Development of label-free electrochemical lactose biosensor based on graphene/poly(1,5-diaminonaphthalene) film

Binh Hai Nguyen,Binh Thanh Nguyen,Hanh Van Vu,Chuc Van Nguyen,Dzung Tuan Nguyen,Loc Thai Nguyen,Thu Thi Vu,Lam Dai Tran 한국물리학회 2016 Current Applied Physics Vol.16 No.2

In this work, a lactose biosensor was developed by co-immobilizing b-galactosidase (b-Gal) and glucose oxidase (GOx) on microelectrodes pre-modified with Pt/graphene/P(1,5-DAN) for estimation of lactose in dairy products to prevent lactose intolerance. The Pt microelectrode was modified with graphene and 1,5-polydiaminonaphthalene film. Graphene was synthesized by chemical vapor deposition on copper tape and manually transferred to the electrode surface. Polymeric P(1,5-DAN) was grafted on top of the graphene film by electropolymerization. Modified surface of the electrode was characterized by Raman spectra analysis, FE-SEM, AFM and cyclic voltammetry. The results indicated that deposition graphene film on electrode surface induced considerable enhancement in current signal, over 20 times as high as the uncoated electrode surface. The developed sensor was successfully used to determine lactose in model samples with sensitivity, correlation coefficient (R2) and limit of detection (LOD) estimated to be 1.33 mA/(mgml1), 0.995 and 1.3 mg/ml, respectively. The combined graphene and conductive P(1,5-DAN) could serve as a novel sensing platform on electrochemical sensors with superior sensitivity.

Assessment of the Quality of Non-Financial Information Disclosure: Empirical Evidence from Listed Companies in Vietnam

Binh Thi Hai LE,Nhat Quoc NGUYEN,Cong Van NGUYEN 한국유통과학회 2022 The Journal of Asian Finance, Economics and Busine Vol.9 No.5

The purpose of this research is to evaluate the quality of non-financial information disclosure by companies listed on the Vietnamese stock exchange. In 2019, 140 annual reports from 140 companies listed on the Vietnam Stock Exchange were included in the research sample. The remaining 134 reports were eligible study after removing those that lacked essential data. Using the statistical software SPSS version 25 and Excel office software, the study has selected the data processing method and the disproportionate disclosure index method to evaluate the quality of non-financial information disclosure of companies. The findings of the study demonstrate that companies listed on the Vietnam stock exchange are particularly interested in giving non-financial information to financial statement consumers as required by law, although the level of disclosure is still inadequate. The findings also illustrate the varying levels of non-financial information disclosure by category of information, as well as substantial disparities between them (general information about the company, environmental and social information, corporate governance information, etc.). The findings of the study show that the majority of Vietnam’s publicly traded enterprises are less interested in reporting environmental information.

Facile synthesis of multifunctional Ag/Fe3O4-CS nanocomposites for antibacterial and hyperthermic applications

Ngoan Thi Nguyen,Dai Lam Tran,Duc Cuong Nguyen,Thai Loc Nguyen,Thi Cham Ba,Binh Hai Nguyen,Thi Duong Ba,Nam Hong Pham,Dzung Tuan Nguyen,Thai Hoa Tran,Gia Dien Pham 한국물리학회 2015 Current Applied Physics Vol.15 No.11

Nanocomposites containing two or more functional constituents are attractive candidates for advanced nanomaterials. In this study, multifunctional Ag/Fe3O4-CS nanocomposites were successfully prepared, using chitosan as a stabilizing and cross-linking agent. The as-synthesized nanocomposites were characterized by Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), X-ray diffraction (XRD), Energy-dispersive X-ray spectroscopy (EDS), UVevisible spectrophotometer (UVeVis) and vibrating sample magnetometer (VSM). The results demonstrated that Ag/Fe3O4-CS composite nanoparticles (NPs) were composed of parent components, Fe3O4 and Ag NPs, which were uniformly dispersed in the chitosan matrix. The hybrid NPs exhibited strong antibacterial property against Pseudomonas aeruginosa. With high magnetization value (67 emu/g), the synthesized Ag/Fe3O4-CS composite can be easily separated or recycled in potential biomedical applications. Furthermore, the results showed that the multicomponent hybrid nanostructures appeared to be the promising material for local hyperthermia, which can be used as thermoseeds for localized hyperthermia treatment of cancers.

Economic Cooperation in the Greater Mekong Sub-Region

Binh Hai Le,Dang Quyen Nguyen,Kieu Trang Vu,Hiep Ngoc Luu,Farhad Taghizadeh-Hesary 세종대학교 경제통합연구소 2020 Journal of Economic Integration Vol.35 No.2

This paper investigates the impact of regional economic cooperation between Vietnam and its partners during the 2000-2015 period, focusing on the Greater Mekong Sub-region (GMS). Overall, the GMS represents a significant portion of Vietnam’s trade portfolio. China is the dominant trading partner in the GMS, exhibiting strong influence over Vietnam’s trade, especially its imports. However, using the gravity model of trade, we find that Vietnam has not benefited from GMS cooperation, as exemplified by its significant trade deficit, particularly with China. We further find that human capital enhancement and financial development are key factors to facilitate Vietnam’s trade, and mitigate its trade deficit with other GMS member countries. To this end, this study provides some important policy implications for the Vietnamese government as well as policymakers in other countries, when trading with larger partners in the context of regional economic cooperation.

Argyreia gyrobracteata Traiperm & Chitchak (Convolvulaceae): A new record to the flora of Vietnam

Binh Duc TRAN,Bach The TRAN,Do Van Hai,Quang Hong BUI,Son Hoang DOAN,Han Ngoc LE,Thuy Thu NGUYEN,엄상미 한국식물분류학회 2020 식물 분류학회지 Vol.50 No.3

Argyreia gyrobracteata Traiperm & Chitchak (Convolvulaceae) is newly recorded in Vietnam. It is similar to A. mekongensis Gagnep & Courch in having a white campanulate corolla but differs from that species by having whitish surface of the abaxial leaf, narrowly lanceolate or linear-oblong, curly, rolled up the bract with a longer length of the petiole and a shorter pedicel. It was previously known only in Thailand, but was recently found in Lam Dong Province, Vietnam, for the first time. The present study provides a detailed description, colorful photos and the distribution of the species. Furthermore, a comparison of the diagnostic characters between this species and a related species in Vietnam, A. mekongensis Gagnep & Courch, is provided.

First Report on Multidrug-Resistant Methicillin-Resistant Staphylococcus aureus Isolates in Children Admitted to Tertiary Hospitals in Vietnam

( Nguyen Thai Son ),( Vu Thi Thu Huong ),( Vu Thi Kim Lien ),( Do Thi Quynh Nga ),( Tran Thi Hai Au ),( Tang Thi Nga ),( Le Nguyen Minh Hoa ),( Tran Quang Binh ) 한국미생물생명공학회(구 한국산업미생물학회) 2019 Journal of microbiology and biotechnology Vol.29 No.9

The extensive distribution of multidrug-resistant (MDR) methicillin-resistant Staphylococcus aureus (MRSA) poses a threat to healthcare worldwide. This study aimed to investigate the MDR and molecular patterns of MRSA isolates in children admitted to the two biggest tertiary care pediatric hospitals in northern and southern Vietnam. A total of 168 MRSA strains were collected to determine antibiotic susceptibility by minimum inhibitory concentration tests. Antibiotic-resistant genes, pulsed-field gel electrophoresis, staphylococcal cassette chromosome mec (SCCmec) typing, and multilocus sequence typing were used for the molecular characterization of MRSA. Among the total strains, the MDR rate (51.8%) was significantly higher in the northern hospital than in the southern hospital (73% vs. 39%, p < 0.0001). The MDR-MRSA with the highest rates were “ciprofloxacin-erythromycin-gentamicin-tetracyclines” (35.6%), followed by “erythromycin-tetracycline-chloramphenicol” (24.1%), and “ciprofloxacin-erythromycin-gentamicin” (19.5%), showing an accumulative total of 79.3%. The most susceptible antibiotics were rifampicin (100%) and vancomycin (100%), followed by doxycycline (94.0%), meropenem (78.0%), and cefotaxime (75.0%). The SCCmecII strains showed greater resistance to gentamicin, ciprofloxacin, tetracycline, meropenem and cephalosporins compared with the other strains. The SCCmecII strains exhibited the highest rate in the tested genes (aacA/aphD: 55.2%, ermA/B/C: 89.7%, and tetK/M: 82.8%). ST5-SCCmecII was the predominant clone in the northern hospital, whereas SCCmecIVa was more pronounced in the southern hospital. In conclusion, our results raised concerns about the predominant MDR-MRSA strains in the pediatric hospitals in Vietnam. The north-south difference in the antibiotic resistance patterns and genetic structure of MRSA suggests different MRSA origins and various uses of antimicrobial agents between the two regions.

Useful Unlabeled Data Selection Using Cuckoo Search Algorithm for SemiBoost Learning

Trung Hai Nguyen(누엔충하이),Thanh-Binh Le(레탕빈),Sang-Woon Kim(김상운) 대한전자공학회 2016 대한전자공학회 학술대회 Vol.2016 No.6

Carbon coated MFe2O4 (M=Fe, Co, Ni) magnetite nanoparticles: A smart adsorbent for direct yellow and moderacid red dyes

Hoang Vinh Tran,Hai Van Nguyen,Doanh Viet Vu,Thu Dieu Le,Binh Thanh Nguyen,Dang Hai Le 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.2

We report here a simple approach for synthesis of carbon coated magnetite (C@MFe2O4, M=Co, Ni, Fe) with shell@core nanostructured composites that we used as magnetic-nanosorbents for direct yellow (DYG) and moderacid red (RS) as pollutant textile dyes removal via an adsorption process. The synthesized C@MFe2O4 was characterized by TEM, SEM, EDX, XRD, FT-IR and VSM techniques. TEM results indicated that C@MFe2O4 nanocomposites have 20-30 nm of MFe2O4 nanoparticle core and 2-3 nm in thickness of the amorphous carbon shell. The synthesized C@MFe2O4 nanocomposites have the zero point charge (pHZPC) at 5.5, which suggests that DYG and RS, anionic dyes can be adsorbed onto the C@MFe2O4 nanosorbents in the acidic medium. Adsorption of DYG and RS onto magnetic nanosorbents was optimized and adsorption thermodynamic parameters were evaluated, clearly indicating that the adsorption of RS onto synthesized magnetic-nanosorbents was facile more than that DYG. The adsorption isotherm data showed that the adsorption processes of DYG and RS onto Fe3O4 or C@MFe2O4 nanosorbents are more suitable for the Langmuir model than Freundlich model. The maximum adsorption capacity (qmax) of DYG dye onto Fe3O4, C@Fe3O4 and C@CoFe2O4 adsorbents was 14.641, 36.232 and 7.85mg g1, respectively; meanwhile, these values were 41.152, 61.728 and 39.683mg g1 for RS dye. These obtained data indicate that the developed Fe3O4, C@Fe3O4 and C@CoFe2O4 nanoparticles can be used as recoverable and recyclable adsorbents for not only organic pigments adsorption but also for heavy metal ion removal or protein extraction as well.

Environmental Chemical-Dioxin Impacts on Biological Systems: A Review

Thuy Thi Bich Vo,Binh Thi Nguyen Le,Hai Van Nong,Hyun Yang,Eui-Bae Jeung 韓國受精卵移植學會 2013 한국동물생명공학회지 Vol.28 No.2

Worldwide there is concern about the continuing release of a broad range of environmental endocrine disrupting chemicals, including polychlorinated biphenyls, dioxins, phthalates, polybrominated diphenyl ethers (PBDEs), and other halogenated organochlorines persistent organic pollutants (POPs) into the environment. They are condemned for health adverse effects such as cancer, reproductive defects, neurobehavioral abnormalities, endocrine and immunological toxicity. These effects can be elicited via a number of mechanisms among others include disruption of endocrine system, oxidation stress and epigenetic. However, most of the mechanisms are not clear, thus several number of studies are ongoing trying to elucidate them in order to protect the public by reducing these adverse effects. In this review, we briefly limited review the process, the impacts, and the potential mechanisms of dioxin/dioxin like compound, particularly, their possible roles in adverse developmental and reproductive processes, diseases, and gene expression and associated molecular pathways in cells.

Self-antibacterial chitosan/Aloe barbadensis Miller hydrogels releasing nitrite for biomedical applications

Thai Thanh Hoang Thi,Binh D.T. Trinh,Phuong Le Thi,Dieu Linh Tran,박기동,Dai Hai Nguyen 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.103 No.-

Because of the toxic glutaraldehyde, the chitosan-glutaraldehyde hydrogels are seriously limited inbiomedical applications. In this study, exploiting bioactive compounds of Aloe barbadensis Miller, the chitosan/Aloe barbadensis Miller-glutaraldehyde (CS/AV-GDA) hydrogels were fabricated with 4-fold lowerglutaraldehyde concentration without compromising hydrogel characteristics. The gelation time wascontrolled from a few seconds to several hours. The elastic modulus was varied from 483 to 99940 Pa. The CS/AV-GDA hydrogels could release the natural nitrite amount from 24.0 to 89.6 lM within the firsthour for antibacterial activity, then continuously deliver a few lM every next hour for cell activities. Theantibacterial test against Escherichia coli and Staphylococcus aureus revealed that the CS/AV-GDA hydrogelscould kill the planktonic bacteria 5-fold more highly than control and prevent bacteria attachmenton hydrogel surface effectively. Although the CS/AV-GDA hydrogels consumed only 0.25% glutaraldehydeconcentration, their antibacterial capacities were comparable to chitosan-only hydrogels with 2% glutaraldehyde. For cytotoxicity tests, the CS/AV-GDA hydrogels using 0.25% glutaraldehyde concentrationinduce the human dermal fibroblasts proliferation significantly. All CS/AV-GDA hydrogels with glutaraldehydecrosslinker less than 1% showed non-cytotoxicity. As a result, the new CS/AV-GDA hydrogelsmight become an attractive candidate for medicine regeneration and tissue engineering.