신라 중고기골제(中古期骨制)의 성립과 운영

박수진 ( Soo Jin Park ) 수선사학회 2011 史林 Vol.0 No.39

The Golpum system was the unique form of the status system in the Silla dynasty in Korea. It was a typical ancient Korean society`s status system which has been investigated field in the academia. In particular, a kinship system, which is composed of Seong-gol and Jin-gol, is the most hottest issue in the Korean academic circles. However, there is a no point of agreement whether Seong-gol was the reality or not, and concerning about its management and times. This research has a purpose to investigate how the status system established and guaranteed in the society. The Buddism has attracted public attention as a theoretical basis of the status system. The Samkuksagi (The chronics of the three nations) described the Buddism as a state religion while it did not focus on the myths about the Buddism. We assume that the Buddism was the meaningful political controller in the Silla dynasty. Seong-gol was regarded as the royal familiy, and it was available when the King had the superiority over the nobility. The Kings of Sylla dynasty had been called the Great King with a qualifier ``saint`` when the Buddism instituted a state religion. It means that Seong-gol (the saunt family) was established based on the Buddism. Jin-gol also entered a field of history similar times to Seong-gol, and both two terminologies was established the same period in terms of the Buddism terminology. Seong-gol guaranteed a royal family`s prestige through the change of ennoble system Galmun King and the use of the Great King title. The King`s brother, who were Seong-gol, secured the superiority over the nobility by getting the title of ennoblement. The Kings also solidified their status through the ennoble system, and they monopolized political power because the kings restrained the right of succession only kings heirs. Jin-gol also guaranteed their political prestige after established Daedeung. The House of Lords in Silla dynasty limited the qualification only who had the title of Daedeung. Jin-gol class took the reins of the nobility through only Jin-gol getting the title of Daedeung.

비병원성 야생효모로부터 알칼리성 단백질분해효소 생산

문정수, 박경서, 공유리, 김수진, 이종수 배재대학교 자연과학연구소 2022 自然科學論文集 Vol.33 No.1

Cellulase 생산 야생효모의 선별 및 세포외 Cellulase 생산

문정수, 박경서, 김혜원, 김수진, 이종수 배재대학교 자연과학연구소 2016 自然科學論文集 Vol.33 No.1

Differential Manifestation of Ocular Phenotypes in TALEN-mediated p19arf Knockout FVB/N and C57BL/6J mouse lines

Jin‑Sung Park,Joo‑Il Kim,Hyun‑Jin Lim,Soo‑Kyung Ryu,Euna Kwon,Kang‑Min Han,Ki‑Taek Nam,Han‑Woong Lee,Byeong‑Cheol Kang 한국유전학회 2020 Genes & Genomics Vol.42 No.9

Background p19arf, primarily known as a tumor suppressor, has also been reported to play an essential role in normal development of mouse eyes. Consistently, lack of p19arf has been associated with ocular defects, but the mixed background of the knockout (KO) mouse strain used raised a concern on the accuracy of the phenotypes observed in association with the targeted gene due to genetic heterogeneity. Object We carried out a study to investigate into the efect of genetic background on the manifestation of p19arf KO associated phenotypes. Methods We characterized the phenotypes of novel p19arf KO mouse lines generated in FVB/N and C57BL/6J using a transcription activator-like efector nuclease (TALEN) system in comparison to the reported phenotypes of three other p19arf-defcient mouse lines generated using homologous recombination. Results Ninety-fve percent of FVB/N-p19arf KO mice showed ocular opacity from week 4 after birth which worsened rapidly until week 6, while such abnormality was absent in C57BL/6J-p19arf KO mice up to the age of 26 weeks. Histopathological analysis revealed retrolental masses and dysplasia in the retinal layer in FVB/N-p19arf KO mice from week 4. Besides these, both strains developed normally from birth to week 26 without increased tumorigenesis except for a subcutaneous tumor found in a C57BL/6J-p19arf KO mouse. Conclusion Our fndings demonstrated surprisingly variable manifestation of p19arf-linked phenotypes between FVB/N and C57BL/6J mice, and furthermore between our mouse lines and the established lines, indicating a critical impact of genetic background on functional study of genes using gene targeting strategies in mice.

Conceptual Study for Tissue-Regenerative Biodegradable Magnesium Implant Integrated with Nitric Oxide-Releasing Nanofi bers

Jin‑Kyung Jeon,Hyunseon Seo,Jimin Park,Soo Ji Son,Yeong Rim Kim,Eun Shil Kim,Jong Woong Park,Woong‑Gyo Jung,Hojeong Jeon,Yu‑Chan Kim,Hyun‑Kwang Seok,Jae Ho Shin,Myoung‑Ryul Ok 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.4

The excessive initial corrosion rate of Mg is a critical limitation in the clinical application of biodegradable Mg implantsbecause the device loses its fi xation strength before the fractured bone heals. This study suggests a new approach to overcomethis hurdle by accelerating tissue regeneration instead of delaying the implant biodegradation. As angiogenesis is anessential process in early bone regeneration, a Mg implant coated with electrospun nanofi bers containing nitric oxide (NO),which physiologically promotes angiogenesis, is designed. The integrated device enables adjustable amounts of NO to bestored on the NO donor-conjugated nanofi ber coating, stably delivered, and released to the fractured bone tissue near theimplanted sites. An in vitro corrosion test reveals no adverse eff ect of the released NO on the corrosion behavior of the Mgimplant. Simultaneously, the optimal concentration level of NO released from the implant signifi cantly enhances tube networkformation of human umbilical vein endothelial cells without any cytotoxicity problem. This indicates that angiogenesis canbe accelerated by combining NO-releasing nanofi bers with a Mg implant. With its proven feasibility, the proposed approachcould be a novel solution for the initial stability problem of biodegradable Mg implants, leading to successful bone fi xation.

병원에서 사용된 백신양으로 평간한 예방접종 실태

김정수,백용수,정문현,이진수,오경선 대한감염학회 2008 감염과 화학요법 Vol.40 No.3

Background : Studies on immunization in Korea mainly focus to the coverage rates in recipients. The attitudes of health-care providers regarding immunization are rarely evaluated. Therefore, to assess the pattern of vaccine administration by health-care personnel, the vaccine consumption in a university hospital was investigated. Materials and Methods : The vaccine consumption in a university hospital during 2 months (September and October) in 2 years (2002 and 2007) was evaluated. September is representative of months when influenza vaccine is not available, whereas October is representative of months when influenza vaccine is available. These monthly data were summarized by departments and vaccines. Results : Vaccine consumption over the 5-year period increased primarily because of the increased use of the influenza and tetanus-diphtheria (Td) vaccines in adults. In 2007, the most frequently administered vaccine during the influenza season was the influenza vaccine, followed by the Td vaccine. In the same year, the Td vaccine was the most frequently administered vaccine during the non-influenza season. Compared to 2002, there was a marked increase in the use of the hepatitis A virus (7-fo1d), Japanese encephalitis (6-fo1d), and pneumococcal polysaccharide (3-fold) Vaccines in 2007; the Td, meningococcal, and pneumococcal protein-conjugated vaccines were not available in 2002. In adults, pneumococcal vaccination was increasingly prescribed concomitant with the increased influenza vaccination: a similar trend was not observed in children. The use of vaccines in most departments was confined to the influenza vaccine, and the majority of Td vaccine was consumed in the emergency department. As compared to the internal medicine and family medicine departments, fewer vaccines were prescribed by the neurology, surgical, and minor specialty departments, especially in the non-influenza season. Conclusion : Although vaccine consumption increased during the 5-year period, the increase was attributed to the increased consumption of the influenza vaccine. Promotion and education regarding the use of non-influenza vaccines are needed. 배경 : 국내에서 백신 사용은 접종을 받은 사람에서만 조사가 되었고, 예방접종 제공자에서 조사가 적었다. 앞으로 백신 접종률을 높이기 위해서는 접종자에 대한 연구도 있어야 하며, 병원 단위에서 백신 사용 양상을 알기 위해 대학병원에서 백신 사용량을 조사하였다. 재료 및 방법 :2002년과 2007년의 9월과 10월에 약제부에서 사용된 백신 양을 조사하였다. 9월은 인플루엔자 백신이 없는 달을 대표하는 달이고 10월은 인플루엔자 예방 접종이 가능한 달을 대표한 것이다. 월별 백신 소모량을 과별, 백신별로 정리를 하였다. 결과 : 2002년에 비해 2007년에는 백신 사용량이 1.6배 증가했으며, 인플루엔자 백신과 Td의 사용 증가가 주요 이유였다. 인플루엔자 백신 접종 시기에는 인플루엔자 백신 사용량이 제일 많았고, 두 번째 많이 사용되는 백신은 2002년에는 B형 간염 백신이었고 2007년에는 Td였다. 성인에 서는 인플루엔자 백신 사용과 함께 폐렴사슬알균 백신 사용량이 늘었지만 소아에서는 이런 경향이 보이지 않았다. 인플루엔자 백신 접종 시기인 10월에는 소아과에서 사용보다 비소아과에서 백신 사용량이 더 많았다. 과별로 보면 대부분 과에서 인플루엔자 백신이 주로 사용되었고, 응급실에서는 Td만이 사용되었다. 신경과와 재활의학과, 외과계열, 소수과에서 사용이 적었다. 결론 : 예방접종이 5년 사이 증가하였으나 인플루엔자 백신에 국한된 양상을 보였다. 인플루엔자 백신과 파상풍-디프테리아 백신뿐만 아니라 다른 백신에 대한 홍보가 필요하다.

인공와우이식술후 선천성 농아동과 언어습득전 후천성 농아동의 말인지 변화

김수진,김리석,이규식 대불대학교 1999 論文集 Vol.5 No.1

Children with cochlear implants can significantly achieve improvement in speech perception skills as the age at implantation of younger children decreases. The purpose of this study was to examine speech perception abilities over time of childern with prelingually acquired and congenital deafness since cochlear implantation. Nine children with congenital deafness and 6 children with prelingually acquired deafness were implanted with the Nucleus multichannel cochlear prosthesis and them between 1 and 3 years. They ranged in age from 2 years 9 months to 10 years 11 months. The children were evaluated with a battery of speech perception tests with audition alone at pre-implantation and 6 month intervals from initial stimulation. The children with prelingually acquired and congenital deafness received similar benefits from cochlear implant. The speech perception performance of most children improved with experience of the implant. Although large individual differences were observed in speech perception ability, length of implant usage contributes to improved performance.

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

SLAP Ⅱ 병변의 진단을 위한 관절 조영 자기 공명 영상에서 견관절 위치에 따른 비교

이영수,신동배,박수진,김진용,김희상,하두회 대한견.주관절학회 2000 大韓肩.주關節學會誌 Vol.3 No.2

향기요법이 통증을 주소증으로 입원한 환자의 수면장애에 미치는 영향

박수곤 ( Soo Gon Park ),양미성 ( Mi Sung Yang ),김오영 ( Oh Young Kim ),조희근 ( Hee Guen Jo ),최진봉 ( Jin Bong Choi ),김선종 ( Sun Jong Kim ),설재욱 ( Jae Uk Sul ) 한방재활의학과학회 2010 한방재활의학과학회지 Vol.20 No.4

Objectives :The purpose of this study is to investigate the effects of aroma therapy on sleep disorder patients with musculoskeletal pain. Methods :The 44 patients were divided into 2 groups: Experimental group(Exp. group) was treated with aroma therapy and control group was treated except aroma therapy. To evaluate the efficiency of aroma therapy, the Korean sleep scale A(Jin-Joo Oh, Mi-Soon Song, Sin-Mi Kim. 1998) and visual analogue scale(VAS) were applied before treatment and after 5 days treatment. Results :1. The Experimental group has improved statistical significance in sleep disorder score as compare to the control group. 2. The improvement of sleep disorder score of Exp.group has difference according to impression. 3. The improvement of sleep disorder has an effect on pain decrease. Conclusions :Aroma therapy has effects of improvement on sleep disorder with musculoskeletal pain.