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      • KCI등재후보

        정상면역을 가진 환자에서 발생한 복부대동맥의 진균 감염성동맥류 1예

        이호영,김태형,추은주,전민혁,이은정,정은정,전성란,박의주,염욱,장원호,황정화,김동훈,김동원 대한감염학회 2008 감염과 화학요법 Vol.40 No.3

        감염성동맥류는 드물지만, 치명적인 질환이다. 진성 진균성 감염성동맥류는 더 드물게 발생한다. 진균감염은 사망률과 이환율이 매우 높다. 그러나 증상이 비특이적이고 일반적인 진단방법으로는 민감하게 진단이 되지 않기 때문에 종종 진단이 어렵다. 저자들은 면역이 정상이고 다른 위험인자가 없는 환자에서 복부대동맥에 발생한 진균성 감염성동맥류를 경험하여 이를 보고한다. 컴퓨터 단층촬영과 혈관 수술에 기초하여 진단하였으며, 수술 후 조직배양에서 균이 동정되지는 않았으나 절제한 혈관조직에서 칸디다 감염을 시사하는 발아가 있는 효모균이 관찰되었다. 한국에서 1988년에서 2007년까지 복부에 발생한 감염성동맥류 17증례를 고찰하였을 때 진성 진균성 감염성동맥류는 없었으며, 저자들이 경험한 것이 복부에서 발생한 진균감염성 동맥류로는 첫 증례이다. Infected aneurysms are uncommon, frequently fatal lesions. "True" fungus-infected aneurysms are even rarer. Fungal infections have high morbidity and mortality. However, diagnosis is frequently difficult, since the symptoms are non-specific and standard diagnostic procedures are often insensitive. We experienced a patient with persistent fever and negative blood cultures. The patient was immunocompetent and had no risk factors, and was diagnosed with a fungus-infected aneurysm based on computed tomography and vascular surgery. The vascular tissue revealed some narrow-based budding yeast within the thrombus, suggesting Candida infection. Seventeen cases of infected aneurysm of the abdomen were reported in Korea from 1988 to 2007, although none were "true" fungus-infected aneurysms, making this the first fungus-infected aneurysm of the abdomen in Korea. Prompt diagnostic procedures and aggressive treatment modalities are necessary for patients with occult infection and negative blood cultures, regardless of their immunocompetence, because of the high morbidity and mortality of this condition.

      • KCI등재
      • 치근면에 도포된 Tetracycline의 유리양상에 관한 연구

        정은희,정현주 전남대학교 치과대학 1989 전남치대논문집 Vol.1 No.2

        This study was performed to observe the desorption pattern of tetracycline-HCI topically applied to root surface. Periodontally diseased human teeth were extracted and root planed thoroughly. Dentin slabs were prepared from roots and applied with 50 ㎎/㎖ and 100 ㎎/㎖ tetracycline-HCI solution for 5 minutes and immersed in 1㎖ of distilled water. The aliquot of distilled water was exchanged and assayed for tetracycline by measuring the absorption peak at 276nm on UV Spectrophotometer every 12 hours. For in vivo study, two individuals diagnosed as moderate to severe periodontitis were selected and 50 ㎎/㎖ and 100 ㎎/㎖ solution of tetracycline-HCI were applied topically to root surfaces during flap surgery. Gingival fluid was sampled from 10 sites per patient using paper strip at 1, 2, 4, 8, 24, 32, 48, 56, 72, 96, 120 and 144 hours. The absorbed paper strips were placed on Mueller-Hinton agar plate containing Bacillus cereus and incubated aerobically in 37℃, 12 hrs and the inhibition diameters were measured. The results were as follows : 1. In vitro study From dentin slabs treated with 50 ㎎/㎖ and 100 ㎎/㎖ tetracycline solution, concentration of tetracycline released in distilled water was 7.32 ㎍/㎖ and 6.18 ㎍/㎖ at 48 hours and 1.3 ㎍/㎖ and 1.42 ㎍/㎖ at 7 days, respectively. The amount of desorption of tetracycline was 5.04 ㎍/㎣ and 5.49 ㎍/㎣ respectively. 2. In vivo study The concentration of tetracycline in gingival fluid was 5.79 ㎍/㎖ and 6.54 ㎍/㎖ at 4 days in 50㎎/㎖ and 100㎎/㎖ tetracycline treated sites respectively. In two sites of 50 ㎎/㎖ tetracycline treated area and three sites of 100 ㎎/㎖ tetracycline treated area, 4 ㎍/㎖ of tetracycline was desorbed still at 6 days. This study indicates that the topical application of tetracycline-HCI results in substantial binding to tooth substance and slow release of effective tetracycline concentration for several days, and the effects of tetracycline may contribute to new attachment of connective tissue.

      • 바이오 디젤유로서 미강유의 분무개선에 관한 연구

        주은선,정석용 慶尙大學校生産技術硏究所 1994 生産技術硏究所論文集 Vol.10 No.-

        This paper is focused on the propriety examination and application plan as a substiution fuel in the rece-bran oil which is obtained as by-product when the rice is milled. Compared with the light-oil, the rice-bran oil has high viscosity, and causes erosion of nozzle, clogging phenomenon. So, in order to solve these problems, the ultrasonic oscillator device has been used and the design of horn was performed, on the basis of physical experimental data of the rice-bran oil. The purpose of the paper is to construct the optimal fuel-injection system using rice-bran oil, therefore it has been performed the experiment to improve the characteristics of an atomization by adding ultrasonic energy on spraying fuel. The sauter mean diameter(SMD) and distribution of spary was measured by using the magnesium oxide method and the immersion one.

      • 옥타데케인 마이크로캡슐 슬러리를 이용한 관내대류 열전달에 관한 연구

        정동주,최은수 명지대학교 대학원 1998 대학원논문집 Vol.2 No.-

        As a method of heat transfer enhancement, octadecane was micro-encapsulated and added to water. The capsule wall was made of melamin. Its outer diameter was about 10㎛. 75% of the capsule mass was octadecane. The slurry did not show non-newtonian viscosity when the fraction of the capsules in the slurry was under 20%. Even though the pressure drop did not become high, but effective heat capacity was measured high. Nusselt number measured in the heating test section was similar with expected value when the octadecane was not melted, but higher than expected value when the octadecane was melted.

      • 방사선 치료를 받는 암 환자들의 사회적 지지와 삶의 질과의 관계

        정주희,류소연,윤혜은,남택근,오윤경,안현옥,박계남,이영선 朝鮮大學校 附設 醫學硏究所 2002 The Medical Journal of Chosun University Vol.27 No.2

        Objective : This study was performed to investigate the relationship between social support and quality of life among cancer patients receiving radiation therapy. Matehals and Methods : The data were collected from 98 patients, who were receiving radiation therapy at two university hospitals located in GwangUJu, used by structured questionnaire. For statistical analyses of the association between quality of life and various characteristics, data were analyzed using t-test, ANOVA, Pearson 's correlation, and multiple regression analysis. Results: 1. There were 56(57.1%) males and 42(42.9%) females. Age ranged from 21 to 82 years. The primary sites of cancer were gastrointestinal tract (24.5%), lung (23.5%), breast (21.4%), and head and neck (11.2%) in order. 2. The mean scores of social, family, and medical support were 4.30 0.58, 4.49 0.78, 4.11 0.65, respectively. The score of quality of life was 5.83 1.63 (range: 1.95 ~ 9.05). 3. An analysis of the association between several factors of patients and quality of life showed that the statistically significant factors were age, the presence of distant metastasis, family support, medical support and social support. 4. As a result of the multiple regression analysis, only social support was significant (β=0.932, P=0.02) with quality of life, but age and presence of distant metastasis were not significant. Conclusion : This suggests that quality of life in cancer patients could be improved by strengthening the social support which consists of family and medical support. Further study would be necessary to evaluate separately several aspects of quality of life among cancer patients.

      • 미립피복 로릭산 슬러리의 열물성치 및 겉보기 점도 특성에 관한 연구

        鄭東柱,崔恩洙 明知大學校 産業技術硏究所 2005 産業技術硏究所論文集 Vol.24 No.-

        The objective of the present study is to reveal the thermal and flow characteristics of MC lauric acid slurry. The thermal characteristics of pure lauric acid and MC lauric acid were tested by a differential scanning calorimeter. The cooling curve of MC lauric acid showed a double curve, while that of the lauric acid showed a single curve. The effects of encapsulation was measured and explained. The flow characteristics of MC lauric acid slurry were tested by a capillary tube viscometer and a rotating cylindrical viscometer. The slurry showed shear thinning behavior, when the fraction of MC lauric acid is over 5%.

      • 상부소환관협착에 대한 Savary-Gilliard Dilatation의 치료효과와 안전성에 관한 관찰

        정현용,육은주,임의혁,김병호,성자원,이기천,허승식,이헌영,김영건 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2

        For the patient with stenosis of upper digestive tract caused by either benign or malignant process, esophageal dilatation is an important therapeutic modality. We reviewed retrospectively 39 cases treated by Savary-Gilliard dilatation for upper digestive tract stenosis, and results were follows : (1) Dysphagia was improved in 95% of the patients. (2) Eight patients(20%) sufferd perforation, five of them were managed with conservative medical measures, others were managed operatively. (3) In the cases with benign stenosis dysphagia was not noticed for 8.8 months, but with malignant stenosis dysphagia was reappeared after 2.8 months despite concomitant chemoradiotherapy. In conclusion, Savary-Gilliard dilatation was an effective measure for symptome due to upper digestive tract stenosis, but more careful attention for perforation should be necessitated. Also another therapeutic modality for treatment of malignant stenosis was inevitable.

      • KCI등재

        제2형 근관의 확대에 따른 최종근관장파일 크기의 비교

        정은주,이동균,백신영,황호길 大韓齒科保存學會 2008 Restorative Dentistry & Endodontics Vol.33 No.5

        제2형의 근관형태를 갖는 치아에서 각각의 근관을 모두 근관장까지 확대한 경우,여러 확대기구에 따른 최종근관장파일의 크기를 상호 비교하여 얼마나 많은 변화가 있었는지를 분석하고자 치근 우식이 없고 치근단공 형성이 완료되었으며 2개의 근관 입구에서 시작하여 하나의 치근단공을 갖는 제 2형의 근관형태를 보이는 상악 소구치,상악 대구치의 근심협측 치근 및 하악 대구치의 근심 치근을 선택하여 확대기구에 따라 KF 군, PT 군,HS 군, K3 군으로 분류하고 치경부 조기 확대를 시행하였다. 초기근관장파일이 15번 크기인 지아를 각 군당 20개씩 무작위로 선택하였고,모든 근관을 각 군에 해당되는 30번 크기의 파일까지 제조회사의 지시에 따라 확대를 시행한 후,촉감과 universal testing machine을 이용하여 최종근관장파일의 크기를 결정하였다. 각 군의 최종근관장파일의 크기와 제거 시 요구되는 힘의 크기에 대한 유의성 검증은 one-way ANOVA를 이용하여 비교 분석하였으며,사후검정은 Tukey HSD test를 이용하여 0.05의 유의수준에서 분석하였다. 본 연구의 결과 제2형의 근관형태를 갖는 치아의 근관확대 시,모든 근관을 각각의 근관장으로 확대하는 방법은 확대에 마지막으로 이용된 기구의 크기보다 한,두 단계 정도 증가된 최종근관장파일을 나타냈다. 그러므로 제2형 근관형태를 나타내는 치아의 근관치료 시 임상가들은 근관충전에 앞서 치근단 받침을 다시 확인하고 형성하는 과정이 필요하리라 사료된다. Type II root canal was defined that two canals leave the chamber and merge to form a single canal at short of the apex. The aim of this study was to analyse the master apical file (MAF) size according to various instrumentation techniques in the type II root canal when each canal was enlarged to working length. Eighty mesial roots of molar with ISO #15 initial apical file (IAF) size in type II root canals were randomly divided into four experimental groups with 20 teeth each. According to enlarging instruments, four groups are: K-FLEXOFILE^(?) (KF), engine-driven Ni-Ti PRoT_(APER)^(?)(PT), HERO Shaper^(?)(HS), K³™ (K3). All canals were enlarged to each working length with ISO #30 size: #30 in KF, F3 in PT, .04/30 in HS, and .06/30 in K3. The master apical file (MAF) size was confirmed by tactile sensation and universal testing machine (EZ test, Shimadzu Co., Kyoto, Japan). The mean MAF size was statistically compared using one-way ANOVA and Tukey HSD test at the 0.05 probability level. These results show that the MAF size was appeared one or two sizes larger than the final enlarging instrument when all canal in type II configuration were enlarged to each working length. Therefore, the clinician have to confirm the apical stop once more after instrumentation of type II root canal.

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