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김성민,이종호,김남열,안강민,최원재,최시호,차미주,이주영,황순정,장정원,명훈,최진영,서병무,정필훈,김명진 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.4
Schwann cells(SCs), an important component of the peripheral nervous system, intract with nerous to mutually support growth and replication for the peripheral nerve regentation. Recently, ading SCs to the lumen of guidance channel is widely tried to improve regeneration or to make regeneration possible over otherwise irreparable gaps. however, it is not easy to isolate and multiplicate SCs as much as enough to help the axonal regeneration. For the allogeneic SCs source for tubular nerve guidance, we developed a little bit improved technique of harvesting and multiplicating SCs. by culturing dispersed dorsal root ganglia in specially designed medium with growth factors and serial processing, we repeatedlly generate relatively homogenous SC cultures. Our technique was compared with other methods of literature using immunostaining methods such as GFAP, S100, BDNF and the total SC count assessment at different time interval after primary culture.
Chlorpromazine이 백서 해마에서 전기경련 충격에 의한 MAPK 타이로신 인산화에 미치는 영향
주연호,정성훈,전송희,강웅구,김용식,김상욱,박주배 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.2
Object : In order to examine the interaction mechanisms of electroconvulsive shock(ECS) and antipsychotic drug at the level of molecular biology, we observed the effect of chlorpromazine pre-treatment on the activation of mitogen activated protein kinase(MAPK) induced by electroconvulsive shock(ECS) in rat hippocampus Method : Male Sprague-Dawley rats were divided into 2 groups. To the experimental group chlorpromazine(20㎎/㎏) was given intraperitoneally, and to the control distilled water was given instead. Thirty minutes later, ECS was given and the hippocampus was dissected out 2 minutes thereafter. Immunoblotting with antiphosphotyrosine antibody was carried out, and the signal intensity at 42kDa band was quantitized using densitometer. The obtained result was compared by student t-test between the experimental and the control group. The absolute amount of MAPK was measured by immunoblotting with anti-MAPK antibody. Result : The tyrosine phosphorylation of MAPK reached peak at 2 minutes after ECS. However, in the chlorpromazine pre-treated group, the peak level of MAPK tyrosine phosphorylation was significantly attenuated(t=-3.12, df=14, p=0.008) compared to the control. In contrast to this, the absolute amount of MAPK did not differ between the pretreated and the control group. Conclusion : Chlorpromazine attenuated the tyrosine phosphorylation of MAPK by ECS. This finding seems to be related to the fact that chlorpromazine pre-treatment changed the cfos expression by ECS in rat brain. Antipsychotic drug and ECS might interact at the level of MAPK signal transduction system, and this might explained the observed synergistic effect of two treatment modality.
Generalized variational inequalities on H-spaces
김훈주 대불대학교 1995 論文集 Vol.1 No.2
위상선형공간의 볼록공간집합의 개념을 일반화하는 연구가 KKM 이론, 부동점이론, 일치점이론등에서 매우 활발하였다. 그 중 Horvath에 의해 도입된 H-공간상에서 여러가지 변분부등식을 얻었다. 이 변분부등식은 Ding 과 Tan, Kim 과 Tan, Park Browder 등의 연구를 일반화한 것이다. In this note, we prove some variational inequalities which generalize Ding and Tan [DT], Kim and Tan [KT], Park [P2] and Browder [Br].
宋柱葉,白東勳,崔淏盛 全北大學校 1996 論文集 Vol.42 No.-
This study was carried out to investigate overall performance and to estimate effects of the environmental factors on body weights of the bull in Korean Native Cattle. Data used for this study included a total of 545 heads of Korean Native Cattle recorded from 1981 to 1990 at Alpine Experiment Station located in Kangwon province. The effects of year of birth, age of dam, parity of dam and season of birth were estimated by means of least squares method. Overall least squares means and standard errors for the body weights of the bull at birth, 4, 6, 12 and 18 months of ate were 26.8±0.13, 99.3±0.58, 142.4±0.80, 338.0±1.34 and 484.2±2.00㎏, respectively. The effects of year of birth showed significant differences on birth weigh and highly significant differences on the other traits. The effects of age of dam showed significant differences on 4 months of age. The effects of season of birth showed significant differences on all of the traits. the calves born in winter or spring were heavier than those born in summer or fall.
김수훈,김상범,김주성,허강인 東亞大學校 附設 情報通信硏究所 1996 情報通信硏究所論文誌 Vol.4 No.1
The exsiting CHMM is hard to express time-transient-variation. To solve such problem, we proposed a new method that is the hybrid network of the feed-forward networks and the HMM. The network is trained to predict the feature vector, varies in each time, is used instead of the mean vector in the HMM, Hence the dynamic feature of speech pattern is provided for the HMM. At the experiment, we compared the result of CHMM+MCEP, CHMM+MIX with NNPHMM. At the result, we got the recognition rates of 73.8% for NNPHMM.
송상훈,심찬섭,이문성,김진오,조주영,김영석,문종호,이진우 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.1
Actinomycosis is an uncommon chronic suppurative disease characterized by multiple abscess, draining sinuses, abundant granulation, and dense fibrous tissue, caused by the actinomyces organisms. It occurs in three major sites: cervicofacial, abdominal, and thoracic. The abdomen is the second most common involved site in previous studies, and there are three ways this organism can affect the gastrointestinal tract: through a blood-borne infection, by swallowing, or by proliferation at a more distal intestinal area. Abdominal actinomycosis is an unusual disease but remains an important differential diagnosis in patients with abdominal mass. Obtaining the diagnosis is difficult and rarely made preoperatively, but provide the key to its management. Medical therapy is effetive in eradicating the disease; however, because of the large amount of reactive fibrosis formed by the infection, it requires long-term therapy. Surgical treatment may be essential in many cases, primarily when malignancy cannot be excluded or if extensive necrotic tissue exists. There are a few description for actinomycosis involving omentum. We report a case of patient with omental actinomycosis, suspected to have a malignancy requiring an exploratory laparotomy with resection.