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        Preparation and characterization of rutile phase TiO2 nanoparticles and their cytocompatibility with oral cancer cells

        Vu Phuong Dong,Nguyen Thi Kieu Trang,Hoon Yoo 대한구강생물학회 2019 International Journal of Oral Biology Vol.44 No.3

        In the present study, rutile phase titanium dioxide nanoparticles (R-TiO 2 NPs) were prepared by hydrolysis of titanium tetrachloride in an aqueous solution followed by calcination at 900℃. The composition of R-TiO 2 NPs was determined by the analysis of X-ray diffraction data, and the characteristic features of R-TiO 2 NPs such as the surface functional group, particle size, shape, surface topography, and morphological behavior were analyzed by Fourier-transform infrared spectroscopy, scanning electron microscopy and energy dispersive X-ray spectroscopy, transmission electron microscopy, dynamic light scattering, and zeta potential measurements. The average size of the prepared R-TiO2 NPs was 76 nm, the surface area was 19 m 2 /g, zeta potential was −20.8 mV, and average hydrodynamic diameter in dimethyl sulfoxide (DMSO)–H 2 O solution was 550 nm. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and morphological observations revealed that R-TiO 2 NPs were cytocompatible with oral cancer cells, with no inhibition of cell growth and proliferation. This suggests the efficacy of R-TiO 2 NPs for the aesthetic white pigmentation of teeth.

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        Economic Cooperation in the Greater Mekong Sub-Region

        Binh Hai Le,Dang Quyen Nguyen,Kieu Trang Vu,Hiep Ngoc Luu,Farhad Taghizadeh-Hesary 세종대학교 경제통합연구소 2020 Journal of Economic Integration Vol.35 No.2

        This paper investigates the impact of regional economic cooperation between Vietnam and its partners during the 2000-2015 period, focusing on the Greater Mekong Sub-region (GMS). Overall, the GMS represents a significant portion of Vietnam’s trade portfolio. China is the dominant trading partner in the GMS, exhibiting strong influence over Vietnam’s trade, especially its imports. However, using the gravity model of trade, we find that Vietnam has not benefited from GMS cooperation, as exemplified by its significant trade deficit, particularly with China. We further find that human capital enhancement and financial development are key factors to facilitate Vietnam’s trade, and mitigate its trade deficit with other GMS member countries. To this end, this study provides some important policy implications for the Vietnamese government as well as policymakers in other countries, when trading with larger partners in the context of regional economic cooperation.

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