Park(Chae-Rin Park),Tae-Young Suh(Tae-Young Suh),Da-Hye Yi(Da-Hye Yi),Soo-Kyoung Lee(Soo-Kyoung Lee),Seong-Keun Hong(Seong-Keun Hong),Ki-Hyun Cho(Ki-Hyun Cho),Jee-Yong Park(Jee-Yong Park),Yon 한국예방수의학회 2022 한국예방수의학회 학술대회자료집 Vol.2022 No.-
( Hye Yon Park ),( Yoon Jung Lee ),( Jun Hee Lee ),( Min Ji Lee ),( Jong Kyun Lee ),( Kyu Taek Lee ),( Kwang Hyuck Lee ) 대한내과학회 2013 The Korean Journal of Internal Medicine Vol.28 No.5
The solid pseudopapillary tumor (SPT) of the pancreas is a rare but low-grade malignant tumor with a good prognosis after surgical excision. Endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) is a minimally invasive, safe and reliable way of diagnosing SPT by providing characteristic cytological and immunochemical specimens. Definitive preoperative diagnosis leads to targeted and minimally invasive surgical resection. In this study, we report three cases of SPTs that were diagnosed through EUS-FNA and underwent successful laparoscopic surgery.
( Hye-yon Cho ),( Ryeobin Lee ),( Ye Hyon Park ),( Tae-yeem Lee ),( Sung-taek Park ),( Sung-ho Park ),( Jeong Bae Kang ),( Pong Rheem Jang ),( Min Sun Kyung ) 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-
목적: To investigate the impact of laparoscopic hysterectomy (LH) on ovarian reserve by comparing changes of serum anti-Mullerian hormone (AMH) levels following LH (study group) and laparoscopic myomectomy (LM; control group). 방법: Serum AMH levels were measured pre-operatively (AMH0), 7 days (AMH1), 2 months (AMH2), and 6 months (AMH3) after LH and LM in 40 premenopausal women (LOC=20; LM=20). Changes of AMH were compared between two groups. 결과: Total 40 women included in this study (LOC=20; LM=20). At postoperative 6 months, 35 women checked AMH3. On the baseline data analysis, mean age was younger in LM group compared to LH group (p= 0.031). Parity and BMI was similar in both groups. AMH0 was similar in both groups (2.4 ± 2.72 in LM vs. 1.5 ± 3.52 in LH, p= 0.370). Also, AMH1, AMH2, and AMH3 were not different between the two groups. A rate of a significant decrease of AMH (more than 50% decrease compared to AMH0) at postoperative 6 months was not different between the two groups. 결론: Serum AMH levels were not significantly decreased after LH compared to LM, which suggests that LH may have no adverse effects on ovarian reserve comparing to LM. A long-term study of AMH levels is required.
박희옥(Hee Ok Park),박종연(Chong Yon Park),강혜영(Hye Young Kang),조우현(Woo Hyun Cho),정혜영(Hye Young Chung) 한국병원경영학회 2001 병원경영학회지 Vol.6 No.1
There has been pointed out that a great portion of hospitalized patients stay in hospitals longer than necessary, often even after the completion of necessary care. This causes that hospital resources are not used efficiently. In order to identify underlying forces in postponing inpatients` discharge, this study aimed to investigate reasons for long-term stay of patients admitted in general hospitals. A total of 135 patients, who were staying at 7 general hospitals in Inchon and Kyinggi-Do for more than 60 days, were surveyed with a self-administered questionnaire between April 3 and April 10, 2000. Medical reasons including incompleteness of necessary care, difficulty in receiving outpatient-based care, and being under physical therapy were the most significant factors associated with long-term stay, followed by the lack of familial resources to take care of patients after discharge. Financial problems such as inability to pay for hospital bills were not significant factors influencing long-term stay. Regression analyses were conducted for medical reasons, familial resources, and financial problems, respectively. It was shown that receiving physical therapy and the number of admission in the past were significant predictors for medical reasons. The lack of familial resources as a reason for long-term stay had a positive relationship with the degree of need for aid in daily living. It may be recommended for the hospitals to cope with administrative problems due to the patients` long-term stay, considering the reasons of it, and their characteristics. And also, institutional efforts like vitalizing the home care service systems by hospitals as the continuing care after discharge should be needed.
Clinical Features of Early and Late Postoperative Hypothyroidism After Lobectomy
Park, Suyeon,Jeon, Min Ji,Song, Eyun,Oh, Hye-Seon,Kim, Mijin,Kwon, Hyemi,Kim, Tae Yong,Hong, Suck Joon,Shong, Young Kee,Kim, Won Bae,Sung, Tae-Yon,Kim, Won Gu The Endocrine Society 2017 The Journal of clinical endocrinology & metabolism Vol.102 No.4
방사성요드 치료를 받은 그레이브스병 환자에서 예후와 연관된 인자
박혜영,강문호,김홍규,이성광,정연실,공희상 대한내분비학회 1999 Endocrinology and metabolism Vol.14 No.4
Background: Prediction of therapeutic response to radioactive iodine (RAI) in Graves disease is poorly understood. Although thyrotropin binding inhibitor immunoglobulin (TBII) level is a strong index for relapse after antithyroid drug treatment, conflicting results are described regarding its prognostic significance in Graves disease treated with RAI. This study is to evaluate possible prognostic factors including TBII wbich affect the outcome of RAI therapy in Graves disease. Methods: Two hundred and one patients with Graves disease who were followed for over 12 months after RAI treatment were studied retrospectively. The subjects were divided into hypothyroid, euthyroid and hyperthyroid groups, based on the thyroid function evaluated at 12 months after RAI therapy. We evaluated the association of clinical parameters including patients age, goiter size, degree of hyperthyroidism and TBII index with outcome of RAI treatment. Results: In Graves disease, response rate to RAI was 70.1% (hypothyroid 22.4% and euthyroid 47.7%) until 12th month. The mean age of hypothyroid group was 40±11 years, significantly older than that other groups (euthyroid: 33±12, hyperthyroid: 35±13, p$lt;0.05). Initial level of thyroid function, duration of antithyroid drug treatment prior to RAI, goiter size and dosage of RAI were not significantly different between the groups. There were 61 patients who had both TBII tests before and after RAI. Twelve had negative TBII and 49 had positive TBII before RAI admini-stration. The rate of unremitted hyperthyroidism after RAI therapy was significantly lower in patients with negative TBII than in those with positive TBII prior to RAI treatment( 0% versus 46.9%, p$lt;0.05). Conclusion: Graves patients with positive TBII prior to RAI therapy were associated with lower therapeutic response to RAI than those with negatve TBII. And old age was associated with the development of early hypothyroidism after RAI therapy. These results suggest these factors be also considered in the treatment of Graves diseaseth RAI (J Kor Soc Endocrinol 14:679-687, 1999).
Park, Jeongseon,Joo, Heeyoung,Noh, Minwoo,Namkoong, Yon,Lee, Seonju,Jung, Kyung Hwa,Ahn, Hye Ryun,Kim, Seulah,Lee, Jong-Chan,Yoon, Jae Hoon,Lee, Yan The Royal Society of Chemistry 2018 Journal of materials chemistry. A, Materials for e Vol.6 No.3
<P>A variety of UCST-type thermoresponsive ammonium iodide salts is systematically designed and synthesised with desired aqueous solubility, phase-transition temperature, osmolality change, phase-transition concentration range, stability, and toxicity by controlling the ionic interactions, hydrophobicity, and symmetry of the salt structure. Suitable draw solutes can be selected based on the characteristics of the ammonium iodide salts as well as the feed solutions for feasible forward osmosis (FO)-based water purification. In this research, highly concentrated wastewater from a flue gas desulfuriser (FGD), with osmotic pressure three times higher than seawater, is targeted for purification by FO using the draw solutes. Two ammonium iodide salts (HM8I and HM10I) show a remarkable water flux from the wastewater samples and significantly lower salt leakage compared to conventional draw solutes. The osmolality of the phase-separated draw solution drops to less than one tenth of that of the initial feed solution, and reverse osmosis or nanofiltration can be applied to the solution with much lower external pressure for the final purification to produce fresh water. This systematic approach to the design and selection of suitable draw solutes can be an effective strategy for future practical FO-based wastewater treatment and seawater desalination.</P>